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A single β-octyl glucoside molecule induces HIV-1 Nef dimer formation in the absence of partner protein binding.

artículo científico publicado en 2018

C-terminal Src kinase-homologous kinase (CHK), a unique inhibitor inactivating multiple active conformations of Src family tyrosine kinases

artículo científico publicado en 2006

C-terminal Src kinase-homologous kinase (CHK), a unique inhibitor inactivating multiple active conformations of Src family tyrosine kinases

artículo científico publicado en 2015

Cell-based Fluorescence Complementation Reveals a Role for HIV-1 Nef Protein Dimerization in AP-2 Adaptor Recruitment and CD4 Co-receptor Down-regulation

artículo científico publicado en 2016

Chemical library screens targeting an HIV-1 accessory factor/host cell kinase complex identify novel antiretroviral compounds

artículo científico publicado en 2009

Csk-homologous kinase (Chk) is an efficient inhibitor of Src-family kinases but a poor catalyst of phosphorylation of their C-terminal regulatory tyrosine

artículo científico publicado en 2017

Dual inhibition of Fes and Flt3 tyrosine kinases potently inhibits Flt3-ITD+ AML cell growth

artículo científico publicado en 2017

Dynamics of the Tec-family tyrosine kinase SH3 domains

artículo científico publicado en 2016

Expression of myeloid Src-family kinases is associated with poor prognosis in AML and influences Flt3-ITD kinase inhibitor acquired resistance

scientific article published on 02 December 2019

Hydrogen Exchange Mass Spectrometry of Related Proteins with Divergent Sequences: A Comparative Study of HIV-1 Nef Allelic Variants

artículo científico publicado en 2016

Inhibition of histone deacetylase expands the renal progenitor cell population

artículo científico publicado en 2010

Nef Homodimers Downregulate SERINC5 by AP-2-Mediated Endocytosis to Promote HIV-1 Infectivity

artículo científico publicado en 2020

Phosphorylation of TNF-alpha converting enzyme by gastrin-releasing peptide induces amphiregulin release and EGF receptor activation.

artículo científico publicado en 2006

Remodeling of HIV-1 Nef Structure by Src-Family Kinase Binding.

artículo científico publicado en 2017

Selective inhibition of the myeloid Src-family kinase Fgr potently suppresses AML cell growth in vitro and in vivo.

artículo científico publicado en 2018

Small molecule inhibition of HIV-1-induced MHC-I down-regulation identifies a temporally regulated switch in Nef action

artículo científico publicado en 2010

Structure, function, and inhibitor targeting of HIV-1 Nef-effector kinase complexes

scientific article published on 29 August 2020

Subtle Dynamic Changes Accompany Hck Activation by HIV-1 Nef and are Reversed by an Antiretroviral Kinase Inhibitor

artículo científico publicado en 2015

Synthesis and evaluation of orally active small molecule HIV-1 Nef antagonists

artículo científico publicado en 2016

The Src family kinase Fgr is a transforming oncoprotein that functions independently of SH3-SH2 domain regulation

artículo científico publicado en 2018

Tight-Binding Hydroxypyrazole HIV-1 Nef Inhibitors Suppress Viral Replication in Donor Mononuclear Cells and Reverse Nef-Mediated MHC-I Downregulation

scientific article published on 16 December 2019

Zebrafish chemical screening reveals an inhibitor of Dusp6 that expands cardiac cell lineages

artículo científico publicado en 2009

c-Abl Tyrosine Kinase Adopts Multiple Active Conformational States in Solution

artículo científico publicado en 2016