Lista de obras -

"Soluble" adenylyl cyclase-generated cyclic adenosine monophosphate promotes fast migration in PC12 cells

artículo científico publicado en 2008

A mitochondrial CO2-adenylyl cyclase-cAMP signalosome controls yeast normoxic cytochrome c oxidase activity

artículo científico publicado en 2014

A novel mechanism for adenylyl cyclase inhibition from the crystal structure of its complex with catechol estrogen

artículo científico publicado en 2005

A phosphodiesterase 2A isoform localized to mitochondria regulates respiration

scientific journal article

A soluble adenylyl cyclase form targets to axonemes and rescues beat regulation in soluble adenylyl cyclase knockout mice

artículo científico publicado en 2014

Activation of soluble adenylyl cyclase protects against secretagogue stimulated zymogen activation in rat pancreaic acinar cells

artículo científico publicado en 2012

Autoinhibitory regulation of soluble adenylyl cyclase

artículo científico publicado en 2006

Bicarbonate activation of adenylyl cyclase via promotion of catalytic active site closure and metal recruitment

artículo científico publicado en 2004

Bicarbonate-regulated Adenylyl Cyclase (sAC) Is a Sensor That Regulates pH-dependent V-ATPase Recycling ⬇️

artículo científico publicado el 25 de septiembre de 2003

Bicarbonate-responsive "soluble" adenylyl cyclase defines a nuclear cAMP microdomain

artículo científico publicado en 2004

Bicarbonate-sensing soluble adenylyl cyclase is an essential sensor for acid/base homeostasis

artículo científico publicado en 2009

Bithionol Potently Inhibits Human Soluble Adenylyl Cyclase through Binding to the Allosteric Activator Site

artículo científico publicado en 2016

CO(2) acts as a signalling molecule in populations of the fungal pathogen Candida albicans

artículo científico publicado en 2010

CO2/HCO3(-)- and calcium-regulated soluble adenylyl cyclase as a physiological ATP sensor

artículo científico publicado en 2013

CO2/HCO3−- and calcium-regulated soluble adenylyl cyclase as a physiological ATP sensor

artículo científico publicado en 2014

Calcium-sensing soluble adenylyl cyclase mediates TNF signal transduction in human neutrophils

artículo científico publicado en 2005

Characterization of Plasmodium falciparum adenylyl cyclase-β and its role in erythrocytic stage parasites

artículo científico publicado en 2012

Compartmentalization of bicarbonate-sensitive adenylyl cyclase in distinct signaling microdomains

artículo científico publicado en 2002

Compartmentalization of distinct cAMP signaling pathways in mammalian sperm

scientific article published on 15 October 2013

Conservation of functional domain structure in bicarbonate-regulated "soluble" adenylyl cyclases in bacteria and eukaryotes

artículo científico publicado en 2004

Cryptococcus neoformans senses CO2 through the carbonic anhydrase Can2 and the adenylyl cyclase Cac1

artículo científico publicado en 2006

Crystal Structure and Regulation Mechanisms of the CyaB Adenylyl Cyclase from the Human Pathogen Pseudomonas aeruginosa

artículo científico publicado en 2012

Crystal structures of human soluble adenylyl cyclase reveal mechanisms of catalysis and of its activation through bicarbonate

artículo científico publicado en 2014

Cyclic AMP produced inside mitochondria regulates oxidative phosphorylation

artículo científico publicado en 2009

Differential Intraocular Pressure Measurements by Tonometry and Direct Cannulation After Treatment with Soluble Adenylyl Cyclase Inhibitors

artículo científico publicado en 2017

Discovery of LRE1 as a specific and allosteric inhibitor of soluble adenylyl cyclase.

artículo científico publicado en 2016

Distinct intracellular sAC-cAMP domains regulate ER Ca2+ signaling and OXPHOS function.

