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"Direct to Drug" screening as a precision medicine tool in multiple myeloma

scientific article published on 11 May 2020

A validated FISH trisomy index demonstrates the hyperdiploid and nonhyperdiploid dichotomy in MGUS.

artículo científico publicado en 2005

Cytogenetic abnormalities in multiple myeloma: association with disease characteristics and treatment response

artículo científico publicado en 2020

Detailing the genomic landscape of myeloma

artículo científico publicado en 2018

Differences in genomic abnormalities among African individuals with monoclonal gammopathies using calculated ancestry

article

Gene-expression profiling of Waldenstrom macroglobulinemia reveals a phenotype more similar to chronic lymphocytic leukemia than multiple myeloma

artículo científico publicado en 2006

IAP antagonists induce anti-tumor immunity in multiple myeloma.

artículo científico publicado en 2016

Identification of lenalidomide resistance pathways in myeloma and targeted resensitization using cereblon replacement, inhibition of STAT3 or targeting of IRF4

artículo científico publicado en 2019

Implications of MYC Rearrangements in Newly Diagnosed Multiple Myeloma

artículo científico publicado en 2020

Inhibitors of the protein disulfide isomerase family for the treatment of multiple myeloma

article

MYC dysregulation in the progression of multiple myeloma

artículo científico publicado en 2019

Mate pair sequencing outperforms fluorescence in situ hybridization in the genomic characterization of multiple myeloma

scientific article published on 16 December 2019

Microbiota-driven interleukin-17-producing cells and eosinophils synergize to accelerate multiple myeloma progression

scientific article published in Nature Communications

Oncolytic immunotherapy and bortezomib synergy improves survival of refractory multiple myeloma in a preclinical model

artículo científico publicado en 2019

Overexpression of EZH2 in multiple myeloma is associated with poor prognosis and dysregulation of cell cycle control.

artículo científico publicado en 2017

Prediction of immunomodulatory drugs (IMiDs) sensitivity in myeloma via determination of baseline anti-oxidative stress capacity

scientific article published on 05 June 2020

Promiscuous mechanisms underlie the antitumor effects of thalidomide analogs.

artículo científico publicado en 2016

Reprogrammed marrow adipocytes contribute to myeloma-induced bone disease

artículo científico publicado en 2019

Systolic dysfunction associated with carfilzomib use in patients with multiple myeloma.

artículo científico publicado en 2017

The CCND1 c.870G risk allele is enriched in individuals of African ancestry with plasma cell dyscrasias

artículo científico publicado en 2020

The Prognostic Role of MYC Structural Variants Identified by NGS and FISH in Multiple Myeloma

artículo científico publicado en 2021