Lista de obras -

A comparative phenotypic and genomic analysis of C57BL/6J and C57BL/6N mouse strains

artículo científico publicado en 2013

A large scale hearing loss screen reveals an extensive unexplored genetic landscape for auditory dysfunction.

artículo científico publicado en 2017

A lentiviral vector-based insertional mutagenesis screen identifies mechanisms of resistance to MAPK inhibitors in melanoma

artículo científico publicado en 2018

Accelerating functional gene discovery in osteoarthritis

artículo científico publicado en 2021

Analysis of CRISPR-Cas9 screens identify genetic dependencies in melanoma

artículo científico publicado en 2020

Analysis of mammalian gene function through broad-based phenotypic screens across a consortium of mouse clinics

artículo científico publicado en 2015

Association of the POT1 Germline Missense Variant p.I78T With Familial Melanoma

Astroglial IFITM3 mediates neuronal impairments following neonatal immune challenge in mice

artículo científico publicado en 2013

CRISPR activation screen in mice identifies novel membrane proteins enhancing pulmonary metastatic colonisation

scientific article published on 23 March 2021

Collateral damage and CRISPR genome editing

scientific article published on 14 March 2019

Common and distinct transcriptional signatures of mammalian embryonic lethality

artículo científico publicado en 2019

Corrigendum: High-throughput discovery of novel developmental phenotypes.

artículo científico publicado en 2017

Cross-species oncogenomics offers insight into human muscle-invasive bladder cancer

artículo científico publicado en 2023

Cut-like homeobox 1 (CUX1) tumor suppressor gene haploinsufficiency induces apoptosis evasion to sustain myeloid leukemia

artículo científico publicado en 2021

DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage

artículo científico publicado en 2006

Disease model discovery from 3,328 gene knockouts by The International Mouse Phenotyping Consortium.

artículo científico publicado en 2017

Dissecting the early steps of MLL induced leukaemogenic transformation using a mouse model of AML

artículo científico publicado en 2020

Eros is a novel transmembrane protein that controls the phagocyte respiratory burst and is essential for innate immunity

artículo científico publicado en 2017

Genomic analysis and clinical management of adolescent cutaneous melanoma

artículo científico publicado en 2017

Genomic landscape and clonal architecture of mouse oral squamous cell carcinomas dictate tumour ecology

artículo científico publicado en 2020

Genomics in 2011: challenges and opportunities

artículo científico publicado en 2011

High-throughput phenotyping reveals expansive genetic and structural underpinnings of immune variation

artículo científico publicado en 2019

Highly variable penetrance of abnormal phenotypes in embryonic lethal knockout mice

artículo científico publicado en 2016

Human and mouse essentiality screens as a resource for disease gene discovery

artículo científico publicado en 2020

Identification of FoxR2 as an oncogene in medulloblastoma

artículo científico publicado en 2014

Identification of gut microbial species linked with disease variability in a widely used mouse model of colitis

artículo científico publicado en 2022

Induced mitotic recombination: a switch in time ⬇️

artículo científico publicado el 1 de enero de 2002

Loss of TSLC1 causes male infertility due to a defect at the spermatid stage of spermatogenesis

artículo científico publicado en 2006

Melanoma predisposition-A limited role for germline BRCA1 and BRCA2 variants

artículo científico publicado en 2019

Melanoma subtypes: genomic profiles, prognostic molecular markers and therapeutic possibilities

scientific article published on 15 February 2019

Modeling methyl-sensitive transcription factor motifs with an expanded epigenetic alphabet

artículo científico publicado en 2024

Mouse genomic variation and its effect on phenotypes and gene regulation

artículo científico publicado en 2011

Mouse protein coding diversity: What's left to discover?

scientific article published on 14 November 2019

Multi-site clonality analysis uncovers pervasive heterogeneity across melanoma metastases

artículo científico publicado en 2020

Mutational signatures in tumours induced by high and low energy radiation in Trp53 deficient mice

scientific article published on 20 January 2020

Mutations in FAM50A suggest that Armfield XLID syndrome is a spliceosomopathy

scientific article published on 23 July 2020

No unexpected CRISPR-Cas9 off-target activity revealed by trio sequencing of gene-edited mice

artículo científico publicado en 2018

Normal germ line establishment in mice carrying a deletion of the Ifitm/Fragilis gene family cluster

artículo científico publicado en 2008

Osteocyte transcriptome mapping identifies a molecular landscape controlling skeletal homeostasis and susceptibility to skeletal disease

artículo científico publicado en 2021

Pulmonary metastatic colonisation and granulomas in NOX2-deficient mice

scientific article published on 19 September 2018

Revisiting olfactory receptors as putative drivers of cancer

artículo científico publicado en 2017

Spontaneously occurring melanoma in animals and their relevance to human melanoma

artículo científico publicado en 2020

Synthetic lethality: emerging targets and opportunities in melanoma

artículo científico publicado en 2017

The Deep Genome Project

scientific article published on 03 February 2020

The mutational landscape of melanoma brain metastases presenting as the first visceral site of recurrence

