Lista de obras -

A Functional Immune System Is Required for the Systemic Genotoxic Effects of Localized Irradiation

scientific article published on 06 December 2018

A prototypical non-malignant epithelial model to study genome dynamics and concurrently monitor micro-RNAs and proteins in situ during oncogene-induced senescence

artículo científico publicado en 2018

A study concerning morphometry of abdominal aorta branches and abdominal viscera: relations and correlation

artículo científico

ARF: a versatile DNA damage response ally at the crossroads of development and tumorigenesis.

artículo científico publicado en 2014

Age-associated inflammation connects RAS-induced senescence to stem cell dysfunction and epidermal malignancy

artículo científico publicado en 2015

Ageing, Cellular Senescence and Neurodegenerative Disease

artículo científico publicado en 2018

Alterations in the Proliferating Compartment of Gastric Mucosa during Helicobacter Pylori Infection: The Putative Role of Epithelial Cells Expressing p27kip1 ⬇️

artículo científico publicado el 1 de noviembre de 2003

Annexin A3 is a mammary marker and a potential neoplastic breast cell therapeutic target

artículo científico publicado en 2015

Apidima Cave fossils provide earliest evidence of Homo sapiens in Eurasia

artículo científico publicado en 2019

Apoptosis or senescence? Which exit route do epithelial cells and fibroblasts preferentially follow?

artículo científico publicado en 2016

Apoptotic and proliferative status in HPV (+) and HPV (-) inverted papilloma patients. Correlation with local recurrence and clinicopathological variables

artículo científico publicado el 4 de mayo de 2012

Applying Broadband Dielectric Spectroscopy (BDS) for the Biophysical Characterization of Mammalian Tissues under a Variety of Cellular Stresses.

artículo científico publicado en 2017

Assessing drug development risk using Big Data and Machine Learning

artículo científico publicado en 2020

CRISPR-Cas9-mediated induction of large chromosomal inversions in human bronchial epithelial cells

artículo científico publicado en 2022

Chronic expression of p16INK4a in the epidermis induces Wnt-mediated hyperplasia and promotes tumor initiation

artículo científico publicado en 2020

Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing

artículo científico publicado en 2016

Combined Virtual and Experimental Screening for CK1 Inhibitors Identifies a Modulator of p53 and Reveals Important Aspects of in Silico Screening Performance

artículo científico publicado en 2017

Conditioning attenuates kidney and heart injury in rats following transient suprarenal occlusion of the abdominal aorta

scientific article published on 19 March 2020

Cura"x"ing Cancer and Beyond

artículo científico publicado en 2018

DNA Damage Response and Autophagy: A Meaningful Partnership

artículo científico publicado en 2016

DNA Damage Signaling Instructs Polyploid Macrophage Fate in Granulomas

artículo científico publicado en 2018

DNA Damage Signaling Instructs Polyploid Macrophage Fate in Granulomas.

artículo científico publicado en 2016

Deep learning: shaping the medicine of tomorrow

scientific article published on 19 February 2020

Defective DNA repair and chromatin organization in patients with quiescent systemic lupus erythematosus.

artículo científico publicado en 2016

Detection of Herplex Simplex Virus-1 and -2 in Cardiac Myxomas ⬇️

artículo científico publicado el 28 de febrero de 2012

Differential regulation of proteasome functionality in reproductive vs. somatic tissues of Drosophila during aging or oxidative stress ⬇️

artículo científico publicado el 1 de marzo de 2013

Dual function of p38α MAPK in colon cancer: suppression of colitis-associated tumor initiation but requirement for cancer cell survival

artículo científico publicado en 2014

Erratum to ‘Exploring and exploiting the systemic effects of deregulated replication licensing’ [Seminars in Cancer Biology 37–38C, (2016) 3–15]

artículo científico publicado en 2017

Ex vivo culture of cells derived from circulating tumour cell xenograft to support small cell lung cancer research and experimental therapeutics

scientific article published on 13 December 2018

Geminin ablation in vivo enhances tumorigenesis through increased genomic instability

artículo científico publicado en 2018

HPV-associated lung cancers: an international pooled analysis.

artículo científico publicado en 2014

HPV16 E6/E7 expression in circulating tumor cells in oropharyngeal squamous cell cancers: A pilot study

scientific article published on 09 May 2019

Hepatocyte autotaxin expression promotes liver fibrosis and cancer.

artículo científico publicado en 2016

Hyperactivation of Nrf2 increases stress tolerance at the cost of aging acceleration due to metabolic deregulation

artículo científico publicado en 2018

Immunohisto(cyto)chemistry: an old time classic tool driving modern oncological therapies

scientific article published on 27 November 2018

In situ evidence of cellular senescence in Thymic Epithelial Cells (TECs) during human thymic involution.

