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(13)C MRS and LC-MS Flux Analysis of Tumor Intermediary Metabolism

artículo científico publicado en 2016

A Systematic Review of Factors That Contribute to Hepatosplenic T-Cell Lymphoma in Patients With Inflammatory Bowel Disease

artículo científico publicado el 1 de octubre de 2010

A novel xenograft model of cutaneous T-cell lymphoma

artículo científico publicado en 2010

ACLY is the novel signaling target of PIP2/PIP3 and Lyn in acute myeloid leukemia

scientific article published on 07 May 2020

ALK inhibitor PF02341066 (crizotinib) increases sensitivity to radiation in non-small cell lung cancer expressing EML4-ALK.

artículo científico publicado en 2013

Activation of mTORC1 signaling pathway in AIDS-related lymphomas

artículo científico publicado en 2009

Activation of mammalian target of rapamycin in transformed B lymphocytes is nutrient dependent but independent of Akt, mitogen-activated protein kinase/extracellular signal-regulated kinase kinase, insulin growth factor-I, and serum.

artículo científico publicado en 2005

Anaplastic large cell lymphoma arises in thymocytes and requires transient TCR expression for thymic egress

artículo científico publicado en 2016

Anaplastic lymphoma kinase (ALK)-induced malignancies: novel mechanisms of cell transformation and potential therapeutic approaches

artículo científico publicado en 2009

Anaplastic lymphoma kinase is required for neurogenesis in the developing central nervous system of zebrafish

artículo científico publicado en 2013

Antibiotics inhibit tumor and disease activity in cutaneous T-cell lymphoma

scientific article published on 22 July 2019

Bacterial toxins fuel disease progression in cutaneous T-cell lymphoma

artículo científico publicado en 2013

Central photopenic lesions on FDG-PET scan in a patient with peripheral T cell lymphoma

artículo científico publicado en 2008

Chimeric Antigen Receptor T Cells in Refractory B-Cell Lymphomas

artículo científico publicado en 2017

Combined B12 and folate deficiency presenting as an aggressive hematologic malignancy.

artículo científico publicado en 2015

Complementary functions of the antiapoptotic protein A1 and serine/threonine kinase pim-1 in the BCR/ABL-mediated leukemogenesis

artículo científico publicado en 2002

Complete remission in advanced blastic NK-cell lymphoma/leukemia in elderly patients using the hyper-CVAD regimen

artículo científico publicado en 2003

Constitutive activation of mTOR signaling pathway in post-transplant lymphoproliferative disorders.

artículo científico publicado en 2006

Cutaneous T cell lymphoma expresses immunosuppressive CD80 (B7-1) cell surface protein in a STAT5-dependent manner

artículo científico publicado en 2014

Cutting Edge: ROR1/CD19 Receptor Complex Promotes Growth of Mantle Cell Lymphoma Cells Independently of the B Cell Receptor-BTK Signaling Pathway

scientific article published on 18 September 2019

Cytokine release syndrome associated with chimeric-antigen receptor T-cell therapy: clinicopathological insights

artículo científico publicado en 2017

Decreased lactate concentration and glycolytic enzyme expression reflect inhibition of mTOR signal transduction pathway in B-cell lymphoma

artículo científico publicado en 2012

Deficient SOCS3 and SHP-1 expression in psoriatic T cells

artículo científico publicado en 2010

Detection of Epstein-Barr virus in T-cell prolymphocytic leukemia cells in vitro

artículo científico publicado en 2008

Detection of protein tyrosine-kinase (PTK) gene expression pattern in normal and malignant T lymphocytes by combined PTK-specific polymerase chain reaction and parallel denaturing gradient gel electrophoresis

artículo científico publicado en 2003

Development of lymphomas containing Epstein-Barr virus after therapy with hyper-CVAD regimen

artículo científico publicado en 2013

Diagnostic microRNA profiling in cutaneous T-cell lymphoma (CTCL)

artículo científico publicado en 2011

Differential effects of interleukin-2 and interleukin-15 versus interleukin-21 on CD4+ cutaneous T-cell lymphoma cells

artículo científico publicado en 2008

Diminished expression of the type II receptor for TGFbeta (TGFbetaRII) in T lymphocytes from patients with Sezary syndrome is not due to mutations in the receptor's poly-A tract: limitations of the standard RT-PCR in cDNA sequence analysis of homopo

artículo científico publicado en 2002

Distinct miRNA profile in prognosis of early CTCL.

