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A Cell-Free Approach Based on Phospholipid Characterization for Determination of the Cell Specific Unbound Drug Fraction (fu,cell)

scientific article published on 07 November 2019

A Comparative Analysis of Cytochrome P450 Activities in Paired Liver and Small Intestinal Samples from Patients with Obesity

artículo científico publicado en 2019

A human intestinal M-cell-like model for investigating particle, antigen and microorganism translocation.

artículo científico publicado en 2017

A new opening for orally taken peptide drugs

scientific article published on 01 January 2020

Anti-Rift Valley fever virus activity in vitro, pre-clinical pharmacokinetics and oral bioavailability of benzavir-2, a broad-acting antiviral compound.

artículo científico publicado en 2018

Cell-type-resolved proteomic analysis of the human liver

scientific article published on 03 April 2020

Correction to Piperazin-1-ylpyridazine Derivatives Are a Novel Class of Human dCTP Pyrophosphatase 1 Inhibitors

artículo científico publicado en 2017

Corrigendum: MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool

artículo científico publicado en 2017

Discovery of the First Potent and Selective Inhibitors of Human dCTP Pyrophosphatase 1

artículo científico publicado en 2016

Exploiting loss of heterozygosity for allele-selective colorectal cancer chemotherapy

scientific article published on 11 March 2020

Global variability analysis of mRNA and protein concentrations across and within human tissues

artículo científico publicado en 2019

Identification of Triazolothiadiazoles as Potent Inhibitors of the dCTP Pyrophosphatase 1.

artículo científico publicado en 2017

Illuminating the function of the orphan transporter, SLC22A10, in humans and other primates

artículo científico publicado en 2024

Improved predictions of time-dependent drug-drug interactions by determination of cytosolic drug concentrations

scientific article published on 10 April 2019

Influence of Proteome Profiles and Intracellular Drug Exposure on Differences in CYP Activity in Donor-Matched Human Liver Microsomes and Hepatocytes

artículo científico publicado en 2021

MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool

artículo científico publicado en 2014

Piperazin-1-ylpyridazine Derivatives Are a Novel Class of Human dCTP Pyrophosphatase 1 Inhibitors

artículo científico publicado en 2017

Small-molecule inhibitor of OGG1 suppresses proinflammatory gene expression and inflammation

artículo científico publicado en 2018