Lista de obras -

(18)F-Based Pretargeted PET Imaging Based on Bioorthogonal Diels-Alder Click Chemistry.

artículo científico

89Zr-Labeled AR20.5: A MUC1-Targeting ImmunoPET Probe

scientific article published on 15 May 2020

A Bone-Seeking trans-Cyclooctene for Pretargeting and Bioorthogonal Chemistry: A Proof of Concept Study Using 99mTc- and 177Lu-Labeled Tetrazines.

artículo científico publicado en 2016

A Bulky Rhodium Complex Bound to an Adenosine-Adenosine DNA Mismatch: General Architecture of the Metalloinsertion Binding Mode

artículo científico publicado en 2009

A Molecularly Targeted Intraoperative Near-Infrared Fluorescence Imaging Agent for High-Grade Serous Ovarian Cancer

scientific article published on 16 July 2020

A Novel Technique for Generating and Observing Chemiluminescence in a Biological Setting

artículo científico publicado en 2017

A Pretargeted Approach for the Multimodal PET/NIRF Imaging of Colorectal Cancer. ⬇️

artículo científico publicado en 2016

A brief overview of metal complexes as nuclear imaging agents

artículo científico publicado en 2019

A comparative evaluation of the chelators H4octapa and CHX-A″-DTPA with the therapeutic radiometal (90)Y.

artículo científico publicado en 2016

A mismatch-selective bifunctional rhodium-Oregon Green conjugate: a fluorescent probe for mismatched DNA.

artículo científico publicado en 2006

A practical guide to the construction of radiometallated bioconjugates for positron emission tomography.

artículo científico publicado en 2011

A pretargeted PET imaging strategy based on bioorthogonal Diels-Alder click chemistry.

artículo científico publicado en 2013

Alternative chelator for ⁸⁹Zr radiopharmaceuticals: radiolabeling and evaluation of 3,4,3-(LI-1,2-HOPO).

artículo científico publicado en 2014

Binding of Ru(bpy)2(eilatin)2+ to matched and mismatched DNA.

artículo científico publicado en 2008

Building Blocks for the Construction of Bioorthogonally Reactive Peptides via Solid-Phase Peptide Synthesis.

artículo científico publicado en 2014

Chemoenzymatic strategy for the synthesis of site-specifically labeled immunoconjugates for multimodal PET and optical imaging

artículo científico publicado en 2014

Click Chemistry and Radiochemistry: The First 10 Years

artículo científico publicado en 2016

Click-Mediated Pretargeted Radioimmunotherapy of Colorectal Carcinoma.

artículo científico publicado en 2018

DNA base mismatch detection with bulky rhodium intercalators: synthesis and applications

artículo científico publicado en 2007

Dendrimer Scaffold for the Amplification of In Vivo Pretargeting Ligations.

artículo científico publicado en 2018

Design and synthesis of promiscuous high-affinity monoamine transporter ligands: unraveling transporter selectivity

artículo científico publicado en 2006

DiPODS: A Reagent for Site-Specific Bioconjugation via the Irreversible Rebridging of Disulfide Linkages

artículo científico publicado en 2020

Dual Radionuclide Theranostic Pretargeting

scientific article published on 09 September 2019

ESPMIS: Helping Young Scientists Navigate the Molecular Imaging Landscape.

artículo científico publicado en 2017

Enzyme-mediated methodology for the site-specific radiolabeling of antibodies based on catalyst-free click chemistry

artículo científico publicado en 2013

Establishment of the In Vivo Efficacy of Pretargeted Radioimmunotherapy Utilizing Inverse Electron Demand Diels-Alder Click Chemistry

artículo científico publicado en 2016

Exploring Structural Parameters for Pretargeting Radioligand Optimization

artículo científico publicado en 2017

Fc-mediated Anomalous Biodistribution of Therapeutic Antibodies in Immunodeficient Mouse Models.

