Lista de obras -

2D hybrid analysis: Approach for building three-dimensional atomic model by electron microscopy image matching.

artículo científico publicado en 2017

A multipurpose fusion tag derived from an unstructured and hyperacidic region of the amyloid precursor protein ⬇️

artículo científico publicado el 29 de abril de 2013

A murine monoclonal antibody that binds N-terminal extracellular segment of human protease-activated receptor-4.

artículo científico publicado en 2008

A point mutation in Semaphorin 4A associates with defective endosomal sorting and causes retinal degeneration.

artículo científico publicado en 2013

A rapid screening method for cell lines producing singly-tagged recombinant proteins using the "TARGET tag" system

artículo científico publicado en 2010

A structure-based model of substrate discrimination by a noncanonical PDZ tandem in the intramembrane-cleaving protease RseP

artículo científico publicado en 2014

A systematic survey of conformational states in β1 and β4 integrins using negative-stain electron microscopy

artículo científico publicado en 2018

Active and water-soluble form of lipidated Wnt protein is maintained by a serum glycoprotein afamin/α-albumin.

artículo científico publicado en 2016

Advances in domain and subunit localization technology for electron microscopy

artículo científico publicado en 2019

Allosteric Inhibition of a Semaphorin 4D Receptor Plexin B1 by a High-Affinity Macrocyclic Peptide

artículo científico publicado en 2016

An anti-peptide monoclonal antibody recognizing the tobacco etch virus protease-cleavage sequence and its application to a tandem tagging system.

artículo científico publicado en 2018

Cellular signaling and gene expression profiles evoked by a bivalent macrocyclic peptide that serves as an artificial MET receptor agonist

artículo científico publicado en 2018

Clonal evolution and antigen recognition of anti-nuclear antibodies in acute systemic lupus erythematosus.

artículo científico publicado en 2017

Conformational Freedom of the LRP6 Ectodomain Is Regulated by N-glycosylation and the Binding of the Wnt Antagonist Dkk1.

artículo científico publicado en 2017

Corrigendum: Immune evasion of Plasmodium falciparum by RIFIN via inhibitory receptors

artículo científico publicado en 2018

Crystal structure of Enpp1, an extracellular glycoprotein involved in bone mineralization and insulin signaling

artículo científico publicado en 2012

Crystal structure of a mammalian Wnt-frizzled complex

artículo científico publicado en 2019

Crystal structure of autotaxin and insight into GPCR activation by lipid mediators

artículo científico publicado en 2011

Crystal structure of α5β1 integrin ectodomain: Atomic details of the fibronectin receptor ⬇️

artículo científico publicado el 26 de marzo de 2012

Crystal structures of the noncatalytic domains of ADAMTS13 reveal multiple discontinuous exosites for von Willebrand factor

artículo científico publicado en 2009

Crystallization and preliminary crystallographic analysis of human LR11 Vps10p domain.

artículo científico publicado en 2010

De novo peptide grafting to a self-assembling nanocapsule yields a hepatocyte growth factor receptor agonist

artículo científico publicado en 2021

Detection of endogenous LRP6 expressed on human cells by monoclonal antibodies specific for the native conformation.

artículo científico publicado en 2009

Development of a new protein labeling system to map subunits and domains of macromolecular complexes for electron microscopy.

artículo científico publicado en 2017

Development of a novel affinity tag system for the next generation structural biology

artículo científico publicado el 1 de septiembre de 2009

Development of cyclic peptides with potent in vivo osteogenic activity through RaPID-based affinity maturation

scientific article published on 23 November 2020

Distinct Localization of Mature HGF from its Precursor Form in Developing and Repairing the Stomach

scientific article published on 17 June 2019

Dynamic regulation of receptor transmembrane domain assembly during signal transmission across the plasma membrane

artículo científico publicado en 2005

Engineered ACE2 receptor therapy overcomes mutational escape of SARS-CoV-2

artículo científico publicado en 2021

Engineering ACE2 decoy receptors to combat viral escapability

artículo científico publicado en 2022

Expression, purification, crystallization and preliminary X-ray crystallographic analysis of Enpp1.

