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A Pan-Cancer Analysis Reveals High-Frequency Genetic Alterations in Mediators of Signaling by the TGF-β Superfamily

artículo científico publicado en 2018

A murine preclinical syngeneic transplantation model for breast cancer precision medicine.

artículo científico publicado en 2017

Adipose tissue-specific ablation of Ces1d causes metabolic dysregulation in mice

artículo científico publicado en 2022

Amino acid metabolism in hematologic malignancies and the era of targeted therapy

artículo científico publicado en 2019

CD38-Mediated Immunosuppression as a Mechanism of Tumor Cell Escape from PD-1/PD-L1 Blockade

artículo científico publicado en 2018

Enteral Activation of WR-2721 Mediates Radioprotection and Improved Survival from Lethal Fractionated Radiation

artículo científico publicado en 2019

GPR1 and CMKLR1 control lipid metabolism to support development of clear cell renal cell carcinoma

artículo científico publicado en 2024

Glutaminase Activity of L-Asparaginase Contributes to Durable Preclinical Activity against Acute Lymphoblastic Leukemia

scientific article published on 17 June 2019

Inhibition of mitochondrial complex I reverses NOTCH1-driven metabolic reprogramming in T-cell acute lymphoblastic leukemia

artículo científico publicado en 2022

Interfering with lipid metabolism through targeting CES1 sensitizes hepatocellular carcinoma for chemotherapy

artículo científico publicado en 2023

Mechanism of Catalysis by l-Asparaginase

artículo científico publicado en 2020

Medium-Chain Acyl-CoA Dehydrogenase Protects Mitochondria from Lipid Peroxidation in Glioblastoma

artículo científico publicado en 2021

Metabolic reprogramming toward oxidative phosphorylation identifies a therapeutic target for mantle cell lymphoma

scientific article published on 01 May 2019

The glutaminase activity of L-asparaginase is not required for anticancer activity against ASNS-negative cells.

artículo científico publicado en 2014

The glutaminase inhibitor CB-839 (Telaglenastat) enhances the anti-melanoma activity of T cell mediated immunotherapies

scientific article published on 23 December 2020

Vestigial-like 1 is a shared targetable cancer-placenta antigen expressed by pancreatic and basal-like breast cancers

artículo científico publicado en 2020