Lista de obras -

A Comparison of Whole Genome Sequencing of SARS-CoV-2 Using Amplicon-Based Sequencing, Random Hexamers, and Bait Capture

artículo científico publicado en 2020

A Lymphotoxin/Type I IFN Axis Programs CD8+ T Cells To Infiltrate a Self-Tissue and Propagate Immunopathology

artículo científico publicado en 2015

A critical role for IL-15 in TLR-mediated innate antiviral immunity against genital HSV-2 infection.

artículo científico publicado en 2011

AHR signaling is induced by infection with coronaviruses

artículo científico publicado en 2021

Activation and inhibition of virus and interferon: the herpesvirus story

artículo científico publicado en 2002

Active-site mTOR inhibitors augment HSV1-dICP0 infection in cancer cells via dysregulated eIF4E/4E-BP axis

scientific article published on 23 August 2018

Adaptive antiviral immunity is a determinant of the therapeutic success of oncolytic virotherapy

artículo científico publicado en 2010

An accessory to the 'Trinity': SR-As are essential pathogen sensors of extracellular dsRNA, mediating entry and leading to subsequent type I IFN responses

artículo científico publicado en 2010

Analysis of anti-interferon properties of the herpes simplex virus type I ICP0 protein

artículo científico publicado en 2005

Anti-NMDA receptor encephalitis. The disorder, the diagnosis and the immunobiology.

artículo científico publicado en 2012

Antigen presentation by exosomes released from peptide-pulsed dendritic cells is not suppressed by the presence of active CTL.

artículo científico publicado en 2007

Bat Influenza Viruses: Making a Double Agent of MHC Class II

artículo científico publicado en 2020

Bats and Coronaviruses

artículo científico publicado en 2019

Cell fusion-induced activation of interferon-stimulated genes is not required for restriction of a herpes simplex virus VP16/ICP0 mutant in heterokarya formed between permissive and restrictive cells.

artículo científico publicado en 2009

Cellular Protein WDR11 Interacts with Specific Herpes Simplex Virus Proteins at the trans-Golgi Network To Promote Virus Replication

artículo científico publicado en 2015

Cellular localization of the herpes simplex virus ICP0 protein dictates its ability to block IRF3-mediated innate immune responses

artículo científico publicado en 2010

Characterization of the interferon regulatory factor 3-mediated antiviral response in a cell line deficient for IFN production

artículo científico publicado en 2008

Cigarette smoke attenuation of poly I:C-induced innate antiviral responses in human PBMC is mainly due to inhibition of IFN-beta production.

artículo científico publicado en 2008

Cigarette smoke suppresses type I interferon-mediated antiviral immunity in lung fibroblast and epithelial cells.

artículo científico publicado en 2008

Class A Scavenger Receptor-Mediated Double-Stranded RNA Internalization Is Independent of Innate Antiviral Signaling and Does Not Require Phosphatidylinositol 3-Kinase Activity

artículo científico publicado en 2015

Combining oncolytic HSV-1 with immunogenic cell death-inducing drug mitoxantrone breaks cancer immune tolerance and improves therapeutic efficacy

artículo científico publicado en 2013

Commentary: Phyllostomid bat microbiome composition is associated to host phylogeny and feeding strategies

article

Comparative functional evaluation of immunocompetent mouse breast cancer models established from PyMT-tumors using small animal PET with [(18)F]FDG and [(18)F]FLT ⬇️

artículo científico publicado el 15 de diciembre de 2011

Consensus guidelines for the definition, detection and interpretation of immunogenic cell death

scientific article published on 01 March 2020

Consensus guidelines for the detection of immunogenic cell death

artículo científico publicado en 2014

Critical Interactions between Immunogenic Cancer Cell Death, Oncolytic Viruses, and the Immune System Define the Rational Design of Combination Immunotherapies

artículo científico publicado en 2018

Cutting edge: FimH adhesin of type 1 fimbriae is a novel TLR4 ligand.

artículo científico publicado en 2008

Danger, diversity and priming in innate antiviral immunity.