artículo científico publicado en 2012

Expression, purification, crystallization and preliminary X-ray crystallographic analysis of Enpp6.

artículo científico publicado en 2014

Facile Synthesis of Dimeric Thioether-Macrocyclic Peptides with Antibody-like Affinity against Plexin-B1

artículo científico publicado en 2018

First atomic view of alpha V beta 3 integrin extracellular domain

artículo científico publicado en 2002

Functional importance of covalent homodimer of reelin protein linked via its central region

artículo científico publicado en 2011

Functional role of the Frizzled linker domain in the Wnt signaling pathway

artículo científico publicado en 2022

Fv-clasp: An Artificially Designed Small Antibody Fragment with Improved Production Compatibility, Stability, and Crystallizability

artículo científico publicado en 2017

Higher-order architecture of cell adhesion mediated by polymorphic synaptic adhesion molecules neurexin and neuroligin

artículo científico publicado en 2012

Immune evasion of Plasmodium falciparum by RIFIN via inhibitory receptors

artículo científico publicado en 2017

Immunoaffinity Purification of the Glycosylated Extracellular Fragment of Mouse Plexin A2 Produced in a Mammalian Expression System

artículo científico publicado en 2017

Impaired ligand-dependent MET activation caused by an extracellular SEMA domain missense mutation in lung cancer

scientific article published on 13 August 2019

Interplay of Endosomal pH and Ligand Occupancy in Integrin α5β1 Ubiquitination, Endocytic Sorting, and Cell Migration

artículo científico publicado en 2015

Key interactions in integrin ectodomain responsible for global conformational change detected by elastic network normal-mode analysis

artículo científico publicado en 2008

Ligand-binding specificities of laminin-binding integrins: a comprehensive survey of laminin-integrin interactions using recombinant alpha3beta1, alpha6beta1, alpha7beta1 and alpha6beta4 integrins

artículo científico publicado en 2006

Loss of Parkinson's disease-associated protein CHCHD2 affects mitochondrial crista structure and destabilizes cytochrome c

artículo científico publicado en 2017

Lysosomal sorting of amyloid-β by the SORLA receptor is impaired by a familial Alzheimer's disease mutation

artículo científico publicado en 2014

Macrocyclic peptide-based inhibition and imaging of hepatocyte growth factor

artículo científico publicado en 2019

Mechanistic basis for the recognition of laminin-511 by α6β1 integrin.

artículo científico publicado en 2017

Mechanistic insights into ectodomain shedding: susceptibility of CADM1 adhesion molecule is determined by alternative splicing and O-glycosylation.

artículo científico publicado en 2017

Molecular Basis of the Ligand Binding Specificity of αvβ8 Integrin

artículo científico publicado en 2016

Molecular basis of the recognition of nephronectin by integrin alpha8beta1

scientific journal article

Negatively charged amino acids in the stalk region of membrane proteins reduce ectodomain shedding

artículo científico publicado en 2020

New era of structural analysis of proteins by electron microscopy-application to a dynamic structural analysis of integrin cell adhesion receptor-

artículo científico publicado en 2005

Novel affinity tag system using structurally defined antibody-tag interaction: Application to single-step protein purification

artículo científico publicado en 2008

Off-axis rotor in Enterococcus hirae V-ATPase visualized by Zernike phase plate single-particle cryo-electron microscopy

artículo científico publicado en 2018

PA tag: a versatile protein tagging system using a super high affinity antibody against a dodecapeptide derived from human podoplanin

artículo científico publicado en 2014

Potentiation of the ligand-binding activity of integrin alpha3beta1 via association with tetraspanin CD151

artículo científico publicado en 2005

Probing conformational and functional states of human hepatocyte growth factor by a panel of monoclonal antibodies

artículo científico publicado en 2016

Production, crystallization and preliminary crystallographic analysis of an exosite-containing fragment of human von Willebrand factor-cleaving proteinase ADAMTS13.

