Lista de obras -

A C-terminal EGF-like domain governs BAD1 localization to the yeast surface and fungal adherence to phagocytes, but is dispensable in immune modulation and pathogenicity of Blastomyces dermatitidis

artículo científico publicado en 2003

A Large Community Outbreak of Blastomycosis in Wisconsin With Geographic and Ethnic Clustering ⬇️

artículo científico publicado el 3 de junio de 2013

A TCR Transgenic Mouse Reactive with Multiple Systemic Dimorphic Fungi ⬇️

artículo científico publicado el 24 de junio de 2011

Adaptive Immunity to Fungi ⬇️

artículo científico publicado el 3 de enero de 2012

Adaptive immunity to fungi.

artículo científico publicado en 2014

Agrobacterium tumefaciens integrates transfer DNA into single chromosomal sites of dimorphic fungi and yields homokaryotic progeny from multinucleate yeast

artículo científico publicado en 2002

An unappreciated role for neutrophil-DC hybrids in immunity to invasive fungal infections

artículo científico publicado en 2018

Analysis of non-adhesive pathogenic mechanisms of BAD1 on Blastomyces dermatitidis

artículo científico publicado en 2006

Antifungal Tc17 cells are durable and stable, persisting as long-lasting vaccine memory without plasticity towards IFNγ cells

artículo científico publicado en 2017

Antigen discovery unveils resident memory and migratory cell roles in antifungal resistance

artículo científico publicado en 2020

Aspergillus fumigatus Copper Export Machinery and Reactive Oxygen Intermediate Defense Counter Host Copper-Mediated Oxidative Antimicrobial Offense

artículo científico publicado en 2017

Aspergillus fumigatus Copper Export Machinery and Reactive Oxygen Intermediate Defense Counter Host Copper-Mediated Oxidative Antimicrobial Offense

artículo científico publicado en 2017

BAD1, an essential virulence factor of Blastomyces dermatitidis, suppresses host TNF-alpha production through TGF-beta-dependent and -independent mechanisms

scientific article published on 01 June 2002

Blastomyces dermatitidis serine protease dipeptidyl peptidase IVA (DppIVA) cleaves ELR+ CXC chemokines altering their effects on neutrophils.

artículo científico publicado en 2017

C-type lectin receptors differentially induce th17 cells and vaccine immunity to the endemic mycosis of North America

artículo científico publicado en 2014

CARD9-Associated Dectin-1 and Dectin-2 Are Required for Protective Immunity of a Multivalent Vaccine against Coccidioides posadasii Infection

artículo científico publicado en 2020

CBLB Constrains Inactivated Vaccine-Induced CD8+ T Cell Responses and Immunity against Lethal Fungal Pneumonia

artículo científico publicado en 2018

CD28 is required for optimal induction, but not maintenance, of vaccine-induced immunity to Blastomyces dermatitidis

artículo científico publicado en 2005

CRISPR/Cas9-Mediated Gene Disruption Reveals the Importance of Zinc Metabolism for Fitness of the Dimorphic Fungal Pathogen Blastomyces dermatitidis

artículo científico publicado en 2018

Calcium binding by the essential virulence factor BAD-1 of Blastomyces dermatitidis

artículo científico publicado en 2005

Calnexin induces expansion of antigen-specific CD4(+) T cells that confer immunity to fungal ascomycetes via conserved epitopes.

artículo científico publicado en 2015

Characterization of C-type lectins reveals an unexpectedly limited interaction between Cryptococcus neoformans spores and Dectin-1

artículo científico publicado en 2017

Chitin elicits CCL2 from airway epithelial cells and induces CCR2-dependent innate allergic inflammation in the lung

artículo científico publicado en 2012

Clinical Manifestations and Treatment of Blastomycosis

artículo científico publicado en 2017

Club Cell TRPV4 Serves as a Damage Sensor Driving Lung Allergic Inflammation

artículo científico publicado en 2020

Club cell TRPV4 as a damage sensor driving lung allergic inflammation

artículo científico publicado en 2019

Complement component 3C3 and C3a receptor are required in chitin-dependent allergic sensitization to Aspergillus fumigatus but dispensable in chitin-induced innate allergic inflammation

artículo científico publicado en 2013

Dectin-2 is a C-Type Lectin Receptor that Recognizes Pneumocystis and Participates in Innate Immune Responses

artículo científico publicado en 2017

Detection and measurement of two-component systems that control dimorphism and virulence in fungi

artículo científico publicado en 2007

Development of a highly sensitive and specific blastomycosis antibody enzyme immunoassay using Blastomyces dermatitidis surface protein BAD-1