artículo científico

De novo necroptosis creates an inflammatory environment mediating tumor susceptibility to immune checkpoint inhibitors

scientific article published on 04 November 2020

Detecting single cell interferon-beta production using a fluorescent reporter telomerase-immortalized human fibroblast cell line

artículo científico publicado en 2021

Differential modification of interferon regulatory factor 3 following virus particle entry

artículo científico publicado en 2009

Direct binding and internalization of diverse extracellular nucleic acid species through the collagenous domain of class A scavenger receptors.

artículo científico publicado en 2018

Discovery and Use of Long dsRNA Mediated RNA Interference to Stimulate Antiviral Protection in Interferon Competent Mammalian Cells

artículo científico publicado en 2022

Distinct functional motifs within the IL-17 receptor regulate signal transduction and target gene expression

artículo científico publicado en 2007

Enhanced efficacy with azacytidine and oncolytic BHV-1 in a tolerized cotton rat model of breast adenocarcinoma

artículo científico publicado en 2015

Erratum: USP15 regulates type I interferon response and is required for pathogenesis of neuroinflammation.

artículo científico publicado en 2016

Experimental and natural evidence of SARS-CoV-2 infection-induced activation of type I interferon responses

Experimental and natural evidence of SARS-CoV-2-infection-induced activation of type I interferon responses

artículo científico publicado en 2021

Exposure to cigarette smoke suppresses IL-15 generation and its regulatory NK cell functions in poly I:C-augmented human PBMCs.

artículo científico publicado en 2009

Extracellular dsRNA: its function and mechanism of cellular uptake

artículo científico publicado en 2014

FimH adhesin of type 1 fimbriae is a potent inducer of innate antimicrobial responses which requires TLR4 and type 1 interferon signalling

artículo científico publicado en 2008

Functional inaccessibility of quiescent herpes simplex virus genomes

artículo científico publicado en 2005

Gene expression and in situ protein profiling of candidate SARS-CoV-2 receptors in human airway epithelial cells and lung tissue

artículo científico publicado en 2020

Gene expression and in situ protein profiling of candidate SARS-CoV-2 receptors in human airway epithelial cells and lung tissue

scientific article published on 16 July 2020

Genetic modification of oncolytic viruses to enhance antitumor immunity

artículo científico publicado en 2019

HIV-1 gp120 induces TLR2- and TLR4-mediated innate immune activation in human female genital epithelium

artículo científico publicado en 2013

HSV cheats the executioner

artículo científico publicado en 2015

Handling of the cotton rat in studies for the pre-clinical evaluation of oncolytic viruses

artículo científico publicado en 2014

Herpes simplex virus 1 tegument protein US11 downmodulates the RLR signaling pathway via direct interaction with RIG-I and MDA-5

artículo científico publicado en 2012

Herpes simplex virus ICP0 and ICP34.5 counteract distinct interferon-induced barriers to virus replication

artículo científico publicado en 2002

Herpesviruses and the innate immune response.

artículo científico publicado en 2005

Hypoxia-Driven Immune Escape in the Tumor Microenvironment

scientific article published on 16 April 2020

ICP0 prevents RNase L-independent rRNA cleavage in herpes simplex virus type 1-infected cells

artículo científico publicado en 2006

IL-15 and IFN-γ signal through the ERK pathway to inhibit HCV replication, independent of type I IFN signaling

artículo científico publicado en 2018

IL-15 and type I interferon are required for activation of tumoricidal NK cells by virus-infected dendritic cells

artículo científico publicado en 2011

Identification of a novel pathway essential for the immediate-early, interferon-independent antiviral response to enveloped virions

artículo científico publicado en 2006

Immune checkpoint blockade in triple negative breast cancer influenced by B cells through myeloid-derived suppressor cells

artículo científico publicado en 2021

Immunogenic HSV-mediated oncolysis shapes the antitumor immune response and contributes to therapeutic efficacy

artículo científico publicado en 2013

Impairment of human NK cell cytotoxic activity and cytokine release by cigarette smoke.