artículo científico publicado en 2018

Dramatic increase in gene mutational burden after transformation of follicular lymphoma into TdT+ B-lymphoblastic leukemia/lymphoma

artículo científico publicado en 2020

Dramatic response of acute monoblastic leukemia to a single dose of docetaxel

artículo científico publicado en 2008

Dynamic Changes in Gene Mutational Landscape With Preservation of Core Mutations in Mantle Cell Lymphoma Cells

artículo científico publicado en 2019

Ectopic expression of B-lymphoid kinase in cutaneous T-cell lymphoma

artículo científico publicado en 2009

Ectopic expression of a novel CD22 splice-variant regulates survival and proliferation in malignant T cells from cutaneous T cell lymphoma (CTCL) patients.

artículo científico publicado en 2015

Elucidating the role of interleukin-17F in cutaneous T-cell lymphoma

artículo científico publicado en 2013

Epstein-Barr Virus nuclear antigen 1 (EBNA1) confers resistance to apoptosis in EBV-positive B-lymphoma cells through up-regulation of survivin

artículo científico publicado en 2010

Expression and oncogenic role of Brk (PTK6/Sik) protein tyrosine kinase in lymphocytes.

artículo científico publicado en 2006

Expression of SHP-1 phosphatase indicates post-germinal center cell derivation of B-cell posttransplant lymphoproliferative disorders.

artículo científico publicado en 2002

Expression of T-plastin, FoxP3 and other tumor-associated markers by leukemic T-cells of cutaneous T-cell lymphoma.

artículo científico publicado en 2008

Expression of anaplastic lymphoma kinase in non-Hodgkin's lymphomas and other malignant neoplasms. Biological, diagnostic, and clinical implications

artículo científico publicado en 2002

Expression patterns of the immunosuppressive proteins PD-1/CD279 and PD-L1/CD274 at different stages of cutaneous T-cell lymphoma/mycosis fungoides

artículo científico publicado en 2012

From Pathology to Precision Medicine in Anaplastic Large Cell Lymphoma Expressing Anaplastic Lymphoma Kinase (ALK+ ALCL).

artículo científico publicado en 2017

Gamma c-signaling cytokines induce a regulatory T cell phenotype in malignant CD4+ T lymphocytes.

artículo científico publicado en 2008

Hepatosplenic T-Cell Lymphoma in Inflammatory Bowel Disease: A Possible Thiopurine-Induced Chromosomal Abnormality

artículo científico publicado el 1 de octubre de 2010

IFN-α primes T- and NK-cells for IL-15-mediated signaling and cytotoxicity.

artículo científico publicado en 2011

IGH/MYC Translocation Associates with BRCA2 Deficiency and Synthetic Lethality to PARP1 Inhibitors

artículo científico publicado en 2017

IL-13 as a novel growth factor in CTCL.

artículo científico publicado en 2015

IL-15 and IL-17F are differentially regulated and expressed in mycosis fungoides (MF).

artículo científico publicado en 2014

IL-2- and IL-15-induced activation of the rapamycin-sensitive mTORC1 pathway in malignant CD4+ T lymphocytes.

artículo científico publicado en 2007

IL-21 Enhances Antitumor Responses without Stimulating Proliferation of Malignant T Cells of Patients with Sézary Syndrome

article

IL-2R common γ-chain is epigenetically silenced by nucleophosphin–anaplastic lymphoma kinase (NPM-ALK) and acts as a tumor suppressor by targeting NPM-ALK

artículo científico publicado el 29 de junio de 2011

Id1 transcription inhibitor-matrix metalloproteinase 9 axis enhances invasiveness of the breakpoint cluster region/abelson tyrosine kinase-transformed leukemia cells.

artículo científico publicado en 2006

Immune modulators as therapeutic agents for cutaneous T-cell lymphoma

artículo científico publicado en 2010

Immunosuppressive TOR kinase inhibitor everolimus (RAD) suppresses growth of cells derived from posttransplant lymphoproliferative disorder at allograft-protecting doses

artículo científico publicado en 2003

Inhibition of ALK enzymatic activity in T-cell lymphoma cells induces apoptosis and suppresses proliferation and STAT3 phosphorylation independently of Jak3.

