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14th European Meeting on Complement in Human Disease, Jena, Germany, August 17–21, 2013 ⬇️

artículo científico publicado el 6 de julio de 2013

A genome-wide association study identifies key modulators of complement factor H binding to malondialdehyde-epitopes

artículo científico publicado en 2020

A novel antibody against human properdin inhibits the alternative complement system and specifically detects properdin from blood samples.

artículo científico publicado en 2014

Acquisition of human plasminogen facilitates complement evasion by the malaria parasite Plasmodium falciparum

scientific article published on 06 October 2020

Activation of endogenously expressed ion channels by active complement in the retinal pigment epithelium

artículo científico publicado en 2014

Age-related macular degeneration associated polymorphism rs10490924 in ARMS2 results in deficiency of a complement activator

artículo científico publicado en 2017

An imbalance of human complement regulatory proteins CFHR1, CFHR3 and factor H influences risk for age-related macular degeneration (AMD)

artículo científico publicado en 2010

Anaphylatoxins Activate Ca2+, Akt/PI3-Kinase, and FOXO1/FoxP3 in the Retinal Pigment Epithelium

artículo científico publicado en 2017

Anti factor H autoantibodies block C-terminal recognition function of factor H in hemolytic uremic syndrome

artículo científico publicado en 2007

ApoE attenuates unresolvable inflammation by complex formation with activated C1q

artículo científico publicado en 2019

Aspf2 From Recruits Human Immune Regulators for Immune Evasion and Cell Damage

Atypical aHUS: State of the art.

artículo científico publicado en 2015

Autoantibodies in haemolytic uraemic syndrome (HUS).

artículo científico publicado en 2009

Autoimmune forms of thrombotic microangiopathy and membranoproliferative glomerulonephritis: Indications for a disease spectrum and common pathogenic principles

artículo científico publicado en 2009

BBA70 of Borrelia burgdorferi Is a Novel Plasminogen-binding Protein ⬇️

artículo científico publicado el 16 de julio de 2013

BGA66 and BGA71 facilitate complement resistance of Borrelia bavariensis by inhibiting assembly of the membrane attack complex.

artículo científico publicado en 2015

Binding of human complement regulators FHL-1 and factor H to CRASP-1 orthologs of Borrelia burgdorferi

artículo científico publicado en 2006

Binding of human factor H-related protein 1 to serum-resistant Borrelia burgdorferi is mediated by borrelial complement regulator-acquiring surface proteins

artículo científico publicado en 2007

Borrelia valaisiana Resist Complement-Mediated Killing Independently of the Recruitment of Immune Regulators and Inactivation of Complement Components ⬇️

artículo científico publicado el 8 de enero de 2013

C3 deposition glomerulopathy due to a functional factor H defect

artículo científico publicado en 2008

C3-Glomerulopathy Autoantibodies Mediate Distinct Effects on Complement C3- and C5-Convertases.

artículo científico publicado en 2019

CFHR Gene Variations Provide Insights in the Pathogenesis of the Kidney Diseases Atypical Hemolytic Uremic Syndrome and C3 Glomerulopathy

artículo científico publicado en 2020

Candida albicans uses the surface protein Gpm1 to attach to human endothelial cells and to keratinocytes via the adhesive protein vitronectin

artículo científico publicado en 2014

Chronic course of a hemolytic uremic syndrome caused by a deficiency of factor H-related proteins (CFHR1 and CFHR3).

artículo científico publicado en 2008

Combined C3b and Factor B Autoantibodies and MPGN Type II ⬇️

artículo científico publicado el 15 de diciembre de 2011

Complement Factor H-Related 5-Hybrid Proteins Anchor Properdin and Activate Complement at Self-Surfaces

artículo científico publicado en 2015

Complement Inhibitors in Clinical Trials for Glomerular Diseases

artículo científico publicado en 2019

Complement Regulator FHR-3 Is Elevated either Locally or Systemically in a Selection of Autoimmune Diseases

artículo científico publicado en 2016

Complement Resistance of Borrelia burgdorferi Correlates with the Expression of BbCRASP-1, a Novel Linear Plasmid-encoded Surface Protein That Interacts with Human Factor H and FHL-1 and Is Unrelated to Erp Proteins ⬇️