artículo científico publicado en 2017

Endothelial CD99 signals through soluble adenylyl cyclase and PKA to regulate leukocyte transendothelial migration

artículo científico publicado en 2015

Fungal Adenylyl Cyclase Integrates CO2 Sensing with cAMP Signaling and Virulence

Fungal adenylyl cyclase integrates CO2 sensing with cAMP signaling and virulence

artículo científico publicado en 2005

Gastric inhibitory peptide controls adipose insulin sensitivity via activation of cAMP-response element-binding protein and p110β isoform of phosphatidylinositol 3-kinase

artículo científico publicado en 2011

Glucose and GLP-1 stimulate cAMP production via distinct adenylyl cyclases in INS-1E insulinoma cells

artículo científico publicado en 2008

HCO(3)(-)-dependent soluble adenylyl cyclase activates cystic fibrosis transmembrane conductance regulator in corneal endothelium

artículo científico publicado en 2003

Identification of a haem domain in human soluble adenylate cyclase

artículo científico publicado en 2012

Intracellular cAMP signaling by soluble adenylyl cyclase.

artículo científico publicado en 2011

Kinetic properties of "soluble" adenylyl cyclase. Synergism between calcium and bicarbonate

artículo científico publicado en 2003

Mammalian pigmentation is regulated by a distinct cAMP-dependent mechanism that controls melanosome pH

artículo científico publicado en 2018

Metabolic communication between astrocytes and neurons via bicarbonate-responsive soluble adenylyl cyclase

artículo científico publicado en 2012

Modulation of NaCl absorption by [HCO(3)(-)] in the marine teleost intestine is mediated by soluble adenylyl cyclase

artículo científico publicado en 2010

Molecular details of cAMP generation in mammalian cells: a tale of two systems

artículo científico publicado en 2006

Neuronal expression of soluble adenylyl cyclase in the mammalian brain

artículo científico publicado en 2013

Nonpigmented ciliary epithelial cells respond to acetazolamide by a soluble adenylyl cyclase mechanism

artículo científico publicado en 2014

Particulate and soluble adenylyl cyclases participate in the sperm acrosome reaction

artículo científico publicado en 2007

Pharmacological distinction between soluble and transmembrane adenylyl cyclases

artículo científico publicado en 2013

Pharmacological modulation of the CO2/HCO3-/pH-, calcium-, and ATP-sensing soluble adenylyl cyclase

scientific article published on 26 May 2018

Physiological carbon dioxide, bicarbonate, and pH sensing

artículo científico publicado en 2010

Physiological roles of acid-base sensors

artículo científico publicado en 2014

Physiological sensing of carbon dioxide/bicarbonate/pH via cyclic nucleotide signaling

artículo científico publicado en 2011

Purification of soluble adenylyl cyclase

artículo científico publicado en 2002

Regulation of anterior chamber drainage by bicarbonate-sensitive soluble adenylyl cyclase in the ciliary body

artículo científico publicado en 2011

Regulation of epithelial Na+ transport by soluble adenylyl cyclase in kidney collecting duct cells

artículo científico publicado en 2009

Role of soluble adenylyl cyclase in the heart

artículo científico publicado en 2011

Soluble adenylyl cyclase defines a nuclear cAMP microdomain in keratinocyte hyperproliferative skin diseases

artículo científico publicado en 2010

Soluble adenylyl cyclase is essential for proper lysosomal acidification

artículo científico publicado en 2016

Soluble adenylyl cyclase is localized to cilia and contributes to ciliary beat frequency regulation via production of cAMP

artículo científico publicado en 2007

Soluble adenylyl cyclase is necessary and sufficient to overcome the block of axonal growth by myelin-associated factors.