artículo científico publicado en 2018

Inflammation, DNA Damage, Helicobacter pylori and Gastric Tumorigenesis

scientific article published on 27 February 2017

Integrating the DNA damage and protein stress responses during cancer development and treatment.

artículo científico publicado en 2018

Ionizing radiation-mediated premature senescence and paracrine interactions with cancer cells enhance the expression of syndecan 1 in human breast stromal fibroblasts: the role of TGF-β.

artículo científico publicado en 2016

Karyotypic Flexibility of the Complex Cancer Genome and the Role of Polyploidization in Maintenance of Structural Integrity of Cancer Chromosomes

artículo científico publicado en 2020

LATS1 and LATS2 suppress breast cancer progression by maintaining cell identity and metabolic state

scientific article published on 30 October 2018

Localized Synchrotron Irradiation of Mouse Skin Induces Persistent Systemic Genotoxic and Immune Responses

artículo científico publicado en 2017

MST2 kinase suppresses rDNA transcription in response to DNA damage by phosphorylating nucleolar histone H2B.

artículo científico publicado en 2018

MiR-signing gastrointestinal (con-)tract cancer

artículo científico publicado en 2017

Mitochondrial Homeostasis and Cellular Senescence

scientific article published on 06 July 2019

Monitoring Autophagy Immunohistochemically and Ultrastructurally during Human Head and Neck Carcinogenesis. Relationship with the DNA Damage Response Pathway.

artículo científico publicado en 2017

Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246.

artículo científico publicado en 2018

Mutant p53 gain of function underlies high expression levels of colorectal cancer stem cells markers.

artículo científico publicado en 2018

Mutational signatures reveal the role of RAD52 in p53-independent p21-driven genomic instability.

artículo científico publicado en 2018

N-bromotaurine surrogates for loss of antiproliferative response and enhances cisplatin efficacy in cancer cells with impaired glucocorticoid receptor.

artículo científico publicado en 2016

Non-enzymatic post-translational protein modifications and proteostasis network deregulation in carcinogenesis ⬇️

artículo científico publicado el 14 de marzo de 2013

Oncogene-induced reactive oxygen species fuel hyperproliferation and DNA damage response activation

artículo científico publicado en 2014

Oncogene-induced senescence: the bright and dark side of the response ⬇️

artículo científico publicado el 16 de septiembre de 2010

Oncogenic Role of the Ec Peptide of the IGF-1Ec Isoform in Prostate Cancer

artículo científico publicado en 2015

PIG3: A novel link between oxidative stress and DNA damage response in cancer ⬇️

artículo científico publicado el 14 de diciembre de 2011

Progression of mouse skin carcinogenesis is associated with the orchestrated deregulation of mir-200 family members, mir-205 and their common targets

artículo científico

Proteasome dysfunction induces excessive proteome instability and loss of mitostasis that can be mitigated by enhancing mitochondrial fusion or autophagy

artículo científico publicado en 2019

Proteome Stability as a Key Factor of Genome Integrity

artículo científico publicado en 2017

RNF20 Links Histone H2B Ubiquitylation with Inflammation and Inflammation-Associated Cancer

artículo científico publicado en 2016

RNF20 and histone H2B ubiquitylation exert opposing effects in Basal-Like versus luminal breast cancer

artículo científico publicado en 2017

SCF(Cyclin F)-dependent degradation of CDC6 suppresses DNA re-replication

artículo científico publicado en 2016

Senescence and senotherapeutics: a new field in cancer therapy

artículo científico publicado en 2018

Specific lipofuscin staining as a novel biomarker to detect replicative and stress-induced senescence. A method applicable in cryo-preserved and archival tissues ⬇️

artículo científico publicado el 1 de enero de 2013

Sudan Black B, The Specific Histochemical Stain for Lipofuscin: A Novel Method to Detect Senescent Cells.

artículo científico

Systemic dna damage: Mechanisms, effects and mitigation strategies.

artículo científico publicado en 2016

The Janus face of p21.

artículo científico publicado en 2016

The Tumor Suppressor Gene ARF as a Sensor of Oxidative Stress ⬇️

artículo científico publicado el 1 de julio de 2012

The Typhoid Toxin Promotes Host Survival and the Establishment of a Persistent Asymptomatic Infection

artículo científico publicado en 2016

The oncogenic JUNB/CD30 axis contributes to cell cycle deregulation in ALK+ anaplastic large cell lymphoma.