artículo científico publicado en 2009

Redox-assisted regulation of Ca2+ homeostasis in the endoplasmic reticulum by disulfide reductase ERdj5.

artículo científico publicado en 2016

Schwann cell myelination requires integration of laminin activities

artículo científico publicado en 2012

Semaphorin 6D reverse signaling controls macrophage lipid metabolism and anti-inflammatory polarization.

artículo científico publicado en 2018

Semaphorin 7A initiates T-cell-mediated inflammatory responses through alpha1beta1 integrin

scientific journal article

Site-specific epitope insertion into recombinant proteins using the MAP tag system

artículo científico publicado en 2020

Structural Basis for Variant-Specific Neuroligin-Binding by α-Neurexin

artículo científico publicado en 2011

Structural Basis of Sarco/Endoplasmic Reticulum Ca2+-ATPase 2b Regulation via Transmembrane Helix Interplay

artículo científico publicado en 2019

Structural basis for amyloidogenic peptide recognition by sorLA

artículo científico publicado en 2015

Structural basis for ligand capture and release by the endocytic receptor ApoER2.

artículo científico publicado en 2017

Structural basis for multi-specific peptide recognition by the anti-IDH1/2 monoclonal antibody, MsMab-1

artículo científico publicado en 2016

Structural basis for oligomerization of the prokaryotic peptide transporter PepT

artículo científico publicado en 2019

Structural basis for perception of diverse chemical substances by T1r taste receptors

artículo científico publicado en 2017

Structural basis for semaphorin signalling through the plexin receptor

artículo científico publicado en 2010

Structural basis for specific recognition of reelin by its receptors

artículo científico publicado en 2010

Structural mechanism of laminin recognition by integrin

artículo científico publicado en 2021

Structural studies of reelin N-terminal region provides insights into a unique structural arrangement and functional multimerization

artículo científico publicado en 2020

Structure and biological function of ENPP6, a choline-specific glycerophosphodiester-phosphodiesterase

artículo científico publicado en 2016

Structure and mechanism of cancer-associated N-acetylglucosaminyltransferase-V

artículo científico publicado en 2018

Structure of a receptor-binding fragment of reelin and mutational analysis reveal a recognition mechanism similar to endocytic receptors

artículo científico publicado en 2007

Structure of a signaling-competent reelin fragment revealed by X-ray crystallography and electron tomography

artículo científico publicado en 2006

Structure of the F-spondin reeler domain reveals a unique beta-sandwich fold with a deformable disulfide-bonded loop

artículo científico publicado en 2008

Structure of the Plexin Ectodomain Bound by Semaphorin-Mimicking Antibodies

artículo científico publicado en 2016

Tailored placement of a turn-forming PA tag into the structured domain of a protein to probe its conformational state

artículo científico publicado en 2016

The PA Tag: A Versatile Peptide Tagging System in the Era of Integrative Structural Biology

artículo científico publicado en 2018

The activated conformation of integrin β7 is a novel multiple myeloma-specific target for CAR T cell therapy

artículo científico publicado en 2017

The constitutive high affinity Met binding site in the kringle domain is dispensable for the signaling activity of hepatocyte growth factor

artículo científico publicado en 2020

Three-dimensional architecture of virus-packed tubule

artículo científico publicado en 2007

Tilt-angle measurement of a sample stage using a capacitive liquid-based inclinometer

artículo científico publicado en 2012

Yeast Inner-Subunit PA-NZ-1 Labeling Strategy for Accurate Subunit Identification in a Macromolecular Complex through Cryo-EM Analysis

artículo científico publicado en 2018

[Complex between nidogen and laminin fragments reveals a paradigmatic beta-propeller interface].

artículo científico publicado en 2003

[Multiple discontinuous exosites for von Willebrand factor of ADAMTS13]

artículo científico publicado en 2010

Lista de obras de

2D hybrid analysis: Approach for building three-dimensional atomic model by electron microscopy image matching.

