Lista de obras -

An Aromatic Cluster in the Active Site of <i>epi</i>-Isozizaene Synthase Is an Electrostatic Toggle for Divergent Terpene Cyclization Pathways

artículo científico publicado en 2020

Binding of N8-Acetylspermidine Analogues to Histone Deacetylase 10 Reveals Molecular Strategies for Blocking Polyamine Deacetylation

scientific article published on 02 December 2019

Binding of inhibitors to active-site mutants of CD1, the enigmatic catalytic domain of histone deacetylase 6

artículo científico publicado en 2020

Binding of the Microbial Cyclic Tetrapeptide Trapoxin A to the Class I Histone Deacetylase HDAC8.

artículo científico publicado en 2017

Carbonic Anhydrase: Evolution of the Zinc Binding Site by Nature and by Design

article

Correction to Structural and Chemical Biology of Terpenoid Cyclases

artículo científico publicado en 2018

Crystal Structure of Cucumene Synthase, a Terpenoid Cyclase That Generates a Linear Triquinane Sesquiterpene

scientific article published on 22 October 2018

Discovery of the First-in-Class Dual Histone Deacetylase-Proteasome Inhibitor

artículo científico publicado en 2018

Entropy as a Driver of Selectivity for Inhibitor Binding to Histone Deacetylase 6

artículo científico publicado en 2018

Exploring Structural Determinants of Inhibitor Affinity and Selectivity in Complexes with Histone Deacetylase 6

scientific article published on 19 December 2019

Exploring the Influence of Domain Architecture on the Catalytic Function of Diterpene Synthases.

artículo científico publicado en 2017

Histone Deacetylase 6-Selective Inhibitors and the Influence of Capping Groups on Hydroxamate-Zinc Denticity

scientific article published on 17 August 2018

Multicomponent Synthesis and Binding Mode of Imidazo[1,2- a]pyridine-Capped Selective HDAC6 Inhibitors

scientific article published on 23 May 2018

Phosphorylation of Histone Deacetylase 8: Structural and Mechanistic Analysis of the Phosphomimetic S39E Mutant

artículo científico publicado en 2019

Polyamine Deacetylase Structure and Catalysis: Prokaryotic Acetylpolyamine Amidohydrolase and Eukaryotic HDAC10

artículo científico publicado en 2018

Structural Basis of Catalysis and Inhibition of HDAC6 CD1, the Enigmatic Catalytic Domain of Histone Deacetylase 6

scientific article published on 02 December 2019

Structural Basis of Tryptophan Reverse N-Prenylation Catalyzed by CymD

artículo científico publicado en 2019

Structural and Chemical Biology of Terpenoid Cyclases.

artículo científico publicado en 2017

Structural insight on assembly-line catalysis in terpene biosynthesis

artículo científico publicado en 2021

Structural studies of geranylgeranylglyceryl phosphate synthase, a prenyltransferase found in thermophilic Euryarchaeota

scientific article published on 29 May 2020

Structure and Function of the Acetylpolyamine Amidohydrolase from the Deep Earth Halophile Marinobacter subterrani

scientific article published on 27 August 2019

Structure of Sesquisabinene Synthase 1, a Terpenoid Cyclase That Generates a Strained [3.1.0] Bridged-Bicyclic Product

scientific article published on 17 April 2019

Substitution of Aromatic Residues with Polar Residues in the Active Site Pocket of epi-Isozizaene Synthase Leads to the Generation of New Cyclic Sesquiterpenes.

artículo científico publicado en 2017

Synthesis and Biological Investigation of Phenothiazine-Based Benzhydroxamic Acids as Selective Histone Deacetylase 6 Inhibitors

scientific article published on 01 February 2019

Lista de obras de

An Aromatic Cluster in the Active Site of <i>epi</i>-Isozizaene Synthase Is an Electrostatic Toggle for Divergent Terpene Cyclization Pathways

Binding of N8-Acetylspermidine Analogues to Histone Deacetylase 10 Reveals Molecular Strategies for Blocking Polyamine Deacetylation

Binding of inhibitors to active-site mutants of CD1, the enigmatic catalytic domain of histone deacetylase 6

Binding of the Microbial Cyclic Tetrapeptide Trapoxin A to the Class I Histone Deacetylase HDAC8.

Carbonic Anhydrase: Evolution of the Zinc Binding Site by Nature and by Design

Correction to Structural and Chemical Biology of Terpenoid Cyclases

Crystal Structure of Cucumene Synthase, a Terpenoid Cyclase That Generates a Linear Triquinane Sesquiterpene

Discovery of the First-in-Class Dual Histone Deacetylase-Proteasome Inhibitor

Entropy as a Driver of Selectivity for Inhibitor Binding to Histone Deacetylase 6

Exploring Structural Determinants of Inhibitor Affinity and Selectivity in Complexes with Histone Deacetylase 6

Exploring the Influence of Domain Architecture on the Catalytic Function of Diterpene Synthases.

Histone Deacetylase 6-Selective Inhibitors and the Influence of Capping Groups on Hydroxamate-Zinc Denticity

Multicomponent Synthesis and Binding Mode of Imidazo[1,2- a]pyridine-Capped Selective HDAC6 Inhibitors

Phosphorylation of Histone Deacetylase 8: Structural and Mechanistic Analysis of the Phosphomimetic S39E Mutant

Polyamine Deacetylase Structure and Catalysis: Prokaryotic Acetylpolyamine Amidohydrolase and Eukaryotic HDAC10

Structural Basis of Catalysis and Inhibition of HDAC6 CD1, the Enigmatic Catalytic Domain of Histone Deacetylase 6

Structural Basis of Tryptophan Reverse N-Prenylation Catalyzed by CymD

Structural and Chemical Biology of Terpenoid Cyclases.

Structural insight on assembly-line catalysis in terpene biosynthesis

Structural studies of geranylgeranylglyceryl phosphate synthase, a prenyltransferase found in thermophilic Euryarchaeota

Structure and Function of the Acetylpolyamine Amidohydrolase from the Deep Earth Halophile Marinobacter subterrani

Structure of Sesquisabinene Synthase 1, a Terpenoid Cyclase That Generates a Strained [3.1.0] Bridged-Bicyclic Product

Substitution of Aromatic Residues with Polar Residues in the Active Site Pocket of epi-Isozizaene Synthase Leads to the Generation of New Cyclic Sesquiterpenes.

Synthesis and Biological Investigation of Phenothiazine-Based Benzhydroxamic Acids as Selective Histone Deacetylase 6 Inhibitors