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1,1-Bis (3'-indolyl)-1-(p-substitutedphenyl)methane compounds inhibit lung cancer cell and tumor growth in a metastasis model

artículo científico publicado en 2013

1,1-Bis(3'-indolyl)-1-(p-biphenyl)methane inhibits basal-like breast cancer growth in athymic nude mice

artículo científico publicado en 2007

1,1-Bis(3'-indolyl)-1-(p-bromophenyl)methane and related compounds repress survivin and decrease gamma-radiation-induced survivin in colon and pancreatic cancer cells

artículo científico publicado en 2009

1,1-Bis(3'-indolyl)-1-(p-chlorophenyl)methane activates the orphan nuclear receptor Nurr1 and inhibits bladder cancer growth

artículo científico publicado en 2008

1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes induce autophagic cell death in estrogen receptor negative breast cancer ⬇️

artículo científico publicado el 3 de diciembre de 2010

1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes inhibit colon cancer cell and tumor growth through PPARgamma-dependent and PPARgamma-independent pathways

artículo científico publicado en 2006

1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes inhibit colon cancer cell and tumor growth through activation of c-jun N-terminal kinase

artículo científico publicado en 2008

1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes inhibit ovarian cancer cell growth through peroxisome proliferator-activated receptor-dependent and independent pathways

artículo científico publicado en 2006

1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes inhibit proliferation of estrogen receptor-negative breast cancer cells by activation of multiple pathways.

artículo científico publicado en 2007

1,1-Bis(3'-indolyl)-1-(p-substitutedphenyl)methanes are peroxisome proliferator-activated receptor gamma agonists but decrease HCT-116 colon cancer cell survival through receptor-independent activation of early growth response-1 and nonsteroidal ant

artículo científico publicado en 2005

1,1-Bis(3'-indolyl)-1-(p-substitutedphenyl)methanes induce peroxisome proliferator-activated receptor gamma-mediated growth inhibition, transactivation, and differentiation markers in colon cancer cells

artículo científico publicado en 2004

1,1-bis(3'-indolyl)-1-(p-methoxyphenyl)methane activates Nur77-independent proapoptotic responses in colon cancer cells

artículo científico publicado en 2008

1,1-bis(3'-indolyl)-1-(p-substituted phenyl)methanes decrease mitochondrial membrane potential and induce apoptosis in endometrial and other cancer cell lines ⬇️

scientific article published on July 2008

1,1-bis(3'-indolyl)-1-(p-substitutedphenyl)methanes induce apoptosis and inhibit renal cell carcinoma growth

artículo científico publicado en 2007

1,1-bis(3'-indolyl)-1-(p-substitutedphenyl)methanes inhibit growth, induce apoptosis, and decrease the androgen receptor in LNCaP prostate cancer cells through peroxisome proliferator-activated receptor gamma-independent pathways

artículo científico publicado en 2006

17 beta-Estradiol-mediated growth inhibition of MDA-MB-468 cells stably transfected with the estrogen receptor: cell cycle effects

scientific article published on 01 September 1997

2,2',4,4',5,5'-hexachlorobiphenyl as a 2,3,7,8-tetrachlorodibenzo-p-dioxin antagonist in C57BL/6J mice

artículo científico publicado en 1989

2,3,4,4'-Pentachlorobiphenyl: differential effects on C57BL/6J and DBA/2J inbred mice

scientific article published on 01 September 1982

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and Related Compounds as Antioestrogens: Characterization and Mechanism of Action ⬇️

artículo científico publicado el 1 de diciembre de 1991

2,3,7,8-Tetrachlorodibenzo-p-dioxin and diindolylmethanes differentially induce cytochrome P450 1A1, 1B1, and 19 in H295R human adrenocortical carcinoma cells.

artículo científico publicado en 2001

2-Cyano-3,12-dioxoolean-1,9-dien-28-oic acid and related compounds inhibit growth of colon cancer cells through peroxisome proliferator-activated receptor gamma-dependent and -independent pathways

artículo científico publicado en 2005

2-Cyano-3,12-dioxooleana-1,9-dien-28-imidazolide (CDDO-Im) directly targets mitochondrial glutathione to induce apoptosis in pancreatic cancer

artículo científico publicado en 2005

2-cyano-lup-1-en-3-oxo-20-oic acid, a cyano derivative of betulinic acid, activates peroxisome proliferator-activated receptor gamma in colon and pancreatic cancer cells

artículo científico publicado en 2007

3,3'-Diindolylmethane (DIM) and its ring-substituted halogenated analogs (ring-DIMs) induce differential mechanisms of survival and death in androgen-dependent and -independent prostate cancer cells.

artículo científico publicado en 2015

3,3'-diindolylmethane (DIM) and its derivatives induce apoptosis in pancreatic cancer cells through endoplasmic reticulum stress-dependent upregulation of DR5.

artículo científico publicado en 2005

3-Methylcholanthrene and other aryl hydrocarbon receptor agonists directly activate estrogen receptor alpha

artículo científico publicado en 2006

5,5'-Dibromo-bis(3'-indolyl)methane induces Kruppel-like factor 4 and p21 in colon cancer cells

artículo científico publicado en 2008

6-Methyl-1,3,8-trichlorodibenzofuran (MCDF) as a 2,3,7,8-tetrachlorodibenzo-p-dioxin antagonist in C57BL/6 mice

artículo científico publicado en 1989

6-Methyl-1,3,8-trichlorodibenzofuran (MCDF) as an antiestrogen in human and rodent cancer cell lines: evidence for the role of the Ah receptor

artículo científico publicado el 1 de abril de 1992

6-Methyl-1,3,8-trichlorodibenzofuran as a 2,3,7,8-tetrachlorodibenzo-p-dioxin antagonist: inhibition of the induction of rat cytochrome P-450 isozymes and related monooxygenase activities

scientific article published on 01 February 1988

7-Methyl-7-hexadecenoic acid: Isolation from lipids of the ocean sunfishMola mola (Linnaeus) 1758 ⬇️

artículo científico publicado el 1 de enero de 1973

732 A novel nuclear receptor 4A1 (NR4A1) antagonists attenuates T-cell exhaustion in colorectal cancer

artículo científico publicado en 2021

A Bis-Indole-Derived NR4A1 Antagonist Induces PD-L1 Degradation and Enhances Antitumor Immunity

scientific article published on 07 January 2020

A bioassay to measure energy metabolism in mouse colonic crypts, organoids, and sorted stem cells

artículo científico publicado en 2015

A comparison of the mouse versus human aryl hydrocarbon (Ah) receptor complex: effects of proteolysis

artículo científico publicado el 30 de noviembre de 1992

A general method for the preparation of tritiated polychlorobiphenyls of high specific activity: 2,2',5,5'-tetrachlorobiphenyl-(3H) and 2,2',4,4',5,5'-hexachlorobiphenyl-(3H).

artículo científico publicado en 1972

A new class of peroxisome proliferator-activated receptor gamma (PPARgamma) agonists that inhibit growth of breast cancer cells: 1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes.