A multipurpose fusion tag derived from an unstructured and hyperacidic region of the amyloid precursor protein ⬇️

A murine monoclonal antibody that binds N-terminal extracellular segment of human protease-activated receptor-4.

A point mutation in Semaphorin 4A associates with defective endosomal sorting and causes retinal degeneration.

A rapid screening method for cell lines producing singly-tagged recombinant proteins using the "TARGET tag" system

A structure-based model of substrate discrimination by a noncanonical PDZ tandem in the intramembrane-cleaving protease RseP

A systematic survey of conformational states in β1 and β4 integrins using negative-stain electron microscopy

Active and water-soluble form of lipidated Wnt protein is maintained by a serum glycoprotein afamin/α-albumin.

Advances in domain and subunit localization technology for electron microscopy

Allosteric Inhibition of a Semaphorin 4D Receptor Plexin B1 by a High-Affinity Macrocyclic Peptide

An anti-peptide monoclonal antibody recognizing the tobacco etch virus protease-cleavage sequence and its application to a tandem tagging system.

Cellular signaling and gene expression profiles evoked by a bivalent macrocyclic peptide that serves as an artificial MET receptor agonist

Clonal evolution and antigen recognition of anti-nuclear antibodies in acute systemic lupus erythematosus.

Conformational Freedom of the LRP6 Ectodomain Is Regulated by N-glycosylation and the Binding of the Wnt Antagonist Dkk1.

Corrigendum: Immune evasion of Plasmodium falciparum by RIFIN via inhibitory receptors

Crystal structure of Enpp1, an extracellular glycoprotein involved in bone mineralization and insulin signaling

Crystal structure of a mammalian Wnt-frizzled complex

Crystal structure of autotaxin and insight into GPCR activation by lipid mediators

Crystal structure of α5β1 integrin ectodomain: Atomic details of the fibronectin receptor ⬇️

Crystal structures of the noncatalytic domains of ADAMTS13 reveal multiple discontinuous exosites for von Willebrand factor

Crystallization and preliminary crystallographic analysis of human LR11 Vps10p domain.

De novo peptide grafting to a self-assembling nanocapsule yields a hepatocyte growth factor receptor agonist

Detection of endogenous LRP6 expressed on human cells by monoclonal antibodies specific for the native conformation.

Development of a new protein labeling system to map subunits and domains of macromolecular complexes for electron microscopy.

Development of a novel affinity tag system for the next generation structural biology

Development of cyclic peptides with potent in vivo osteogenic activity through RaPID-based affinity maturation

Distinct Localization of Mature HGF from its Precursor Form in Developing and Repairing the Stomach

Dynamic regulation of receptor transmembrane domain assembly during signal transmission across the plasma membrane

Engineered ACE2 receptor therapy overcomes mutational escape of SARS-CoV-2

Engineering ACE2 decoy receptors to combat viral escapability

Expression, purification, crystallization and preliminary X-ray crystallographic analysis of Enpp1.

Expression, purification, crystallization and preliminary X-ray crystallographic analysis of Enpp6.

Facile Synthesis of Dimeric Thioether-Macrocyclic Peptides with Antibody-like Affinity against Plexin-B1

First atomic view of alpha V beta 3 integrin extracellular domain

Functional importance of covalent homodimer of reelin protein linked via its central region

Functional role of the Frizzled linker domain in the Wnt signaling pathway

Fv-clasp: An Artificially Designed Small Antibody Fragment with Improved Production Compatibility, Stability, and Crystallizability

Higher-order architecture of cell adhesion mediated by polymorphic synaptic adhesion molecules neurexin and neuroligin

Immune evasion of Plasmodium falciparum by RIFIN via inhibitory receptors

Immunoaffinity Purification of the Glycosylated Extracellular Fragment of Mouse Plexin A2 Produced in a Mammalian Expression System

