Lista de obras -

A Dynamic Switch in Inactive p38γ Leads to an Excited State on the Pathway to an Active Kinase

scientific article published on 13 December 2019

A VH1-69 antibody lineage from an infected Chinese donor potently neutralizes HIV-1 by targeting the V3 glycan supersite

scientific article published on 16 September 2020

A complex epistatic network limits the mutational reversibility in the influenza hemagglutinin receptor-binding site.

artículo científico publicado en 2018

A cross-neutralizing antibody between HIV-1 and influenza virus

artículo científico publicado en 2021

A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses

artículo científico publicado en 2019

A highly conserved cryptic epitope in the receptor-binding domains of SARS-CoV-2 and SARS-CoV

scientific article published on 03 April 2020

A natural mutation between SARS-CoV-2 and SARS-CoV determines neutralization by a cross-reactive antibody

artículo científico publicado en 2020

A natural mutation between SARS-CoV-2 and SARS-CoV determines neutralization by a cross-reactive antibody

artículo científico publicado en 2020

A pan-coronavirus fusion inhibitor targeting the HR1 domain of human coronavirus spike

artículo científico publicado en 2019

A public antibody lineage that potently inhibits malaria infection through dual binding to the circumsporozoite protein.

artículo científico publicado en 2018

A single mutation in Taiwanese H6N1 influenza hemagglutinin switches binding to human-type receptors.

artículo científico publicado en 2017

A small-molecule fusion inhibitor of influenza virus is orally active in mice

artículo científico publicado en 2019

An MPER antibody neutralizes HIV-1 using germline features shared among donors

scientific article published on 26 November 2019

An alternate conformation of HCV E2 neutralizing face as an additional vaccine target

artículo científico publicado en 2020

An alternative binding mode of IGHV3-53 antibodies to the SARS-CoV-2 receptor binding domain

artículo científico publicado en 2020

An influenza A hemagglutinin small-molecule fusion inhibitor identified by a new high-throughput fluorescence polarization screen

artículo científico publicado en 2020

Antibody responses to viral infections: a structural perspective across three different enveloped viruses

artículo científico publicado en 2019

Bacterial glycosyltransferase-mediated cell-surface chemoenzymatic glycan modification

scientific article published on 17 April 2019

Bacterially derived synthetic mimetics of mammalian oligomannose prime antibody responses that neutralize HIV infectivity.

artículo científico publicado en 2017

Broadly protective human antibodies that target the active site of influenza virus neuraminidase

artículo científico publicado en 2019

COVA1-18 neutralizing antibody protects against SARS-CoV-2 in three preclinical models

scientific article published in 2021

Capturing the inherent structural dynamics of the HIV-1 envelope glycoprotein fusion peptide

artículo científico publicado en 2019

Computational design of trimeric influenza-neutralizing proteins targeting the hemagglutinin receptor binding site.

artículo científico publicado en 2017

Cross-neutralization of a SARS-CoV-2 antibody to a functionally conserved site is mediated by avidity

scientific article published on 03 August 2020

Cryo-EM structure of circumsporozoite protein with a vaccine-elicited antibody is stabilized by somatically mutated inter-Fab contacts

scientific article published on 10 October 2018

Design of protein-binding proteins from the target structure alone

artículo científico publicado en 2022

Different genetic barriers for resistance to HA stem antibodies in influenza H3 and H1 viruses

scientific article published on 01 June 2020

Epitopes for neutralizing antibodies induced by HIV-1 envelope glycoprotein BG505 SOSIP trimers in rabbits and macaques.

artículo científico publicado en 2018

Functional human IgA targets a conserved site on malaria sporozoites

artículo científico publicado en 2021

Genetic and structural insights into broad neutralization of hepatitis C virus by human V1-69 antibodies

scientific article published on 02 January 2019

HIV-1 vaccine design through minimizing envelope metastability

article

Inhibitory antibodies identify unique sites of therapeutic vulnerability in rhinovirus and other enteroviruses

artículo científico publicado en 2020

Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model

artículo científico publicado en 2020

Lipid interactions and angle of approach to the HIV-1 viral membrane of broadly neutralizing antibody 10E8: Insights for vaccine and therapeutic design.

artículo científico publicado en 2017

Major antigenic site B of human influenza H3N2 viruses has an evolving local fitness landscape

scientific article published on 06 March 2020

Potent anti-influenza H7 human monoclonal antibody induces separation of hemagglutinin receptor-binding head domains

artículo científico publicado en 2019

Potent peptidic fusion inhibitors of influenza virus

artículo científico publicado en 2017

Probing the antigenicity of hepatitis C virus envelope glycoprotein complex by high-throughput mutagenesis

artículo científico publicado en 2017

Proof of concept for rational design of hepatitis C virus E2 core nanoparticle vaccines

scientific article published on 15 April 2020

Selection of a picomolar antibody that targets CXCR2-mediated neutrophil activation and alleviates EAE symptoms

artículo científico publicado en 2021

Single-component multilayered self-assembling nanoparticles presenting rationally designed glycoprotein trimers as Ebola virus vaccines

artículo científico publicado en 2021

Structural Biology of Influenza Hemagglutinin: An Amaranthine Adventure

scientific article published on 22 September 2020

Structural and biophysical correlation of anti-NANP antibodies with in vivo protection against P. falciparum

artículo científico publicado en 2021

Structural basis of a shared antibody response to SARS-CoV-2

artículo científico publicado en 2020

Structural basis of broad HIV neutralization by a vaccine-induced cow antibody

artículo científico publicado en 2020

Structural insights of a highly potent pan-neutralizing SARS-CoV-2 human monoclonal antibody

scientific article published on 12 May 2022

Structure and immunogenicity of a stabilized HIV-1 envelope trimer based on a group-M consensus sequence

scientific article published on 29 May 2019

Structure and mechanism of monoclonal antibody binding to the junctional epitope of Plasmodium falciparum circumsporozoite protein

artículo científico publicado en 2020

Structure of a cleavage-independent HIV Env recapitulates the glycoprotein architecture of the native cleaved trimer.

