Lista de obras -

14-3-3 proteins recognize a histone code at histone H3 and are required for transcriptional activation

artículo científico publicado en 2007

A cascade of histone modifications induces chromatin condensation in mitosis.

artículo científico publicado en 2014

A chromatin-dependent role of the fragile X mental retardation protein FMRP in the DNA damage response

scientific journal article

A dual role of H4K16 acetylation in the establishment of yeast silent chromatin.

artículo científico publicado en 2011

A multilaboratory comparison of calibration accuracy and the performance of external references in analytical ultracentrifugation

artículo científico publicado en 2015

A stable transcription factor complex nucleated by oligomeric AML1–ETO controls leukaemogenesis ⬇️

artículo científico publicado el 30 de junio de 2013

Accessibility of different histone H3-binding domains of UHRF1 is allosterically regulated by phosphatidylinositol 5-phosphate

artículo científico publicado en 2014

Assays for the determination of structure and dynamics of the interaction of the chromodomain with histone peptides

artículo científico publicado en 2004

Beyond the double helix: writing and reading the histone code.

artículo científico publicado en 2004

Chemistry meets epigenetics: from chromatin tools to small molecules affecting the readout of our genomes

artículo científico publicado en 2018

Chromatin affinity purification and quantitative mass spectrometry defining the interactome of histone modification patterns.

artículo científico publicado en 2011

Chromatin regulated interchange between polycomb repressive complex 2 (PRC2)-Ezh2 and PRC2-Ezh1 complexes controls myogenin activation in skeletal muscle cells

artículo científico publicado en 2011

Conserved linker regions and their regulation determine multiple chromatin-binding modes of UHRF1

artículo científico publicado en 2015

Control of cytomegalovirus lytic gene expression by histone acetylation

artículo científico publicado en 2002

Dynamic and flexible H3K9me3 bridging via HP1β dimerization establishes a plastic state of condensed chromatin.

artículo científico publicado en 2016

Enzymatic activity associated with class II HDACs is dependent on a multiprotein complex containing HDAC3 and SMRT/N-CoR

artículo científico publicado en 2002

Epigenetic markers and their cross-talk ⬇️

artículo científico publicado el 20 de septiembre de 2010

H3K9me2/3 Binding of the MBT Domain Protein LIN-61 Is Essential for Caenorhabditis elegans Vulva Development ⬇️

artículo científico publicado el 17 de marzo de 2011

HDAC7, a thymus-specific class II histone deacetylase, regulates Nur77 transcription and TCR-mediated apoptosis

artículo científico publicado en 2003

HIS-24 linker histone and SIR-2.1 deacetylase induce H3K27me3 in the Caenorhabditis elegans germ line

artículo científico publicado en 2009

HP1 recruits activity-dependent neuroprotective protein to H3K9me3 marked pericentromeric heterochromatin for silencing of major satellite repeats

artículo científico publicado en 2011

Heterochromatin protein 1 forms distinct complexes to direct histone deacetylation and DNA methylation

artículo científico publicado en 2012

Histone methylation by PRC2 is inhibited by active chromatin marks

artículo científico publicado en 2011

In nucleo enzymatic assays for the identification and characterization of histone modifying activities

artículo científico publicado en 2005

Measurement of mammalian histone deacetylase activity

artículo científico publicado en 2004

Mitochondrial SIRT4-type proteins in Caenorhabditis elegans and mammals interact with pyruvate carboxylase and other acetylated biotin-dependent carboxylases

artículo científico publicado en 2013

Modulation of 14-3-3 interaction with phosphorylated histone H3 by combinatorial modification patterns

artículo científico publicado en 2008

Modulations of DNA Contacts by Linker Histones and Post-translational Modifications Determine the Mobility and Modifiability of Nucleosomal H3 Tails

artículo científico publicado en 2016

Molecular architecture of the human Prp19/CDC5L complex

artículo científico publicado en 2010

Molecular basis for the discrimination of repressive methyl-lysine marks in histone H3 by Polycomb and HP1 chromodomains

artículo científico publicado en 2003

Multimerization and H3K9me3 binding are required for CDYL1b heterochromatin association

artículo científico publicado en 2009

N-terminal phosphorylation of HP1α increases its nucleosome-binding specificity

artículo científico publicado en 2014

Nuclear localization and phosphorylation modulate pathological effects of Alpha-Synuclein

artículo científico publicado en 2019

One, Two, Three: How Histone Methylation is Read ⬇️

artículo científico publicado el 1 de diciembre de 2012

Oxidative stress signaling to chromatin in health and disease.

artículo científico publicado en 2016

Phosphorylation of histone H3 Ser10 establishes a hierarchy for subsequent intramolecular modification events

artículo científico publicado en 2012

Polycomb-dependent H3K27me1 and H3K27me2 regulate active transcription and enhancer fidelity

artículo científico publicado en 2013

Probing Chromatin-modifying Enzymes with Chemical Tools.

artículo científico publicado en 2016

Quantitative assessment of protein interaction with methyl-lysine analogues by hybrid computational and experimental approaches

artículo científico publicado en 2011

RNAs - physical and functional modulators of chromatin reader proteins

artículo científico

Role of histone modifications in defining chromatin structure and function

artículo científico publicado en 2008

Specificity of the chromodomain Y chromosome family of chromodomains for lysine-methylated ARK(S/T) motifs

artículo científico publicado en 2008

Structural Basis for Lower Lysine Methylation State-Specific Readout by MBT Repeats of L3MBTL1 and an Engineered PHD Finger

artículo científico publicado en 2007

Structural and functional analyses of methyl-lysine binding by the malignant brain tumour repeat protein Sex comb on midleg

artículo científico publicado en 2007

Structural plasticity in human heterochromatin protein 1β

artículo científico publicado en 2013

Synthetic histone code.