artículo científico publicado en 2020

The mutational signature profile of known and suspected human carcinogens in mice

artículo científico publicado en 2020

Transposon Mutagenesis Reveals RBMS3 Silencing as a Promoter of Malignant Progression of BRAFV600E-Driven Lung Tumorigenesis

artículo científico publicado en 2022

Transposon mutagenesis identifies genes and evolutionary forces driving gastrointestinal tract tumor progression

artículo científico publicado en 2015

Transposon mutagenesis identifies genes that transform neural stem cells into glioma-initiating cells

artículo científico publicado en 2012

Tumors induce de novo steroid biosynthesis in T cells to evade immunity

artículo científico publicado en 2020

Tumour gene expression signature in primary melanoma predicts long-term outcomes

artículo científico publicado en 2021

ZMYM2 inhibits NANOG-mediated reprogramming

scientific article published on 06 June 2019

Lista de obras de

A comparative phenotypic and genomic analysis of C57BL/6J and C57BL/6N mouse strains

A large scale hearing loss screen reveals an extensive unexplored genetic landscape for auditory dysfunction.

A lentiviral vector-based insertional mutagenesis screen identifies mechanisms of resistance to MAPK inhibitors in melanoma

Accelerating functional gene discovery in osteoarthritis

Analysis of CRISPR-Cas9 screens identify genetic dependencies in melanoma

Analysis of mammalian gene function through broad-based phenotypic screens across a consortium of mouse clinics

Association of the POT1 Germline Missense Variant p.I78T With Familial Melanoma

Astroglial IFITM3 mediates neuronal impairments following neonatal immune challenge in mice

CRISPR activation screen in mice identifies novel membrane proteins enhancing pulmonary metastatic colonisation

Collateral damage and CRISPR genome editing

Common and distinct transcriptional signatures of mammalian embryonic lethality

Corrigendum: High-throughput discovery of novel developmental phenotypes.

Cross-species oncogenomics offers insight into human muscle-invasive bladder cancer

Cut-like homeobox 1 (CUX1) tumor suppressor gene haploinsufficiency induces apoptosis evasion to sustain myeloid leukemia

DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage

Disease model discovery from 3,328 gene knockouts by The International Mouse Phenotyping Consortium.

Dissecting the early steps of MLL induced leukaemogenic transformation using a mouse model of AML

Eros is a novel transmembrane protein that controls the phagocyte respiratory burst and is essential for innate immunity

Genomic analysis and clinical management of adolescent cutaneous melanoma

Genomic landscape and clonal architecture of mouse oral squamous cell carcinomas dictate tumour ecology

Genomics in 2011: challenges and opportunities

High-throughput phenotyping reveals expansive genetic and structural underpinnings of immune variation

Highly variable penetrance of abnormal phenotypes in embryonic lethal knockout mice

Human and mouse essentiality screens as a resource for disease gene discovery

Identification of FoxR2 as an oncogene in medulloblastoma

Identification of gut microbial species linked with disease variability in a widely used mouse model of colitis

Induced mitotic recombination: a switch in time ⬇️

Loss of TSLC1 causes male infertility due to a defect at the spermatid stage of spermatogenesis

Melanoma predisposition-A limited role for germline BRCA1 and BRCA2 variants

Melanoma subtypes: genomic profiles, prognostic molecular markers and therapeutic possibilities

Modeling methyl-sensitive transcription factor motifs with an expanded epigenetic alphabet

Mouse genomic variation and its effect on phenotypes and gene regulation

Mouse protein coding diversity: What's left to discover?

Multi-site clonality analysis uncovers pervasive heterogeneity across melanoma metastases

Mutational signatures in tumours induced by high and low energy radiation in Trp53 deficient mice

Mutations in FAM50A suggest that Armfield XLID syndrome is a spliceosomopathy

No unexpected CRISPR-Cas9 off-target activity revealed by trio sequencing of gene-edited mice

Normal germ line establishment in mice carrying a deletion of the Ifitm/Fragilis gene family cluster

Osteocyte transcriptome mapping identifies a molecular landscape controlling skeletal homeostasis and susceptibility to skeletal disease

Pulmonary metastatic colonisation and granulomas in NOX2-deficient mice

Revisiting olfactory receptors as putative drivers of cancer

Spontaneously occurring melanoma in animals and their relevance to human melanoma

Synthetic lethality: emerging targets and opportunities in melanoma

The Deep Genome Project

The mutational landscape of melanoma brain metastases presenting as the first visceral site of recurrence

The mutational signature profile of known and suspected human carcinogens in mice

Transposon Mutagenesis Reveals RBMS3 Silencing as a Promoter of Malignant Progression of BRAFV600E-Driven Lung Tumorigenesis

Transposon mutagenesis identifies genes and evolutionary forces driving gastrointestinal tract tumor progression

Transposon mutagenesis identifies genes that transform neural stem cells into glioma-initiating cells

Tumors induce de novo steroid biosynthesis in T cells to evade immunity

Tumour gene expression signature in primary melanoma predicts long-term outcomes

ZMYM2 inhibits NANOG-mediated reprogramming