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5-Formylcytosine Yields DNA-Protein Cross-Links in Nucleosome Core Particles.

artículo científico publicado en 2017

Aminyl Radical Generation via Tandem Norrish Type I Photocleavage, β-Fragmentation: Independent Generation and Reactivity of the 2'-Deoxyadenosin- N6-yl Radical.

artículo científico publicado en 2017

Biologically relevant oxidants and terminology, classification and nomenclature of oxidatively generated damage to nucleobases and 2-deoxyribose in nucleic acids.

artículo científico publicado en 2012

DNA Damage Emanating From a Neutral Purine Radical Reveals the Sequence Dependent Convergence of the Direct and Indirect Effects of γ-Radiolysis

artículo científico publicado en 2017

DNA-Protein Cross-Link Formation in Nucleosome Core Particles Treated with Methyl Methanesulfonate

artículo científico publicado en 2019

Effect of Histone Lysine Methylation on DNA Lesion Reactivity in Nucleosome Core Particles

scientific article published on 27 March 2019

Enhanced Cleavage at Abasic Sites within Clustered Lesions in Nucleosome Core Particles

artículo científico publicado en 2018

Expanded Substrate Scope of DNA Polymerase θ and DNA Polymerase β: Lyase Activity on 5'-Overhangs and Clustered Lesions

article

Histone Tail Sequences Balance Their Role in Genetic Regulation and the Need to Protect DNA Against Destruction in Nucleosome Core Particles Containing Abasic Sites

artículo científico publicado en 2018

Histone tails decrease N7-methyl-2'-deoxyguanosine depurination and yield DNA-protein cross-links in nucleosome core particles and cells

artículo científico publicado en 2018

In Vitro Bypass of Thymidine Glycol by DNA Polymerase θ Forms Sequence-Dependent Frameshift Mutations.

artículo científico publicado en 2017

Independent Generation and Reactivity of 2'-Deoxyguanosin-N1-yl Radical

artículo científico publicado en 2020

Independent Generation and Reactivity of Thymidine Radical Cations.

artículo científico publicado en 2017

Independent Generation of Reactive Intermediates Leads to an Alternative Mechanism for Strand Damage Induced by Hole Transfer in Poly(dA-T) Sequences

scientific article published on 31 August 2018

Independent Photochemical Generation and Reactivity of Nitrogen-Centered Purine Nucleoside Radicals from Hydrazines

artículo científico publicado en 2017

Light-controlled twister ribozyme with single-molecule detection resolves RNA function in time and space

scientific article published on 19 May 2020

Mechanistic Insight through Irreversible Inhibition: DNA Polymerase θ Uses a Common Active Site for Polymerase and Lyase Activities

artículo científico publicado en 2018

Mutagenic Effects of a 2-Deoxyribonolactone-Thymine Glycol Tandem DNA Lesion in Human Cells

artículo científico publicado en 2019

Oxidation of 8-oxo-7,8-dihydro-2'-deoxyguanosine leads to substantial DNA-histone cross-links within nucleosome core particles

scientific article published on 19 November 2018

Positional Dependence of DNA Hole Transfer Efficiency in Nucleosome Core Particles

artículo científico publicado en 2019

Probing Enhanced Double-Strand Break Formation at Abasic Sites within Clustered Lesions in Nucleosome Core Particles.

artículo científico publicado en 2016

Reactivity of N3-Methyl-2'-Deoxyadenosine in Nucleosome Core Particles

artículo científico publicado en 2019

Reactivity of the Major Product of C5'-Oxidative DNA Damage in Nucleosome Core Particles

scientific article published on 10 January 2019

Recommendations for standardized description of and nomenclature concerning oxidatively damaged nucleobases in DNA.

artículo científico publicado en 2010

Rotational Effects within Nucleosome Core Particles on Abasic Site Reactivity

artículo científico publicado en 2018

Synergistic Effects of an Irreversible DNA Polymerase Inhibitor and DNA Damaging Agents on HeLa Cells

artículo científico publicado en 2018

Synergistic Effects of an Irreversible DNA Polymerase Inhibitor and DNA Damaging Agents on HeLa Cells.

artículo científico publicado en 2017

Synthesis of 5-Methylene-2-pyrrolones

artículo científico publicado en 2018

Synthesis of Oligonucleotides Containing the N6 -(2-Deoxy-α,β-d-erythropentofuranosyl)-2,6-diamino-4-hydroxy-5-formamidopyrimidine (Fapy⋅dG) Oxidative Damage Product Derived from 2'-Deoxyguanosine

scientific article published on 09 April 2020

The A-Rule and Deletion Formation During Abasic and Oxidized Abasic Site Bypass by DNA Polymerase θ.

artículo científico publicado en 2017

Thiol Specific and Tracelessly Removable Bioconjugation via Michael Addition to 5-Methylene Pyrrolones.

artículo científico publicado en 2017

Traceless Tandem Lesion Formation in DNA from a Nitrogen-Centered Purine Radical

scientific article published on 08 May 2018