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Antiangiogenic Activity and in Silico Cereblon Binding Analysis of Novel Thalidomide Analogs

scientific article published on 02 December 2020

Conformational energy range of ligands in protein crystal structures: The difficult quest for accurate understanding

artículo científico publicado en 2017

Diacylglycerol lactones targeting the structural features that distinguish the atypical C1 domains of protein kinase C ζ and ι from typical C1 domains

artículo científico publicado en 2014

Epigenetic re-wiring of breast cancer by pharmacological targeting of C-terminal binding protein

scientific article published on 18 September 2019

Experimental and Chemoinformatics Study of Tautomerism in a Database of Commercially Available Screening Samples

artículo científico publicado en 2016

Exploring the influence of indololactone structure on selectivity for binding to the C1 domains of PKCα, PKCε, and RasGRP.

artículo científico publicado en 2017

Macrophilone A: Structure Elucidation, Total Synthesis, and Functional Evaluation of a Biologically Active Iminoquinone from the Marine Hydroid Macrorhynchia philippina

artículo científico publicado en 2017

Molecular Modeling of the Bacterial Chemotaxis Receptors Tar and Trg

doctoral thesis by Megan L. Peach, University of Washington, 2001

Probing the hras-1Y i-motif with small molecules

scientific article published on 05 October 2018

QSAR modeling of imbalanced high-throughput screening data in PubChem

artículo científico publicado en 2014

SAVI, in silico generation of billions of easily synthesizable compounds through expert-system type rules

artículo científico publicado en 2020

Structural Basis for the Failure of the C1 Domain of Ras Guanine Nucleotide Releasing Protein 2 (RasGRP2) to Bind Phorbol Ester with High Affinity

artículo científico publicado en 2016

Synthesis and Biological Evaluation of Several Bryostatin Analogues Bearing a Diacylglycerol Lactone C-Ring.

artículo científico publicado en 2016

Synthesis of a des-B-ring bryostatin analogue leads to an unexpected ring expansion of the bryolactone core

artículo científico publicado en 2014

Synthesis, biological, and biophysical studies of DAG-indololactones designed as selective activators of RasGRP.

artículo científico publicado en 2014

Synthetic derivatives of the SUMO consensus sequence provide a basis for improved substrate recognition.

artículo científico publicado en 2015

Therapeutic Antibodies to Ganglioside GD2 Evolved from Highly Selective Germline Antibodies.

artículo científico publicado en 2017

α-Arylidene Diacylglycerol-Lactones (DAG-Lactones) as Selective Ras Guanine Releasing Protein 3 (RasGRP3) Ligands.

artículo científico publicado en 2018