artículo científico publicado en 2013

Differential requirements of T cell subsets for CD40 costimulation in immunity to Blastomyces dermatitidis

artículo científico publicado en 2006

Discordant influence of Blastomyces dermatitidis yeast-phase-specific gene BYS1 on morphogenesis and virulence

artículo científico publicado en 2010

Dynamic interplay among monocyte-derived, dermal, and resident lymph node dendritic cells during the generation of vaccine immunity to fungi

artículo científico publicado en 2010

Early immune response against Fonsecaea pedrosoi requires Dectin-2-mediated Th17 activity, whereas Th1 response, aided by Treg cells, is crucial for fungal clearance in later stage of experimental chromoblastomycosis

artículo científico publicado en 2020

Exploiting type 3 complement receptor for TNF-alpha suppression, immune evasion, and progressive pulmonary fungal infection

artículo científico publicado en 2004

Fonsecaea pedrosoi-induced Th17-cell differentiation in mice is fostered by Dectin-2 and suppressed by Mincle recognition

artículo científico publicado en 2015

Fungal Mimicry of a Mammalian Aminopeptidase Disables Innate Immunity and Promotes Pathogenicity

artículo científico publicado en 2016

Fungi subvert vaccine T cell priming at the respiratory mucosa by preventing chemokine-induced influx of inflammatory monocytes

artículo científico publicado en 2012

Gene Editing in Dimorphic Fungi Using CRISPR/Cas9

artículo científico publicado en 2020

Genetic diversity in Blastomyces dermatitidis: implications for PCR detection in clinical and environmental samples

artículo científico publicado en 2010

Global control of dimorphism and virulence in fungi

artículo científico publicado en 2006

Helper T-Cell Responses and Pulmonary Fungal Infections.

artículo científico publicado en 2018

IL-12 is required for induction but not maintenance of protective, memory responses to Blastomyces dermatitidis: implications for vaccine development in immune-deficient hosts

artículo científico publicado en 2005

Identification of the mating-type (MAT) locus that controls sexual reproduction of Blastomyces dermatitidis

artículo científico publicado en 2012

Indirect regulation of CD4 T-cell responses by tumor necrosis factor receptors in an acute viral infection.

artículo científico publicado en 2007

Infectious particle identity determines dissemination and disease outcome for the inhaled human fungal pathogen Cryptococcus

scientific article published on 27 June 2019

Inhaled Cryptococcus neoformans elicits allergic airway inflammation independent of Nuclear Factor Kappa B signalling in lung epithelial cells

artículo científico publicado en 2017

Interleukin 1 enhances vaccine-induced antifungal T-helper 17 cells and resistance against Blastomyces dermatitidis infection

artículo científico publicado en 2013

Interleukin-1 receptor but not Toll-like receptor 2 is essential for MyD88-dependent Th17 immunity to Coccidioides infection

artículo científico publicado en 2014

Intrinsic MyD88-Akt1-mTOR Signaling Coordinates Disparate Tc17 and Tc1 Responses during Vaccine Immunity against Fungal Pneumonia.

artículo científico publicado en 2015

Investigation of Genetic Susceptibility to Blastomycosis Reveals Interleukin-6 as a Potential Susceptibility Locus

scientific article published on 18 June 2019

Isolation of Blastomyces dermatitidis yeast from lung tissue during murine infection for in vivo transcriptional profiling

artículo científico publicado en 2013

Ligation of Dectin-2 with a novel microbial ligand promotes adjuvant activity for vaccination.

artículo científico publicado en 2017

Limited model antigen expression by transgenic fungi induces disparate fates during differentiation of adoptively transferred T cell receptor transgenic CD4+ T cells: robust activation and proliferation with weak effector function during recall.

artículo científico publicado en 2011

Linking fungal morphogenesis with virulence

artículo científico publicado en 2002

Lung Epithelial Cells Coordinate Innate Lymphocytes and Immunity against Pulmonary Fungal Infection

artículo científico publicado en 2018

Lung Epithelial Cells Coordinate Innate Lymphocytes and Immunity against Pulmonary Fungal Infection

scientific article published on 01 April 2019

Mannose Receptor Is Required for Optimal Induction of Vaccine-Induced T-Helper Type 17 Cells and Resistance to Blastomyces dermatitidis Infection

artículo científico publicado en 2016

Molecular genetic analysis of Blastomyces dermatitidis reveals new insights about pathogenic mechanisms

artículo científico publicado en 2002

MyD88 Shapes Vaccine Immunity by Extrinsically Regulating Survival of CD4+ T Cells during the Contraction Phase

artículo científico publicado en 2016

Non-Rural Point Source Blastomycosis Outbreak Near a Yard Waste Collection Site ⬇️

