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APOE Isoforms Control Pathogenic Subretinal Inflammation in Age-Related Macular Degeneration

artículo científico publicado en 2015

Apolipoprotein E promotes subretinal mononuclear phagocyte survival and chronic inflammation in age-related macular degeneration

artículo científico publicado en 2015

CCR2(+) monocytes infiltrate atrophic lesions in age-related macular disease and mediate photoreceptor degeneration in experimental subretinal inflammation in Cx3cr1 deficient mice

artículo científico publicado en 2013

CD36 deficiency leads to choroidal involution via COX2 down-regulation in rodents

scientific article (publication date: February 2008)

CX3CR1-dependent subretinal microglia cell accumulation is associated with cardinal features of age-related macular degeneration.

artículo científico publicado en 2007

Complement Factor H Inhibits CD47-Mediated Resolution of Inflammation.

artículo científico publicado en 2017

Erratum to: Delta-like 4 inhibits choroidal neovascularization despite opposing effects on vascular endothelium and macrophages.

artículo científico publicado en 2012

Interleukin-1β inhibition prevents choroidal neovascularization and does not exacerbate photoreceptor degeneration.

artículo científico publicado en 2011

MFGE8 does not influence chorio-retinal homeostasis or choroidal neovascularization in vivo.

artículo científico publicado en 2012

Neonatal hyperglycemia inhibits angiogenesis and induces inflammation and neuronal degeneration in the retina

artículo científico publicado en 2013

Netrin-4 inhibits angiogenesis via binding to neogenin and recruitment of Unc5B.

artículo científico publicado en 2008

Subretinal mononuclear phagocytes induce cone segment loss via IL-1β.

artículo científico publicado en 2016

Thinning of the RPE and choroid associated with T lymphocyte recruitment in aged and light-challenged mice.

artículo científico publicado en 2015

Upregulation of P2RX7 in Cx3cr1-Deficient Mononuclear Phagocytes Leads to Increased Interleukin-1β Secretion and Photoreceptor Neurodegeneration.

artículo científico publicado en 2015

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