artículo científico publicado en 2007

Induction of innate immunity against herpes simplex virus type 2 infection via local delivery of Toll-like receptor ligands correlates with beta interferon production.

artículo científico publicado en 2006

Inflammatory monocytes require type I interferon receptor signaling to activate NK cells via IL-18 during a mucosal viral infection

artículo científico publicado en 2017

Innate and Adaptive Immune Responses to Herpes Simplex Virus ⬇️

artículo científico publicado el 18 de noviembre de 2009

Innate cellular response to virus particle entry requires IRF3 but not virus replication

artículo científico publicado en 2004

Interferon-Dependent Induction of Clr-b during Mouse Cytomegalovirus Infection Protects Bystander Cells from Natural Killer Cells via NKR-P1B-Mediated Inhibition.

artículo científico publicado en 2017

Isolation, Sequence, Infectivity, and Replication Kinetics of Severe Acute Respiratory Syndrome Coronavirus 2

scientific article published on 19 June 2020

Long double-stranded RNA induces an antiviral response independent of IFN regulatory factor 3, IFN-beta promoter stimulator 1, and IFN

artículo científico publicado en 2009

MARCO is required for TLR2- and Nod2-mediated responses to Streptococcus pneumoniae and clearance of pneumococcal colonization in the murine nasopharynx.

artículo científico publicado en 2012

Mechanisms employed by herpes simplex virus 1 to inhibit the interferon response

scientific article published on September 2009

Mechanistic insights into COVID-19 by global analysis of the SARS-CoV-2 3CL substrate degradome

artículo científico publicado en 2021

Membrane Perturbation Elicits an IRF3-Dependent, Interferon-Independent Antiviral Response ⬇️

artículo científico publicado el 3 de agosto de 2011

Membrane Perturbation-Associated Ca2+ Signaling and Incoming Genome Sensing Are Required for the Host Response to Low-Level Enveloped Virus Particle Entry

artículo científico publicado en 2015

Methods related to molecular virology

artículo científico publicado en 2015

Methods related to molecular virology

artículo científico publicado en 2011

Molecular Pathogenesis of Middle East Respiratory Syndrome (MERS) Coronavirus

artículo científico publicado en 2019

Novel Insights Into Immune Systems of Bats

scientific article published on 24 January 2020

Novel paradigms of innate immune sensing of viral infections

artículo científico publicado en 2013

Novel roles of cytoplasmic ICP0: proteasome-independent functions of the RING finger are required to block interferon-stimulated gene production but not to promote viral replication

artículo científico publicado en 2014

Oncolytic bovine herpesvirus type 1 as a broad spectrum cancer therapeutic.

artículo científico

Oncolytic virotherapy and immunogenic cancer cell death: sharpening the sword for improved cancer treatment strategies

artículo científico publicado en 2013

Oncolytic viruses: how "lytic" must they be for therapeutic efficacy?

artículo científico publicado en 2019

Open drug discovery of anti-virals critical for Canada’s pandemic strategy

artículo científico publicado en 2020

Permissiveness of human cancer cells to oncolytic bovine herpesvirus 1 is mediated in part by KRAS activity ⬇️

artículo científico publicado en 2014

Positive Selection of a Serine Residue in Bat IRF3 Confers Enhanced Antiviral Protection

scientific article published on 02 March 2020

Pre-surgical neoadjuvant oncolytic virotherapy confers protection against rechallenge in a murine model of breast cancer

artículo científico publicado en 2019

Predicting the recombination potential of severe acute respiratory syndrome coronavirus 2 and Middle East respiratory syndrome coronavirus

artículo científico publicado en 2020

Proinflammatory Cytokines and Chemokines - But not Interferon-β - Produced in Response to HSV-2 in Primary Human Genital Epithelial Cells are Associated with Viral Replication and the Presence of the Virion Host Shutoff Protein ⬇️

artículo científico publicado el 29 de abril de 2013

Recent advances in understanding viral evasion of type I interferon ⬇️

artículo científico publicado el 1 de marzo de 2013

Recognition of virus infection and innate host responses to viral gene therapy vectors

