Lista de obras -

A chemical probe that labels human pluripotent stem cells

artículo científico publicado en 2014

A β1-tubulin-based megakaryocyte maturation reporter system identifies novel drugs that promote platelet production

artículo científico publicado en 2018

Adipose Natural Regulatory B Cells Negatively Control Adipose Tissue Inflammation.

artículo científico publicado en 2013

Application of ex vivo flow chamber system for assessment of stent thrombosis

artículo científico publicado en 2002

Characterization of mesenchymal progenitor cells in the crown and root pulp of primary teeth.

artículo científico publicado en 2015

Congenital amegakaryocytic thrombocytopenia iPS cells exhibit defective MPL-mediated signaling

artículo científico publicado en 2013

Cytokine signaling, lipid raft clustering, and HSC hibernation

artículo científico publicado en 2007

Cytokine signals modulated via lipid rafts mimic niche signals and induce hibernation in hematopoietic stem cells

artículo científico publicado en 2006

De Novo Mutations Activating Germline TP53 in an Inherited Bone-Marrow-Failure Syndrome

publication published on 23 August 2018

Definitive proof for direct reprogramming of hematopoietic cells to pluripotency.

artículo científico publicado en 2009

Development of iPS cell-derived blood products and production guidelines

artículo científico publicado en 2017

Donor-dependent variations in hepatic differentiation from human-induced pluripotent stem cells

artículo científico publicado en 2012

Endomucin, a CD34-like sialomucin, marks hematopoietic stem cells throughout development

artículo científico publicado en 2005

Epigenetic traits inscribed in chromatin accessibility in aged hematopoietic stem cells

artículo científico publicado en 2022

Ex vivo generation of platelet products from human iPS cells

scientific article published on 01 December 2020

Expandable megakaryocyte cell lines enable clinically applicable generation of platelets from human induced pluripotent stem cells

artículo científico publicado en 2014

Functional significance of adenosine 5'-diphosphate receptor (P2Y(12)) in platelet activation initiated by binding of von Willebrand factor to platelet GP Ibalpha induced by conditions of high shear rate

artículo científico publicado en 2002

Generation and manipulation of human iPSC-derived platelets ⬇️

Generation of Col2a1-EGFP iPS cells for monitoring chondrogenic differentiation

artículo científico publicado en 2013

Generation of functional platelets from human embryonic stem cells in vitro via ES-sacs, VEGF-promoted structures that concentrate hematopoietic progenitors

scientific article published on 03 April 2008

Generation of induced pluripotent stem cells derived from primary and secondary myelofibrosis patient samples

artículo científico publicado en 2014

Generation of induced pluripotent stem cells from primary chronic myelogenous leukemia patient samples

artículo científico publicado en 2012

Genetic marking of hematopoietic stem and endothelial cells: identification of the Tmtsp gene encoding a novel cell surface protein with the thrombospondin-1 domain

scientific journal article

Growth and maturation of megakaryocytes is regulated by Lnk/Sh2b3 adaptor protein through crosstalk between cytokine- and integrin-mediated signals

artículo científico publicado en 2008

Heterozygous ITGA2B R995W mutation inducing constitutive activation of the αIIbβ3 receptor affects proplatelet formation and causes congenital macrothrombocytopenia

artículo científico publicado en 2011

Hyaline cartilage formation and tumorigenesis of implanted tissues derived from human induced pluripotent stem cells

artículo científico publicado en 2015

IL-1α induces thrombopoiesis through megakaryocyte rupture in response to acute platelet needs

artículo científico publicado en 2015

Immortalization of erythroblasts by c-MYC and BCL-XL enables large-scale erythrocyte production from human pluripotent stem cells

artículo científico publicado en 2013

In Vitro Generation of Megakaryocytes and Platelets from Human Embryonic Stem Cells and Induced Pluripotent Stem Cells ⬇️

artículo científico publicado el 1 de enero de 2012

In vivo imaging visualizes discoid platelet aggregations without endothelium disruption and implicates contribution of inflammatory cytokine and integrin signaling

artículo científico publicado en 2011

Integrin-αvβ3 regulates thrombopoietin-mediated maintenance of hematopoietic stem cells ⬇️

artículo científico publicado el 16 de noviembre de 2011

Linkage between the mechanisms of thrombocytopenia and thrombopoiesis

artículo científico publicado en 2016

Lnk negatively regulates self-renewal of hematopoietic stem cells by modifying thrombopoietin-mediated signal transduction

artículo científico publicado en 2007

Lnk regulates integrin alphaIIbbeta3 outside-in signaling in mouse platelets, leading to stabilization of thrombus development in vivo

artículo científico publicado en 2009

Metalloproteinase regulation improves in vitro generation of efficacious platelets from mouse embryonic stem cells

artículo científico publicado en 2008

Multicolor staining of globin subtypes reveals impaired globin switching during erythropoiesis in human pluripotent stem cells

artículo científico publicado en 2014

Nov/CCN3 regulates long-term repopulating activity of murine hematopoietic stem cells via integrin αvβ3

artículo científico publicado en 2014

Novel TPO receptor agonist TA-316 contributes to platelet biogenesis from human iPS cells

artículo científico publicado en 2017

PKA/CREB Signaling Triggers Initiation of Endothelial and Hematopoietic Cell Differentiation via Etv2 Induction ⬇️

artículo científico publicado el 1 de abril de 2012

Platelet biogenesis wears silkworm cocoons.

