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A European perspective on alternatives to animal testing for environmental hazard identification and risk assessment

artículo científico publicado en 2013

A fish intestinal epithelial barrier model established from the rainbow trout (Oncorhynchus mykiss) cell line, RTgutGC.

artículo científico publicado en 2017

A validated algorithm for selecting non-toxic chemical concentrations

artículo científico publicado en 2017

Abcb4 acts as multixenobiotic transporter and active barrier against chemical uptake in zebrafish (Danio rerio) embryos

artículo científico publicado en 2013

Addressing chemical pollution in biodiversity research

artículo científico publicado en 2023

Adverse outcome pathways during early fish development: a conceptual framework for identification of chemical screening and prioritization strategies

artículo científico publicado en 2011

Agglomeration of tungsten carbide nanoparticles in exposure medium does not prevent uptake and toxicity toward a rainbow trout gill cell line

artículo científico publicado en 2009

Alternative approaches to vertebrate ecotoxicity tests in the 21st century: A review of developments over the last 2 decades and current status

artículo científico publicado en 2016

Ammonia-containing industrial effluents, lethal to rainbow trout, induce vacuolisation and Neutral Red uptake in the rainbow trout gill cell line, RTgill-W1.

artículo científico publicado en 2009

An interlaboratory comparison of nanosilver characterisation and hazard identification: Harmonising techniques for high quality data

artículo científico publicado en 2015

Analysis of estrogenic effects by quantification of green fluorescent protein in juvenile fish of a transgenic medaka

artículo científico publicado en 2005

Anthropogenic Chemicals As Underestimated Drivers of Biodiversity Loss: Scientific and Societal Implications

artículo científico publicado en 2022

Application of Alamar blue/5-carboxyfluorescein diacetate acetoxymethyl ester as a noninvasive cell viability assay in primary hepatocytes from rainbow trout

artículo científico publicado en 2005

Applying whole water samples to cell bioassays for detecting dioxin-like compounds at contaminated sites.

artículo científico publicado en 2004

Applying whole-water samples directly to fish cell cultures in order to evaluate the toxicity of industrial effluent

artículo científico publicado en 2002

Assessing the bioaccumulation potential of ionizable organic compounds: Current knowledge and research priorities.

artículo científico publicado en 2016

Bacterial lipopolysaccharides induce genes involved in the innate immune response in embryos of the zebrafish (Danio rerio).

artículo científico publicado en 2007

Biotransformation capacity of zebrafish (Danio rerio) early life stages: Functionality of the mercapturic acid pathway

artículo científico publicado en 2020

Biotransformation of benzo(a)pyrene by three rainbow trout (Onchorhynchus mykiss) cell lines and extrapolation to derive a fish bioconcentration factor.

artículo científico publicado en 2018

Cell culture-based biosensing techniques for detecting toxicity in water

artículo científico publicado en 2017

Cell-based data to predict the toxicity of chemicals to fish. Commentary on the manuscript by Rodrigues et al., 2019. Cell-based assays seem not to accurately predict fish short-term toxicity of pesticides. Environmental Pollution 252:476-482

scientific article published on 01 November 2019

Chapter 12 Use of ceramic dosimeters in water monitoring

Chapter 18 Use of passive sampling devices in toxicity assessment of groundwater

article

Characterization of the mercapturic acid pathway, an important phase II biotransformation route, in a zebrafish embryo cell line

artículo científico publicado en 2020

Chemical Aspects of Nanoparticle Ecotoxicology.

artículo científico publicado en 2014

Clobetasol propionate causes immunosuppression in zebrafish (Danio rerio) at environmentally relevant concentrations

artículo científico publicado en 2016

Co-exposure to polystyrene plastic beads and polycyclic aromatic hydrocarbon contaminants in fish gill (RTgill-W1) and intestinal (RTgutGC) epithelial cells derived from rainbow trout (Oncorhynchus mykiss)

scientific article published on 22 February 2019

Comment on Schriks, M., Heringa, M.B., van der Kooi, M.M.E., de Voogt, P., van Wezel, A.P., 2010. Toxicological relevance of emerging contaminants for drinking water quality. Water Research 44, 461–476

artículo científico publicado en 2010

Common Gene Expression Patterns in Environmental Model Organisms Exposed to Engineered Nanomaterials: A Meta-Analysis

scientific article published on 13 December 2019

Comparative evaluation of particle properties, formation of reactive oxygen species and genotoxic potential of tungsten carbide based nanoparticles in vitro ⬇️

artículo científico publicado el 5 de mayo de 2012

Comparative study of the sensitivity of two freshwater gastropods, Lymnaea stagnalis and Planorbarius corneus, to silver nanoparticles: bioaccumulation and toxicity

scientific article published in 2022

Constitutive mRNA expression and protein activity levels of nine ABC efflux transporters in seven permanent cell lines derived from different tissues of rainbow trout (Oncorhynchus mykiss).