artículo científico publicado en 2004

A novel diindolylmethane analog, 1,1-bis(3'-indolyl)-1-(p-chlorophenyl) methane, inhibits the tumor necrosis factor-induced inflammatory response in primary murine synovial fibroblasts through a Nurr1-dependent mechanism

artículo científico publicado en 2018

A novel regulator of macrophage activation: miR-223 in obesity-associated adipose tissue inflammation

artículo científico publicado en 2012

A novel ring-substituted diindolylmethane,1,1-bis[3'-(5-methoxyindolyl)]-1-(p-t-butylphenyl) methane, inhibits extracellular signal-regulated kinase activation and induces apoptosis in acute myelogenous leukemia

artículo científico publicado en 2005

A novel synthetic activator of Nurr1 induces dopaminergic gene expression and protects against 6-hydroxydopamine neurotoxicity in vitro

artículo científico publicado en 2015

Absorption and biological activity of phytochemical-rich extracts from açai (Euterpe oleracea Mart.) pulp and oil in vitro

artículo científico publicado en 2008

Abstract 154: Inhibition of pancreatic cancer Panc-1 cell migration by omeprazole is dependent on aryl hydrocarbon receptor activation of JNK

scholarly article

Abstract 1714: Nuclear receptor Nurr1 facilitates pancreatic ductal adenocarcinoma cell survival under metabolic stress

scholarly article

Activation of COUP-TFI by a Novel Diindolylmethane Derivative

scientific article published on 07 March 2019

Activation of Nur77 by selected 1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes induces apoptosis through nuclear pathways

artículo científico publicado en 2005

Activation of kinase pathways in MCF-7 cells by 17beta-estradiol and structurally diverse estrogenic compounds

artículo científico publicado en 2006

Activation of nerve growth factor-induced B alpha by methylene-substituted diindolylmethanes in bladder cancer cells induces apoptosis and inhibits tumor growth

artículo científico publicado en 2009

Activation of nuclear TR3 (NR4A1) by a diindolylmethane analog induces apoptosis and proapoptotic genes in pancreatic cancer cells and tumors

artículo científico publicado en 2011

Ah receptor ligands and their impacts on gut resilience: structure-activity effects

artículo científico publicado en 2020

Alteration of oxytocin-induced calcium oscillations in clone 9 cells by toxin exposure

artículo científico publicado en 1996

Analysis of estrogen receptor alpha-Sp1 interactions in breast cancer cells by fluorescence resonance energy transfer

artículo científico publicado en 2005

Anthocyanin fraction from potato extracts is cytotoxic to prostate cancer cells through activation of caspase-dependent and caspase-independent pathways.

artículo científico publicado en 2007

Antiandrogenic and growth inhibitory effects of ring-substituted analogs of 3,3'-diindolylmethane (ring-DIMs) in hormone-responsive LNCaP human prostate cancer cells.

artículo científico publicado en 2011

Antiestrogenic activity of hydroxylated polychlorinated biphenyl congeners identified in human serum

artículo científico publicado en 1997

Applications of the in vitro aryl hydrocarbon hydroxylase induction assay for determining "2,3,7,8-tetrachlorodibenzo-p-dioxin equivalents": pyrolyzed brominated flame retardants

artículo científico publicado en 1988

Aroclor 1254 as a 2,3,7,8-tetrachlorodibenzo-p-dioxin antagonist: effects on enzyme induction and immunotoxicity

artículo científico publicado en 1987

Arsenic trioxide downregulates specificity protein (Sp) transcription factors and inhibits bladder cancer cell and tumor growth

artículo científico publicado en 2010

Aryl Hydrocarbon Receptor (AHR) Ligands as Selective AHR Modulators (SAhRMs)

scientific article published on 11 September 2020

Aryl Hydrocarbon Receptor (AhR) Ligands as Selective AhR Modulators: Genomic Studies

artículo científico publicado en 2018

Aryl Hydrocarbon Receptor Activity of Tryptophan Metabolites in Young Adult Mouse Colonocytes

artículo científico publicado en 2015

Aryl hydrocarbon receptor (AHR)-active pharmaceuticals are selective AHR modulators in MDA-MB-468 and BT474 breast cancer cells

artículo científico publicado en 2012

Aryl hydrocarbon receptor agonists directly activate estrogen receptor alpha in MCF-7 breast cancer cells.

artículo científico publicado en 2006

Aryl hydrocarbon receptor agonists induce microRNA-335 expression and inhibit lung metastasis of estrogen receptor negative breast cancer cells.

artículo científico publicado en 2011

Aryl hydrocarbon receptor gene silencing with small inhibitory RNA differentially modulates Ah-responsiveness in MCF-7 and HepG2 cancer cells.

artículo científico publicado en 2003

Aryl hydrocarbon receptor-mediated inhibition of LNCaP prostate cancer cell growth and hormone-induced transactivation.

artículo científico publicado en 2004

Aspirin inhibits colon cancer cell and tumor growth and downregulates specificity protein (Sp) transcription factors

artículo científico publicado en 2012

Autophagy inhibition improves the chemotherapeutic efficacy of cruciferous vegetable-derived diindolymethane in a murine prostate cancer xenograft model

artículo científico publicado en 2018

Bardoxolone Methyl and a Related Triterpenoid Downregulate cMyc Expression in Leukemia Cells.

artículo científico publicado en 2017

Benzyl Isothiocyanate (BITC) Induces Reactive Oxygen Species-dependent Repression of STAT3 Protein by Down-regulation of Specificity Proteins in Pancreatic Cancer

artículo científico publicado en 2016

Betulinic acid decreases ER-negative breast cancer cell growth in vitro and in vivo: role of Sp transcription factors and microRNA-27a:ZBTB10

artículo científico publicado en 2012

Betulinic acid inhibits colon cancer cell and tumor growth and induces proteasome-dependent and -independent downregulation of specificity proteins (Sp) transcription factors

artículo científico publicado en 2011

Betulinic acid inhibits prostate cancer growth through inhibition of specificity protein transcription factors

artículo científico publicado en 2007

Betulinic acid targets YY1 and ErbB2 through cannabinoid receptor-dependent disruption of microRNA-27a:ZBTB10 in breast cancer

artículo científico publicado en 2012

Binding of polychlorinated biphenyls classified as either phenobarbitone-, 3-methylcholanthrene- or mixed-type inducers to cytosolic Ah receptor

scientific article published on 01 April 1982

Bis-Indole-Derived NR4A1 Ligands and Metformin Exhibit NR4A1-Dependent Glucose Metabolism and Uptake in C2C12 Cells

artículo científico publicado en 2018

Bis-Indole-Derived Nuclear Receptor 4A1 (NR4A1, Nur77) Ligands as Inhibitors of Endometriosis

artículo científico publicado en 2020

Bis-indole derived nuclear receptor 4A1 (NR4A1) antagonists inhibit TGFβ-induced invasion of embryonal rhabdomyosarcoma cells

scientific article published on 01 August 2020

Bisphenol A interacts with the estrogen receptor alpha in a distinct manner from estradiol

artículo científico publicado en 1998

Bortezomib Targets Sp Transcription Factors in Cancer Cells

scientific article published on 16 August 2018

CDODA-Me decreases specificity protein transcription factors and induces apoptosis in bladder cancer cells through induction of reactive oxygen species

artículo científico publicado en 2016

Cancer chemotherapy with indole-3-carbinol, bis(3'-indolyl)methane and synthetic analogs

artículo científico publicado en 2008

Celastrol decreases specificity proteins (Sp) and fibroblast growth factor receptor-3 (FGFR3) in bladder cancer cells ⬇️

artículo científico publicado el 14 de febrero de 2012

Characterization and Biological Potency of Mono- to Tetra-Halogenated Carbazoles

artículo científico publicado en 2015

Characterization of calcium oscillations in normal and benzo[a]pyrene-treated clone 9 cells

artículo científico publicado en 2002

Characterization of the aryl hydrocarbon receptor in the human C-4II cervical squamous carcinoma cell line ⬇️

artículo científico publicado el 1 de abril de 1992

Chemoprevention of skin cancer with 1,1-Bis (3'-indolyl)-1-(aromatic) methane analog through induction of the orphan nuclear receptor, NR4A2 (Nurr1)

artículo científico publicado en 2013

Chemopreventive effects of synthetic C-substituted diindolylmethanes originating from cruciferous vegetables in human oral cancer cells

artículo científico publicado en 2011

Chemopreventive effects of tolfenamic acid against esophageal tumorigenesis in rats.

artículo científico publicado en 2011

Chlorobiphenylols. Thin-layer chromatography and colour reactions of some hydroxylated chlorobiphenyls

artículo científico publicado en 1974

Cobaltous chloride and hypoxia inhibit aryl hydrocarbon receptor-mediated responses in breast cancer cells

artículo científico publicado en 2007

Comparative activities of 2,3,7,8-tetrachlorodibenzo-p-dioxin and progesterone as antiestrogens in the female rat uterus

scientific article published on 01 March 1988

Comparative estrogenic activity of wine extracts and organochlorine pesticide residues in food

artículo científico publicado en 1998

Comparative in vitro and in vivo genotoxicities of 7H-benzo[c]fluorene, manufactured gas plant residue (MGP), and MGP fractions

artículo científico publicado en 2004

Comparative potencies of Aroclors 1232, 1242, 1248, 1254, and 1260 in male Wistar rats--assessment of the toxic equivalency factor (TEF) approach for polychlorinated biphenyls (PCBs)

scientific article published on 01 May 1993

Compensatory Expression of Nur77 and Nurr1 Regulates NF-B-Dependent Inflammatory Signaling in Astrocytes

scholarly article by Katriana A Popichak et al published October 2018 in Molecular Pharmacology