artículo científico publicado el 25 de octubre de 2010

Novel strategies to enhance vaccine immunity against coccidioidomycosis

artículo científico publicado en 2013

O-Mannosylation of Proteins Enables Histoplasma Yeast Survival at Mammalian Body Temperatures

artículo científico publicado en 2018

Progress in vaccination for histoplasmosis and blastomycosis: coping with cellular immunity

artículo científico publicado en 2005

Protective antifungal memory CD8+ T cells are maintained in the absence of CD4+ T cell help and cognate antigen in mice ⬇️

artículo científico publicado el 22 de febrero de 2012

Pulmonary neuroendocrine cells amplify allergic asthma responses

artículo científico publicado en 2018

Requisite elements in vaccine immunity to Blastomyces dermatitidis: plasticity uncovers vaccine potential in immune-deficient hosts

artículo científico publicado en 2002

SREB, a GATA transcription factor that directs disparate fates in Blastomyces dermatitidis including morphogenesis and siderophore biosynthesis

artículo científico publicado en 2010

Safety, tolerability, and immunogenicity of a recombinant, genetically engineered, live-attenuated vaccine against canine blastomycosis

artículo científico publicado en 2011

Spleen Tyrosine Kinase Is a Critical Regulator of Neutrophil Responses to Candida Species

artículo científico publicado en 2020

Structural basis of Blastomyces Endoglucanase-2 adjuvancy in anti-fungal and -viral immunity

artículo científico publicado en 2021

Structure and function of a fungal adhesin that binds heparin and mimics thrombospondin-1 by blocking T cell activation and effector function.

artículo científico publicado en 2013

T cell receptor cross-reactivity between similar foreign and self peptides influences naive cell population size and autoimmunity

artículo científico publicado en 2015

Tc17 Cells Mediate Vaccine Immunity against Lethal Fungal Pneumonia in Immune Deficient Hosts Lacking CD4+ T Cells ⬇️

artículo científico publicado el 19 de julio de 2012

The C-Type Lectin Receptor MCL Mediates Vaccine-Induced Immunity against Infection with Blastomyces dermatitidis.

artículo científico publicado en 2015

The Dynamic Genome and Transcriptome of the Human Fungal Pathogen Blastomyces and Close Relative Emmonsia

artículo científico publicado en 2015

The Eng1 β-Glucanase Enhances Histoplasma Virulence by Reducing β-Glucan Exposure

artículo científico publicado en 2016

The Interaction of Pneumocystis with the C-Type Lectin Receptor Mincle Exerts a Significant Role in Host Defense against Infection

artículo científico publicado en 2017

The unappreciated intracellular lifestyle of Blastomyces dermatitidis

artículo científico publicado en 2015

Threats Posed by the Fungal Kingdom to Humans, Wildlife, and Agriculture

scientific article published on 05 May 2020

Through the Scope Darkly: The Gut Mycobiome Comes into Focus

artículo científico publicado en 2017

Transcription Factor KLF2 in Dendritic Cells Downregulates Th2 Programming via the HIF-1α/Jagged2/Notch Axis

artículo científico publicado en 2016

Turning on Virulence: Mechanisms that underpin the Morphologic Transition and Pathogenicity of Blastomyces.

artículo científico publicado en 2018

Using new genetic tools to study the pathogenesis of Blastomyces dermatitidis ⬇️

artículo científico publicado el 1 de enero de 2002

V beta1+ J beta1.1+/V alpha2+ J alpha49+ CD4+ T cells mediate resistance against infection with Blastomyces dermatitidis

artículo científico publicado en 2006

Vaccine Immunity to Coccidioidomycosis Occurs by Early Activation of Three Signal Pathways of T Helper Cell Response (Th1, Th2, and Th17) ⬇️

artículo científico publicado el 22 de agosto de 2011

Vaccine immunity against fungal infections

artículo científico publicado en 2014

Vaccine immunity to pathogenic fungi overcomes the requirement for CD4 help in exogenous antigen presentation to CD8+ T cells: implications for vaccine development in immune-deficient hosts

artículo científico publicado en 2003

Vaccine-induced protection against 3 systemic mycoses endemic to North America requires Th17 cells in mice

artículo científico publicado en 2016

Vaccine-induced protection against 3 systemic mycoses endemic to North America requires Th17 cells in mice.

artículo científico publicado en 2011

Virally-vectored vaccine candidates against white-nose syndrome induce anti-fungal immune response in little brown bats (Myotis lucifugus)

artículo científico publicado en 2019

Lista de obras de

A C-terminal EGF-like domain governs BAD1 localization to the yeast surface and fungal adherence to phagocytes, but is dispensable in immune modulation and pathogenicity of Blastomyces dermatitidis

A Large Community Outbreak of Blastomycosis in Wisconsin With Geographic and Ethnic Clustering ⬇️

A TCR Transgenic Mouse Reactive with Multiple Systemic Dimorphic Fungi ⬇️

Adaptive Immunity to Fungi ⬇️

Adaptive immunity to fungi.