artículo científico publicado en 2010

Contribution of hepatic cytochrome CYP1A and metallothionein mRNA abundance to biomonitoring-A case study with European flounder (Platichthys flesus) from the Gulf of Gdańsk

artículo científico publicado en 2016

Corrigendum to “European demonstration program on the effect-based and chemical identification and monitoring of organic pollutants in European surface waters” [Sci. Total Environ. 601–602 (2017) 1849–1868]

scientific article published on 05 May 2018

Critical influence of chloride ions on silver ion-mediated acute toxicity of silver nanoparticles to zebrafish embryos.

artículo científico publicado en 2014

Developing a list of reference chemicals for testing alternatives to whole fish toxicity tests.

artículo científico publicado en 2008

Development and application of the adverse outcome pathway framework for understanding and predicting chronic toxicity: I. Challenges and research needs in ecotoxicology.

artículo científico publicado en 2014

Development and application of the adverse outcome pathway framework for understanding and predicting chronic toxicity: II. A focus on growth impairment in fish

artículo científico

Development of a Partition-Controlled Dosing System for Cell Assays ⬇️

artículo científico publicado el 20 de octubre de 2010

Development of a solvent-free, solid-phase in vitro bioassay using vertebrate cells

artículo científico publicado en 2006

Development of mutagenicity during degradation of N-nitrosamines by advanced oxidation processes

artículo científico publicado en 2014

Differential gene expression as a toxicant-sensitive endpoint in zebrafish embryos and larvae

artículo científico

Dioxin-�hnliche Wirkungen durch Grundwasser am Industriestandort Zeitz

Dose-dependent effects of morphine on lipopolysaccharide (LPS)-induced inflammation, and involvement of multixenobiotic resistance (MXR) transporters in LPS efflux in teleost fish.

artículo científico publicado en 2016

EDA-EMERGE: an FP7 initial training network to equip the next generation of young scientists with the skills to address the complexity of environmental contamination with emerging pollutants

scientific article published in 2013

Early life exposure to PCB126 results in delayed mortality and growth impairment in the zebrafish larvae

artículo científico publicado en 2015

Ecotoxicological Profiling of Transect River Elbe Sediments

article by Matthias Grote et al published December 2005 in CLEAN - Soil, Air, Water

Effect of TiO2 nanoparticles and UV radiation on extracellular enzyme activity of intact heterotrophic biofilms

artículo científico publicado en 2014

Effect of media composition on bioavailability and toxicity of silver and silver nanoparticles in fish intestinal cells (RTgutGC).

artículo científico publicado en 2016

Effect-directed analysis of mutagens and ethoxyresorufin-o-deethylase inducers in aquatic sediments

artículo científico publicado en 2005

Effect-directed fractionation and identification of cytochrome p4501A-inducing halogenated aromatic hydrocarbons in a contaminated sediment

artículo científico publicado en 2002

Effects of solvents and dosing procedure on chemical toxicity in cell-based in vitro assays

artículo científico publicado en 2010

Endocrine disrupting compounds affecting corticosteroid signaling pathways in Czech and Swiss waters: potential impact on fish

artículo científico publicado en 2014

Erratum to: LC-MS/MS determination of potential endocrine disruptors of cortico signalling in rivers and wastewaters.

artículo científico publicado en 2016

Establishment of the first humpback whale fibroblast cell lines and their application in chemical risk assessment

artículo científico publicado en 2015

European demonstration program on the effect-based and chemical identification and monitoring of organic pollutants in European surface waters

artículo científico

Evaluating environmental risk assessment models for nanomaterials according to requirements along the product innovation Stage-Gate process

article

Evaluating the cytotoxicity of palladium/magnetite nano-catalysts intended for wastewater treatment

artículo científico publicado en 2009

Evaluating the toxicity of Triton X-100 to protozoan, fish, and mammalian cells using fluorescent dyes as indicators of cell viability

artículo científico publicado en 2004

Evolution of algal toxicity during (photo)oxidative degradation of diuron

artículo científico publicado en 2010

Extending the concept of predicting fish acute toxicity in vitro to the intestinal cell line RTgutGC

scientific article published on 11 July 2019

Fish Cell Lines as Rapid and Inexpensive Screening and Supplemental Tools for Whole Effluent Testing

Fish cell lines as rapid and inexpensive screening and supplemental tools for whole effluent testing

artículo científico publicado en 2008

Fish-gut-on-chip: development of a microfluidic bioreactor to study the role of the fish intestine in vitro

artículo científico publicado en 2019

From the Cover: Zebrafish Larvae Are Insensitive to Stimulation by Cocaine: Importance of Exposure Route and Toxicokinetics

artículo científico publicado en 2016

Glutathione S-transferase protein expression in different life stages of zebrafish (Danio rerio).