artículo científico publicado en 2010

Replication of subgenomic hepatitis C virus replicons in mouse fibroblasts is facilitated by deletion of interferon regulatory factor 3 and expression of liver-specific microRNA 122

artículo científico publicado en 2010

Restoration of vitamin C synthesis in transgenic Gulo-/- mice by helper-dependent adenovirus-based expression of gulonolactone oxidase

artículo científico publicado en 2008

Retroviral expression of MIR2 decreases both surface MHC class I and the alloimmune CTL response ⬇️

artículo científico publicado el 10 de enero de 2011

Rewiring cancer cell death to enhance oncolytic viro-immunotherapy

artículo científico publicado en 2013

S6K-STING interaction regulates cytosolic DNA-mediated activation of the transcription factor IRF3.

artículo científico publicado en 2016

Sequence, infectivity and replication kinetics of SARS-CoV-2 isolated from COVID-19 patients in Canada

artículo científico publicado en 2020

Seroprevalence in Bats and Detection of Borrelia burgdorferi in Bat Ectoparasites

artículo científico publicado en 2020

Studies of immunosuppressive poxviruses.

The IFN-independent response to virus particle entry provides a first line of antiviral defense that is independent of TLRs and retinoic acid-inducible gene I.

artículo científico publicado en 2006

The Importance of Physiologically Relevant Cell Lines for Studying Virus-Host Interactions

artículo científico publicado en 2016

The herpes simplex virus 1-encoded envelope glycoprotein B activates NF-κB through the Toll-like receptor 2 and MyD88/TRAF6-dependent signaling pathway

artículo científico publicado en 2013

The herpes simplex virus ICP0 RING finger domain inhibits IRF3- and IRF7-mediated activation of interferon-stimulated genes

artículo científico publicado en 2004

The nitric oxide pathway provides innate antiviral protection in conjunction with the type I interferon pathway in fibroblasts

artículo científico publicado en 2012

The role of ICP0-Null HSV-1 and interferon signaling defects in the effective treatment of breast adenocarcinoma.

artículo científico publicado en 2005

The role of oncolytic virus immunotherapies to subvert cancer immune evasion

artículo científico publicado en 2015

The role of palmitoylation for protein recruitment to the inner membrane complex of the malaria parasite

artículo científico publicado en 2015

Treating viral exacerbations of chronic obstructive pulmonary disease: insights from a mouse model of cigarette smoke and H1N1 influenza infection

artículo científico publicado en 2010

Trial Watch: Oncolytic viro-immunotherapy of hematologic and solid tumors

artículo científico publicado en 2018

Type I Interferon Induced by Streptococcus suis Serotype 2 is Strain-Dependent and May Be Beneficial for Host Survival

artículo científico publicado en 2017

Type I interferon restricts type 2 immunopathology through the regulation of group 2 innate lymphoid cells

artículo científico publicado en 2015

Type-I interferon signaling through ISGF3 complex is required for sustained Rip3 activation and necroptosis in macrophages.

artículo científico publicado en 2014

USP15 regulates type I interferon response and is required for pathogenesis of neuroinflammation

artículo científico publicado en 2016

Unraveling the Zoonotic Origin and Transmission of SARS-CoV-2

artículo científico publicado en 2020

Varicella-zoster virus immediate-early protein ORF61 abrogates the IRF3-mediated innate immune response through degradation of activated IRF3

artículo científico publicado en 2011

Virus-Intrinsic Differences and Heterogeneous IRF3 Activation Influence IFN-Independent Antiviral Protection

artículo científico publicado en 2020

Widely Used Herpes Simplex Virus 1 ICP0 Deletion Mutant Strain dl1403 and Its Derivative Viruses Do Not Express Glycoprotein C Due to a Secondary Mutation in the gC Gene

artículo científico publicado en 2015

Zooanthroponotic potential of SARS-CoV-2 and implications of reintroduction into human populations

publication published on 13 January 2021

Lista de obras de

A Comparison of Whole Genome Sequencing of SARS-CoV-2 Using Amplicon-Based Sequencing, Random Hexamers, and Bait Capture

A Lymphotoxin/Type I IFN Axis Programs CD8+ T Cells To Infiltrate a Self-Tissue and Propagate Immunopathology

A critical role for IL-15 in TLR-mediated innate antiviral immunity against genital HSV-2 infection.