Competitive binding of 7-substituted-2,3-dichlorodibenzo-p-dioxins with human placental ah receptor--a QSAR analysis

artículo científico publicado en 1990

Competitive binding to the cytosolic 2,3,7,8-tetrachlorodibenzo-p-dioxin receptor. Effects of structure on the affinities of substituted halogenated biphenyls--a QSAR analysis

artículo científico publicado en 1983

Conjugated linoleic acid stimulates an anti-tumorigenic protein NAG-1 in an isomer specific manner

artículo científico publicado en 2005

Cooperative coactivation of estrogen receptor alpha in ZR-75 human breast cancer cells by SNURF and TATA-binding protein

artículo científico publicado en 2001

Correction for Hedrick et al., "NR4A1 Antagonists Inhibit β1-Integrin-Dependent Breast Cancer Cell Migration".

artículo científico publicado en 2017

Curcumin and synthetic analogs induce reactive oxygen species and decreases specificity protein (Sp) transcription factors by targeting microRNAs

artículo científico publicado en 2012

Curcumin decreases specificity protein expression in bladder cancer cells

artículo científico publicado en 2008

Cyclooxygenase-2 inhibitors decrease vascular endothelial growth factor expression in colon cancer cells by enhanced degradation of Sp1 and Sp4 proteins

artículo científico publicado en 2005

Cytochrome P-450-mediated metabolism of biphenyl and the 4-halobiphenyls

artículo científico publicado en 1982

Cytotoxicity of pomegranate polyphenolics in breast cancer cells in vitro and vivo: potential role of miRNA-27a and miRNA-155 in cell survival and inflammation

artículo científico publicado en 2012

DNA binding properties of the Ah receptor in wild-type and variant mouse hepatoma cells

artículo científico publicado en 1991

DRIP150 coactivation of estrogen receptor alpha in ZR-75 breast cancer cells is independent of LXXLL motifs

artículo científico publicado en 2004

Development and validation of bioassays for polychlorinated dibenzo-p-dioxins and dibenzofurans

artículo científico publicado el 1 de enero de 1991

Development and validation of in vitro induction assays for toxic halogenated aromatic mixtures: a review

artículo científico publicado en 1989

Differential activation of wild-type estrogen receptor alpha and C-terminal deletion mutants by estrogens, antiestrogens and xenoestrogens in breast cancer cells

artículo científico publicado en 2007

Differential gene expression in response to methoxychlor and estradiol through ERalpha, ERbeta, and AR in reproductive tissues of female mice.

artículo científico

Differential interaction of the methoxychlor metabolite 2,2-bis-(p-hydroxyphenyl)-1,1,1-trichloroethane with estrogen receptors alpha and beta

artículo científico publicado en 1999

Diindolylmethane analogs bind NR4A1 and are NR4A1 antagonists in colon cancer cells

artículo científico publicado en 2014

Diindolylmethane and its halogenated derivatives induce protective autophagy in human prostate cancer cells via induction of the oncogenic protein AEG-1 and activation of AMP-activated protein kinase (AMPK).

artículo científico publicado en 2017

Domains of estrogen receptor alpha (ERalpha) required for ERalpha/Sp1-mediated activation of GC-rich promoters by estrogens and antiestrogens in breast cancer cells

artículo científico publicado en 2003

Dopamine is an aryl hydrocarbon receptor agonist

scientific article published on 09 September 2020

Dose-response immunotoxicities of commercial polychlorinated biphenyls (PCBs) and their interaction with 2,3,7,8-tetrachlorodibenzo-p-dioxin

artículo científico publicado en 1989

Drugs that target specificity proteins downregulate epidermal growth factor receptor in bladder cancer cells

artículo científico publicado en 2010

Dual targeting of Nur77 and AMPKα by isoalantolactone inhibits adipogenesis in vitro and decreases body fat mass in vivo

scientific article published on 11 December 2018

Editor's Highlight: Microbial-Derived 1,4-Dihydroxy-2-naphthoic Acid and Related Compounds as Aryl Hydrocarbon Receptor Agonists/Antagonists: Structure-Activity Relationships and Receptor Modeling.

artículo científico publicado en 2016

Effect of diet and intestinal AhR expression on fecal microbiome and metabolomic profiles

scientific article published on 30 November 2020

Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin and related compounds on the occupied nuclear estrogen receptor in MCF-7 human breast cancer cells

artículo científico publicado en 1990

Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on I-compounds in hepatic DNA of Sprague-Dawley rats: sex-specific effects and structure-activity relationships

artículo científico publicado en 1990

Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on hepatic and uterine estrogen receptor levels in rats

artículo científico publicado en 1987

Effects of benzo-a-pyrene on oxytocin-induced Ca2+ oscillations in myometrial cells.

artículo científico publicado en 2006

Effects of cytochrome P-450 monooxygenase inducers on mouse hepatic microsomal metabolism of testosterone and alkoxyresorufins

artículo científico publicado en 1990

Effects of high-fat diet and intestinal aryl hydrocarbon receptor deletion on colon carcinogenesis

scientific article published on 06 January 2020

Effects of ligand structure on the in vitro transformation of the rat cytosolic aryl hydrocarbon receptor

artículo científico publicado el 15 de agosto de 1992

Effects of structure on binding to the 2,3,7,8-TCDD receptor protein and AHH induction--halogenated biphenyls

artículo científico publicado en 1985

Effects of substituents on the cytosolic receptor-binding avidities and aryl hydrocarbon hydroxylase induction potencies of 7-substituted 2,3-dichlorodibenzo-p-dioxins. A quantitative structure-activity relationship analysis

artículo científico publicado en 1985

Electron-donor-acceptor complexing reagents in the analysis of pesticides. V. The analysis of pesticide decomposition products via electron-donor-acceptor complexes; photolysis of methoxychlor

artículo científico publicado el 1 de noviembre de 1972

Enhanced Percutaneous Delivery of 1,1-bis(3'-indolyl)-1-(p-chlorophenyl) Methane for Skin Cancer Chemoprevention

artículo científico publicado en 2015

Enhancement of docetaxel anticancer activity by a novel diindolylmethane compound in human non-small cell lung cancer

artículo científico publicado en 2009

Erratum to: Role of the aryl hydrocarbon receptor in carcinogenesis and potential as an anti-cancer drug target.

artículo científico publicado en 2017

Erratum: 3,3'-Diindolylmethane (DIM) and its ring-substituted halogenated analogs (ring-DIMs) induce differential mechanisms of survival and death in androgen-dependent and-independent prostate cancer cells

artículo científico publicado en 2016

Estrogen receptor-mediated activation of the serum response element in MCF-7 cells through MAPK-dependent phosphorylation of Elk-1.

artículo científico publicado en 2001

Estrogen receptor/Sp1 complexes are required for induction of cad gene expression by 17beta-estradiol in breast cancer cells

artículo científico publicado en 2003

Estrogen regulates transcription of the ovine oxytocin receptor gene through GC-rich SP1 promoter elements.