artículo científico

Systematic analysis of histone modification readout ⬇️

artículo científico publicado el 4 de diciembre de 2012

TRIM24 links a non-canonical histone signature to breast cancer

artículo científico publicado en 2010

The basal transcription complex component TAF3 transduces changes in nuclear phosphoinositides into transcriptional output

artículo científico publicado en 2015

The emerging role of class II histone deacetylases

artículo científico publicado en 2001

Lista de obras de

14-3-3 proteins recognize a histone code at histone H3 and are required for transcriptional activation

A cascade of histone modifications induces chromatin condensation in mitosis.

A chromatin-dependent role of the fragile X mental retardation protein FMRP in the DNA damage response

A dual role of H4K16 acetylation in the establishment of yeast silent chromatin.

A multilaboratory comparison of calibration accuracy and the performance of external references in analytical ultracentrifugation

A stable transcription factor complex nucleated by oligomeric AML1–ETO controls leukaemogenesis ⬇️

Accessibility of different histone H3-binding domains of UHRF1 is allosterically regulated by phosphatidylinositol 5-phosphate

Assays for the determination of structure and dynamics of the interaction of the chromodomain with histone peptides

Beyond the double helix: writing and reading the histone code.

Chemistry meets epigenetics: from chromatin tools to small molecules affecting the readout of our genomes

Chromatin affinity purification and quantitative mass spectrometry defining the interactome of histone modification patterns.

Chromatin regulated interchange between polycomb repressive complex 2 (PRC2)-Ezh2 and PRC2-Ezh1 complexes controls myogenin activation in skeletal muscle cells

Conserved linker regions and their regulation determine multiple chromatin-binding modes of UHRF1

Control of cytomegalovirus lytic gene expression by histone acetylation

Dynamic and flexible H3K9me3 bridging via HP1β dimerization establishes a plastic state of condensed chromatin.

Enzymatic activity associated with class II HDACs is dependent on a multiprotein complex containing HDAC3 and SMRT/N-CoR

Epigenetic markers and their cross-talk ⬇️

H3K9me2/3 Binding of the MBT Domain Protein LIN-61 Is Essential for Caenorhabditis elegans Vulva Development ⬇️

HDAC7, a thymus-specific class II histone deacetylase, regulates Nur77 transcription and TCR-mediated apoptosis

HIS-24 linker histone and SIR-2.1 deacetylase induce H3K27me3 in the Caenorhabditis elegans germ line

HP1 recruits activity-dependent neuroprotective protein to H3K9me3 marked pericentromeric heterochromatin for silencing of major satellite repeats

Heterochromatin protein 1 forms distinct complexes to direct histone deacetylation and DNA methylation

Histone methylation by PRC2 is inhibited by active chromatin marks

In nucleo enzymatic assays for the identification and characterization of histone modifying activities

Measurement of mammalian histone deacetylase activity

Mitochondrial SIRT4-type proteins in Caenorhabditis elegans and mammals interact with pyruvate carboxylase and other acetylated biotin-dependent carboxylases

Modulation of 14-3-3 interaction with phosphorylated histone H3 by combinatorial modification patterns

Modulations of DNA Contacts by Linker Histones and Post-translational Modifications Determine the Mobility and Modifiability of Nucleosomal H3 Tails

Molecular architecture of the human Prp19/CDC5L complex

Molecular basis for the discrimination of repressive methyl-lysine marks in histone H3 by Polycomb and HP1 chromodomains

Multimerization and H3K9me3 binding are required for CDYL1b heterochromatin association

N-terminal phosphorylation of HP1α increases its nucleosome-binding specificity

Nuclear localization and phosphorylation modulate pathological effects of Alpha-Synuclein

One, Two, Three: How Histone Methylation is Read ⬇️

Oxidative stress signaling to chromatin in health and disease.

Phosphorylation of histone H3 Ser10 establishes a hierarchy for subsequent intramolecular modification events

Polycomb-dependent H3K27me1 and H3K27me2 regulate active transcription and enhancer fidelity

Probing Chromatin-modifying Enzymes with Chemical Tools.

Quantitative assessment of protein interaction with methyl-lysine analogues by hybrid computational and experimental approaches

RNAs - physical and functional modulators of chromatin reader proteins

Role of histone modifications in defining chromatin structure and function

Specificity of the chromodomain Y chromosome family of chromodomains for lysine-methylated ARK(S/T) motifs

Structural Basis for Lower Lysine Methylation State-Specific Readout by MBT Repeats of L3MBTL1 and an Engineered PHD Finger

Structural and functional analyses of methyl-lysine binding by the malignant brain tumour repeat protein Sex comb on midleg

Structural plasticity in human heterochromatin protein 1β

Synthetic histone code.

Systematic analysis of histone modification readout ⬇️

TRIM24 links a non-canonical histone signature to breast cancer

The basal transcription complex component TAF3 transduces changes in nuclear phosphoinositides into transcriptional output

The emerging role of class II histone deacetylases