Agrobacterium tumefaciens integrates transfer DNA into single chromosomal sites of dimorphic fungi and yields homokaryotic progeny from multinucleate yeast

An unappreciated role for neutrophil-DC hybrids in immunity to invasive fungal infections

Analysis of non-adhesive pathogenic mechanisms of BAD1 on Blastomyces dermatitidis

Antifungal Tc17 cells are durable and stable, persisting as long-lasting vaccine memory without plasticity towards IFNγ cells

Antigen discovery unveils resident memory and migratory cell roles in antifungal resistance

Aspergillus fumigatus Copper Export Machinery and Reactive Oxygen Intermediate Defense Counter Host Copper-Mediated Oxidative Antimicrobial Offense

Aspergillus fumigatus Copper Export Machinery and Reactive Oxygen Intermediate Defense Counter Host Copper-Mediated Oxidative Antimicrobial Offense

BAD1, an essential virulence factor of Blastomyces dermatitidis, suppresses host TNF-alpha production through TGF-beta-dependent and -independent mechanisms

Blastomyces dermatitidis serine protease dipeptidyl peptidase IVA (DppIVA) cleaves ELR+ CXC chemokines altering their effects on neutrophils.

C-type lectin receptors differentially induce th17 cells and vaccine immunity to the endemic mycosis of North America

CARD9-Associated Dectin-1 and Dectin-2 Are Required for Protective Immunity of a Multivalent Vaccine against Coccidioides posadasii Infection

CBLB Constrains Inactivated Vaccine-Induced CD8+ T Cell Responses and Immunity against Lethal Fungal Pneumonia

CD28 is required for optimal induction, but not maintenance, of vaccine-induced immunity to Blastomyces dermatitidis

CRISPR/Cas9-Mediated Gene Disruption Reveals the Importance of Zinc Metabolism for Fitness of the Dimorphic Fungal Pathogen Blastomyces dermatitidis

Calcium binding by the essential virulence factor BAD-1 of Blastomyces dermatitidis

Calnexin induces expansion of antigen-specific CD4(+) T cells that confer immunity to fungal ascomycetes via conserved epitopes.

Characterization of C-type lectins reveals an unexpectedly limited interaction between Cryptococcus neoformans spores and Dectin-1

Chitin elicits CCL2 from airway epithelial cells and induces CCR2-dependent innate allergic inflammation in the lung

Clinical Manifestations and Treatment of Blastomycosis

Club Cell TRPV4 Serves as a Damage Sensor Driving Lung Allergic Inflammation

Club cell TRPV4 as a damage sensor driving lung allergic inflammation

Complement component 3C3 and C3a receptor are required in chitin-dependent allergic sensitization to Aspergillus fumigatus but dispensable in chitin-induced innate allergic inflammation

Dectin-2 is a C-Type Lectin Receptor that Recognizes Pneumocystis and Participates in Innate Immune Responses

Detection and measurement of two-component systems that control dimorphism and virulence in fungi

Development of a highly sensitive and specific blastomycosis antibody enzyme immunoassay using Blastomyces dermatitidis surface protein BAD-1

Differential requirements of T cell subsets for CD40 costimulation in immunity to Blastomyces dermatitidis

Discordant influence of Blastomyces dermatitidis yeast-phase-specific gene BYS1 on morphogenesis and virulence

Dynamic interplay among monocyte-derived, dermal, and resident lymph node dendritic cells during the generation of vaccine immunity to fungi

Early immune response against Fonsecaea pedrosoi requires Dectin-2-mediated Th17 activity, whereas Th1 response, aided by Treg cells, is crucial for fungal clearance in later stage of experimental chromoblastomycosis

Exploiting type 3 complement receptor for TNF-alpha suppression, immune evasion, and progressive pulmonary fungal infection

Fonsecaea pedrosoi-induced Th17-cell differentiation in mice is fostered by Dectin-2 and suppressed by Mincle recognition

Fungal Mimicry of a Mammalian Aminopeptidase Disables Innate Immunity and Promotes Pathogenicity

Fungi subvert vaccine T cell priming at the respiratory mucosa by preventing chemokine-induced influx of inflammatory monocytes

Gene Editing in Dimorphic Fungi Using CRISPR/Cas9

Genetic diversity in Blastomyces dermatitidis: implications for PCR detection in clinical and environmental samples

Global control of dimorphism and virulence in fungi

Helper T-Cell Responses and Pulmonary Fungal Infections.