artículo científico publicado en 2005

Estrogen regulation of c-fos gene expression through phosphatidylinositol-3-kinase-dependent activation of serum response factor in MCF-7 breast cancer cells

artículo científico publicado en 2002

Estrogen regulation of vascular endothelial growth factor gene expression in ZR-75 breast cancer cells through interaction of estrogen receptor alpha and SP proteins

artículo científico publicado en 2004

Estrogen up-regulation of p53 gene expression in MCF-7 breast cancer cells is mediated by calmodulin kinase IV-dependent activation of a nuclear factor kappaB/CCAAT-binding transcription factor-1 complex

artículo científico publicado en 2002

Estrogen-dependent regulation of ornithine decarboxylase in breast cancer cells through activation of nongenomic cAMP-dependent pathways

artículo científico publicado en 2004

Estrogenic activity of a dieldrin/toxaphene mixture in the mouse uterus, MCF-7 human breast cancer cells, and yeast-based estrogen receptor assays: no apparent synergism

artículo científico publicado en 1997

Evaluation of Spray BIO-Max DIM-P in Dogs for Oral Bioavailability and in Nu/nu Mice Bearing Orthotopic/Metastatic Lung Tumor Models for Anticancer Activity

artículo científico publicado en 2015

Evaluation of self-emulsified DIM-14 in dogs for oral bioavailability and in Nu/nu mice bearing stem cell lung tumor models for anticancer activity

artículo científico publicado en 2015

Evidence for the mechanism of action of the 2,3,7,8-tetrachlorodibenzo-p-dioxin-mediated decrease of nuclear estrogen receptor levels in wild-type and mutant mouse Hepa 1c1c7 cells

scientific article published on 01 June 1991

Examination of the estrogenicity of 2,4,6,2',6'-pentachlorobiphenyl (PCB 104), its hydroxylated metabolite 2,4,6,2',6'-pentachloro-4-biphenylol (HO-PCB 104), and a further chlorinated derivative, 2,4,6,2',4',6'-hexachlorobiphenyl (PCB 155) ⬇️

artículo científico publicado el 1 de noviembre de 1997

Failure of chloro-S-triazine-derived compounds to induce estrogen receptor-mediated responses in vivo and in vitro

artículo científico publicado en 1996

Flavonoids as aryl hydrocarbon receptor agonists/antagonists: effects of structure and cell context

artículo científico publicado en 2003

Further characterization and applications of the 4-chlorobiphenyl hydroxylase assay

artículo científico publicado en 1981

GT-094, a NO-NSAID, Inhibits Colon Cancer Cell Growth by Activation of a Reactive Oxygen Species-MicroRNA-27a: ZBTB10-Specificity Protein Pathway ⬇️

artículo científico publicado el 14 de diciembre de 2010

Guggulsterones Induce Apoptosis and Differentiation in AML: Identification of Isomer-Specific Antileukemic Activities of the Pregnanedienedione Structure. ⬇️

artículo científico publicado en 2005

Guggulsterones induce apoptosis and differentiation in acute myeloid leukemia: identification of isomer-specific antileukemic activities of the pregnadienedione structure

artículo científico publicado en 2005

HOTAIR is a negative prognostic factor and exhibits pro-oncogenic activity in pancreatic cancer.

artículo científico publicado en 2012

Halogenated biphenyls as AHH inducers: effects of different halogen substituents

artículo científico publicado en 1982

Halogenated biphenyls: molecular toxicology

artículo científico publicado en 1982

Hepatic microsomal enzyme induction by 2,2', 3,3', 4,4'- and 2,2', 3', 4,4', 5-hexachlorobiphenyl

scientific article published on 01 December 1980

Hepta-, hexa-, tetra- and dichloronaphthalene congeners as inducers of hepatic microsomal drug-metabolizing enzymes

artículo científico publicado en 1983

High passage T47D human breast cancer cells: altered endocrine and 2,3,7,8-tetrachlorodibenzo-p-dioxin responsiveness

artículo científico publicado en 1994

Histone Deacetylase Inhibitors Inhibit Rhabdomyosarcoma by Reactive Oxygen Species-Dependent Targeting of Specificity Protein Transcription Factors

artículo científico publicado en 2015

Hormonal regulation of lactate dehydrogenase-A through activation of protein kinase C pathways in MCF-7 breast cancer cells

artículo científico publicado en 2004

Hydroxylated Chalcones as Aryl Hydrocarbon Receptor Agonists: Structure-Activity Effects

artículo científico publicado en 2020

Hydroxylated Polychlorinated Biphenyls (PCBs) as Estrogens and Antiestrogens: Structure–Activity Relationships ⬇️

artículo científico publicado el 1 de julio de 1997

Hypoxia induces proteasome-dependent degradation of estrogen receptor alpha in ZR-75 breast cancer cells

artículo científico publicado en 2002

Identification of 4-chloro-4'-hydroxybiphenyl and 4,4'-dichloro-3-hydroxybiphenyl as metabolites of 4-chloro- and 4,4'-dichlorobiphenyl fed to rats

artículo científico publicado en 1974

Identification of a motif within the 5' regulatory region of pS2 which is responsible for AP-1 binding and TCDD-mediated suppression

artículo científico publicado en 1997

Identification of metabolic dechlorination of highly chlorinated biphenyl in rabbit

artículo científico publicado en 1974

Identification of toxic impurities in commercial diphenylamine

artículo científico publicado el 1 de febrero de 1977

Immunosuppressive and monooxygenase induction activities of highly chlorinated diphenyl ether congeners in C57BL/6 and DBA/2 mice

artículo científico publicado en 1993

Immunosuppressive and monooxygenase induction activities of polychlorinated diphenyl ether congeners in C57BL/6N mice: quantitative structure-activity relationships

artículo científico publicado en 1990

Immunosuppressive effects of highly chlorinated biphenyls and diphenyl ethers on T-cell dependent and independent antigens in mice

scientific article published on 01 December 1993

Immunotoxic potencies of polychlorinated biphenyl (PCB), dibenzofuran (PCDF) and dibenzo-p-dioxin (PCDD) congeners in C57BL/6 and DBA/2 mice

artículo científico publicado en 1993

In vivo profiling of estrogen receptor/specificity protein-dependent transactivation

artículo científico publicado en 2008

Inactivation of the orphan nuclear receptor NR4A1 contributes to apoptosis induction by fangchinoline in pancreatic cancer cells

artículo científico publicado en 2017

Inactivation of the orphan nuclear receptor TR3/Nur77 inhibits pancreatic cancer cell and tumor growth

artículo científico publicado en 2010

Induction of apoptosis and nonsteroidal anti-inflammatory drug-activated gene 1 in pancreatic cancer cells by a glycyrrhetinic acid derivative

artículo científico publicado en 2009

Induction of apoptosis by cannabinoids in prostate and colon cancer cells is phosphatase dependent.

artículo científico publicado en 2011

Induction of both 3-methylcholanthrene- and phenobarbitone-type microsomal enzyme activity by a single polychlorinated biphenyl isomer

artículo científico publicado en 1980

Induction of cytochrome P450-dependent monooxygenase activities in rat hepatoma H-4-IIE cells in culture by 2,3,7,8-tetrachlorodibenzo-p-dioxin and related compounds: mechanistic studies using radiolabeled congeners

artículo científico publicado en 1989

Induction of endoplasmic reticulum-induced stress genes in Panc-1 pancreatic cancer cells is dependent on Sp proteins

artículo científico publicado en 2005

Induction of rat liver microsomal cytochrome P-450 isozymes and epoxide hydrolase by a series of 4'-substituted-2,3,4,5-tetrachlorobiphenyls

scientific article published on 01 December 1988

Induction of the transcriptional repressor ZBTB4 in prostate cancer cells by drug-induced targeting of microRNA-17-92/106b-25 clusters

artículo científico publicado en 2012

Inhalation Delivery of a Novel Diindolylmethane Derivative for the Treatment of Lung Cancer ⬇️

artículo científico publicado el 26 de octubre de 2010

Inhibition of NFkappaB and pancreatic cancer cell and tumor growth by curcumin is dependent on specificity protein down-regulation

artículo científico publicado en 2010

Inhibition of NR4A1 Promotes ROS Accumulation and IL24-Dependent Growth Arrest in Rhabdomyosarcoma

scientific article published on 28 August 2019

Inhibition of bladder tumor growth by 1,1-bis(3'-indolyl)-1-(p-substitutedphenyl)methanes: a new class of peroxisome proliferator-activated receptor gamma agonists

artículo científico publicado en 2006

Inhibition of breast cancer cell growth and induction of cell death by 1,1-bis(3'-indolyl)methane (DIM) and 5,5'-dibromoDIM.

artículo científico publicado en 2005

Inhibition of pancreatic cancer Panc1 cell migration by omeprazole is dependent on aryl hydrocarbon receptor activation of JNK.