artículo científico publicado el 7 de noviembre de 2003

Complement and diseases: defective alternative pathway control results in kidney and eye diseases

artículo científico publicado en 2006

Complement and innate immune evasion strategies of the human pathogenic fungus Candida albicans

artículo científico

Complement evasion of pathogens: common strategies are shared by diverse organisms

artículo científico publicado en 2007

Complement factor H binds malondialdehyde epitopes and protects from oxidative stress

artículo científico publicado en 2011

Complement factor H related proteins (CFHRs) ⬇️

artículo científico publicado el 3 de julio de 2013

Complement factor H related proteins in immune diseases

artículo científico publicado en 2008

Complement factor H-related hybrid protein deregulates complement in dense deposit disease

artículo científico publicado en 2013

Complement factor H-related proteins CFHR2 and CFHR5 represent novel ligands for the infection-associated CRASP proteins of Borrelia burgdorferi

artículo científico publicado en 2010

Complement regulation at necrotic cell lesions is impaired by the age-related macular degeneration-associated factor-H His402 risk variant

scientific article published on 19 September 2011

Complement regulator-acquiring surface protein 1 of Borrelia burgdorferi binds to human bone morphogenic protein 2, several extracellular matrix proteins, and plasminogen.

artículo científico publicado en 2010

Complement regulator-acquiring surface proteins of Borrelia burgdorferi: a new protein family involved in complement resistance

artículo científico publicado en 2002

Complement regulators and inhibitory proteins

artículo científico publicado en 2009

Complement, Candida, and cytokines: The role of C5a in host response to fungi ⬇️

artículo científico publicado el 1 de abril de 2012

Conserved Patterns of Microbial Immune Escape: Pathogenic Microbes of Diverse Origin Target the Human Terminal Complement Inhibitor Vitronectin via a Single Common Motif

artículo científico publicado en 2016

Contribution of the Infection-Associated Complement Regulator-Acquiring Surface Protein 4 (ErpC) to Complement Resistance ofBorrelia burgdorferi ⬇️

artículo científico publicado el 30 de enero de 2012

CspA from Borrelia burgdorferi Inhibits the Terminal Complement Pathway ⬇️

artículo científico publicado el 13 de agosto de 2013

Cutting Edge: FHR-1 Binding Impairs Factor H-Mediated Complement Evasion by the Malaria Parasite Plasmodium falciparum

scientific article published on 19 November 2018

DEAP-HUS: deficiency of CFHR plasma proteins and autoantibody-positive form of hemolytic uremic syndrome

artículo científico publicado en 2010

De novo gene conversion in the RCA gene cluster (1q32) causes mutations in complement factor H associated with atypical hemolytic uremic syndrome

artículo científico publicado en 2006

Deciphering the ligand-binding sites in the Borrelia burgdorferi complement regulator-acquiring surface protein 2 required for interactions with the human immune regulators factor H and factor H-like protein 1.

artículo científico publicado en 2008

Defective complement control of factor H (Y402H) and FHL-1 in age-related macular degeneration

artículo científico publicado en 2007

Deletion of complement factor H-related genes CFHR1 and CFHR3 is associated with atypical hemolytic uremic syndrome

artículo científico publicado en 2007

Dihydrolipoamide Dehydrogenase of Pseudomonas aeruginosa Is a Surface-Exposed Immune Evasion Protein That Binds Three Members of the Factor H Family and Plasminogen ⬇️

artículo científico publicado el 15 de octubre de 2012

Dual binding specificity of a Borrelia hermsii-associated complement regulator-acquiring surface protein for factor H and plasminogen discloses a putative virulence factor of relapsing fever spirochetes.

artículo científico publicado en 2007

Early growth response proteins (EGR) and nuclear factors of activated T cells (NFAT) form heterodimers and regulate proinflammatory cytokine gene expression

artículo científico publicado en 2003

Early growth response proteins EGR-4 and EGR-3 interact with immune inflammatory mediators NF-kappaB p50 and p65.

