Lista de obras -

A human beta-cell line for transplantation therapy to control type 1 diabetes.

artículo científico publicado en 2005

A method to sequence and quantify DNA integration for monitoring outcome in gene therapy ⬇️

artículo científico publicado en 2011

A phase I/II clinical trial of beta-globin gene therapy for beta-thalassemia

artículo científico publicado en 2005

A reversibly immortalized human hepatocyte cell line as a source of hepatocyte-based biological support

artículo científico publicado en 2001

Activation and inhibition of the erythropoietin receptor by a membrane-anchored erythropoietin

artículo científico publicado en 2008

Advances in stem cell transplantation and gene therapy in the β-hemoglobinopathies.

artículo científico

Angiogenic synergism, vascular stability and improvement of hind-limb ischemia by a combination of PDGF-BB and FGF-2

artículo científico publicado en 2003

Arrayed lentiviral barcoding for quantification analysis of hematopoietic dynamics.

artículo científico publicado en 2013

Atypical BSE (BASE) transmitted from asymptomatic aging cattle to a primate

artículo científico publicado en 2008

BET bromodomain inhibition rescues erythropoietin differentiation of human erythroleukemia cell line UT7.

artículo científico publicado en 2012

Continuous intravascular secretion of endostatin in mice from transduced hematopoietic stem cells

artículo científico publicado en 2002

Controlled expansion of human endothelial cell populations by Cre-loxP-based reversible immortalization.

artículo científico publicado en 2002

Correction of murine β-thalassemia after minimal lentiviral gene transfer and homeostatic in vivo erythroid expansion

artículo científico publicado en 2011

Cre/loxP-Based Reversible Immortalization of Human Hepatocytes 1.

artículo científico publicado en 2001

Deficiency of the cytoskeletal protein SPECC1L leads to oblique facial clefting

artículo científico publicado en 2011

Design of a trans protease lentiviral packaging system that produces high titer virus

artículo científico publicado en 2007

Direct binding of pRb/E2F-2 to GATA-1 regulates maturation and terminal cell division during erythropoiesis

artículo científico publicado en 2009

Distribution of lentiviral vector integration sites in mice following therapeutic gene transfer to treat β-thalassemia

artículo científico publicado en 2011

Dynamics of gene-modified progenitor cells analyzed by tracking retroviral integration sites in a human SCID-X1 gene therapy trial

artículo científico publicado en 2010

Erythropoietin and IGF-1 signaling synchronize cell proliferation and maturation during erythropoiesis

artículo científico publicado en 2015

Establishment of a highly differentiated immortalized human cholangiocyte cell line with SV40T and hTERT.

artículo científico publicado en 2004

Establishment of an immortalized human-liver endothelial cell line with SV40T and hTERT.

artículo científico publicado en 2004

Establishment of immortalized human hepatic stellate scavenger cells to develop bioartificial livers.

artículo científico publicado en 2003

Expression of a human beta-globin transgene in erythroid cells derived from retrovirally transduced transplantable human fetal liver and cord blood cells

artículo científico publicado en 2002

Expression of an anti-sickling beta-globin in human erythroblasts derived from retrovirally transduced primitive normal and sickle cell disease hematopoietic cells

artículo científico publicado en 2004

Gene Therapy in Patients with Transfusion-Dependent β-Thalassemia

article

Gene Therapy in a Patient with Sickle Cell Disease

artículo científico publicado en 2017

Gene Therapy in a Patient with Sickle Cell Disease

artículo científico publicado en 2017

Gene Therapy of the β-Hemoglobinopathies by Lentiviral Transfer of the β(A(T87Q))-Globin Gene

artículo científico publicado en 2016

Gene therapy: primed for take-off

artículo científico publicado en 2013

Glycoprotein 170 induces platelet-activating factor receptor membrane expression and confers tumor cell hypersensitivity to NK-dependent cell lysis

artículo científico publicado en 2004

HSP70 sequestration by free α-globin promotes ineffective erythropoiesis in β-thalassaemia

artículo científico publicado en 2014

Hematopoietic stem cell gene therapy with a lentiviral vector in X-linked adrenoleukodystrophy

artículo científico publicado en 2009

Hemoglobin disorders: lentiviral gene therapy in the starting blocks to enter clinical practice

article

High-level beta-globin expression and preferred intragenic integration after lentiviral transduction of human cord blood stem cells

artículo científico publicado en 2004

Highly efficient in vitro and in vivo delivery of functional RNAs using new versatile MS2-chimeric retrovirus-like particles.