artículo científico publicado en 2018

Inhibition of pituitary tumor‐transforming gene‐1 in thyroid cancer cells by drugs that decrease specificity proteins ⬇️

artículo científico publicado el 25 de enero de 2011

Inhibition of rhabdomyosarcoma cell and tumor growth by targeting specificity protein (Sp) transcription factors

artículo científico publicado en 2012

Interaction of methoxychlor and related compounds with estrogen receptor alpha and beta, and androgen receptor: structure-activity studies.

artículo científico publicado en 2000

Interaction of the aryl hydrocarbon receptor ligand 6-methyl-1,3,8-trichlorodibenzofuran with estrogen receptor alpha

artículo científico publicado en 2004

Interferon tau alleviates obesity-induced adipose tissue inflammation and insulin resistance by regulating macrophage polarization

artículo científico publicado en 2014

Interferon-tau activates multiple signal transducer and activator of transcription proteins and has complex effects on interferon-responsive gene transcription in ovine endometrial epithelial cells

artículo científico publicado en 2001

Interleukin-24 (IL24) Is Suppressed by PAX3-FOXO1 and Is a Novel Therapy for Rhabdomyosarcoma

artículo científico publicado en 2018

Investigation of macrophage polarization using bone marrow derived macrophages

artículo científico publicado en 2013

Isoflavones as Ah Receptor Agonists in Colon-Derived Cell Lines: Structure-Activity Relationships

scientific article published on 29 October 2019

Ligand structure-dependent activation of estrogen receptor alpha/Sp by estrogens and xenoestrogens.

artículo científico publicado en 2008

Ligand structure-dependent differences in activation of estrogen receptor alpha in human HepG2 liver and U2 osteogenic cancer cell lines

artículo científico publicado en 2000

Ligand-dependent interactions of the Ah receptor with coactivators in a mammalian two-hybrid assay

artículo científico publicado en 2007

Lipid-based oral delivery systems for skin deposition of a potential chemopreventive DIM derivative: characterization and evaluation

artículo científico publicado en 2016

Loss of aryl hydrocarbon receptor potentiates FoxM1 signaling to enhance self-renewal of colonic stem and progenitor cells

artículo científico publicado en 2020

MDM2 regulates estrogen receptor α and estrogen responsiveness in breast cancer cells

artículo científico publicado en 2011

Mass spectra of fifteen chlorinated aromatic fungicides

artículo científico publicado el 1 de enero de 1971

Mass spectra of some fungicidal organomercury compounds

scientific article published on 01 November 1971

Mechanism of action of 2,3,7,8-tetrachlorodibenzo-p-dioxin antagonists: Characterization of 6-[125I]methyl-8-iodo-1, 3-dichlorodibenzofuran-Ah receptor complexes ⬇️

artículo científico publicado el 1 de enero de 1991

Mechanism of action of aryl hydrocarbon receptor antagonists: inhibition of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced CYP1A1 gene expression

artículo científico publicado el 1 de noviembre de 1992

Mechanism of action of phenethylisothiocyanate and other reactive oxygen species-inducing anticancer agents

artículo científico publicado en 2014

Mechanism of benzo[a]pyrene-induced Cyp1a-1 gene expression in mouse Hepa 1c1c7 cells: Role of the nuclear 6 s and 4 s proteins ⬇️

artículo científico publicado el 1 de enero de 1992

Mechanism of chlorobiphenyl metabolism ⬇️

artículo científico publicado el 1 de septiembre de 1975

Mechanism of inhibition of MDA-MB-468 breast cancer cell growth by 2,3,7,8-tetrachlorodibenzo-p-dioxin

artículo científico publicado en 1997

Mechanism of metformin-dependent inhibition of mammalian target of rapamycin (mTOR) and Ras activity in pancreatic cancer: role of specificity protein (Sp) transcription factors

artículo científico publicado en 2014

Mechanistic relationships between hepatic genotoxicity and carcinogenicity in male B6C3F1 mice treated with polycyclic aromatic hydrocarbon mixtures

artículo científico publicado en 2014

Metabolism of 4,4'-dihalogenobiphenyls

artículo científico publicado el 1 de enero de 1976

Metabolism of bromobenzenes in the rabbit ⬇️

artículo científico publicado el 1 de marzo de 1976

Metabolism of chlorinated naphthalenes

artículo científico publicado en 1976

Metabolism of chlorobiphenyls in the goat and cow

artículo científico publicado el 1 de marzo de 1975

Metabolism of the systemic fungicide 2,5-dimethyl-3-furancarboxylic acid anilide (BAS 3191) by Rhizopus japonicus and related fungi ⬇️

artículo científico publicado el 1 de enero de 1972

Metformin inhibits pancreatic cancer cell and tumor growth and downregulates Sp transcription factors

scientific article published on 26 June 2013

Metformin-induced anticancer activities: recent insights

artículo científico publicado en 2017

Methods for xenoestrogen testing

scientific article published on 01 December 1998

Methyl 2-cyano-3,11-dioxo-18 beta-olean-1,12-dien-30-oate is a peroxisome proliferator-activated receptor-gamma agonist that induces receptor-independent apoptosis in LNCaP prostate cancer cells

artículo científico publicado en 2007

Methyl 2-cyano-3,12-dioxooleana-1,9-dien-28-oate decreases specificity protein transcription factors and inhibits pancreatic tumor growth: role of microRNA-27a

artículo científico publicado en 2010

MiR-150 Inhibits MLL-AF9 Associated Leukemia By Suppressing Leukemic Stem Cells ⬇️

artículo científico publicado en 2013

MicroRNA-223 is a crucial mediator of PPARγ-regulated alternative macrophage activation

artículo científico publicado en 2015

MicroRNA-26b represses colon cancer cell proliferation by inhibiting lymphoid enhancer factor 1 expression.

artículo científico publicado en 2014

MicroRNA-27a Indirectly Regulates Estrogen Receptor {alpha} Expression and Hormone Responsiveness in MCF-7 Breast Cancer Cells

artículo científico publicado en 2010

Microbial hydroxylation of the herbicide N-(3,4-dichlorophenyl)methacrylamide (dicryl).

artículo científico publicado en 1973

Microbiome-derived tryptophan metabolites and their aryl hydrocarbon receptor-dependent agonist and antagonist activities

artículo científico publicado en 2014

Minireview: role of orphan nuclear receptors in cancer and potential as drug targets

scientific article published on 02 December 2013

Mithramycin A inhibits myeloid cell leukemia-1 to induce apoptosis in oral squamous cell carcinomas and tumor xenograft through activation of Bax and oligomerization

artículo científico publicado en 2012

Modulation of rat hepatic microsomal testosterone hydroxylases by 2,3,7,8-tetrachlorodibenzo-p-dioxin and related toxic isostereomers

artículo científico publicado en 1985

Molecular mechanism of inhibitory aryl hydrocarbon receptor-estrogen receptor/Sp1 cross talk in breast cancer cells.

artículo científico publicado en 2006

Multiphoton spectral analysis of benzo[a]pyrene uptake and metabolism in a rat liver cell line

artículo científico publicado en 2011

Multiphoton spectral analysis of benzo[a]pyrene uptake and metabolism in breast epithelial cell lines

artículo científico publicado en 2009

NR4A1 Antagonists Inhibit β1-Integrin-Dependent Breast Cancer Cell Migration

artículo científico publicado en 2016

Naringenin: a weakly estrogenic bioflavonoid that exhibits antiestrogenic activity

artículo científico publicado en 1995

Neuroprotective efficacy and pharmacokinetic behavior of novel anti-inflammatory para-phenyl substituted diindolylmethanes in a mouse model of Parkinson's disease.

artículo científico publicado en 2013

Non-classical genomic estrogen receptor (ER)/specificity protein and ER/activating protein-1 signaling pathways

artículo científico publicado en 2008

Non-dioxin-like AhR ligands in a mouse peanut allergy model.

artículo científico publicado en 2012

Nonadditive interactive effects of polychlorinated biphenyl congeners in rats: role of the 2,3,7,8-tetrachlorodibenzo-p-dioxin receptor

scientific article published on 01 September 1987

Novel diindolylmethane derivatives based NLC formulations to improve the oral bioavailability and anticancer effects in triple negative breast cancer.

