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A Flp-SUMO hybrid recombinase reveals multi-layered copy number control of a selfish DNA element through post-translational modification

scientific article published on 26 June 2019

A single nuclease-resistant linkage in DNA as a versatile tool for the characterization of DNA lesions: application to the guanine oxidative lesion "G+34" generated by metalloporphyrin/KHSO(5) reagent

Active site electrostatics protect genome integrity by blocking abortive hydrolysis during DNA recombination.

artículo científico publicado en 2009

An Overview of Tyrosine Site-specific Recombination: From an Flp Perspective

artículo científico

Antagonists of Vitamin K-Popular Coumarin Drugs and New Synthetic and Natural Coumarin Derivatives

scientific article published on 24 March 2020

Antimicrobial and structural properties of metal ions complexes with thiosemicarbazide motif and related heterocyclic compounds.

artículo científico publicado en 2018

Binding of phosphorothioate oligodeoxynucleotides to basic fibroblast growth factor, recombinant soluble CD4, laminin and fibronectin is P-chirality independent

artículo científico publicado en 1995

Blood serum and neutrophil L-arginine concentrations and nitric oxide release by neutrophils in chronic uremic patients and healthy persons

artículo científico publicado en 2003

Blood serum and neutrophil amino acid concentrations during hemodialysis

artículo científico publicado en 2005

Comparison of the cleavage profiles of oligonucleotide duplexes with or without phosphorothioate linkages by using a chemical nuclease probe.

artículo científico

Diastereomerically pure nucleoside‐5′‐O‐(2‐thio‐4,4‐pentamethylene‐1,3,2‐oxathiaphospholane)s—Substrates for synthesis of P‐chiral derivatives of nucleoside‐5′‐O‐phosphorothioates ⬇️

artículo científico publicado el 6 de octubre de 2010

Diastereomers of thymidine 3'-O-(methanephosphonothioate): synthesis, absolute configuration and reaction with 3'-methoxyacetylthymidine under conditions of triester approach to oligonucleotide synthesis

artículo científico publicado en 1987

Dynamic NMR Structures of [Rp]- and [Sp]-Phosphorothioated DNA-RNA Hybrids: Is Flexibility Required for RNase H Recognition? ⬇️

artículo científico publicado el 1 de octubre de 2003

Effect of P-chirality of internucleotide bonds on B-Z conversion of stereodefined self-complementary phosphorothioate oligonucleotides of the [PS]-d(CG)4 and [PS]-d(GC)4 series

artículo científico publicado en 2000

Electrostatic suppression allows tyrosine site-specific recombination in the absence of a conserved catalytic arginine

artículo científico publicado en 2010

Guanosine in a single stranded region of anticodon stem-loop tRNA models is prone to oxidatively generated damage resulting in dehydroguanidinohydantoin and spiroiminodihydantoin lesions

artículo científico publicado en 2015

Homopurine RP-stereodefined phosphorothioate analogs of DNA with hampered Watson-Crick base pairings form Hoogsteen paired parallel duplexes with (2'-OMe)-RNAs

artículo científico publicado en 2019

Hoogsteen-paired homopurine [RP-PS]-DNA and homopyrimidine RNA strands form a thermally stable parallel duplex

artículo científico publicado en 2007

Inhibition of Potentially Anti-Apoptotic Proteins by Antisense Protein Kinase C-α (Isis 3521) and Antisense bcl-2 (G3139) Phosphorothioate Oligodeoxynucleotides: Relationship to the Decreased Viability of T24 Bladder and PC3 Prostate Cancer Cells ⬇️

artículo científico publicado el 1 de diciembre de 2001

Inhibition of human immunodeficiency virus type 1 replication by P-stereodefined oligo(nucleoside phosphorothioate)s in a long-term infection model

artículo científico publicado en 2002

LNA units present in the (2'-OMe)-RNA strand stabilize parallel duplexes (2'-OMe)-RNA/[All-R(P)-PS]-DNA and parallel triplexes (2'-OMe)-RNA/[All-R(P)-PS]-DNA/RNA. An improved tool for the inhibition of reverse transcription

artículo científico publicado en 2015

Oxathiaphospholane Approach to the Synthesis of P-Chiral, Isotopomeric Deoxy(ribonucleoside phosphorothioate)s and Phosphates Labeled with an Oxygen Isotope