artículo científico publicado en 2018

Hexachlorobenzene exerts genotoxic effects in a humpback whale cell line under stable exposure conditions

artículo científico

Identification and evaluation of cyp1a transcript expression in fish as molecular biomarker for petroleum contamination in tropical fresh water ecosystems.

artículo científico publicado en 2011

Identification of multi-drug resistance associated proteins MRP1 (ABCC1) and MRP3 (ABCC3) from rainbow trout (Oncorhynchus mykiss).

artículo científico publicado en 2009

Imidacloprid induces adverse effects on fish early life stages that are more severe in Japanese medaka (Oryzias latipes) than in zebrafish (Danio rerio)

artículo científico publicado en 2019

Importance of Toxicokinetics to Assess the Utility of Zebrafish Larvae as Model for Psychoactive Drug Screening Using Meta-Chlorophenylpiperazine (mCPP) as Example.

artículo científico publicado en 2018

Importance of toxicokinetics for interspecies variation in sensitivity to chemicals

artículo científico publicado en 2014

Improving a fish intestinal barrier model by combining two rainbow trout cell lines: epithelial RTgutGC and fibroblastic RTgutF

scientific article published on 29 June 2019

Indicators for assessing anthropogenic impact on urban surface and groundwater

Interaction of silver nanoparticles with algae and fish cells: a side by side comparison.

artículo científico publicado en 2017

Internalisation of engineered nanoparticles into mammalian cells in vitro: influence of cell type and particle properties

article

Intestinal Fish Cell Barrier Model to Assess Transfer of Organic Chemicals in Vitro: An Experimental and Computational Study

artículo científico publicado en 2019

Investigating alternatives to the fish early-life stage test: a strategy for discovering and annotating adverse outcome pathways for early fish development

artículo científico publicado en 2013

LC-APCI(-)-MS Determination of 1-Chloro-2,4-dinitrobenzene, a Model Substrate for Glutathione S-Transferases

scientific article published on 05 February 2020

LC-MS/MS determination of potential endocrine disruptors of cortico signalling in rivers and wastewaters

artículo científico publicado en 2014

Lifetime extension of humpback whale skin fibroblasts and their response to lipopolysaccharide (LPS) and a mixture of polychlorinated biphenyls (Aroclor)

scientific article published on 10 January 2019

Limitations and uncertainties of acute fish toxicity assessments can be reduced using alternative methods

scientific article published on 16 September 2020

Linking toxicity and adaptive responses across the transcriptome, proteome, and phenotype of Chlamydomonas reinhardtii exposed to silver

artículo científico publicado en 2014

MOLECULAR AND PHYLOGENETIC CHARACTERIZATION OFPHORMIDIUM SPECIES (CYANOPROKARYOTA)USING THE CPCB-IGS-CPCA LOCUS

Mass fluxes of xenobiotics below cities: challenges in urban hydrogeology

article by Mario Schirmer et al published 4 December 2010 in Environmental Earth Sciences

Measured and modeled toxicokinetics in cultured fish cells and application to in vitro-in vivo toxicity extrapolation

artículo científico publicado en 2014

Microcystin-LR induced cellular effects in mammalian and fish primary hepatocyte cultures and cell lines: a comparative study

artículo científico publicado en 2005

Mixtures of chemical pollutants at European legislation safety concentrations: how safe are they?

artículo científico publicado en 2014

Modeling the impact of a benzene source zone on the transport behavior of PAHs in groundwater

artículo científico publicado en 2006

Multiple-endpoint assay provides a detailed mechanistic view of responses to herbicide exposure in Chlamydomonas reinhardtii

artículo científico publicado en 2012

Nanomaterials in the Environment: Behavior, Fate, Bioavailability, and Effects-An Updated Review

artículo científico publicado en 2018

Natural attenuation research at the contaminated megasite Zeitz

Nonylphenol isomers differ in estrogenic activity

artículo científico publicado en 2006

Novel test procedure to evaluate the treatability of wastewater with ozone

artículo científico publicado en 2015

Passive Probennahme in Grund- und Oberflächenwasser—Ein Überblick

Passive sampler for combined chemical and toxicological long-term monitoring of groundwater: the ceramic toximeter

artículo científico publicado en 2007

Physical-chemical characterization of tungsten carbide nanoparticles as a basis for toxicological investigations

artículo científico publicado en 2010

Predicting Adult Fish Acute Lethality with the Zebrafish Embryo: Relevance of Test Duration, Endpoints, Compound Properties, and Exposure Concentration Analysis