artículo científico publicado en 2014

The role of oxidative DNA damage in radiation induced bystander effect

artículo científico

Tissue-infiltrating macrophages mediate an exosome-based metabolic reprogramming upon DNA damage

scientific article published on 02 January 2020

Unique Spatial Immune Profiling in Pancreatic Ductal Adenocarcinoma with Enrichment of Exhausted and Senescent T Cells and Diffused CD47-SIRPα Expression

artículo científico publicado en 2020

Unravelling a p73-regulated network: The role of a novel p73-dependent target, MIR3158, in cancer cell migration and invasiveness.

artículo científico publicado en 2016

Unreplicated DNA remaining from unperturbed S phases passes through mitosis for resolution in daughter cells

artículo científico publicado en 2016

Upregulation and nuclear localization of TNF‐like Cytokine 1A (TL1A) and its receptors DR3 and DcR3 in psoriatic skin lesions ⬇️

artículo científico publicado el 14 de junio de 2011

Upregulation of Human Endogenous Retroviruses in Bronchoalveolar Lavage Fluid of COVID-19 Patients

artículo científico publicado en 2020

Validation and development of MTH1 inhibitors for treatment of cancer.

artículo científico publicado en 2016

Versican modulates tumor-associated macrophage properties to stimulate mesothelioma growth

scientific article published on 02 November 2018

p21WAF1/Cip1 - PCNA: Fatal attraction

artículo científico publicado en 2016

Lista de obras de

A Functional Immune System Is Required for the Systemic Genotoxic Effects of Localized Irradiation

A prototypical non-malignant epithelial model to study genome dynamics and concurrently monitor micro-RNAs and proteins in situ during oncogene-induced senescence

A study concerning morphometry of abdominal aorta branches and abdominal viscera: relations and correlation

ARF: a versatile DNA damage response ally at the crossroads of development and tumorigenesis.

Age-associated inflammation connects RAS-induced senescence to stem cell dysfunction and epidermal malignancy

Ageing, Cellular Senescence and Neurodegenerative Disease

Alterations in the Proliferating Compartment of Gastric Mucosa during Helicobacter Pylori Infection: The Putative Role of Epithelial Cells Expressing p27kip1 ⬇️

Annexin A3 is a mammary marker and a potential neoplastic breast cell therapeutic target

Apidima Cave fossils provide earliest evidence of Homo sapiens in Eurasia

Apoptosis or senescence? Which exit route do epithelial cells and fibroblasts preferentially follow?

Apoptotic and proliferative status in HPV (+) and HPV (-) inverted papilloma patients. Correlation with local recurrence and clinicopathological variables

Applying Broadband Dielectric Spectroscopy (BDS) for the Biophysical Characterization of Mammalian Tissues under a Variety of Cellular Stresses.

Assessing drug development risk using Big Data and Machine Learning

CRISPR-Cas9-mediated induction of large chromosomal inversions in human bronchial epithelial cells

Chronic expression of p16INK4a in the epidermis induces Wnt-mediated hyperplasia and promotes tumor initiation

Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing

Combined Virtual and Experimental Screening for CK1 Inhibitors Identifies a Modulator of p53 and Reveals Important Aspects of in Silico Screening Performance

Conditioning attenuates kidney and heart injury in rats following transient suprarenal occlusion of the abdominal aorta

Cura"x"ing Cancer and Beyond

DNA Damage Response and Autophagy: A Meaningful Partnership

DNA Damage Signaling Instructs Polyploid Macrophage Fate in Granulomas

DNA Damage Signaling Instructs Polyploid Macrophage Fate in Granulomas.

Deep learning: shaping the medicine of tomorrow

Defective DNA repair and chromatin organization in patients with quiescent systemic lupus erythematosus.

Detection of Herplex Simplex Virus-1 and -2 in Cardiac Myxomas ⬇️

Differential regulation of proteasome functionality in reproductive vs. somatic tissues of Drosophila during aging or oxidative stress ⬇️

Dual function of p38α MAPK in colon cancer: suppression of colitis-associated tumor initiation but requirement for cancer cell survival

Erratum to ‘Exploring and exploiting the systemic effects of deregulated replication licensing’ [Seminars in Cancer Biology 37–38C, (2016) 3–15]

Ex vivo culture of cells derived from circulating tumour cell xenograft to support small cell lung cancer research and experimental therapeutics

Geminin ablation in vivo enhances tumorigenesis through increased genomic instability

HPV-associated lung cancers: an international pooled analysis.

HPV16 E6/E7 expression in circulating tumor cells in oropharyngeal squamous cell cancers: A pilot study

Hepatocyte autotaxin expression promotes liver fibrosis and cancer.