artículo científico publicado en 2015

Immortalization of a primate bipotent epithelial liver stem cell

artículo científico publicado en 2002

Immortalization of bone marrow-derived human mesenchymal stem cells by removable simian virus 40T antigen gene: analysis of the ability to support expansion of cord blood hematopoietic progenitor cells.

artículo científico publicado en 2003

In vivo gene delivery to synovium by lentiviral vectors.

artículo científico publicado en 2002

Induced pluripotent stem cell generation from a man carrying a complex chromosomal rearrangement as a genetic model for infertility studies

artículo científico publicado en 2017

Inhaled nitric oxide protects transgenic SAD mice from sickle cell disease-specific lung injury induced by hypoxia/reoxygenation

artículo científico publicado en 2003

Inhibition of the acetyl lysine-binding pocket of bromodomain and extraterminal domain proteins interferes with adipogenesis

artículo científico publicado en 2016

Is normal hematopoiesis maintained solely by long-term multipotent stem cells?

artículo científico publicado en 2011

Lentiviral-mediated gene delivery to synovium: potent intra-articular expression with amplification by inflammation ⬇️

artículo científico publicado el 1 de abril de 2003

Lentivirus vectors in β-thalassemia.

artículo científico publicado en 2012

Parallel assessment of globin lentiviral transfer in induced pluripotent stem cells and adult hematopoietic stem cells derived from the same transplanted β-thalassemia patient

artículo científico publicado en 2013

Permanent and panerythroid correction of murine beta thalassemia by multiple lentiviral integration in hematopoietic stem cells

artículo científico publicado en 2002

Phenotypic and functional changes induced in hematopoietic stem/progenitor cells after gamma-ray radiation exposure

artículo científico publicado en 2009

Phosphatidylinositol 3-kinase/Akt induced by erythropoietin renders the erythroid differentiation factor GATA-1 competent for TIMP-1 gene transactivation.

artículo científico publicado en 2005

Pioglitazone together with imatinib in chronic myeloid leukemia: A proof of concept study

artículo científico publicado en 2016

Placenta growth factor-1 antagonizes VEGF-induced angiogenesis and tumor growth by the formation of functionally inactive PlGF-1/VEGF heterodimers

artículo científico publicado en 2002

Postnatal neovascularization by endothelial progenitor cells immortalized with the simian virus 40T antigen gene.

artículo científico publicado en 2006

Preclinical evaluation of efficacy and safety of an improved lentiviral vector for the treatment of β-thalassemia and sickle cell disease

artículo científico publicado en 2015

Prevention of murine erythropoietic protoporphyria-associated skin photosensitivity and liver disease by dermal and hepatic ferrochelatase

artículo científico publicado en 2005

Repopulation of athymic mouse liver by cryopreserved early human fetal hepatoblasts

artículo científico publicado en 2004

Role of bone marrow cell trafficking in replenishing skeletal muscle SP and MP cell populations

artículo científico publicado en 2004

Stem cell factor-displaying simian immunodeficiency viral vectors together with a low conditioning regimen allow for long-term engraftment of gene-marked autologous hematopoietic stem cells in macaques.

artículo científico publicado en 2012

Successful Retroviral Gene Transfer of Simian Virus 40 T Antigen and Herpes Simplex Virus-Thymidine Kinase into Human Hepatocytes 1.

