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18F-Branched-Chain Amino Acids: Structure-Activity Relationships and PET Imaging Potential

artículo científico publicado en 2019

18F-Fluorination of Unactivated C-H Bonds in Branched Aliphatic Amino Acids: Direct Synthesis of Oncological Positron Emission Tomography Imaging Agents.

artículo científico publicado en 2017

2 H-1,2,3-Triazole-Based Dipeptidyl Nitriles: Potent, Selective, and Trypanocidal Rhodesain Inhibitors by Structure-Based Design

artículo científico publicado en 2018

2‐Phenoxy‐nicotinamides are Potent Agonists at the Bile Acid Receptor GPBAR1 (TGR5)

artículo científico publicado el 7 de diciembre de 2012

A Convenient Late-Stage Fluorination of Pyridylic C-H Bonds with N-Fluorobenzenesulfonimide.

artículo científico publicado en 2016

A Convenient Synthesis of Difluoroalkyl Ethers from Thionoesters Using Silver(I) Fluoride

scientific article published on 19 September 2019

A convenient photocatalytic fluorination of unactivated C-H bonds.

artículo científico publicado en 2014

CHEMICAL SYNTHESIS. Going with the flow.

artículo científico publicado en 2016

Determination of End-to-End Distances in a Series of TEMPO Diradicals of up to 2.8 nm Length with a New Four-Pulse Double Electron Electron Resonance Experiment

artículo científico publicado en 1998

Direct heterobenzylic fluorination, difluorination and trifluoromethylthiolation with dibenzenesulfonamide derivatives.

artículo científico publicado en 2018

Discovery and optimisation of 1-hydroxyimino-3,3-diphenylpropanes, a new class of orally active GPBAR1 (TGR5) agonists

artículo científico publicado el 19 de junio de 2013

Discovery of novel and orally active FXR agonists for the potential treatment of dyslipidemia & diabetes

artículo científico publicado el 12 de noviembre de 2010

Inverse Electron-Demand [4 + 2]-Cycloadditions of Ynamides: Access to Novel Pyridine Scaffolds

article

Linear Monodisperse π-Conjugated Oligomers: Model Compounds for Polymers and More

scientific article published on 01 May 1999

Modulation of Pharmacologically Relevant Properties of Piperidine Derivatives by Functional Groups in an Equatorial or Axial β-Position to the Amino Group

artículo científico publicado en 2019

Monodisperse Poly(triacetylene) Rods: Synthesis of a 11.9 nm Long Molecular Wire and Direct Determination of the Effective Conjugation Length by UV/Vis and Raman Spectroscopies

artículo científico publicado en 1999

Optimization of a novel class of benzimidazole-based farnesoid X receptor (FXR) agonists to improve physicochemical and ADME properties

artículo científico publicado el 31 de diciembre de 2010

Paracrine crosstalk between intestinal L- and D-cells controls secretion of glucagon-like peptide-1 in mice

artículo científico publicado en 2019

Prospective Evaluation of Free Energy Calculations for the Prioritization of Cathepsin L Inhibitors.

artículo científico publicado en 2017

Quaternary Ammonium Trifluoromethoxide Salts as Stable Sources of Nucleophilic OCF3

artículo científico publicado en 2020

Seamless integration of dose-response screening and flow chemistry: efficient generation of structure-activity relationship data of β-secretase (BACE1) inhibitors

artículo científico publicado en 2014

Site-Selective, Late-Stage C-H 18 F-Fluorination on Unprotected Peptides for Positron Emission Tomography Imaging

scientific article published on 05 September 2018

Synthesis of acyl fluorides via photocatalytic fluorination of aldehydic C-H bonds

scientific article published on 20 August 2018

Synthesis of annulated pyridines as inhibitors of aldosterone synthase (CYP11B2)

artículo científico publicado en 2016

The Kondrat’eva Reaction in Flow: Direct Access to Annulated Pyridines

artículo científico publicado el 27 de junio de 2013