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A chemical probe based on the PreQ<sub>1</sub> metabolite enables transcriptome-wide mapping of binding sites

scientific article published on 06 October 2021

Chemical Modulation of Pre-mRNA Splicing in Mammalian Systems

scientific article published on 07 April 2020

Chemical and structural studies provide a mechanistic basis for recognition of the MYC G-quadruplex

artículo científico publicado en 2018

Custom DNA Microarrays Reveal Diverse Binding Preferences of Proteins and Small Molecules to Thousands of G-Quadruplexes

scientific article published on 07 April 2020

Discovery of Inhibitors of MicroRNA-21 Processing Using Small Molecule Microarrays.

artículo científico

Dynamic bulge nucleotides in the KSHV PAN ENE triple helix provide a unique binding platform for small molecule ligands

artículo científico publicado en 2021

Evidence for ligandable sites in structured RNA throughout the Protein Data Bank

scientific article published on 06 April 2019

Insights Into the Allosteric Inhibition of the SUMO E2 Enzyme Ubc9

Insights Into the Allosteric Inhibition of the SUMO E2 Enzyme Ubc9.

artículo científico publicado en 2016

Macrophilone A: Structure Elucidation, Total Synthesis, and Functional Evaluation of a Biologically Active Iminoquinone from the Marine Hydroid Macrorhynchia philippina

artículo científico publicado en 2017

Macrophilones from the Marine Hydroid Macrorhynchia philippina Can Inhibit ERK Cascade Signaling.

artículo científico publicado en 2018

Measuring RNA-Ligand Interactions with Microscale Thermophoresis.

artículo científico publicado en 2018

Probing the hras-1Y i-motif with small molecules

scientific article published on 05 October 2018

Selective Small-Molecule Targeting of a Triple Helix Encoded by the Long Noncoding RNA, MALAT1

artículo científico publicado en 2019

Synthetic ligands for PreQ riboswitches provide structural and mechanistic insights into targeting RNA tertiary structure

artículo científico publicado en 2019

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