artículo científico publicado en 2001

Survival of liver failure pigs by transplantation of reversibly immortalized human hepatocytes with Tamoxifen-mediated self-recombination

artículo científico publicado en 2007

Tolerance by selective in vivo expansion of foreign major histocompatibility complex-transduced autologous bone marrow

artículo científico publicado en 2005

Transfusion independence and HMGA2 activation after gene therapy of human β-thalassaemia

artículo científico publicado en 2010

Transplantation of reversibly immortalized insulin-secreting human hepatocytes controls diabetes in pancreatectomized pigs

artículo científico publicado en 2004

Treatment of liver failure in rats with end-stage cirrhosis by transplantation of immortalized hepatocytes

artículo científico publicado en 2002

UM171 Enhances Lentiviral Gene Transfer and Recovery of Primitive Human Hematopoietic Cells

article

Unfulfilled promise of endostatin in a gene therapy-xenotransplant model of human acute lymphocytic leukemia

artículo científico publicado en 2002

eGFP reporter genes silence LCRbeta-globin transgene expression via CpG dinucleotides

artículo científico publicado en 2005

Lista de obras de

A human beta-cell line for transplantation therapy to control type 1 diabetes.

A method to sequence and quantify DNA integration for monitoring outcome in gene therapy ⬇️

A phase I/II clinical trial of beta-globin gene therapy for beta-thalassemia

A reversibly immortalized human hepatocyte cell line as a source of hepatocyte-based biological support

Activation and inhibition of the erythropoietin receptor by a membrane-anchored erythropoietin

Advances in stem cell transplantation and gene therapy in the β-hemoglobinopathies.

Angiogenic synergism, vascular stability and improvement of hind-limb ischemia by a combination of PDGF-BB and FGF-2

Arrayed lentiviral barcoding for quantification analysis of hematopoietic dynamics.

Atypical BSE (BASE) transmitted from asymptomatic aging cattle to a primate

BET bromodomain inhibition rescues erythropoietin differentiation of human erythroleukemia cell line UT7.

Continuous intravascular secretion of endostatin in mice from transduced hematopoietic stem cells

Controlled expansion of human endothelial cell populations by Cre-loxP-based reversible immortalization.

Correction of murine β-thalassemia after minimal lentiviral gene transfer and homeostatic in vivo erythroid expansion

Cre/loxP-Based Reversible Immortalization of Human Hepatocytes 1.

Deficiency of the cytoskeletal protein SPECC1L leads to oblique facial clefting

Design of a trans protease lentiviral packaging system that produces high titer virus

Direct binding of pRb/E2F-2 to GATA-1 regulates maturation and terminal cell division during erythropoiesis

Distribution of lentiviral vector integration sites in mice following therapeutic gene transfer to treat β-thalassemia

Dynamics of gene-modified progenitor cells analyzed by tracking retroviral integration sites in a human SCID-X1 gene therapy trial

Erythropoietin and IGF-1 signaling synchronize cell proliferation and maturation during erythropoiesis

Establishment of a highly differentiated immortalized human cholangiocyte cell line with SV40T and hTERT.

Establishment of an immortalized human-liver endothelial cell line with SV40T and hTERT.

Establishment of immortalized human hepatic stellate scavenger cells to develop bioartificial livers.

Expression of a human beta-globin transgene in erythroid cells derived from retrovirally transduced transplantable human fetal liver and cord blood cells

Expression of an anti-sickling beta-globin in human erythroblasts derived from retrovirally transduced primitive normal and sickle cell disease hematopoietic cells

Gene Therapy in Patients with Transfusion-Dependent β-Thalassemia

Gene Therapy in a Patient with Sickle Cell Disease

Gene Therapy in a Patient with Sickle Cell Disease

Gene Therapy of the β-Hemoglobinopathies by Lentiviral Transfer of the β(A(T87Q))-Globin Gene

Gene therapy: primed for take-off

Glycoprotein 170 induces platelet-activating factor receptor membrane expression and confers tumor cell hypersensitivity to NK-dependent cell lysis

HSP70 sequestration by free α-globin promotes ineffective erythropoiesis in β-thalassaemia

Hematopoietic stem cell gene therapy with a lentiviral vector in X-linked adrenoleukodystrophy

Hemoglobin disorders: lentiviral gene therapy in the starting blocks to enter clinical practice

High-level beta-globin expression and preferred intragenic integration after lentiviral transduction of human cord blood stem cells

Highly efficient in vitro and in vivo delivery of functional RNAs using new versatile MS2-chimeric retrovirus-like particles.