artículo científico publicado en 2005

Intravascular large B cell lymphoma presenting as a thyroid mass

artículo científico publicado en 2014

Jak3, STAT3, and STAT5 inhibit expression of miR-22, a novel tumor suppressor microRNA, in cutaneous T-Cell lymphoma

artículo científico publicado en 2015

LRPAP1 is a frequent proliferation-inducing antigen of BCRs of mantle cell lymphomas and can be used for specific therapeutic targeting

artículo científico publicado en 2018

Lack of TNFalpha expression protects anaplastic lymphoma kinase-positive T-cell lymphoma (ALK+ TCL) cells from apoptosis

artículo científico publicado en 2009

Loss of SHP-1 tyrosine phosphatase expression correlates with the advanced stages of cutaneous T-cell lymphoma

artículo científico publicado en 2007

Malignant T cells express lymphotoxin α and drive endothelial activation in cutaneous T cell lymphoma

artículo científico publicado en 2015

Malignant cutaneous T-cell lymphoma cells express IL-17 utilizing the Jak3/Stat3 signaling pathway

artículo científico publicado en 2011

Malignant inflammation in cutaneous T-cell lymphoma-a hostile takeover

artículo científico publicado en 2016

Malignant transformation of CD4+ T lymphocytes mediated by oncogenic kinase NPM/ALK recapitulates IL-2-induced cell signaling and gene expression reprogramming

artículo científico publicado en 2013

Mantle cell lymphoma cells express predominantly cyclin D1a isoform and are highly sensitive to selective inhibition of CDK4 kinase activity.

artículo científico publicado en 2006

Marginal zone lymphoma-derived interfollicular diffuse large B-cell lymphoma harboring 20q12 chromosomal deletion and missense mutation of BIRC3 gene: a case report

artículo científico publicado en 2016

Metabolic Detection of Bruton's Tyrosine Kinase Inhibition in Mantle Cell Lymphoma Cells

artículo científico publicado en 2019

MicroRNA expression in early mycosis fungoides is distinctly different from atopic dermatitis and advanced cutaneous T-cell lymphoma

artículo científico publicado en 2014

Multilevel dysregulation of STAT3 activation in anaplastic lymphoma kinase-positive T/null-cell lymphoma

artículo científico publicado en 2002

Natural killer-like T-cell lymphoma of the small intestine with a distinct immunophenotype and lack of association with gluten-sensitive enteropathy

artículo científico publicado en 2003

Nonmalignant T cells stimulate growth of T-cell lymphoma cells in the presence of bacterial toxins

artículo científico publicado en 2006

Normal ABL1 is a tumor suppressor and therapeutic target in human and mouse leukemias expressing oncogenic ABL1 kinases

artículo científico publicado en 2016

Nuclear accumulation of cyclin D1 during S phase inhibits Cul4-dependent Cdt1 proteolysis and triggers p53-dependent DNA rereplication

artículo científico publicado en 2007

Nucleophosmin-anaplastic lymphoma kinase: the ultimate oncogene and therapeutic target

Nucleophosmin/anaplastic lymphoma kinase (NPM/ALK) oncoprotein induces the T regulatory cell phenotype by activating STAT3

artículo científico publicado en 2006

Oncogenic kinase NPM/ALK induces through STAT3 expression of immunosuppressive protein CD274 (PD-L1, B7-H1).

scholarly article

Oncogenic tyrosine kinase NPM-ALK induces expression of the growth-promoting receptor ICOS

artículo científico publicado en 2011

Overcoming the Immunosuppressive Tumor Microenvironment of Hodgkin Lymphoma Using Chimeric Antigen Receptor T Cells.

artículo científico publicado en 2017

PRMT5 is required for lymphomagenesis triggered by multiple oncogenic drivers

artículo científico publicado en 2015

PU.1 activates transcription of SHP-1 gene in hematopoietic cells

artículo científico publicado en 2007

Patterns of immune checkpoint protein expression in MYC-overexpressing aggressive B-cell non-Hodgkin lymphomas

artículo científico publicado en 2020

Peroxisome proliferator-activated receptor gamma promotes lymphocyte survival through its actions on cellular metabolic activities

artículo científico publicado en 2006

Persistence of long-lived plasma cells and humoral immunity in individuals responding to CD19-directed CAR T-cell therapy

scientific article published on 10 May 2016

Personalized synthetic lethality induced by targeting RAD52 in leukemias identified by gene mutation and expression profile

artículo científico publicado en 2013

Posttransplantation lymphoproliferative disease with features of lymphomatoid granulomatosis in a lung transplant patient

scientific article published on 01 April 2006

Posttransplantation lymphoproliferative disorder of the paranasal sinuses mimicking invasive fungal sinusitis: case report

scientific article published on 01 May 2002

Prediction and Early Detection of Response by NMR Spectroscopy and Imaging

artículo científico publicado en 2012

Programmed cell death-10 enhances proliferation and protects malignant T cells from apoptosis

artículo científico publicado en 2010

Progressive epidermotropic CD8+/CD4- primary cutaneous CD30+ lymphoproliferative disorder in a patient with sarcoidosis

Retracted: Simultaneous Inhibition of mTOR-Containing Complex 1 (mTORC1) and MNK Induces Apoptosis of Cutaneous T-Cell Lymphoma (CTCL) Cells

artículo científico publicado en 2011

Ruxolitinib-induced defects in DNA repair cause sensitivity to PARP inhibitors in myeloproliferative neoplasms.