artículo científico publicado en 2018

First-in-human HER2-targeted imaging using 89Zr-pertuzumab PET/CT: Dosimetry and clinical application in patients with breast cancer

artículo científico publicado en 2017

H(2)azapa: a versatile acyclic multifunctional chelator for (67)Ga, (64)Cu, (111)In, and (177)Lu

artículo científico publicado en 2012

H(4)octapa-trastuzumab: versatile acyclic chelate system for 111In and 177Lu imaging and therapy

artículo científico publicado en 2013

H6phospa-trastuzumab: bifunctional methylenephosphonate-based chelator with 89Zr, 111In and 177Lu.

scientific article published on January 2014

Harnessing 64Cu/67Cu for a theranostic approach to pretargeted radioimmunotherapy

artículo científico publicado en 2020

Harnessing the bioorthogonal inverse electron demand Diels-Alder cycloaddition for pretargeted PET imaging

artículo científico publicado en 2015

Identification of HER2-Positive Metastases in Patients with HER2-Negative Primary Breast Cancer by Using HER2-targeted 89Zr-Pertuzumab PET/CT

artículo científico publicado en 2020

Inverse electron demand Diels–Alder click chemistry for pretargeted PET imaging and radioimmunotherapy

artículo científico publicado en 2021

Leveraging bioorthogonal click chemistry to improve 225Ac-radioimmunotherapy of pancreatic ductal adenocarcinoma

scientific article published on 23 October 2018

Manipulating the In Vivo Behaviour of 68Ga with Tris(Hydroxypyridinone) Chelators: Pretargeting and Blood Clearance

artículo científico publicado en 2020

Metallo-intercalators and metallo-insertors

artículo científico publicado en 2007

Modular strategy for the construction of radiometalated antibodies for positron emission tomography based on inverse electron demand Diels-Alder click chemistry

artículo científico publicado en 2011

Molecular Imaging of Ovarian Cancer

artículo científico publicado en 2016

Near-Infrared Intraoperative Chemiluminescence Imaging

artículo científico publicado en 2016

Noninvasive Interrogation of DLL3 Expression in Metastatic Small Cell Lung Cancer

artículo científico publicado en 2017

On the consensus nomenclature rules for radiopharmaceutical chemistry - Reconsideration of radiochemical conversion

artículo científico publicado en 2020

Optimization of a Pretargeted Strategy for the PET Imaging of Colorectal Carcinoma via the Modulation of Radioligand Pharmacokinetics.

artículo científico publicado en 2015

PARP1-Targeted Radiotherapy in Mouse Models of Glioblastoma.

artículo científico publicado en 2018

PET imaging with ⁸⁹Zr: from radiochemistry to the clinic

artículo científico publicado en 2012

Poly(ADP-Ribose)Polymerase (PARP) Inhibitors and Radiation Therapy

artículo científico publicado en 2020

Preclinical 89Zr Immuno-PET of High-Grade Serous Ovarian Cancer and Lymph Node Metastasis.

artículo científico publicado en 2016

Pretargeted Imaging and Therapy

artículo científico publicado en 2017

Pretargeted Immuno-PET of Pancreatic Cancer: Overcoming Circulating Antigen and Internalized Antibody to Reduce Radiation Doses

artículo científico publicado en 2015

Pretargeted PET Imaging Using a Site-Specifically Labeled Immunoconjugate

scientific article published on 29 June 2016

Pretargeted Radioimmunotherapy Based on the Inverse Electron Demand Diels-Alder Reaction

artículo científico publicado en 2019

Pretargeted radioimmunotherapy and SPECT imaging of peritoneal carcinomatosis using bioorthogonal click chemistry: probe selection and first proof-of-concept

scientific article published on 19 September 2019

Pretargeting of internalizing trastuzumab and cetuximab with a 18F-tetrazine tracer in xenograft models

artículo científico publicado en 2017

Recognition of abasic sites and single base bulges in DNA by a metalloinsertor

scientific article published on February 2009

Removal of Fc Glycans from [89Zr]Zr-DFO-anti-CD8 prevents peripheral depletion of CD8+ T cells

artículo científico publicado en 2020

Role of metalation in the topoisomerase IIα inhibition and antiproliferation activity of a series of α-heterocyclic-N4-substituted thiosemicarbazones and their Cu(II) complexes.