artículo científico publicado en 2016

Novel para-phenyl substituted diindolylmethanes protect against MPTP neurotoxicity and suppress glial activation in a mouse model of Parkinson's disease

artículo científico publicado en 2014

Nuclear Receptor 4A1 (NR4A1) as a Drug Target for Renal Cell Adenocarcinoma

artículo científico publicado en 2015

Nuclear Receptor 4A2 (NR4A2/NURR1) Regulates Autophagy and Chemoresistance in Pancreatic Ductal Adenocarcinoma

artículo científico publicado en 2021

Nuclear receptor 4A (NR4A) family - orphans no more

artículo científico publicado en 2015

Nuclear receptor 4A1 (NR4A1) antagonists induce ROS-dependent inhibition of mTOR signaling in endometrial cancer

scientific article published on 30 April 2019

Nuclear receptor 4A1 (NR4A1) as a drug target for treating rhabdomyosarcoma (RMS).

artículo científico publicado en 2016

Nuclear receptor 4A1 as a drug target for breast cancer chemotherapy

artículo científico publicado en 2015

Nuclear receptor 4A2 (NR4A2) is a druggable target for glioblastomas

scientific article published on 21 November 2019

Nuclear receptor-mediated transactivation through interaction with Sp proteins

artículo científico publicado en 2004

Nur77 agonists induce proapoptotic genes and responses in colon cancer cells through nuclear receptor-dependent and nuclear receptor-independent pathways

artículo científico publicado en 2007

Octachloronaphthalene induction of hepatic microsomal aryl hydrocarbon hydroxylase activity in the immature male rat ⬇️

artículo científico publicado el 1 de enero de 1981

Omeprazole Inhibits Glioblastoma Cell Invasion and Tumor Growth

artículo científico publicado en 2020

Omeprazole Inhibits Pancreatic Cancer Cell Invasion through a Nongenomic Aryl Hydrocarbon Receptor Pathway

scientific article published on 09 April 2015

Oncogenic microRNA-27a is a target for anticancer agent methyl 2-cyano-3,11-dioxo-18beta-olean-1,12-dien-30-oate in colon cancer cells

scientific article published on October 2009

Organochlorine exposure and risk for breast cancer

artículo científico publicado en 1997

PAH Particles Perturb Prenatal Processes and Phenotypes: Protection from Deficits in Object Discrimination Afforded by Dampening of Brain Oxidoreductase Following In Utero Exposure to Inhaled Benzo(a)pyrene ⬇️

artículo científico publicado el 10 de octubre de 2011

PAX3-FOXO1A Expression in Rhabdomyosarcoma Is Driven by the Targetable Nuclear Receptor NR4A1.

artículo científico publicado en 2016

PCB isomers and congeners: induction of aryl hydrocarbon hydroxylase and ethoxyresorufin O-deethylase enzyme activities in rat hepatoma cells

scientific article published on 01 September 1982

PCBs: structure-function relationships and mechanism of action

artículo científico publicado en 1985

Partial antagonism of 2,3,7,8-tetrachlorodibenzo-p-dioxin-mediated induction of aryl hydrocarbon hydroxylase by 6-methyl-1,3,8-trichlorodibenzofuran: mechanistic studies

scientific article published on 01 May 1989

Penfluridol Represses Integrin Expression in Breast Cancer through Induction of Reactive Oxygen Species and Downregulation of Sp Transcription Factors

artículo científico publicado en 2016

Peroxisome proliferator-activated receptor gamma agonists induce proteasome-dependent degradation of cyclin D1 and estrogen receptor alpha in MCF-7 breast cancer cells.

artículo científico publicado en 2003

Peroxisome proliferator-activated receptor gamma-dependent activation of p21 in Panc-28 pancreatic cancer cells involves Sp1 and Sp4 proteins

artículo científico publicado en 2004

Peroxisome proliferator-activated receptor gamma-dependent activity of indole ring-substituted 1,1-bis(3'-indolyl)-1-(p-biphenyl)methanes in cancer cells

artículo científico publicado en 2009

Pharmacokinetic evaluation and In Vitro–In Vivo Correlation (IVIVC) of novel methylene-substituted 3,3′ diindolylmethane (DIM) ⬇️

artículo científico publicado el 8 de febrero de 2012

Pharmacologic doses of ascorbic acid repress specificity protein (Sp) transcription factors and Sp-regulated genes in colon cancer cells

artículo científico publicado en 2011

Photoaffinity labeling of the nuclear Ah receptor from mouse Hepa 1c1c7 cells using 2,3,7,8-[3H]tetrachlorodibenzo-p-dioxin

artículo científico publicado en 1989

Photochemical Degradation of Chloro-biphenyls (PCBs).

artículo científico publicado en 1972

Photochemical degradation of di- and octachlorodibenzofuran

artículo científico publicado en 1973

Photodecomposition of unsymmetrical polychlorobisphenyls

artículo científico publicado el 1 de mayo de 1975

Photodegradation of polybromobiphenyls (PBB)

artículo científico publicado el 1 de septiembre de 1976

Photodegradation of polychloronaphthalenes in methanol solution ⬇️

artículo científico publicado el 1 de septiembre de 1975

Piperlongumine Induces Reactive Oxygen Species (ROS)-Dependent Downregulation of Specificity Protein Transcription Factors.

artículo científico publicado en 2017

Polybrominated dibenzo-p-dioxins and related compounds: quantitative in vivo and in vitro structure-activity relationships

artículo científico publicado en 1987

Polybrominated dibenzo-p-dioxins, dibenzofurans, and biphenyls: inclusion in the toxicity equivalency factor concept for dioxin-like compounds

artículo científico publicado en 2013

Polychlorinated Biphenyls: Metabolic Behavior of Pure Isomers in Pigeons, Rats, and Brook Trout ⬇️

artículo científico publicado el 20 de octubre de 1972

Polychlorinated Biphenyls: Photolysis of 2,4,6,2′,4′,6′-Hexachlorobiphenyl

artículo científico publicado en 1971

Polychlorinated benzene and phenol congeners as inducers of rat hepatic drug-metabolizing enzymes in immature male Wistar rats

artículo científico publicado en 1983

Polychlorinated biphenyls as inducers of hepatic microsomal enzymes: structure-activity rules

scientific article published on 01 June 1980

Polychlorinated biphenyls as phenobarbitone-type inducers of microsomal enzymes. Structure-activity relationships for a series of 2,4-dichloro-substituted congeners

scientific article published on 01 October 1983

Polychlorinated biphenyls: synthesis of some individual chlorobiphenyls

artículo científico publicado en 1971

Polychlorinated dibenzo-p-dioxins and dibenzofurans associated with wood-preserving chemical sites: biomonitoring with pine needles

Polychlorinated dibenzo-p-dioxins: quantitative in vitro and in vivo structure-activity relationships

artículo científico publicado en 1986

Polychlorinated dibenzofurans (PCDFs): correlation between in vivo and in vitro structure-activity relationships

artículo científico publicado en 1985

Polychlorinated dibenzofurans (PCDFs): effects of structure on binding to the 2,3,7,8-TCDD cytosolic receptor protein, AHH induction and toxicity

artículo científico publicado en 1984

Polychlorinated dibenzofurans as 2,3,7,8-TCDD antagonists: in vitro inhibition of monooxygenase enzyme induction

artículo científico publicado en 1986

Polychlorinated naphthalenes as hepatic microsomal enzyme inducers in the immature male rat

artículo científico publicado en 1981

Potency of combined estrogenic pesticides

artículo científico publicado en 1997

Potent inhibition of breast cancer by bis-indole-derived nuclear receptor 4A1 (NR4A1) antagonists

artículo científico publicado en 2019

Preparation, gas chromatographic behavior, and spectroscopic properties of hydroxylated chlorobiphenyls.

artículo científico publicado en 1974

Problems for risk assessment of endocrine-active estrogenic compounds

artículo científico publicado en 2002

Quantitative structure-activity relationships: analysis of interactions of 2,3,7,8-tetrachlorodibenzo-p-dioxin and 2-substituted analogues with rat, mouse, guinea pig, and hamster cytosolic receptor

artículo científico publicado en 1987

REACTIVE OXYGEN SPECIES AND COLORECTAL CANCER.