artículo científico publicado en 2015

Potential usefulness of human iPS cells on the generation of platelets

artículo científico publicado el 1 de diciembre de 2011

Reduction of N-glycolylneuraminic acid in human induced pluripotent stem cells generated or cultured under feeder- and serum-free defined conditions

artículo científico publicado en 2010

Relieving Dyrk1a repression of MKL1 confers an adult-like phenotype to human infantile megakaryocytes

artículo científico publicado en 2022

Selective Inhibition of ADAM17 Efficiently Mediates Glycoprotein Ibα Retention During Ex Vivo Generation of Human Induced Pluripotent Stem Cell-Derived Platelets

artículo científico publicado en 2016

Skewed megakaryopoiesis in human induced pluripotent stem cell-derived haematopoietic progenitor cells harbouring calreticulin mutations

artículo científico publicado en 2018

Spred1 Safeguards Hematopoietic Homeostasis against Diet-Induced Systemic Stress

artículo científico publicado en 2018

Stepwise development of hematopoietic stem cells from embryonic stem cells

artículo científico publicado en 2009

Suppressive effects of anagrelide on cell cycle progression and the maturation of megakaryocyte progenitor cell lines in human induced pluripotent stem cells

scientific article published on 05 September 2019

TGF-beta as a candidate bone marrow niche signal to induce hematopoietic stem cell hibernation

artículo científico publicado en 2008

TMEM16F is required for phosphatidylserine exposure and microparticle release in activated mouse platelets

artículo científico publicado en 2015

Ten years of induced pluripotency: from basic mechanisms to therapeutic applications

artículo científico publicado en 2016

The WAVE2/Abi1 complex differentially regulates megakaryocyte development and spreading: implications for platelet biogenesis and spreading machinery

scientific journal article

The actin polymerization regulator WAVE2 is required for early bone marrow repopulation by hematopoietic stem cells.

artículo científico publicado en 2009

The generation of induced pluripotent stem cells (iPSCs) from patients with infantile and late-onset types of Pompe disease and the effects of treatment with acid-α-glucosidase in Pompe's iPSCs

artículo científico publicado en 2014

Transient activation of c-MYC expression is critical for efficient platelet generation from human induced pluripotent stem cells

artículo científico publicado en 2010

Turbulence Activates Platelet Biogenesis to Enable Clinical Scale Ex Vivo Production

artículo científico publicado en 2018

Two differential flows in a bioreactor promoted platelet generation from human pluripotent stem cell–derived megakaryocytes ⬇️

artículo científico publicado el 22 de abril de 2013

Tyrosyl-tRNA synthetase stimulates thrombopoietin-independent hematopoiesis accelerating recovery from thrombocytopenia

article published in the Proceedings of the National Academy of Sciences of the United States of America

[Ex vivo platelet production from induced pluripotent stem cells]

artículo científico publicado en 2018

[Reconstitution of the hematopoietic system and clinical applications of iPS cells]

artículo científico publicado en 2019

iPSC-Derived Platelets Depleted of HLA Class I Are Inert to Anti-HLA Class I and Natural Killer Cell Immunity

artículo científico publicado en 2019

αIIbβ3 changes gears in MKs and platelets

scientific article published on 01 April 2019

Lista de obras de

A chemical probe that labels human pluripotent stem cells

A β1-tubulin-based megakaryocyte maturation reporter system identifies novel drugs that promote platelet production

Adipose Natural Regulatory B Cells Negatively Control Adipose Tissue Inflammation.

Application of ex vivo flow chamber system for assessment of stent thrombosis

Characterization of mesenchymal progenitor cells in the crown and root pulp of primary teeth.

Congenital amegakaryocytic thrombocytopenia iPS cells exhibit defective MPL-mediated signaling

Cytokine signaling, lipid raft clustering, and HSC hibernation

Cytokine signals modulated via lipid rafts mimic niche signals and induce hibernation in hematopoietic stem cells

De Novo Mutations Activating Germline TP53 in an Inherited Bone-Marrow-Failure Syndrome

Definitive proof for direct reprogramming of hematopoietic cells to pluripotency.

