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6-Hydroxyquinolinium salts differing in the length of alkyl side-chain: synthesis and antimicrobial activity

artículo científico publicado en 2014

7-Methoxytacrine-p-Anisidine Hybrids as Novel Dual Binding Site Acetylcholinesterase Inhibitors for Alzheimer's Disease Treatment.

artículo científico publicado en 2015

A 7-methoxytacrine-4-pyridinealdoxime hybrid as a novel prophylactic agent with reactivation properties in organophosphate intoxication

artículo científico publicado en 2016

Butyrylcholinesterase inhibited by nerve agents is efficiently reactivated with chlorinated pyridinium oximes

scientific article published on 18 April 2019

Donepezil Derivatives Targeting Amyloid-β Cascade in Alzheimer's Disease

scientific article published on 01 January 2019

Effects of Novel Tacrine Derivatives on Mitochondrial Energy Metabolism and Monoamine Oxidase Activity-In Vitro Study

artículo científico publicado en 2020

Highly hydrophilic cationic gold nanorods stabilized by novel quaternary ammonium surfactant with negligible cytotoxicity

scientific article published on 23 July 2019

In vitro and in silico evaluation of non-quaternary reactivators of AChE as antidotes of organophosphorus poisoning - a new hope or a blind alley?

artículo científico publicado en 2018

Ligand-based 3D QSAR analysis of reactivation potency of mono- and bis-pyridinium aldoximes toward VX-inhibited rat acetylcholinesterase.

artículo científico publicado en 2014

Novel Group of AChE Reactivators-Synthesis, In Vitro Reactivation and Molecular Docking Study

artículo científico publicado en 2018

Oxime K203: a drug candidate for the treatment of tabun intoxication

scientific article published on 18 December 2018

Profiling donepezil template into multipotent hybrids with antioxidant properties

artículo científico publicado en 2018

Progress in acetylcholinesterase reactivators and in the treatment of organophosphorus intoxication: a patent review (2006-2016).

artículo científico publicado en 2017

Pyridinium oximes with ortho-positioned chlorine moiety exhibit improved physicochemical properties and efficient reactivation of human acetylcholinesterase inhibited by several nerve agents

artículo científico publicado en 2018

Pyridinium-2-carbaldoximes with quinolinium carboxamide moiety are simultaneous reactivators of acetylcholinesterase and butyrylcholinesterase inhibited by nerve agent surrogates

artículo científico publicado en 2021

Rational Design of a New Class of Toll-Like Receptor 4 (TLR4) Tryptamine Related Agonists by Means of the Structure- and Ligand-Based Virtual Screening for Vaccine Adjuvant Discovery.

artículo científico publicado en 2018

Rational design of novel TLR4 ligands by in silico screening and their functional and structural characterization in vitro.

artículo científico publicado en 2018

SAR study to find optimal cholinesterase reactivator against organophosphorous nerve agents and pesticides.

artículo científico publicado en 2016

Structural Properties of Potential Synthetic Vaccine Adjuvants - TLR Agonists.

artículo científico

Synthesis and disinfection effect of the pyridine-4-aldoxime based salts.

artículo científico publicado en 2015

Synthesis, antimicrobial evaluation and molecular modeling of 5-hydroxyisoquinolinium salt series; the effect of the hydroxyl moiety

artículo científico publicado en 2016

Synthesis, in vitro screening and molecular docking of isoquinolinium-5-carbaldoximes as acetylcholinesterase and butyrylcholinesterase reactivators

scientific article published on 01 December 2020

Tacrine-Trolox Hybrids: A Novel Class of Centrally Active, Nonhepatotoxic Multi-Target-Directed Ligands Exerting Anticholinesterase and Antioxidant Activities with Low In Vivo Toxicity.

artículo científico publicado en 2015

The wide-spectrum antimicrobial effect of novel N-alkyl monoquaternary ammonium salts and their mixtures; the QSAR study against bacteria

scientific article published on 19 July 2020

Towards understanding the mechanism of action of antibacterial N-alkyl-3-hydroxypyridinium salts: Biological activities, molecular modeling and QSAR studies

artículo científico publicado en 2016

Wide-Antimicrobial Spectrum of Picolinium Salts

scientific article published on 11 May 2020

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