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CaMKII-mediated phosphorylation of RyR2 plays a crucial role in aberrant Ca2+ release as an arrhythmogenic substrate in cardiac troponin T-related familial hypertrophic cardiomyopathy.

artículo científico publicado en 2018

Dantrolene prevents ventricular tachycardia by stabilizing the ryanodine receptor in pressure- overload induced failing hearts

scientific article published on 18 October 2019

Enhancing calmodulin binding to cardiac ryanodine receptor completely inhibits pressure-overload induced hypertrophic signaling

scientific article published on 26 November 2020

Low-Dose β-Blocker in Combination With Milrinone Safely Improves Cardiac Function and Eliminates Pulsus Alternans in Patients With Acute Decompensated Heart Failure

artículo científico publicado el 5 de abril de 2012

Simultaneous Doppler Tracing of Transmitral Inflow and Mitral Annular Velocity as an Estimate of Elevated Left Ventricular Filling Pressure in Patients With Atrial Fibrillation

artículo científico publicado el 28 de diciembre de 2011

Urinary 8-Hydroxy-2'-Deoxyguanosine as a Novel Biomarker for Predicting Cardiac Events and Evaluating the Effectiveness of Carvedilol Treatment in Patients With Chronic Systolic Heart Failure

artículo científico publicado el 19 de octubre de 2011

Urinary 8‐hydroxy‐2′‐deoxyguanosine reflects symptomatic status and severity of systolic dysfunction in patients with chronic heart failure

artículo científico publicado el 20 de octubre de 2010