artículo científico publicado en 2005

Enolase From Aspergillus fumigatus Is a Moonlighting Protein That Binds the Human Plasma Complement Proteins Factor H, FHL-1, C4BP, and Plasminogen

scientific article published on 22 November 2019

Evaluation of serum sphingolipids and the influence of genetic risk factors in age-related macular degeneration

artículo científico publicado en 2018

FHR-4A: a new factor H-related protein is encoded by the human FHR-4 gene.

artículo científico publicado en 2005

FHR3 Blocks C3d-Mediated Coactivation of Human B Cells.

artículo científico publicado en 2016

Factor H Binds to Extracellular DNA Traps Released from Human Blood Monocytes in Response to Candida albicans

artículo científico publicado en 2016

Factor H and atypical hemolytic uremic syndrome: mutations in the C-terminus cause structural changes and defective recognition functions

artículo científico publicado en 2005

Factor H autoantibodies in atypical hemolytic uremic syndrome correlate with CFHR1/CFHR3 deficiency

artículo científico publicado en 2007

Factor H-related protein 1 (CFHR-1) inhibits complement C5 convertase activity and terminal complex formation

artículo científico publicado en 2009

Factor H-related protein 1 (FHR-1): A complement regulatory protein and guardian of necrotic type surfaces

artículo científico publicado en 2020

Factor I and factor H deficiency in renal diseases: similar defects in the fluid phase have a different outcome at the surface of the glomerular basement membrane.

artículo científico publicado en 2008

Functional characterization of BbCRASP-2, a distinct outer membrane protein of Borrelia burgdorferi that binds host complement regulators factor H and FHL-1

artículo científico publicado en 2006

Functional characterization of Borrelia spielmanii outer surface proteins that interact with distinct members of the human factor H protein family and with plasminogen

artículo científico publicado en 2009

Genetic influences on plasma CFH and CFHR1 concentrations and their role in susceptibility to age-related macular degeneration

artículo científico publicado en 2013

Glycerol-3-Phosphate Dehydrogenase 2 Is a Novel Factor H–, Factor H–like Protein 1–, and Plasminogen-Binding Surface Protein of Candida albicans ⬇️

artículo científico publicado el 29 de noviembre de 2012

HED

scholarly article

Hemolytic uremic syndrome: a factor H mutation (E1172Stop) causes defective complement control at the surface of endothelial cells

artículo científico publicado en 2007

Host-pathogen interactions between the human innate immune system and Candida albicans-understanding and modeling defense and evasion strategies

artículo científico publicado en 2015

Human factor H-related protein 2 (CFHR2) regulates complement activation

artículo científico publicado en 2013

Human pathogenic Borrelia spielmanii sp. nov. resists complement-mediated killing by direct binding of immune regulators factor H and factor H-like protein 1

artículo científico publicado en 2007

Identification and characterization of the factor H and FHL-1 binding complement regulator-acquiring surface protein 1 of the Lyme disease spirochete Borrelia spielmanii sp. nov.

artículo científico publicado en 2008

Immune escape of the human facultative pathogenic yeast Candida albicans: The many faces of the Candida Pra1 protein ⬇️

artículo científico publicado el 11 de mayo de 2011

Immune evasion of Borrelia burgdorferi: insufficient killing of the pathogens by complement and antibody

artículo científico publicado en 2002

Immune evasion of Borrelia burgdorferi: mapping of a complement-inhibitor factor H-binding site of BbCRASP-3, a novel member of the Erp protein family

artículo científico publicado en 2003

Immune modulation by complement receptor 3-dependent human monocyte TGF-β1-transporting vesicles

artículo científico publicado en 2020

Immunological characterization of the complement regulator factor H-binding CRASP and Erp proteins of Borrelia burgdorferi.

artículo científico publicado en 2004

In situ Visualization of C3/C5 Convertases to Differentiate Complement Activation

artículo científico publicado en 2020

Inadequate binding of immune regulator factor H is associated with sensitivity of Borrelia lusitaniae to human complement

artículo científico publicado en 2010

Interaction of Shiga toxin 2 with complement regulators of the factor H protein family

artículo científico publicado en 2013

Kallikrein Cleaves C3 and Activates Complement.

artículo científico publicado en 2017

Long-term data on two sisters with C3GN due to an identical, homozygous CFH mutation and autoantibodies

artículo científico publicado en 2020

Monitoring Surface Reactions by Combined Western Blot-ELISA Analysis

artículo científico publicado en 2019

Mutations in FN1 cause glomerulopathy with fibronectin deposits.

