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Bromodomain-selective BET inhibitors are potent antitumor agents against MYC-driven pediatric cancer

artículo científico publicado en 2020

Cathepsin B modulates lysosomal biogenesis and host defense against Francisella novicida infection.

scientific article published on 22 August 2016

Cohort Profile: The St. Jude Lifetime Cohort Study (SJLIFE) for paediatric cancer survivors

artículo científico publicado en 2020

Critical roles of mTORC1 signaling and metabolic reprogramming for M-CSF-mediated myelopoiesis.

artículo científico publicado en 2017

Discrete roles and bifurcation of PTEN signaling and mTORC1-mediated anabolic metabolism underlie IL-7-driven B lymphopoiesis.

artículo científico publicado en 2018

Efficacy and pharmacokinetic/pharmacodynamic evaluation of the Aurora kinase A inhibitor MLN8237 against preclinical models of pediatric cancer.

artículo científico publicado en 2011

Epigenetic Age Acceleration and Chronic Health Conditions among Adult Survivors of Childhood Cancer

scientific article published on 24 September 2020

Evaluation of a two-step iterative resampling procedure for internal validation of genome-wide association studies

artículo científico publicado en 2015

Evaluation of two-step iterative resampling procedure for internal validation of genome-wide association studies

artículo científico publicado en 2014

Forty-five patient-derived xenografts capture the clinical and biological heterogeneity of Wilms tumor

scientific article published on 20 December 2019

Genetic and clinical factors associated with obesity among adult survivors of childhood cancer: A report from the St. Jude Lifetime Cohort

artículo científico publicado en 2015

Genome-Wide Association Study to Identify Susceptibility Loci That Modify Radiation-Related Risk for Breast Cancer After Childhood Cancer

artículo científico publicado en 2017

Genome-wide interrogation of germline genetic variation associated with treatment response in childhood acute lymphoblastic leukemia

scientific journal article

Germline Elongator mutations in Sonic Hedgehog medulloblastoma

scientific article published on 01 April 2020

Germline genomic variants associated with childhood acute lymphoblastic leukemia

scientific journal article

Homeostasis and transitional activation of regulatory T cells require c-Myc

scientific article published on 01 January 2020

IRF1 Is a Transcriptional Regulator of ZBP1 Promoting NLRP3 Inflammasome Activation and Cell Death during Influenza Virus Infection

artículo científico publicado en 2018

Inherited GATA3 variants are associated with Ph-like childhood acute lymphoblastic leukemia and risk of relapse

artículo científico publicado en 2013

Initial testing (stage 1) of AZD6244 (ARRY-142886) by the Pediatric Preclinical Testing Program.

artículo científico publicado en 2010

Initial testing (stage 1) of the cyclin dependent kinase inhibitor SCH 727965 (dinaciclib) by the pediatric preclinical testing program.

artículo científico publicado en 2012

Interferon inducible GBPs restrict Burkholderia thailandensis motility induced cell-cell fusion

artículo científico publicado en 2020

MYC competes with MiT/TFE in regulating lysosomal biogenesis and autophagy through an epigenetic rheostat

scientific article published on 09 August 2019

Metabolic heterogeneity underlies reciprocal fates of TH17 cell stemness and plasticity.

artículo científico publicado en 2018

Metabolic signaling directs the reciprocal lineage decisions of αβ and γδ T cells

artículo científico publicado en 2018

Molecular characterization of the pediatric preclinical testing panel

artículo científico publicado en 2008

PLCγ-dependent mTOR signalling controls IL-7-mediated early B cell development.

artículo científico publicado en 2017

Relapse-Fated Latent Diagnosis Subclones in Acute B Lineage Leukemia Are Drug Tolerant and Possess Distinct Metabolic Programs

scientific article published on 21 February 2020

SLFN11 is Widely Expressed in Pediatric Sarcoma and Induces Variable Sensitization to Replicative Stress Caused By DNA-Damaging Agents

artículo científico publicado en 2021

Will Attention by Vaccine Developers to the Host's Nuclear Hormone Levels and Immunocompetence Improve Vaccine Success?

article

XAF1 as a modifier of p53 function and cancer susceptibility

scientific article published on 24 June 2020

mTOR coordinates transcriptional programs and mitochondrial metabolism of activated Treg subsets to protect tissue homeostasis.

artículo científico publicado en 2018