IL-12 is required for induction but not maintenance of protective, memory responses to Blastomyces dermatitidis: implications for vaccine development in immune-deficient hosts

Identification of the mating-type (MAT) locus that controls sexual reproduction of Blastomyces dermatitidis

Indirect regulation of CD4 T-cell responses by tumor necrosis factor receptors in an acute viral infection.

Infectious particle identity determines dissemination and disease outcome for the inhaled human fungal pathogen Cryptococcus

Inhaled Cryptococcus neoformans elicits allergic airway inflammation independent of Nuclear Factor Kappa B signalling in lung epithelial cells

Interleukin 1 enhances vaccine-induced antifungal T-helper 17 cells and resistance against Blastomyces dermatitidis infection

Interleukin-1 receptor but not Toll-like receptor 2 is essential for MyD88-dependent Th17 immunity to Coccidioides infection

Intrinsic MyD88-Akt1-mTOR Signaling Coordinates Disparate Tc17 and Tc1 Responses during Vaccine Immunity against Fungal Pneumonia.

Investigation of Genetic Susceptibility to Blastomycosis Reveals Interleukin-6 as a Potential Susceptibility Locus

Isolation of Blastomyces dermatitidis yeast from lung tissue during murine infection for in vivo transcriptional profiling

Ligation of Dectin-2 with a novel microbial ligand promotes adjuvant activity for vaccination.

Limited model antigen expression by transgenic fungi induces disparate fates during differentiation of adoptively transferred T cell receptor transgenic CD4+ T cells: robust activation and proliferation with weak effector function during recall.

Linking fungal morphogenesis with virulence

Lung Epithelial Cells Coordinate Innate Lymphocytes and Immunity against Pulmonary Fungal Infection

Lung Epithelial Cells Coordinate Innate Lymphocytes and Immunity against Pulmonary Fungal Infection

Mannose Receptor Is Required for Optimal Induction of Vaccine-Induced T-Helper Type 17 Cells and Resistance to Blastomyces dermatitidis Infection

Molecular genetic analysis of Blastomyces dermatitidis reveals new insights about pathogenic mechanisms

MyD88 Shapes Vaccine Immunity by Extrinsically Regulating Survival of CD4+ T Cells during the Contraction Phase

Non-Rural Point Source Blastomycosis Outbreak Near a Yard Waste Collection Site ⬇️

Novel strategies to enhance vaccine immunity against coccidioidomycosis

O-Mannosylation of Proteins Enables Histoplasma Yeast Survival at Mammalian Body Temperatures

Progress in vaccination for histoplasmosis and blastomycosis: coping with cellular immunity

Protective antifungal memory CD8+ T cells are maintained in the absence of CD4+ T cell help and cognate antigen in mice ⬇️

Pulmonary neuroendocrine cells amplify allergic asthma responses

Requisite elements in vaccine immunity to Blastomyces dermatitidis: plasticity uncovers vaccine potential in immune-deficient hosts

SREB, a GATA transcription factor that directs disparate fates in Blastomyces dermatitidis including morphogenesis and siderophore biosynthesis

Safety, tolerability, and immunogenicity of a recombinant, genetically engineered, live-attenuated vaccine against canine blastomycosis

Spleen Tyrosine Kinase Is a Critical Regulator of Neutrophil Responses to Candida Species

Structural basis of Blastomyces Endoglucanase-2 adjuvancy in anti-fungal and -viral immunity

Structure and function of a fungal adhesin that binds heparin and mimics thrombospondin-1 by blocking T cell activation and effector function.

T cell receptor cross-reactivity between similar foreign and self peptides influences naive cell population size and autoimmunity

Tc17 Cells Mediate Vaccine Immunity against Lethal Fungal Pneumonia in Immune Deficient Hosts Lacking CD4+ T Cells ⬇️

The C-Type Lectin Receptor MCL Mediates Vaccine-Induced Immunity against Infection with Blastomyces dermatitidis.

The Dynamic Genome and Transcriptome of the Human Fungal Pathogen Blastomyces and Close Relative Emmonsia

The Eng1 β-Glucanase Enhances Histoplasma Virulence by Reducing β-Glucan Exposure

The Interaction of Pneumocystis with the C-Type Lectin Receptor Mincle Exerts a Significant Role in Host Defense against Infection

The unappreciated intracellular lifestyle of Blastomyces dermatitidis