AHR signaling is induced by infection with coronaviruses

Activation and inhibition of virus and interferon: the herpesvirus story

Active-site mTOR inhibitors augment HSV1-dICP0 infection in cancer cells via dysregulated eIF4E/4E-BP axis

Adaptive antiviral immunity is a determinant of the therapeutic success of oncolytic virotherapy

An accessory to the 'Trinity': SR-As are essential pathogen sensors of extracellular dsRNA, mediating entry and leading to subsequent type I IFN responses

Analysis of anti-interferon properties of the herpes simplex virus type I ICP0 protein

Anti-NMDA receptor encephalitis. The disorder, the diagnosis and the immunobiology.

Antigen presentation by exosomes released from peptide-pulsed dendritic cells is not suppressed by the presence of active CTL.

Bat Influenza Viruses: Making a Double Agent of MHC Class II

Bats and Coronaviruses

Cell fusion-induced activation of interferon-stimulated genes is not required for restriction of a herpes simplex virus VP16/ICP0 mutant in heterokarya formed between permissive and restrictive cells.

Cellular Protein WDR11 Interacts with Specific Herpes Simplex Virus Proteins at the trans-Golgi Network To Promote Virus Replication

Cellular localization of the herpes simplex virus ICP0 protein dictates its ability to block IRF3-mediated innate immune responses

Characterization of the interferon regulatory factor 3-mediated antiviral response in a cell line deficient for IFN production

Cigarette smoke attenuation of poly I:C-induced innate antiviral responses in human PBMC is mainly due to inhibition of IFN-beta production.

Cigarette smoke suppresses type I interferon-mediated antiviral immunity in lung fibroblast and epithelial cells.

Class A Scavenger Receptor-Mediated Double-Stranded RNA Internalization Is Independent of Innate Antiviral Signaling and Does Not Require Phosphatidylinositol 3-Kinase Activity

Combining oncolytic HSV-1 with immunogenic cell death-inducing drug mitoxantrone breaks cancer immune tolerance and improves therapeutic efficacy

Commentary: Phyllostomid bat microbiome composition is associated to host phylogeny and feeding strategies

Comparative functional evaluation of immunocompetent mouse breast cancer models established from PyMT-tumors using small animal PET with [(18)F]FDG and [(18)F]FLT ⬇️

Consensus guidelines for the definition, detection and interpretation of immunogenic cell death

Consensus guidelines for the detection of immunogenic cell death

Critical Interactions between Immunogenic Cancer Cell Death, Oncolytic Viruses, and the Immune System Define the Rational Design of Combination Immunotherapies

Cutting edge: FimH adhesin of type 1 fimbriae is a novel TLR4 ligand.

Danger, diversity and priming in innate antiviral immunity.

De novo necroptosis creates an inflammatory environment mediating tumor susceptibility to immune checkpoint inhibitors

Detecting single cell interferon-beta production using a fluorescent reporter telomerase-immortalized human fibroblast cell line

Differential modification of interferon regulatory factor 3 following virus particle entry

Direct binding and internalization of diverse extracellular nucleic acid species through the collagenous domain of class A scavenger receptors.

Discovery and Use of Long dsRNA Mediated RNA Interference to Stimulate Antiviral Protection in Interferon Competent Mammalian Cells

Distinct functional motifs within the IL-17 receptor regulate signal transduction and target gene expression

Enhanced efficacy with azacytidine and oncolytic BHV-1 in a tolerized cotton rat model of breast adenocarcinoma

Erratum: USP15 regulates type I interferon response and is required for pathogenesis of neuroinflammation.

Experimental and natural evidence of SARS-CoV-2 infection-induced activation of type I interferon responses

Experimental and natural evidence of SARS-CoV-2-infection-induced activation of type I interferon responses

Exposure to cigarette smoke suppresses IL-15 generation and its regulatory NK cell functions in poly I:C-augmented human PBMCs.