artículo científico publicado en 2008

New insights into disease-specific absence of complement factor H related protein C in mouse models of spontaneous autoimmune diseases

artículo científico publicado en 2014

Novel developments in thrombotic microangiopathies: is there a common link between hemolytic uremic syndrome and thrombotic thrombocytic purpura?

artículo científico publicado en 2011

Pseudomonas aeruginosa Uses Dihydrolipoamide Dehydrogenase (Lpd) to Bind to the Human Terminal Pathway Regulators Vitronectin and Clusterin to Inhibit Terminal Pathway Complement Attack

artículo científico publicado en 2015

Publisher Correction: ApoE attenuates unresolvable inflammation by complex formation with activated C1q

scientific article published on 01 March 2019

Recruitment of complement factor H-like protein 1 promotes intracellular invasion by group A streptococci

artículo científico publicado en 2003

Secreted pH-regulated antigen 1 of Candida albicans blocks activation and conversion of complement C3.

artículo científico publicado en 2010

Sequence variations and protein expression levels of the two immune evasion proteins Gpm1 and Pra1 influence virulence of clinical Candida albicans isolates

artículo científico publicado en 2015

Serum FHR1 binding to necrotic-type cells activates monocytic inflammasome and marks necrotic sites in vasculopathies

scientific article published on 04 July 2019

Standardisation of the factor H autoantibody assay

artículo científico publicado en 2013

Staphylococcus aureus proteins Sbi and Efb recruit human plasmin to degrade complement C3 and C3b.

artículo científico publicado en 2012

Staphylococcus aureus: the multi headed hydra resists and controls human complement response in multiple ways

artículo científico

Streptococcus pneumoniae From Patients With Hemolytic Uremic Syndrome Binds Human Plasminogen via the Surface Protein PspC and Uses Plasmin to Damage Human Endothelial Cells

artículo científico publicado en 2017

The MFHR1 Fusion Protein Is a Novel Synthetic Multitarget Complement Inhibitor with Therapeutic Potential

artículo científico publicado en 2018

The Staphylococcus aureus protein Sbi acts as a complement inhibitor and forms a tripartite complex with host complement Factor H and C3b

artículo científico publicado en 2008

The alternative pathway of complement: a pattern recognition system

artículo científico publicado en 2007

The autoimmune disease DEAP-hemolytic uremic syndrome

artículo científico publicado en 2010

The complement factor H R1210C mutation is associated with atypical hemolytic uremic syndrome

artículo científico publicado en 2008

The complement fitness factor H: role in human diseases and for immune escape of pathogens, like pneumococci

artículo científico publicado en 2008

The host immune regulator factor H interacts via two contact sites with the PspC protein of Streptococcus pneumoniae and mediates adhesion to host epithelial cells

artículo científico publicado en 2007

The interactive Factor H-atypical hemolytic uremic syndrome mutation database and website: update and integration of membrane cofactor protein and Factor I mutations with structural models

artículo científico publicado en 2007

The pH-regulated antigen 1 of Candida albicans binds the human complement inhibitor C4b-binding protein and mediates fungal complement evasion

artículo científico publicado en 2011

The role of complement in AMD.

artículo científico publicado en 2010

The role of complement in C3 glomerulopathy

artículo científico publicado en 2015

The role of defective complement control in hemolytic uremic syndrome

artículo científico publicado en 2006

The secreted Candida albicans protein Pra1 disrupts host defense by broadly targeting and blocking complement C3 and C3 activation fragments

artículo científico publicado en 2017

The yeast Candida albicans evades human complement attack by secretion of aspartic proteases

artículo científico publicado en 2009

Thrombotic microangiopathies: new insights and new challenges

artículo científico publicado en 2010

Tuf of Streptococcus pneumoniae is a surface displayed human complement regulator binding protein

artículo científico publicado en 2014

Versatile roles of CspA orthologs in complement inactivation of serum-resistant Lyme disease spirochetes

artículo científico publicado en 2013

β₂-glycoprotein I, the major target in antiphospholipid syndrome, is a special human complement regulator

artículo científico publicado en 2011

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