Immortalization of a primate bipotent epithelial liver stem cell

Immortalization of bone marrow-derived human mesenchymal stem cells by removable simian virus 40T antigen gene: analysis of the ability to support expansion of cord blood hematopoietic progenitor cells.

In vivo gene delivery to synovium by lentiviral vectors.

Induced pluripotent stem cell generation from a man carrying a complex chromosomal rearrangement as a genetic model for infertility studies

Inhaled nitric oxide protects transgenic SAD mice from sickle cell disease-specific lung injury induced by hypoxia/reoxygenation

Inhibition of the acetyl lysine-binding pocket of bromodomain and extraterminal domain proteins interferes with adipogenesis

Is normal hematopoiesis maintained solely by long-term multipotent stem cells?

Lentiviral-mediated gene delivery to synovium: potent intra-articular expression with amplification by inflammation ⬇️

Lentivirus vectors in β-thalassemia.

Parallel assessment of globin lentiviral transfer in induced pluripotent stem cells and adult hematopoietic stem cells derived from the same transplanted β-thalassemia patient

Permanent and panerythroid correction of murine beta thalassemia by multiple lentiviral integration in hematopoietic stem cells

Phenotypic and functional changes induced in hematopoietic stem/progenitor cells after gamma-ray radiation exposure

Phosphatidylinositol 3-kinase/Akt induced by erythropoietin renders the erythroid differentiation factor GATA-1 competent for TIMP-1 gene transactivation.

Pioglitazone together with imatinib in chronic myeloid leukemia: A proof of concept study

Placenta growth factor-1 antagonizes VEGF-induced angiogenesis and tumor growth by the formation of functionally inactive PlGF-1/VEGF heterodimers

Postnatal neovascularization by endothelial progenitor cells immortalized with the simian virus 40T antigen gene.

Preclinical evaluation of efficacy and safety of an improved lentiviral vector for the treatment of β-thalassemia and sickle cell disease

Prevention of murine erythropoietic protoporphyria-associated skin photosensitivity and liver disease by dermal and hepatic ferrochelatase

Repopulation of athymic mouse liver by cryopreserved early human fetal hepatoblasts

Role of bone marrow cell trafficking in replenishing skeletal muscle SP and MP cell populations

Stem cell factor-displaying simian immunodeficiency viral vectors together with a low conditioning regimen allow for long-term engraftment of gene-marked autologous hematopoietic stem cells in macaques.

Successful Retroviral Gene Transfer of Simian Virus 40 T Antigen and Herpes Simplex Virus-Thymidine Kinase into Human Hepatocytes 1.

Survival of liver failure pigs by transplantation of reversibly immortalized human hepatocytes with Tamoxifen-mediated self-recombination

Tolerance by selective in vivo expansion of foreign major histocompatibility complex-transduced autologous bone marrow

Transfusion independence and HMGA2 activation after gene therapy of human β-thalassaemia

Transplantation of reversibly immortalized insulin-secreting human hepatocytes controls diabetes in pancreatectomized pigs

Treatment of liver failure in rats with end-stage cirrhosis by transplantation of immortalized hepatocytes

UM171 Enhances Lentiviral Gene Transfer and Recovery of Primitive Human Hematopoietic Cells

Unfulfilled promise of endostatin in a gene therapy-xenotransplant model of human acute lymphocytic leukemia

eGFP reporter genes silence LCRbeta-globin transgene expression via CpG dinucleotides