Oxathiaphospholane Approach to the Synthesis of P-Chiral, Isotopomeric Deoxy(ribonucleoside phosphorothioate)s and Phosphates Labeled with an Oxygen Isotope This work was financially supported by the State Committee for Scientific Research (KBN, Pol

artículo científico publicado en 2001

Oxathiaphospholane approach to the synthesis of oligodeoxyribonucleotides containing stereodefined internucleotide phosphoroselenoate function

artículo científico publicado en 2005

P-chiral oligonucleotides in biological recognition processes

artículo científico publicado en 2007

P-chirality-dependent immune activation by phosphorothioate CpG oligodeoxynucleotides

artículo científico publicado en 2003

Phosphorothioate nucleotides and oligonucleotides - recent progress in synthesis and application

artículo científico publicado el 1 de septiembre de 2011

Reactions of Cre with methylphosphonate DNA: similarities and contrasts with Flp and vaccinia topoisomerase

artículo científico publicado en 2009

Restoration of catalytic functions in Cre recombinase mutants by electrostatic compensation between active site and DNA substrate.

artículo científico publicado en 2010

Retention of configuration in the action of human plasma 3'-exonuclease on oligo(deoxynucleoside phosphorothioate). A new method for assignment of absolute configuration at phosphorus in isotopomeric deoxyadenosine 5'-O-[(18)O]phosphorothioate.

artículo científico publicado en 2002

Stability of stereoregular oligo(nucleoside phosphorothioate)s in human plasma: diastereoselectivity of plasma 3'-exonuclease

artículo científico publicado en 1997

Stereochemistry of cleavage of internucleotide bonds by Serratia marcescens endonuclease

artículo científico publicado en 2001

Stereodefined phosphorothioate analogues of DNA: relative thermodynamic stability of the model PS-DNA/DNA and PS-DNA/RNA complexes

scientific article published on 01 October 2002

Stereoselective formation of a P–P bond in the reaction of 2-alkoxy-2-thio-1,3,2-oxathiaphospholanes with O,O-dialkyl H-phosphonates and H-thiophosphonates ⬇️

artículo científico publicado el 14 de octubre de 2010

Stereospecific suppression of active site mutants by methylphosphonate substituted substrates reveals the stereochemical course of site-specific DNA recombination.

artículo científico publicado en 2015

Synthesis and expression in E. coli of the gene for human tumor necrosis factor (h alpha TNF)

artículo científico publicado el 1 de enero de 1991

Synthesis of phosphorothioate oligonucleotides with stereodefined phosphorothioate linkages

artículo científico publicado en 2003

The effect of tumour necrosis factor-alpha (TNF-alpha) muteins on human neutrophils in vitro

artículo científico publicado en 1993

The effects of tumor necrosis factor (TNF) derivatives on TNF receptors

artículo científico publicado en 1993

The immunoregulatory granulocyte factor (GF). III. Characteristics of target cells for GF

scientific article published on 01 March 1994

Thermal stability and conformation of antiparallel duplexes formed by P-stereodefined phosphorothioate DNA/LNA chimeric oligomers with DNA and RNA matrices.

artículo científico publicado en 2015

Unexpected loss of stereoselectivity in ring-opening reaction of 2-alkoxy-2-thio-1,3,2-oxathiaphospholanes with a pyrophosphate anion

artículo científico publicado en 2014

Unusual thermal stability of RNA/[RP-PS]-DNA/RNA triplexes containing a homopurine DNA strand

artículo científico publicado en 2007

Lista de obras de

A Flp-SUMO hybrid recombinase reveals multi-layered copy number control of a selfish DNA element through post-translational modification

A single nuclease-resistant linkage in DNA as a versatile tool for the characterization of DNA lesions: application to the guanine oxidative lesion "G+34" generated by metalloporphyrin/KHSO(5) reagent

Active site electrostatics protect genome integrity by blocking abortive hydrolysis during DNA recombination.

An Overview of Tyrosine Site-specific Recombination: From an Flp Perspective

Antagonists of Vitamin K-Popular Coumarin Drugs and New Synthetic and Natural Coumarin Derivatives

Antimicrobial and structural properties of metal ions complexes with thiosemicarbazide motif and related heterocyclic compounds.

Binding of phosphorothioate oligodeoxynucleotides to basic fibroblast growth factor, recombinant soluble CD4, laminin and fibronectin is P-chirality independent

Blood serum and neutrophil L-arginine concentrations and nitric oxide release by neutrophils in chronic uremic patients and healthy persons

Blood serum and neutrophil amino acid concentrations during hemodialysis

Comparison of the cleavage profiles of oligonucleotide duplexes with or without phosphorothioate linkages by using a chemical nuclease probe.