Hyperactivation of Nrf2 increases stress tolerance at the cost of aging acceleration due to metabolic deregulation

Immunohisto(cyto)chemistry: an old time classic tool driving modern oncological therapies

In situ evidence of cellular senescence in Thymic Epithelial Cells (TECs) during human thymic involution.

Inflammation, DNA Damage, Helicobacter pylori and Gastric Tumorigenesis

Integrating the DNA damage and protein stress responses during cancer development and treatment.

Ionizing radiation-mediated premature senescence and paracrine interactions with cancer cells enhance the expression of syndecan 1 in human breast stromal fibroblasts: the role of TGF-β.

Karyotypic Flexibility of the Complex Cancer Genome and the Role of Polyploidization in Maintenance of Structural Integrity of Cancer Chromosomes

LATS1 and LATS2 suppress breast cancer progression by maintaining cell identity and metabolic state

Localized Synchrotron Irradiation of Mouse Skin Induces Persistent Systemic Genotoxic and Immune Responses

MST2 kinase suppresses rDNA transcription in response to DNA damage by phosphorylating nucleolar histone H2B.

MiR-signing gastrointestinal (con-)tract cancer

Mitochondrial Homeostasis and Cellular Senescence

Monitoring Autophagy Immunohistochemically and Ultrastructurally during Human Head and Neck Carcinogenesis. Relationship with the DNA Damage Response Pathway.

Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246.

Mutant p53 gain of function underlies high expression levels of colorectal cancer stem cells markers.

Mutational signatures reveal the role of RAD52 in p53-independent p21-driven genomic instability.

N-bromotaurine surrogates for loss of antiproliferative response and enhances cisplatin efficacy in cancer cells with impaired glucocorticoid receptor.

Non-enzymatic post-translational protein modifications and proteostasis network deregulation in carcinogenesis ⬇️

Oncogene-induced reactive oxygen species fuel hyperproliferation and DNA damage response activation

Oncogene-induced senescence: the bright and dark side of the response ⬇️

Oncogenic Role of the Ec Peptide of the IGF-1Ec Isoform in Prostate Cancer

PIG3: A novel link between oxidative stress and DNA damage response in cancer ⬇️

Progression of mouse skin carcinogenesis is associated with the orchestrated deregulation of mir-200 family members, mir-205 and their common targets

Proteasome dysfunction induces excessive proteome instability and loss of mitostasis that can be mitigated by enhancing mitochondrial fusion or autophagy

Proteome Stability as a Key Factor of Genome Integrity

RNF20 Links Histone H2B Ubiquitylation with Inflammation and Inflammation-Associated Cancer

RNF20 and histone H2B ubiquitylation exert opposing effects in Basal-Like versus luminal breast cancer

SCF(Cyclin F)-dependent degradation of CDC6 suppresses DNA re-replication

Senescence and senotherapeutics: a new field in cancer therapy

Specific lipofuscin staining as a novel biomarker to detect replicative and stress-induced senescence. A method applicable in cryo-preserved and archival tissues ⬇️

Sudan Black B, The Specific Histochemical Stain for Lipofuscin: A Novel Method to Detect Senescent Cells.

Systemic dna damage: Mechanisms, effects and mitigation strategies.

The Janus face of p21.

The Tumor Suppressor Gene ARF as a Sensor of Oxidative Stress ⬇️

The Typhoid Toxin Promotes Host Survival and the Establishment of a Persistent Asymptomatic Infection

The oncogenic JUNB/CD30 axis contributes to cell cycle deregulation in ALK+ anaplastic large cell lymphoma.

The role of oxidative DNA damage in radiation induced bystander effect

Tissue-infiltrating macrophages mediate an exosome-based metabolic reprogramming upon DNA damage

Unique Spatial Immune Profiling in Pancreatic Ductal Adenocarcinoma with Enrichment of Exhausted and Senescent T Cells and Diffused CD47-SIRPα Expression

Unravelling a p73-regulated network: The role of a novel p73-dependent target, MIR3158, in cancer cell migration and invasiveness.

Unreplicated DNA remaining from unperturbed S phases passes through mitosis for resolution in daughter cells

Upregulation and nuclear localization of TNF‐like Cytokine 1A (TL1A) and its receptors DR3 and DcR3 in psoriatic skin lesions ⬇️

Upregulation of Human Endogenous Retroviruses in Bronchoalveolar Lavage Fluid of COVID-19 Patients

Validation and development of MTH1 inhibitors for treatment of cancer.

Versican modulates tumor-associated macrophage properties to stimulate mesothelioma growth

p21WAF1/Cip1 - PCNA: Fatal attraction