artículo científico publicado en 2018

Structures of single-layer β-sheet proteins evolved from β-hairpin repeats

artículo científico publicado en 2019

Synthetic development of a broadly neutralizing antibody against snake venom long-chain α-neurotoxins

artículo científico publicado en 2024

The human naive B cell repertoire contains distinct subclasses for a germline-targeting HIV-1 vaccine immunogen

article

Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin

artículo científico publicado en 2018

Vulnerabilities in coronavirus glycan shields despite extensive glycosylation

artículo científico publicado en 2020

Lista de obras de

A Dynamic Switch in Inactive p38γ Leads to an Excited State on the Pathway to an Active Kinase

A VH1-69 antibody lineage from an infected Chinese donor potently neutralizes HIV-1 by targeting the V3 glycan supersite

A complex epistatic network limits the mutational reversibility in the influenza hemagglutinin receptor-binding site.

A cross-neutralizing antibody between HIV-1 and influenza virus

A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses

A highly conserved cryptic epitope in the receptor-binding domains of SARS-CoV-2 and SARS-CoV

A natural mutation between SARS-CoV-2 and SARS-CoV determines neutralization by a cross-reactive antibody

A natural mutation between SARS-CoV-2 and SARS-CoV determines neutralization by a cross-reactive antibody

A pan-coronavirus fusion inhibitor targeting the HR1 domain of human coronavirus spike

A public antibody lineage that potently inhibits malaria infection through dual binding to the circumsporozoite protein.

A single mutation in Taiwanese H6N1 influenza hemagglutinin switches binding to human-type receptors.

A small-molecule fusion inhibitor of influenza virus is orally active in mice

An MPER antibody neutralizes HIV-1 using germline features shared among donors

An alternate conformation of HCV E2 neutralizing face as an additional vaccine target

An alternative binding mode of IGHV3-53 antibodies to the SARS-CoV-2 receptor binding domain

An influenza A hemagglutinin small-molecule fusion inhibitor identified by a new high-throughput fluorescence polarization screen

Antibody responses to viral infections: a structural perspective across three different enveloped viruses

Bacterial glycosyltransferase-mediated cell-surface chemoenzymatic glycan modification

Bacterially derived synthetic mimetics of mammalian oligomannose prime antibody responses that neutralize HIV infectivity.

Broadly protective human antibodies that target the active site of influenza virus neuraminidase

COVA1-18 neutralizing antibody protects against SARS-CoV-2 in three preclinical models

Capturing the inherent structural dynamics of the HIV-1 envelope glycoprotein fusion peptide

Computational design of trimeric influenza-neutralizing proteins targeting the hemagglutinin receptor binding site.

Cross-neutralization of a SARS-CoV-2 antibody to a functionally conserved site is mediated by avidity

Cryo-EM structure of circumsporozoite protein with a vaccine-elicited antibody is stabilized by somatically mutated inter-Fab contacts

Design of protein-binding proteins from the target structure alone

Different genetic barriers for resistance to HA stem antibodies in influenza H3 and H1 viruses

Epitopes for neutralizing antibodies induced by HIV-1 envelope glycoprotein BG505 SOSIP trimers in rabbits and macaques.

Functional human IgA targets a conserved site on malaria sporozoites

Genetic and structural insights into broad neutralization of hepatitis C virus by human V1-69 antibodies

HIV-1 vaccine design through minimizing envelope metastability

Inhibitory antibodies identify unique sites of therapeutic vulnerability in rhinovirus and other enteroviruses

Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model

Lipid interactions and angle of approach to the HIV-1 viral membrane of broadly neutralizing antibody 10E8: Insights for vaccine and therapeutic design.

Major antigenic site B of human influenza H3N2 viruses has an evolving local fitness landscape

Potent anti-influenza H7 human monoclonal antibody induces separation of hemagglutinin receptor-binding head domains

Potent peptidic fusion inhibitors of influenza virus

Probing the antigenicity of hepatitis C virus envelope glycoprotein complex by high-throughput mutagenesis

Proof of concept for rational design of hepatitis C virus E2 core nanoparticle vaccines

Selection of a picomolar antibody that targets CXCR2-mediated neutrophil activation and alleviates EAE symptoms

Single-component multilayered self-assembling nanoparticles presenting rationally designed glycoprotein trimers as Ebola virus vaccines

Structural Biology of Influenza Hemagglutinin: An Amaranthine Adventure

Structural and biophysical correlation of anti-NANP antibodies with in vivo protection against P. falciparum

Structural basis of a shared antibody response to SARS-CoV-2

Structural basis of broad HIV neutralization by a vaccine-induced cow antibody

Structural insights of a highly potent pan-neutralizing SARS-CoV-2 human monoclonal antibody

Structure and immunogenicity of a stabilized HIV-1 envelope trimer based on a group-M consensus sequence

Structure and mechanism of monoclonal antibody binding to the junctional epitope of Plasmodium falciparum circumsporozoite protein

Structure of a cleavage-independent HIV Env recapitulates the glycoprotein architecture of the native cleaved trimer.

Structures of single-layer β-sheet proteins evolved from β-hairpin repeats

Synthetic development of a broadly neutralizing antibody against snake venom long-chain α-neurotoxins

The human naive B cell repertoire contains distinct subclasses for a germline-targeting HIV-1 vaccine immunogen

Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin

Vulnerabilities in coronavirus glycan shields despite extensive glycosylation