article

Predicting Fish Acute Toxicity Using a Fish Gill Cell Line-Based Toxicity Assay ⬇️

artículo científico publicado el 27 de diciembre de 2012

Predicting concentrations of organic chemicals in fish by using toxicokinetic models

artículo científico publicado en 2012

Proposal to improve vertebrate cell cultures to establish them as substitutes for the regulatory testing of chemicals and effluents using fish

artículo científico publicado en 2006

Rainbow Trout () Intestinal Epithelial Cells as a Model for Studying Gut Immune Function and Effects of Functional Feed Ingredients

scientific article published on 06 February 2019

Removal of the antiviral agent oseltamivir and its biological activity by oxidative processes ⬇️

artículo científico publicado el 24 de octubre de 2011

Repeatability and Reproducibility of the RTgill-W1 Cell Line Assay for Predicting Fish Acute Toxicity.

artículo científico publicado en 2019

Scientific Basis for Regulatory Decision-Making of Nanomaterials Report on the Workshop, 20-21 January 2014, Center of Applied Ecotoxicology, Dübendorf

artículo científico publicado en 2015

Silver nanoparticle effects on stream periphyton during short-term exposures

artículo científico publicado en 2015

Silver nanoparticles inhibit fish gill cell proliferation in protein-free culture medium.

artículo científico publicado en 2016

Systems toxicology approach to understand the kinetics of benzo(a)pyrene uptake, biotransformation, and DNA adduct formation in a liver cell model

artículo científico publicado en 2014

Systems toxicology: from basic research to risk assessment

artículo científico publicado en 2014

Testing Nanomaterial Toxicity in Unicellular Eukaryotic Algae and Fish Cell Lines ⬇️

artículo científico publicado el 1 de enero de 2013

The A/B domain of the teleost glucocorticoid receptors influences partial nuclear localization in the absence of hormone.

artículo científico publicado en 2008

The freshwater cyanobacterium Lyngbya aerugineo-coerulea produces compounds toxic to mice and to mammalian and fish cells

artículo científico publicado en 2003

The influence of modes of action and physicochemical properties of chemicals on the correlation between in vitro and acute fish toxicity data

artículo científico publicado en 2009

The insecticide imidacloprid causes mortality of the freshwater amphipod Gammarus pulex by interfering with feeding behavior

artículo científico publicado en 2013

The role of cyp1a and heme oxygenase 1 gene expression for the toxicity of 3,4-dichloroaniline in zebrafish (Danio rerio) embryos

artículo científico publicado en 2007

The use of fish-derived cell lines for investigation of environmental contaminants.

artículo científico publicado en 2003

The use of fish-derived cell lines for investigation of environmental contaminants: an update following OECD's fish toxicity testing framework No. 171.

artículo científico publicado en 2013

Time- and concentration-dependent expression of immune and barrier genes in the RTgutGC fish intestinal model following immune stimulation

artículo científico publicado en 2019

Time-integrated monitoring of polycyclic aromatic hydrocarbons (Pahs) in groundwater using the ceramic dosimeter passive sampling device

artículo científico publicado en 2005

Toxic potential of five freshwater Phormidium species (Cyanoprokaryota).

artículo científico publicado en 2005

Toxic potential of microcystin-containing cyanobacterial extracts from three Romanian freshwaters

artículo científico publicado en 2006

Toxicity of silver nanoparticles to a fish gill cell line: role of medium composition

artículo científico publicado en 2014

Toxicity of tungsten carbide and cobalt-doped tungsten carbide nanoparticles in mammalian cells in vitro

artículo científico publicado en 2008

Toxicokinetic-toxicodynamic modelling of survival of Gammarus pulex in multiple pulse exposures to propiconazole: model assumptions, calibration data requirements and predictive power

artículo científico publicado en 2012

Toxicology across scales: Cell population growth in vitro predicts reduced fish growth

artículo científico publicado en 2015

Transcriptional signatures of regulatory and toxic responses to benzo-[a]-pyrene exposure

artículo científico publicado en 2011

Transcriptomics in ecotoxicology

artículo científico publicado en 2010

Transformation of Contaminant Candidate List (CCL3) compounds during ozonation and advanced oxidation processes in drinking water: Assessment of biological effects

artículo científico publicado en 2016

Tungsten carbide and tungsten carbide cobalt nanoparticle toxicity: The role of cellular particle uptake, leached ions and cobalt bioavailability

article

Tungsten carbide cobalt nanoparticles exert hypoxia-like effects on the gene expression level in human keratinocytes

artículo científico publicado en 2010

Ultrathin Alumina Membranes as Scaffold for Epithelial Cell Culture from the Intestine of Rainbow Trout

artículo científico publicado en 2017

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