artículo científico publicado en 2011

Site-Specifically Labeled Antibody-Drug Conjugate for Simultaneous Therapy and ImmunoPET.

artículo científico publicado en 2018

Site-Specifically Labeled Immunoconjugates for Molecular Imaging--Part 1: Cysteine Residues and Glycans

artículo científico publicado en 2016

Site-Specifically Labeled Immunoconjugates for Molecular Imaging--Part 2: Peptide Tags and Unnatural Amino Acids

artículo científico publicado en 2016

Site-specifically labeled CA19.9-targeted immunoconjugates for the PET, NIRF, and multimodal PET/NIRF imaging of pancreatic cancer.

artículo científico publicado en 2015

Synthesis and Bioconjugation of Thiol-Reactive Reagents for the Creation of Site-Selectively Modified Immunoconjugates

artículo científico publicado en 2019

Synthesis and evaluation of (18)F-labeled ATP competitive inhibitors of topoisomerase II as probes for imaging topoisomerase II expression.

artículo científico publicado en 2014

Synthesis of the first radiolabeled 188Re N-heterocyclic carbene complex and initial studies on its potential use in radiopharmaceutical applications

artículo científico publicado en 2014

Targeted brain tumor radiotherapy using an Auger emitter

scientific article published on 17 February 2020

Targeting Triple Negative Breast Cancer with a Nucleus-Directed p53 Tetramerization Domain Peptide

artículo científico publicado en 2020

Targeting abasic sites and single base bulges in DNA with metalloinsertors

artículo científico publicado en 2008

The Impact of FcγRI Binding on Immuno-PET

scientific article published on 07 February 2019

The Influence of Glycans-Specific Bioconjugation on the FcγRI Binding and In vivo Performance of 89Zr-DFO-Pertuzumab

artículo científico publicado en 2020

The bioconjugation and radiosynthesis of 89Zr-DFO-labeled antibodies

artículo científico publicado en 2015

The inverse electron demand Diels-Alder click reaction in radiochemistry

artículo científico

The synthesis and evaluation of N1-(4-(2-[18F]-fluoroethyl)phenyl)-N8-hydroxyoctanediamide ([18F]-FESAHA), a PET radiotracer designed for the delineation of histone deacetylase expression in cancer.

artículo científico publicado en 2011

Thiol-Reactive Bifunctional Chelators for the Creation of Site-Selectively Modified Radioimmunoconjugates with Improved Stability.

artículo científico publicado en 2018

Toward the Optimization of Click-Mediated Pretargeted Radioimmunotherapy

artículo científico publicado en 2019

Underscoring the influence of inorganic chemistry on nuclear imaging with radiometals

artículo científico publicado en 2013

Understanding the In Vivo Fate of Radioimmunoconjugates for PET and SPECT.

artículo científico publicado en 2018

Unexpected oxidative C-C cleavage in the metallation of 2-substituted imidazolium salts to give N-heterocyclic carbene complexes.

artículo científico publicado en 2004

What a difference a carbon makes: H₄octapa vs H₄C3octapa, ligands for In-111 and Lu-177 radiochemistry

artículo científico publicado en 2014

Lista de obras de

(18)F-Based Pretargeted PET Imaging Based on Bioorthogonal Diels-Alder Click Chemistry.

89Zr-Labeled AR20.5: A MUC1-Targeting ImmunoPET Probe

A Bone-Seeking trans-Cyclooctene for Pretargeting and Bioorthogonal Chemistry: A Proof of Concept Study Using 99mTc- and 177Lu-Labeled Tetrazines.