Diastereomerically pure nucleoside‐5′‐O‐(2‐thio‐4,4‐pentamethylene‐1,3,2‐oxathiaphospholane)s—Substrates for synthesis of P‐chiral derivatives of nucleoside‐5′‐O‐phosphorothioates ⬇️

Diastereomers of thymidine 3'-O-(methanephosphonothioate): synthesis, absolute configuration and reaction with 3'-methoxyacetylthymidine under conditions of triester approach to oligonucleotide synthesis

Dynamic NMR Structures of [Rp]- and [Sp]-Phosphorothioated DNA-RNA Hybrids: Is Flexibility Required for RNase H Recognition? ⬇️

Effect of P-chirality of internucleotide bonds on B-Z conversion of stereodefined self-complementary phosphorothioate oligonucleotides of the [PS]-d(CG)4 and [PS]-d(GC)4 series

Electrostatic suppression allows tyrosine site-specific recombination in the absence of a conserved catalytic arginine

Guanosine in a single stranded region of anticodon stem-loop tRNA models is prone to oxidatively generated damage resulting in dehydroguanidinohydantoin and spiroiminodihydantoin lesions

Homopurine RP-stereodefined phosphorothioate analogs of DNA with hampered Watson-Crick base pairings form Hoogsteen paired parallel duplexes with (2'-OMe)-RNAs

Hoogsteen-paired homopurine [RP-PS]-DNA and homopyrimidine RNA strands form a thermally stable parallel duplex

Inhibition of Potentially Anti-Apoptotic Proteins by Antisense Protein Kinase C-α (Isis 3521) and Antisense bcl-2 (G3139) Phosphorothioate Oligodeoxynucleotides: Relationship to the Decreased Viability of T24 Bladder and PC3 Prostate Cancer Cells ⬇️

Inhibition of human immunodeficiency virus type 1 replication by P-stereodefined oligo(nucleoside phosphorothioate)s in a long-term infection model

LNA units present in the (2'-OMe)-RNA strand stabilize parallel duplexes (2'-OMe)-RNA/[All-R(P)-PS]-DNA and parallel triplexes (2'-OMe)-RNA/[All-R(P)-PS]-DNA/RNA. An improved tool for the inhibition of reverse transcription

Oxathiaphospholane Approach to the Synthesis of P-Chiral, Isotopomeric Deoxy(ribonucleoside phosphorothioate)s and Phosphates Labeled with an Oxygen Isotope

Oxathiaphospholane Approach to the Synthesis of P-Chiral, Isotopomeric Deoxy(ribonucleoside phosphorothioate)s and Phosphates Labeled with an Oxygen Isotope This work was financially supported by the State Committee for Scientific Research (KBN, Pol

Oxathiaphospholane approach to the synthesis of oligodeoxyribonucleotides containing stereodefined internucleotide phosphoroselenoate function

P-chiral oligonucleotides in biological recognition processes

P-chirality-dependent immune activation by phosphorothioate CpG oligodeoxynucleotides

Phosphorothioate nucleotides and oligonucleotides - recent progress in synthesis and application

Reactions of Cre with methylphosphonate DNA: similarities and contrasts with Flp and vaccinia topoisomerase

Restoration of catalytic functions in Cre recombinase mutants by electrostatic compensation between active site and DNA substrate.

Retention of configuration in the action of human plasma 3'-exonuclease on oligo(deoxynucleoside phosphorothioate). A new method for assignment of absolute configuration at phosphorus in isotopomeric deoxyadenosine 5'-O-[(18)O]phosphorothioate.

Stability of stereoregular oligo(nucleoside phosphorothioate)s in human plasma: diastereoselectivity of plasma 3'-exonuclease

Stereochemistry of cleavage of internucleotide bonds by Serratia marcescens endonuclease

Stereodefined phosphorothioate analogues of DNA: relative thermodynamic stability of the model PS-DNA/DNA and PS-DNA/RNA complexes

Stereoselective formation of a P–P bond in the reaction of 2-alkoxy-2-thio-1,3,2-oxathiaphospholanes with O,O-dialkyl H-phosphonates and H-thiophosphonates ⬇️

Stereospecific suppression of active site mutants by methylphosphonate substituted substrates reveals the stereochemical course of site-specific DNA recombination.

Synthesis and expression in E. coli of the gene for human tumor necrosis factor (h alpha TNF)

Synthesis of phosphorothioate oligonucleotides with stereodefined phosphorothioate linkages

The effect of tumour necrosis factor-alpha (TNF-alpha) muteins on human neutrophils in vitro

The effects of tumor necrosis factor (TNF) derivatives on TNF receptors

The immunoregulatory granulocyte factor (GF). III. Characteristics of target cells for GF

Thermal stability and conformation of antiparallel duplexes formed by P-stereodefined phosphorothioate DNA/LNA chimeric oligomers with DNA and RNA matrices.

Unexpected loss of stereoselectivity in ring-opening reaction of 2-alkoxy-2-thio-1,3,2-oxathiaphospholanes with a pyrophosphate anion

Unusual thermal stability of RNA/[RP-PS]-DNA/RNA triplexes containing a homopurine DNA strand