Impaired ligand-dependent MET activation caused by an extracellular SEMA domain missense mutation in lung cancer

Interplay of Endosomal pH and Ligand Occupancy in Integrin α5β1 Ubiquitination, Endocytic Sorting, and Cell Migration

Key interactions in integrin ectodomain responsible for global conformational change detected by elastic network normal-mode analysis

Ligand-binding specificities of laminin-binding integrins: a comprehensive survey of laminin-integrin interactions using recombinant alpha3beta1, alpha6beta1, alpha7beta1 and alpha6beta4 integrins

Loss of Parkinson's disease-associated protein CHCHD2 affects mitochondrial crista structure and destabilizes cytochrome c

Lysosomal sorting of amyloid-β by the SORLA receptor is impaired by a familial Alzheimer's disease mutation

Macrocyclic peptide-based inhibition and imaging of hepatocyte growth factor

Mechanistic basis for the recognition of laminin-511 by α6β1 integrin.

Mechanistic insights into ectodomain shedding: susceptibility of CADM1 adhesion molecule is determined by alternative splicing and O-glycosylation.

Molecular Basis of the Ligand Binding Specificity of αvβ8 Integrin

Molecular basis of the recognition of nephronectin by integrin alpha8beta1

Negatively charged amino acids in the stalk region of membrane proteins reduce ectodomain shedding

New era of structural analysis of proteins by electron microscopy-application to a dynamic structural analysis of integrin cell adhesion receptor-

Novel affinity tag system using structurally defined antibody-tag interaction: Application to single-step protein purification

Off-axis rotor in Enterococcus hirae V-ATPase visualized by Zernike phase plate single-particle cryo-electron microscopy

PA tag: a versatile protein tagging system using a super high affinity antibody against a dodecapeptide derived from human podoplanin

Potentiation of the ligand-binding activity of integrin alpha3beta1 via association with tetraspanin CD151

Probing conformational and functional states of human hepatocyte growth factor by a panel of monoclonal antibodies

Production, crystallization and preliminary crystallographic analysis of an exosite-containing fragment of human von Willebrand factor-cleaving proteinase ADAMTS13.

Redox-assisted regulation of Ca2+ homeostasis in the endoplasmic reticulum by disulfide reductase ERdj5.

Schwann cell myelination requires integration of laminin activities

Semaphorin 6D reverse signaling controls macrophage lipid metabolism and anti-inflammatory polarization.

Semaphorin 7A initiates T-cell-mediated inflammatory responses through alpha1beta1 integrin

Site-specific epitope insertion into recombinant proteins using the MAP tag system

Structural Basis for Variant-Specific Neuroligin-Binding by α-Neurexin

Structural Basis of Sarco/Endoplasmic Reticulum Ca2+-ATPase 2b Regulation via Transmembrane Helix Interplay

Structural basis for amyloidogenic peptide recognition by sorLA

Structural basis for ligand capture and release by the endocytic receptor ApoER2.

Structural basis for multi-specific peptide recognition by the anti-IDH1/2 monoclonal antibody, MsMab-1

Structural basis for oligomerization of the prokaryotic peptide transporter PepT

Structural basis for perception of diverse chemical substances by T1r taste receptors

Structural basis for semaphorin signalling through the plexin receptor

Structural basis for specific recognition of reelin by its receptors

Structural mechanism of laminin recognition by integrin

Structural studies of reelin N-terminal region provides insights into a unique structural arrangement and functional multimerization

Structure and biological function of ENPP6, a choline-specific glycerophosphodiester-phosphodiesterase

Structure and mechanism of cancer-associated N-acetylglucosaminyltransferase-V

Structure of a receptor-binding fragment of reelin and mutational analysis reveal a recognition mechanism similar to endocytic receptors

Structure of a signaling-competent reelin fragment revealed by X-ray crystallography and electron tomography