A Bulky Rhodium Complex Bound to an Adenosine-Adenosine DNA Mismatch: General Architecture of the Metalloinsertion Binding Mode

A Molecularly Targeted Intraoperative Near-Infrared Fluorescence Imaging Agent for High-Grade Serous Ovarian Cancer

A Novel Technique for Generating and Observing Chemiluminescence in a Biological Setting

A Pretargeted Approach for the Multimodal PET/NIRF Imaging of Colorectal Cancer. ⬇️

A brief overview of metal complexes as nuclear imaging agents

A comparative evaluation of the chelators H4octapa and CHX-A″-DTPA with the therapeutic radiometal (90)Y.

A mismatch-selective bifunctional rhodium-Oregon Green conjugate: a fluorescent probe for mismatched DNA.

A practical guide to the construction of radiometallated bioconjugates for positron emission tomography.

A pretargeted PET imaging strategy based on bioorthogonal Diels-Alder click chemistry.

Alternative chelator for ⁸⁹Zr radiopharmaceuticals: radiolabeling and evaluation of 3,4,3-(LI-1,2-HOPO).

Binding of Ru(bpy)2(eilatin)2+ to matched and mismatched DNA.

Building Blocks for the Construction of Bioorthogonally Reactive Peptides via Solid-Phase Peptide Synthesis.

Chemoenzymatic strategy for the synthesis of site-specifically labeled immunoconjugates for multimodal PET and optical imaging

Click Chemistry and Radiochemistry: The First 10 Years

Click-Mediated Pretargeted Radioimmunotherapy of Colorectal Carcinoma.

DNA base mismatch detection with bulky rhodium intercalators: synthesis and applications

Dendrimer Scaffold for the Amplification of In Vivo Pretargeting Ligations.

Design and synthesis of promiscuous high-affinity monoamine transporter ligands: unraveling transporter selectivity

DiPODS: A Reagent for Site-Specific Bioconjugation via the Irreversible Rebridging of Disulfide Linkages

Dual Radionuclide Theranostic Pretargeting

ESPMIS: Helping Young Scientists Navigate the Molecular Imaging Landscape.

Enzyme-mediated methodology for the site-specific radiolabeling of antibodies based on catalyst-free click chemistry

Establishment of the In Vivo Efficacy of Pretargeted Radioimmunotherapy Utilizing Inverse Electron Demand Diels-Alder Click Chemistry

Exploring Structural Parameters for Pretargeting Radioligand Optimization

Fc-mediated Anomalous Biodistribution of Therapeutic Antibodies in Immunodeficient Mouse Models.

First-in-human HER2-targeted imaging using 89Zr-pertuzumab PET/CT: Dosimetry and clinical application in patients with breast cancer

H(2)azapa: a versatile acyclic multifunctional chelator for (67)Ga, (64)Cu, (111)In, and (177)Lu

H(4)octapa-trastuzumab: versatile acyclic chelate system for 111In and 177Lu imaging and therapy

H6phospa-trastuzumab: bifunctional methylenephosphonate-based chelator with 89Zr, 111In and 177Lu.

Harnessing 64Cu/67Cu for a theranostic approach to pretargeted radioimmunotherapy

Harnessing the bioorthogonal inverse electron demand Diels-Alder cycloaddition for pretargeted PET imaging

Identification of HER2-Positive Metastases in Patients with HER2-Negative Primary Breast Cancer by Using HER2-targeted 89Zr-Pertuzumab PET/CT

Inverse electron demand Diels–Alder click chemistry for pretargeted PET imaging and radioimmunotherapy

Leveraging bioorthogonal click chemistry to improve 225Ac-radioimmunotherapy of pancreatic ductal adenocarcinoma

Manipulating the In Vivo Behaviour of 68Ga with Tris(Hydroxypyridinone) Chelators: Pretargeting and Blood Clearance

Metallo-intercalators and metallo-insertors

Modular strategy for the construction of radiometalated antibodies for positron emission tomography based on inverse electron demand Diels-Alder click chemistry

Molecular Imaging of Ovarian Cancer

Near-Infrared Intraoperative Chemiluminescence Imaging

Noninvasive Interrogation of DLL3 Expression in Metastatic Small Cell Lung Cancer

On the consensus nomenclature rules for radiopharmaceutical chemistry - Reconsideration of radiochemical conversion

Optimization of a Pretargeted Strategy for the PET Imaging of Colorectal Carcinoma via the Modulation of Radioligand Pharmacokinetics.