artículo científico publicado en 2013

RNAi and cancer: Implications and applications.

scientific article published on 28 February 2006

Radioligand-dependent differences in the molecular properties of the mouse and rat hepatic aryl hydrocarbon receptor complexes

artículo científico publicado en 1988

Reactive Oxygen Species (ROS)-Inducing Triterpenoid Inhibits Rhabdomyosarcoma Cell and Tumor Growth through Targeting Sp Transcription Factors

scientific article published on 04 January 2019

Reconstituted halogenated hydrocarbon pesticide and pollutant mixtures found in human tissues: effects on the immature male Wistar rat after short-term exposure

artículo científico publicado en 1985

Reconstituted human breast milk PCBs as potent inducers of aryl hydrocarbon hydroxylase

scientific article published on 01 September 1980

Reconstruction of nuclear receptor network reveals that NR2E3 is a novel upstream regulator of ESR1 in breast cancer

scientific journal article

Regulation of KiSS-1 metastasis suppressor gene expression in breast cancer cells by direct interaction of transcription factors activator protein-2alpha and specificity protein-1.

artículo científico publicado en 2005

Regulation of vascular endothelial growth factor receptor-1 expression by specificity proteins 1, 3, and 4 in pancreatic cancer cells

artículo científico publicado en 2007

Regulation of vascular endothelial growth factor receptor-2 expression in pancreatic cancer cells by Sp proteins

artículo científico publicado en 2006

Resveratrol and quercetin in combination have anticancer activity in colon cancer cells and repress oncogenic microRNA-27a

artículo científico publicado en 2013

Retention times and electron-capture detector responses of some individual chlorobiphenyls ⬇️

artículo científico publicado el 1 de marzo de 1971

Ring-substituted analogs of 3,3'-diindolylmethane (DIM) induce apoptosis and necrosis in androgen-dependent and -independent prostate cancer cells.

artículo científico publicado en 2013

Role of SP transcription factors in hormone-dependent modulation of genes in MCF-7 breast cancer cells: microarray and RNA interference studies

artículo científico publicado en 2008

Role of Sp proteins in regulation of vascular endothelial growth factor expression and proliferation of pancreatic cancer cells

artículo científico publicado en 2004

Role of metastasis-associated lung adenocarcinoma transcript-1 (MALAT-1) in pancreatic cancer.

artículo científico publicado en 2018

Role of peroxisome proliferator-activated receptor-gamma and its coactivator DRIP205 in cellular responses to CDDO (RTA-401) in acute myelogenous leukemia

artículo científico publicado en 2010

Role of specificity protein transcription factors in estrogen-induced gene expression in MCF-7 breast cancer cells.

artículo científico publicado en 2007

Role of the aryl hydrocarbon receptor in carcinogenesis and potential as a drug target

artículo científico publicado en 2013

Role of the aryl hydrocarbon receptor in carcinogenesis and potential as an anti-cancer drug target.

artículo científico publicado en 2017

Short Chain Fatty Acids Enhance Aryl Hydrocarbon (Ah) Responsiveness in Mouse Colonocytes and Caco-2 Human Colon Cancer Cells

artículo científico publicado en 2017

Small inhibitory RNA duplexes for Sp1 mRNA block basal and estrogen-induced gene expression and cell cycle progression in MCF-7 breast cancer cells

artículo científico publicado en 2002

Small molecule tolfenamic acid inhibits PC-3 cell proliferation and invasion in vitro, and tumor growth in orthotopic mouse model for prostate cancer.

artículo científico publicado en 2012

Specificity Protein Transcription Factors and Cancer: Opportunities for Drug Development

artículo científico publicado en 2018

Specificity protein (Sp) transcription factors Sp1, Sp3 and Sp4 are non-oncogene addiction genes in cancer cells

artículo científico publicado en 2016

Specificity protein (Sp) transcription factors and metformin regulate expression of the long non-coding RNA HULC.

artículo científico publicado en 2015

Structure-Dependent Modulation of Aryl Hydrocarbon Receptor-Mediated Activities by Flavones.

artículo científico publicado en 2018

Structure-dependent Ah receptor agonist activities of chlorinated biphenylenes

artículo científico publicado en 2006

Structure-dependent activation of NR4A2 (Nurr1) by 1,1-bis(3′-indolyl)-1-(aromatic)methane analogs in pancreatic cancer cells ⬇️

artículo científico publicado el 3 de marzo de 2012

Structure-dependent activation of endoplasmic reticulum stress-mediated apoptosis in pancreatic cancer by 1,1-bis(3'-indoly)-1-(p-substituted phenyl)methanes

artículo científico publicado en 2008

Structure-dependent activation of gene expression by bis-indole and quinoline-derived activators of nuclear receptor 4A2

artículo científico publicado en 2019

Structure-dependent activity of glycyrrhetinic acid derivatives as peroxisome proliferator-activated receptor {gamma} agonists in colon cancer cells

artículo científico publicado en 2007

Structure-dependent induction of aryl hydrocarbon hydroxylase activity in C57BL/6 mice by 2,3,7,8-tetrachlorodibenzo-p-dioxin and related congeners: mechanistic studies

artículo científico publicado en 1990

Structure-dependent induction of aryl hydrocarbon hydroxylase in human breast cancer cell lines and characterization of the Ah receptor

artículo científico publicado en 1989

Structure-dependent inhibition of bladder and pancreatic cancer cell growth by 2-substituted glycyrrhetinic and ursolic acid derivatives

artículo científico publicado en 2008

Studies on the relationship between estrogen receptor content, glutathione S-transferase pi expression, and induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin and drug resistance in human breast cancer cells

scientific article published on 01 December 1997

Substituted polychlorinated dibenzofuran receptor binding affinities and aryl hydrocarbon hydroxylase induction potencies--a QSAR analysis

artículo científico publicado en 1986

Sulindac sulfide inhibits colon cancer cell growth and downregulates specificity protein transcription factors

artículo científico publicado en 2015

Suppression of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced nitric-oxide synthase 2 expression in astrocytes by a novel diindolylmethane analog protects striatal neurons against apoptosis

scientific article published on 07 October 2008

Synergistic interactions of 2,3,7,8-TCDD and 2,2',4,4',5,5'-hexachlorobiphenyl in C57BL/6J and DBA/2J mice: role of the Ah receptor

artículo científico publicado en 1987

Synthesis and characterization of hydroxylated polychlorinated biphenyls (PCBs) identified in human serum.

artículo científico publicado en 1995

Synthesis and spectroscopic and gas chromatographic behavior of isomeric chlorinated terphenyls

artículo científico publicado el 1 de marzo de 1977

Synthesis of the Octa- and nonachlorobiphenyl isomers and congeners and their quantitation in commercial polychlorinated biphenyls and identification in human breast milk

scientific article published on 01 May 1981

Synthesis, biologic and toxic effects of the major 2,3,7,8-tetrachlorodibenzo-p-dioxin metabolites in the rat.

artículo científico publicado en 1986

Synthetic triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid induces growth arrest in HER2-overexpressing breast cancer cells

artículo científico publicado en 2006

TGFβ-Induced Lung Cancer Cell Migration Is NR4A1-Dependent

artículo científico publicado en 2018

THE HISTONE METHYLTRANSFERASE GENE G9A IS REGULATED BY NUCLEAR RECEPTOR 4A1 (NR4A1) IN ALVEOLAR RHABDOMYOSARCOMA CELLS

scientific article published on 04 December 2020

Targeting NR4A1 (TR3) in cancer cells and tumors ⬇️

artículo científico publicado el 5 de enero de 2011

Teratogenicity and immunotoxicity of 3,3',4,4',5-pentachlorobiphenyl in C57BL/6 mice

artículo científico publicado en 1993

The 2005 World Health Organization reevaluation of human and Mammalian toxic equivalency factors for dioxins and dioxin-like compounds

artículo científico publicado en 2006

The Aryl Hydrocarbon Receptor (AhR) as a Drug Target for Cancer Chemotherapy

artículo científico publicado en 2017

The Metabolism of 4-Chlorobiphenyl in the Pig ⬇️

artículo científico publicado el 1 de junio de 1975

The Metabolism of 4′-Chloro-4-biphenylol in the Rat ⬇️

artículo científico publicado el 1 de abril de 1975

The Nurr1 Activator 1,1-Bis(3'-Indolyl)-1-(p-Chlorophenyl)Methane Blocks Inflammatory Gene Expression in BV-2 Microglial Cells by Inhibiting Nuclear Factor κB

artículo científico publicado en 2015

The Nurr1 Ligand,1,1-bis(3'-Indolyl)-1-(p-Chlorophenyl)Methane, Modulates Glial Reactivity and Is Neuroprotective in MPTP-Induced Parkinsonism.