artículo científico publicado en 2014

Soluble adenylyl cyclase is required for netrin-1 signaling in nerve growth cones

scientific journal article

Soluble adenylyl cyclase mediates nerve growth factor-induced activation of Rap1

scientific journal article

Somatic 'soluble' adenylyl cyclase isoforms are unaffected in Sacy tm1Lex/Sacy tm1Lex 'knockout' mice

artículo científico publicado en 2008

Specific expression of soluble adenylyl cyclase in male germ cells

scientific article published in 2000

Structure-based development of novel adenylyl cyclase inhibitors

artículo científico publicado en 2008

The "soluble" adenylyl cyclase in sperm mediates multiple signaling events required for fertilization

artículo científico publicado en 2005

The metabolic/pH sensor soluble adenylyl cyclase is a tumor suppressor protein

artículo científico publicado en 2016

The quorum-sensing molecules farnesol/homoserine lactone and dodecanol operate via distinct modes of action in Candida albicans

artículo científico publicado en 2011

The role of soluble adenylyl cyclase in health and disease

article

The soluble guanylyl cyclase activator YC-1 increases intracellular cGMP and cAMP via independent mechanisms in INS-1E cells

artículo científico publicado en 2011

Transient exposure to calcium ionophore enables in vitro fertilization in sterile mouse models

artículo científico publicado en 2016

cAMP and mitochondria

artículo científico publicado en 2013

pH sensing via bicarbonate-regulated "soluble" adenylyl cyclase (sAC)

artículo científico publicado en 2013

Lista de obras de

"Soluble" adenylyl cyclase-generated cyclic adenosine monophosphate promotes fast migration in PC12 cells

A mitochondrial CO2-adenylyl cyclase-cAMP signalosome controls yeast normoxic cytochrome c oxidase activity

A novel mechanism for adenylyl cyclase inhibition from the crystal structure of its complex with catechol estrogen

A phosphodiesterase 2A isoform localized to mitochondria regulates respiration

A soluble adenylyl cyclase form targets to axonemes and rescues beat regulation in soluble adenylyl cyclase knockout mice

Activation of soluble adenylyl cyclase protects against secretagogue stimulated zymogen activation in rat pancreaic acinar cells

Autoinhibitory regulation of soluble adenylyl cyclase

Bicarbonate activation of adenylyl cyclase via promotion of catalytic active site closure and metal recruitment

Bicarbonate-regulated Adenylyl Cyclase (sAC) Is a Sensor That Regulates pH-dependent V-ATPase Recycling ⬇️

Bicarbonate-responsive "soluble" adenylyl cyclase defines a nuclear cAMP microdomain

Bicarbonate-sensing soluble adenylyl cyclase is an essential sensor for acid/base homeostasis

Bithionol Potently Inhibits Human Soluble Adenylyl Cyclase through Binding to the Allosteric Activator Site

CO(2) acts as a signalling molecule in populations of the fungal pathogen Candida albicans

CO2/HCO3(-)- and calcium-regulated soluble adenylyl cyclase as a physiological ATP sensor

CO2/HCO3−- and calcium-regulated soluble adenylyl cyclase as a physiological ATP sensor

Calcium-sensing soluble adenylyl cyclase mediates TNF signal transduction in human neutrophils

Characterization of Plasmodium falciparum adenylyl cyclase-β and its role in erythrocytic stage parasites

Compartmentalization of bicarbonate-sensitive adenylyl cyclase in distinct signaling microdomains

Compartmentalization of distinct cAMP signaling pathways in mammalian sperm

Conservation of functional domain structure in bicarbonate-regulated "soluble" adenylyl cyclases in bacteria and eukaryotes

Cryptococcus neoformans senses CO2 through the carbonic anhydrase Can2 and the adenylyl cyclase Cac1

Crystal Structure and Regulation Mechanisms of the CyaB Adenylyl Cyclase from the Human Pathogen Pseudomonas aeruginosa

Crystal structures of human soluble adenylyl cyclase reveal mechanisms of catalysis and of its activation through bicarbonate

Cyclic AMP produced inside mitochondria regulates oxidative phosphorylation

Differential Intraocular Pressure Measurements by Tonometry and Direct Cannulation After Treatment with Soluble Adenylyl Cyclase Inhibitors

Discovery of LRE1 as a specific and allosteric inhibitor of soluble adenylyl cyclase.

