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Activating somatic mutations outside the SH2-domain of STAT3 in LGL leukemia

artículo científico publicado en 2015

Aggressive natural killer-cell leukemia mutational landscape and drug profiling highlight JAK-STAT signaling as therapeutic target.

artículo científico publicado en 2018

Idelalisib sensitivity and mechanisms of disease progression in relapsed TCF3-PBX1 acute lymphoblastic leukemia

artículo científico publicado en 2016

Identification of precision treatment strategies for relapsed/refractory multiple myeloma by functional drug sensitivity testing

artículo científico publicado en 2017

In silico and preclinical drug screening identifies dasatinib as a targeted therapy for T-ALL.

artículo científico publicado en 2017

Novel activating STAT5B mutations as putative drivers of T-cell acute lymphoblastic leukemia

artículo científico publicado en 2014

Novel drug candidates for blast phase chronic myeloid leukemia from high-throughput drug sensitivity and resistance testing

artículo científico publicado en 2015

Phenotype-based drug screening reveals association between venetoclax response and differentiation stage in acute myeloid leukemia

scientific article published on 11 July 2019

Reinstated p53 response and high anti-T-cell leukemia activity by the novel alkylating deacetylase inhibitor tinostamustine

artículo científico publicado en 2020

Selective drug combination vulnerabilities in STAT3- and TP53-mutant malignant NK cells

artículo científico publicado en 2021

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