artículo científico publicado en 2017

SHP2 regulates IL-2 induced MAPK activation, but not Stat3 or Stat5 tyrosine phosphorylation, in cutaneous T cell lymphoma cells

artículo científico publicado en 2002

STAT3 activation and infiltration of eosinophil granulocytes in mycosis fungoides.

artículo científico publicado en 2014

STAT3 induces transcription of the DNA methyltransferase 1 gene (DNMT1) in malignant T lymphocytes

artículo científico publicado en 2006

STAT3- and DNA methyltransferase 1-mediated epigenetic silencing of SHP-1 tyrosine phosphatase tumor suppressor gene in malignant T lymphocytes

artículo científico publicado en 2005

STAT5 induces miR-21 expression in cutaneous T cell lymphoma.

artículo científico publicado en 2016

STAT5-mediated expression of oncogenic miR-155 in cutaneous T-cell lymphoma

artículo científico publicado en 2013

STAT5A is epigenetically silenced by the tyrosine kinase NPM1-ALK and acts as a tumor suppressor by reciprocally inhibiting NPM1-ALK expression

artículo científico publicado en 2007

Simultaneous Targeting of PARP1 and RAD52 Triggers Dual Synthetic Lethality in BRCA-Deficient Tumor Cells.

artículo científico publicado en 2018

Special AT rich-binding1 protein (SATB1) in malignant T cells.

artículo científico publicado en 2018

Staphylococcal enterotoxin A (SEA) stimulates STAT3 activation and IL-17 expression in cutaneous T-cell lymphoma

artículo científico publicado en 2016

Staphylococcal enterotoxins stimulate lymphoma-associated immune dysregulation.

artículo científico publicado en 2014

Staphylococcus aureus enterotoxins induce FOXP3 in neoplastic T cells in Sézary syndrome

artículo científico publicado en 2020

Successful treatment of T-cell post-transplant lymphoproliferative disorder with the retinoid analog bexarotene

artículo científico publicado en 2005

Successful treatment of relapsed lymphomatoid granulomatosis with bexarotene

artículo científico publicado en 2008

Successful use of the anti-CD25 antibody daclizumab in an adult patient with hemophagocytic lymphohistiocytosis

artículo científico publicado en 2008

TGFβR-SMAD3 Signaling Induces Resistance to PARP Inhibitors in the Bone Marrow Microenvironment

artículo científico publicado en 2020

Targeting CD30 in malignant tissues: challenges in detection and clinical applications

artículo científico

The Addition of the BTK Inhibitor Ibrutinib to Anti-CD19 Chimeric Antigen Receptor T Cells (CART19) Improves Responses against Mantle Cell Lymphoma.

artículo científico publicado en 2016

The Expression of IL-21 Is Promoted by MEKK4 in Malignant T Cells and Associated with Increased Progression Risk in Cutaneous T-Cell Lymphoma.

artículo científico publicado en 2016

The Fbx4 Tumor Suppressor Regulates Cyclin D1 Accumulation and Prevents Neoplastic Transformation

artículo científico publicado el 12 de septiembre de 2011

The combination of IL-21 and IFN-alpha boosts STAT3 activation, cytotoxicity and experimental tumor therapy

artículo científico publicado en 2008

The potent oncogene NPM-ALK mediates malignant transformation of normal human CD4(+) T lymphocytes

artículo científico publicado en 2013

The role of cytokine signaling in the pathogenesis of cutaneous T-cell lymphoma

artículo científico publicado el 15 de diciembre de 2011

Transcriptional repressor domain of MBD1 is intrinsically disordered and interacts with its binding partners in a selective manner

artículo científico publicado en 2014

Transdifferentiation of lymphoma into sarcoma associated with profound reprogramming of epigenome

artículo científico publicado en 2020

Treatment of primary Epstein-Barr virus infection in patients with X-linked lymphoproliferative disease using B-cell-directed therapy

artículo científico publicado en 2004

Tyrosine kinase inhibitor-induced defects in DNA repair sensitize FLT3(ITD)-positive leukemia cells to PARP1 inhibitors.

artículo científico publicado en 2018

Validation of a diagnostic microRNA classifier in cutaneous T-cell lymphomas

artículo científico publicado en 2013

Vascular endothelial growth factor receptor-3 expression in mycosis fungoides

artículo científico publicado en 2012

Whole Exome Sequencing reveals NOTCH1 mutations in anaplastic large cell lymphoma and points to Notch both as a key pathway and a potential therapeutic target

artículo científico publicado en 2020