Distinct intracellular sAC-cAMP domains regulate ER Ca2+ signaling and OXPHOS function.

Endothelial CD99 signals through soluble adenylyl cyclase and PKA to regulate leukocyte transendothelial migration

Fungal Adenylyl Cyclase Integrates CO2 Sensing with cAMP Signaling and Virulence

Fungal adenylyl cyclase integrates CO2 sensing with cAMP signaling and virulence

Gastric inhibitory peptide controls adipose insulin sensitivity via activation of cAMP-response element-binding protein and p110β isoform of phosphatidylinositol 3-kinase

Glucose and GLP-1 stimulate cAMP production via distinct adenylyl cyclases in INS-1E insulinoma cells

HCO(3)(-)-dependent soluble adenylyl cyclase activates cystic fibrosis transmembrane conductance regulator in corneal endothelium

Identification of a haem domain in human soluble adenylate cyclase

Intracellular cAMP signaling by soluble adenylyl cyclase.

Kinetic properties of "soluble" adenylyl cyclase. Synergism between calcium and bicarbonate

Mammalian pigmentation is regulated by a distinct cAMP-dependent mechanism that controls melanosome pH

Metabolic communication between astrocytes and neurons via bicarbonate-responsive soluble adenylyl cyclase

Modulation of NaCl absorption by [HCO(3)(-)] in the marine teleost intestine is mediated by soluble adenylyl cyclase

Molecular details of cAMP generation in mammalian cells: a tale of two systems

Neuronal expression of soluble adenylyl cyclase in the mammalian brain

Nonpigmented ciliary epithelial cells respond to acetazolamide by a soluble adenylyl cyclase mechanism

Particulate and soluble adenylyl cyclases participate in the sperm acrosome reaction

Pharmacological distinction between soluble and transmembrane adenylyl cyclases

Pharmacological modulation of the CO2/HCO3-/pH-, calcium-, and ATP-sensing soluble adenylyl cyclase

Physiological carbon dioxide, bicarbonate, and pH sensing

Physiological roles of acid-base sensors

Physiological sensing of carbon dioxide/bicarbonate/pH via cyclic nucleotide signaling

Purification of soluble adenylyl cyclase

Regulation of anterior chamber drainage by bicarbonate-sensitive soluble adenylyl cyclase in the ciliary body

Regulation of epithelial Na+ transport by soluble adenylyl cyclase in kidney collecting duct cells

Role of soluble adenylyl cyclase in the heart

Soluble adenylyl cyclase defines a nuclear cAMP microdomain in keratinocyte hyperproliferative skin diseases

Soluble adenylyl cyclase is essential for proper lysosomal acidification

Soluble adenylyl cyclase is localized to cilia and contributes to ciliary beat frequency regulation via production of cAMP

Soluble adenylyl cyclase is necessary and sufficient to overcome the block of axonal growth by myelin-associated factors.

Soluble adenylyl cyclase is required for netrin-1 signaling in nerve growth cones

Soluble adenylyl cyclase mediates nerve growth factor-induced activation of Rap1

Somatic 'soluble' adenylyl cyclase isoforms are unaffected in Sacy tm1Lex/Sacy tm1Lex 'knockout' mice

Specific expression of soluble adenylyl cyclase in male germ cells

Structure-based development of novel adenylyl cyclase inhibitors

The "soluble" adenylyl cyclase in sperm mediates multiple signaling events required for fertilization

The metabolic/pH sensor soluble adenylyl cyclase is a tumor suppressor protein

The quorum-sensing molecules farnesol/homoserine lactone and dodecanol operate via distinct modes of action in Candida albicans

The role of soluble adenylyl cyclase in health and disease

The soluble guanylyl cyclase activator YC-1 increases intracellular cGMP and cAMP via independent mechanisms in INS-1E cells

Transient exposure to calcium ionophore enables in vitro fertilization in sterile mouse models

cAMP and mitochondria

pH sensing via bicarbonate-regulated "soluble" adenylyl cyclase (sAC)