PARP1-Targeted Radiotherapy in Mouse Models of Glioblastoma.

PET imaging with ⁸⁹Zr: from radiochemistry to the clinic

Poly(ADP-Ribose)Polymerase (PARP) Inhibitors and Radiation Therapy

Preclinical 89Zr Immuno-PET of High-Grade Serous Ovarian Cancer and Lymph Node Metastasis.

Pretargeted Imaging and Therapy

Pretargeted Immuno-PET of Pancreatic Cancer: Overcoming Circulating Antigen and Internalized Antibody to Reduce Radiation Doses

Pretargeted PET Imaging Using a Site-Specifically Labeled Immunoconjugate

Pretargeted Radioimmunotherapy Based on the Inverse Electron Demand Diels-Alder Reaction

Pretargeted radioimmunotherapy and SPECT imaging of peritoneal carcinomatosis using bioorthogonal click chemistry: probe selection and first proof-of-concept

Pretargeting of internalizing trastuzumab and cetuximab with a 18F-tetrazine tracer in xenograft models

Recognition of abasic sites and single base bulges in DNA by a metalloinsertor

Removal of Fc Glycans from [89Zr]Zr-DFO-anti-CD8 prevents peripheral depletion of CD8+ T cells

Role of metalation in the topoisomerase IIα inhibition and antiproliferation activity of a series of α-heterocyclic-N4-substituted thiosemicarbazones and their Cu(II) complexes.

Site-Specifically Labeled Antibody-Drug Conjugate for Simultaneous Therapy and ImmunoPET.

Site-Specifically Labeled Immunoconjugates for Molecular Imaging--Part 1: Cysteine Residues and Glycans

Site-Specifically Labeled Immunoconjugates for Molecular Imaging--Part 2: Peptide Tags and Unnatural Amino Acids

Site-specifically labeled CA19.9-targeted immunoconjugates for the PET, NIRF, and multimodal PET/NIRF imaging of pancreatic cancer.

Synthesis and Bioconjugation of Thiol-Reactive Reagents for the Creation of Site-Selectively Modified Immunoconjugates

Synthesis and evaluation of (18)F-labeled ATP competitive inhibitors of topoisomerase II as probes for imaging topoisomerase II expression.

Synthesis of the first radiolabeled 188Re N-heterocyclic carbene complex and initial studies on its potential use in radiopharmaceutical applications

Targeted brain tumor radiotherapy using an Auger emitter

Targeting Triple Negative Breast Cancer with a Nucleus-Directed p53 Tetramerization Domain Peptide

Targeting abasic sites and single base bulges in DNA with metalloinsertors

The Impact of FcγRI Binding on Immuno-PET

The Influence of Glycans-Specific Bioconjugation on the FcγRI Binding and In vivo Performance of 89Zr-DFO-Pertuzumab

The bioconjugation and radiosynthesis of 89Zr-DFO-labeled antibodies

The inverse electron demand Diels-Alder click reaction in radiochemistry

The synthesis and evaluation of N1-(4-(2-[18F]-fluoroethyl)phenyl)-N8-hydroxyoctanediamide ([18F]-FESAHA), a PET radiotracer designed for the delineation of histone deacetylase expression in cancer.

Thiol-Reactive Bifunctional Chelators for the Creation of Site-Selectively Modified Radioimmunoconjugates with Improved Stability.

Toward the Optimization of Click-Mediated Pretargeted Radioimmunotherapy

Underscoring the influence of inorganic chemistry on nuclear imaging with radiometals

Understanding the In Vivo Fate of Radioimmunoconjugates for PET and SPECT.

Unexpected oxidative C-C cleavage in the metallation of 2-substituted imidazolium salts to give N-heterocyclic carbene complexes.

What a difference a carbon makes: H₄octapa vs H₄C3octapa, ligands for In-111 and Lu-177 radiochemistry