Development of iPS cell-derived blood products and production guidelines

Donor-dependent variations in hepatic differentiation from human-induced pluripotent stem cells

Endomucin, a CD34-like sialomucin, marks hematopoietic stem cells throughout development

Epigenetic traits inscribed in chromatin accessibility in aged hematopoietic stem cells

Ex vivo generation of platelet products from human iPS cells

Expandable megakaryocyte cell lines enable clinically applicable generation of platelets from human induced pluripotent stem cells

Functional significance of adenosine 5'-diphosphate receptor (P2Y(12)) in platelet activation initiated by binding of von Willebrand factor to platelet GP Ibalpha induced by conditions of high shear rate

Generation and manipulation of human iPSC-derived platelets ⬇️

Generation of Col2a1-EGFP iPS cells for monitoring chondrogenic differentiation

Generation of functional platelets from human embryonic stem cells in vitro via ES-sacs, VEGF-promoted structures that concentrate hematopoietic progenitors

Generation of induced pluripotent stem cells derived from primary and secondary myelofibrosis patient samples

Generation of induced pluripotent stem cells from primary chronic myelogenous leukemia patient samples

Genetic marking of hematopoietic stem and endothelial cells: identification of the Tmtsp gene encoding a novel cell surface protein with the thrombospondin-1 domain

Growth and maturation of megakaryocytes is regulated by Lnk/Sh2b3 adaptor protein through crosstalk between cytokine- and integrin-mediated signals

Heterozygous ITGA2B R995W mutation inducing constitutive activation of the αIIbβ3 receptor affects proplatelet formation and causes congenital macrothrombocytopenia

Hyaline cartilage formation and tumorigenesis of implanted tissues derived from human induced pluripotent stem cells

IL-1α induces thrombopoiesis through megakaryocyte rupture in response to acute platelet needs

Immortalization of erythroblasts by c-MYC and BCL-XL enables large-scale erythrocyte production from human pluripotent stem cells

In Vitro Generation of Megakaryocytes and Platelets from Human Embryonic Stem Cells and Induced Pluripotent Stem Cells ⬇️

In vivo imaging visualizes discoid platelet aggregations without endothelium disruption and implicates contribution of inflammatory cytokine and integrin signaling

Integrin-αvβ3 regulates thrombopoietin-mediated maintenance of hematopoietic stem cells ⬇️

Linkage between the mechanisms of thrombocytopenia and thrombopoiesis

Lnk negatively regulates self-renewal of hematopoietic stem cells by modifying thrombopoietin-mediated signal transduction

Lnk regulates integrin alphaIIbbeta3 outside-in signaling in mouse platelets, leading to stabilization of thrombus development in vivo

Metalloproteinase regulation improves in vitro generation of efficacious platelets from mouse embryonic stem cells

Multicolor staining of globin subtypes reveals impaired globin switching during erythropoiesis in human pluripotent stem cells

Nov/CCN3 regulates long-term repopulating activity of murine hematopoietic stem cells via integrin αvβ3

Novel TPO receptor agonist TA-316 contributes to platelet biogenesis from human iPS cells

PKA/CREB Signaling Triggers Initiation of Endothelial and Hematopoietic Cell Differentiation via Etv2 Induction ⬇️

Platelet biogenesis wears silkworm cocoons.

Potential usefulness of human iPS cells on the generation of platelets

Reduction of N-glycolylneuraminic acid in human induced pluripotent stem cells generated or cultured under feeder- and serum-free defined conditions

Relieving Dyrk1a repression of MKL1 confers an adult-like phenotype to human infantile megakaryocytes

Selective Inhibition of ADAM17 Efficiently Mediates Glycoprotein Ibα Retention During Ex Vivo Generation of Human Induced Pluripotent Stem Cell-Derived Platelets

Skewed megakaryopoiesis in human induced pluripotent stem cell-derived haematopoietic progenitor cells harbouring calreticulin mutations

Spred1 Safeguards Hematopoietic Homeostasis against Diet-Induced Systemic Stress

Stepwise development of hematopoietic stem cells from embryonic stem cells

Suppressive effects of anagrelide on cell cycle progression and the maturation of megakaryocyte progenitor cell lines in human induced pluripotent stem cells

TGF-beta as a candidate bone marrow niche signal to induce hematopoietic stem cell hibernation

TMEM16F is required for phosphatidylserine exposure and microparticle release in activated mouse platelets

Ten years of induced pluripotency: from basic mechanisms to therapeutic applications

The WAVE2/Abi1 complex differentially regulates megakaryocyte development and spreading: implications for platelet biogenesis and spreading machinery

The actin polymerization regulator WAVE2 is required for early bone marrow repopulation by hematopoietic stem cells.

The generation of induced pluripotent stem cells (iPSCs) from patients with infantile and late-onset types of Pompe disease and the effects of treatment with acid-α-glucosidase in Pompe's iPSCs

Transient activation of c-MYC expression is critical for efficient platelet generation from human induced pluripotent stem cells

Turbulence Activates Platelet Biogenesis to Enable Clinical Scale Ex Vivo Production

Two differential flows in a bioreactor promoted platelet generation from human pluripotent stem cell–derived megakaryocytes ⬇️

Tyrosyl-tRNA synthetase stimulates thrombopoietin-independent hematopoiesis accelerating recovery from thrombocytopenia

[Ex vivo platelet production from induced pluripotent stem cells]

[Reconstitution of the hematopoietic system and clinical applications of iPS cells]

iPSC-Derived Platelets Depleted of HLA Class I Are Inert to Anti-HLA Class I and Natural Killer Cell Immunity

αIIbβ3 changes gears in MKs and platelets