artículo científico publicado en 2018

The Paradoxical Roles of Orphan Nuclear Receptor 4A (NR4A) in Cancer

scientific article published on 26 October 2020

The Role of Self-Nanoemulsifying Drug Delivery Systems of CDODA-Me in Sensitizing Erlotinib-Resistant Non-Small Cell Lung Cancer

scientific article published on 15 January 2020

The aryl hydrocarbon receptor as a target for estrogen receptor-negative breast cancer chemotherapy

artículo científico publicado en 2009

The aryl hydrocarbon receptor is a tumor suppressor-like gene in glioblastoma

scientific article published on 06 June 2019

The aryl hydrocarbon receptor ligand omeprazole inhibits breast cancer cell invasion and metastasis

artículo científico publicado en 2014

The aryl hydrocarbon receptor mediates degradation of estrogen receptor alpha through activation of proteasomes

artículo científico publicado en 2003

The bioactive compounds alpha-chaconine and gallic acid in potato extracts decrease survival and induce apoptosis in LNCaP and PC3 prostate cancer cells.

artículo científico publicado en 2010

The biologic and toxic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin in chickens

artículo científico publicado en 1986

The cannabinoid WIN 55,212-2 decreases specificity protein transcription factors and the oncogenic cap protein eIF4E in colon cancer cells

artículo científico publicado en 2013

The comparative biologic and toxic potencies of polychlorinated biphenyls and polybrominated biphenyls ⬇️

artículo científico publicado el 15 de septiembre de 1983

The cytochrome P-450-mediated metabolism of biphenyl and the 4-halobiphenyls

artículo científico publicado en 1981

The cytosolic receptor binding affinities and AHH induction potencies of 29 polynuclear aromatic hydrocarbons

artículo científico publicado en 1986

The drug resistance suppression induced by curcuminoids in colon cancer SW-480 cells is mediated by reactive oxygen species-induced disruption of the microRNA-27a-ZBTB10-Sp axis.

artículo científico publicado en 2013

The effects of organochlorine pesticides as inducers of testosterone and benzo[a]pyrene hydroxylases

artículo científico publicado en 1987

The effects of ortho chloro substituents on the retention of PCB isomers in rat, rabbit, Japanese quail, guinea pig and trout

artículo científico publicado en 1980

The effects of twenty-two organochlorine pesticides as inducers of the hepatic drug-metabolizing enzymes

artículo científico publicado en 1983

The in vitro hydroxylation of 4'-chloro-4-biphenylol by a mushroom tyrosinase preparation

artículo científico publicado el 1 de enero de 1976

The long non-coding RNA HOTTIP enhances pancreatic cancer cell proliferation, survival and migration.

artículo científico publicado en 2015

The mass spectra of polychlorinated biphenyls

artículo científico publicado en 1972

The metabolism of chlorinated aromatic pollutants by the frog

artículo científico publicado el 1 de noviembre de 1976

The nonsteroidal anti-inflammatory drug tolfenamic acid inhibits BT474 and SKBR3 breast cancer cell and tumor growth by repressing erbB2 expression

artículo científico publicado en 2009

The nuclear orphan receptor NR4A1 regulates β1-integrin expression in pancreatic and colon cancer cells and can be targeted by NR4A1 antagonists

artículo científico publicado en 2017

The nuclear receptor TR3 regulates mTORC1 signaling in lung cancer cells expressing wild-type p53.

artículo científico publicado en 2011

The oncogenic microRNA-27a targets genes that regulate specificity protein transcription factors and the G2-M checkpoint in MDA-MB-231 breast cancer cells.

artículo científico publicado en 2007

The origin, fate, and health effects of combustion by-products: a research framework

artículo científico publicado en 2002

The orphan nuclear receptor NR4A1 (Nur77) regulates oxidative and endoplasmic reticulum stress in pancreatic cancer cells.

artículo científico publicado en 2014

The p38 MAPK pathway is critical for 5,5'-dibromodiindolylmethane-induced apoptosis to prevent oral squamous carcinoma cells

artículo científico publicado en 2010

The peroxisome proliferator-activated receptor-gamma agonist 1,1-bis(3'-indolyl)-1-(p-trifluoromethylphenyl)methane suppresses manganese-induced production of nitric oxide in astrocytes and inhibits apoptosis in cocultured PC12 cells

artículo científico publicado en 2008

The structure-dependent effects of heptachlorodibenzofuran isomers in male C57BL/6 mice: immunotoxicity and monooxygenase enzyme induction

artículo científico publicado en 1990

The transcriptional repressor ZBTB4 regulates EZH2 through a MicroRNA-ZBTB4-specificity protein signaling axis

artículo científico publicado en 2014

The ultraviolet absorption spectra of some chlorinated biphenyls

artículo científico publicado en 1976

Theranostic tumor homing nanocarriers for the treatment of lung cancer

artículo científico publicado en 2013

Therapeutic applications of NSAIDS in cancer special emphasis on tolfenamic acid ⬇️

artículo científico publicado el 1 de enero de 2011

Tolfenamic acid and pancreatic cancer growth, angiogenesis, and Sp protein degradation

artículo científico publicado en 2006

Tolfenamic acid decreases c-Met expression through Sp proteins degradation and inhibits lung cancer cells growth and tumor formation in orthotopic mice

artículo científico publicado en 2009

Tolfenamic acid enhances pancreatic cancer cell and tumor response to radiation therapy by inhibiting survivin protein expression

artículo científico publicado en 2009

Tolfenamic acid inhibits colon cancer cell and tumor growth and induces degradation of specificity protein (Sp) transcription factors

artículo científico publicado en 2013

Tolfenamic acid inhibits esophageal cancer through repression of specificity proteins and c-Met.

artículo científico publicado en 2009

Toxic equivalency factors (TEFs) for PCBs, PCDDs, PCDFs for humans and wildlife

artículo científico publicado en 1998

Toxicology of environmental estrogens

artículo científico publicado en 2001

Transcription factor Sp1, also known as specificity protein 1 as a therapeutic target

artículo científico

Transcriptional activation of heat shock protein 27 gene expression by 17beta-estradiol and modulation by antiestrogens and aryl hydrocarbon receptor agonists

artículo científico publicado en 2001

Transforming Growth Factor β/NR4A1-Inducible Breast Cancer Cell Migration and Epithelial-to-Mesenchymal Transition Is p38α (Mitogen-Activated Protein Kinase 14) Dependent

artículo científico publicado en 2017

Ultra-flexible nanocarriers for enhanced topical delivery of a highly lipophilic antioxidative molecule for skin cancer chemoprevention

artículo científico publicado en 2016

Unifying mechanisms of action of the anticancer activities of triterpenoids and synthetic analogs

artículo científico publicado en 2012

Vascular endothelial growth factor receptor-2 expression is down-regulated by 17beta-estradiol in MCF-7 breast cancer cells by estrogen receptor alpha/Sp proteins

artículo científico publicado en 2007

Vascular endothelial growth factor receptor-2 expression is induced by 17beta-estradiol in ZR-75 breast cancer cells by estrogen receptor alpha/Sp proteins.

artículo científico publicado en 2006

Vitamin D-interacting protein 205 (DRIP205) coactivation of estrogen receptor alpha (ERalpha) involves multiple domains of both proteins

artículo científico publicado en 2004

miR-150 blocks MLL-AF9-associated leukemia through oncogene repression.

artículo científico publicado en 2013

miR-150 regulates obesity-associated insulin resistance by controlling B cell functions

artículo científico publicado en 2016

p21 expression is induced by activation of nuclear nerve growth factor-induced Balpha (Nur77) in pancreatic cancer cells

artículo científico publicado en 2009

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