Extracellular dsRNA: its function and mechanism of cellular uptake

FimH adhesin of type 1 fimbriae is a potent inducer of innate antimicrobial responses which requires TLR4 and type 1 interferon signalling

Functional inaccessibility of quiescent herpes simplex virus genomes

Gene expression and in situ protein profiling of candidate SARS-CoV-2 receptors in human airway epithelial cells and lung tissue

Gene expression and in situ protein profiling of candidate SARS-CoV-2 receptors in human airway epithelial cells and lung tissue

Genetic modification of oncolytic viruses to enhance antitumor immunity

HIV-1 gp120 induces TLR2- and TLR4-mediated innate immune activation in human female genital epithelium

HSV cheats the executioner

Handling of the cotton rat in studies for the pre-clinical evaluation of oncolytic viruses

Herpes simplex virus 1 tegument protein US11 downmodulates the RLR signaling pathway via direct interaction with RIG-I and MDA-5

Herpes simplex virus ICP0 and ICP34.5 counteract distinct interferon-induced barriers to virus replication

Herpesviruses and the innate immune response.

Hypoxia-Driven Immune Escape in the Tumor Microenvironment

ICP0 prevents RNase L-independent rRNA cleavage in herpes simplex virus type 1-infected cells

IL-15 and IFN-γ signal through the ERK pathway to inhibit HCV replication, independent of type I IFN signaling

IL-15 and type I interferon are required for activation of tumoricidal NK cells by virus-infected dendritic cells

Identification of a novel pathway essential for the immediate-early, interferon-independent antiviral response to enveloped virions

Immune checkpoint blockade in triple negative breast cancer influenced by B cells through myeloid-derived suppressor cells

Immunogenic HSV-mediated oncolysis shapes the antitumor immune response and contributes to therapeutic efficacy

Impairment of human NK cell cytotoxic activity and cytokine release by cigarette smoke.

Induction of innate immunity against herpes simplex virus type 2 infection via local delivery of Toll-like receptor ligands correlates with beta interferon production.

Inflammatory monocytes require type I interferon receptor signaling to activate NK cells via IL-18 during a mucosal viral infection

Innate and Adaptive Immune Responses to Herpes Simplex Virus ⬇️

Innate cellular response to virus particle entry requires IRF3 but not virus replication

Interferon-Dependent Induction of Clr-b during Mouse Cytomegalovirus Infection Protects Bystander Cells from Natural Killer Cells via NKR-P1B-Mediated Inhibition.

Isolation, Sequence, Infectivity, and Replication Kinetics of Severe Acute Respiratory Syndrome Coronavirus 2

Long double-stranded RNA induces an antiviral response independent of IFN regulatory factor 3, IFN-beta promoter stimulator 1, and IFN

MARCO is required for TLR2- and Nod2-mediated responses to Streptococcus pneumoniae and clearance of pneumococcal colonization in the murine nasopharynx.

Mechanisms employed by herpes simplex virus 1 to inhibit the interferon response

Mechanistic insights into COVID-19 by global analysis of the SARS-CoV-2 3CL substrate degradome

Membrane Perturbation Elicits an IRF3-Dependent, Interferon-Independent Antiviral Response ⬇️

Membrane Perturbation-Associated Ca2+ Signaling and Incoming Genome Sensing Are Required for the Host Response to Low-Level Enveloped Virus Particle Entry

Methods related to molecular virology

Methods related to molecular virology

Molecular Pathogenesis of Middle East Respiratory Syndrome (MERS) Coronavirus

Novel Insights Into Immune Systems of Bats

Novel paradigms of innate immune sensing of viral infections

Novel roles of cytoplasmic ICP0: proteasome-independent functions of the RING finger are required to block interferon-stimulated gene production but not to promote viral replication

Oncolytic bovine herpesvirus type 1 as a broad spectrum cancer therapeutic.

Oncolytic virotherapy and immunogenic cancer cell death: sharpening the sword for improved cancer treatment strategies