Lista de obras -

A phenome-wide association study of a lipoprotein-associated phospholipase A2 loss-of-function variant in 90 000 Chinese adults

artículo científico publicado en 2016

A statin-dependent QTL for GATM expression is associated with statin-induced myopathy

artículo científico publicado en 2013

Adiposity and risk of ischaemic and haemorrhagic stroke in 0·5 million Chinese men and women: a prospective cohort study.

artículo científico publicado en 2018

Assessment of Vascular Event Prevention and Cognitive Function Among Older Adults With Preexisting Vascular Disease or Diabetes: A Secondary Analysis of 3 Randomized Clinical Trials

scholarly article published 1 March 2019

Association of vitamin D with risk of type 2 diabetes: A Mendelian randomisation study in European and Chinese adults.

artículo científico publicado en 2018

Biomarkers of inflammation predict both vascular and non-vascular mortality in older men.

artículo científico publicado en 2008

C-reactive protein concentration and the vascular benefits of statin therapy: an analysis of 20 536 patients in the Heart Protection Study ⬇️

artículo científico publicado el 27 de enero de 2011

C-reactive protein in the Heart Protection Study – Authors' reply

artículo científico publicado en 2011

Cholesterol fractions and apolipoproteins as risk factors for heart disease mortality in older men.

artículo científico publicado en 2007

Common variants at 30 loci contribute to polygenic dyslipidemia

artículo científico publicado en 2009

Conventional and genetic evidence on alcohol and vascular disease aetiology: a prospective study of 500 000 men and women in China

article

Cost-effectiveness of simvastatin in people at different levels of vascular disease risk: economic analysis of a randomised trial in 20,536 individuals

artículo científico publicado en 2005

Effect of temperature and light on the stability of fat-soluble vitamins in whole blood over several days: implications for epidemiological studies

artículo científico publicado en 2004

Effects of Vascular and Nonvascular Adverse Events and of Extended-Release Niacin With Laropiprant on Health and Healthcare Costs

artículo científico

Effects of cholesterol-lowering with simvastatin on stroke and other major vascular events in 20536 people with cerebrovascular disease or other high-risk conditions

artículo científico publicado en 2004

Effects of extended-release niacin with laropiprant in high-risk patients

artículo científico publicado en 2014

Effects of homocysteine lowering with B vitamins on cognitive aging: meta-analysis of 11 trials with cognitive data on 22,000 individuals

artículo científico publicado en 2014

Effects of homocysteine-lowering with folic acid plus vitamin B12 vs placebo on mortality and major morbidity in myocardial infarction survivors: a randomized trial

artículo científico publicado en 2010

Effects of simvastatin 40 mg daily on muscle and liver adverse effects in a 5-year randomized placebo-controlled trial in 20,536 high-risk people

artículo científico publicado en 2009

Efficacy and safety of statin therapy in older people: a meta-analysis of individual participant data from 28 randomised controlled trials

artículo científico publicado en 2019

Fibrinogen and coronary heart disease: test of causality by 'Mendelian randomization'

artículo científico publicado en 2006

Genetic variants associated with Lp(a) lipoprotein level and coronary disease

artículo científico publicado en 2009

Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes

artículo científico publicado en 2011

Homocysteine and Coronary Heart Disease: Meta-analysis of MTHFR Case-Control Studies, Avoiding Publication Bias ⬇️

artículo científico publicado el 21 de febrero de 2012

Impact of common genetic variation on response to simvastatin therapy among 18 705 participants in the Heart Protection Study

artículo científico publicado en 2012

Intensive lowering of LDL cholesterol with 80 mg versus 20 mg simvastatin daily in 12 064 survivors of myocardial infarction: a double-blind randomised trial ⬇️

artículo científico publicado el 8 de noviembre de 2010

Large-scale association analysis identifies new risk loci for coronary artery disease

artículo científico publicado en 2012

Large-scale evidence that the cardiotoxicity of smoking is not significantly modified by the apolipoprotein E epsilon2/epsilon3/epsilon4 genotype

artículo científico publicado en 2003

Lifetime cost effectiveness of simvastatin in a range of risk groups and age groups derived from a randomised trial of 20,536 people

artículo científico publicado en 2006

Lipid-related genes and myocardial infarction in 4685 cases and 3460 controls: discrepancies between genotype, blood lipid concentrations, and coronary disease risk

scientific article published on 15 July 2004

Lipids and Lipoproteins and Risk of Different Vascular Events in the MRC/BHF Heart Protection Study ⬇️

artículo científico publicado el 26 de abril de 2012

Lipoprotein(a) genetic variants associated with coronary and peripheral vascular disease but not with stroke risk in the Heart Protection Study

artículo científico

Lipoprotein-Associated Phospholipase A2 Loss-of-Function Variant and Risk of Vascular Diseases in 90,000 Chinese Adults

artículo científico publicado en 2016

Lymphotoxin-alpha gene and risk of myocardial infarction in 6,928 cases and 2,712 controls in the ISIS case-control study

artículo científico publicado en 2006

MRC/BHF Heart Protection Study of cholesterol-lowering with simvastatin in 5963 people with diabetes: a randomised placebo-controlled trial

artículo científico publicado en 2003

N-terminal Pro-B-type natriuretic peptide, vascular disease risk, and cholesterol reduction among 20,536 patients in the MRC/BHF heart protection study

artículo científico publicado en 2007

Newly identified loci that influence lipid concentrations and risk of coronary artery disease

artículo científico publicado en 2008

No impact of KIF6 genotype on vascular risk and statin response among 18,348 randomized patients in the heart protection study

artículo científico publicado en 2011

Reply to Garrard and Jacoby and Smith et al

artículo científico publicado en 2015

Risk prediction for cardiovascular disease using ECG data in the China kadoorie biobank

artículo científico publicado en 2016

Stability of plasma analytes after delayed separation of whole blood: implications for epidemiological studies

artículo científico publicado en 2003

The effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): a randomised placebo-controlled trial

artículo científico publicado en 2011

The exon 1–8C/G SNP in the PSMA6 gene contributes only a small amount to the burden of myocardial infarction in 6946 cases and 2720 controls from a United Kingdom population

article

The joint effects of apolipoprotein B, apolipoprotein A1, LDL cholesterol, and HDL cholesterol on risk: 3510 cases of acute myocardial infarction and 9805 controls

scientific article published on 11 June 2009

Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation

artículo científico publicado en 2015

Lista de obras de

A phenome-wide association study of a lipoprotein-associated phospholipase A2 loss-of-function variant in 90 000 Chinese adults

A statin-dependent QTL for GATM expression is associated with statin-induced myopathy

Adiposity and risk of ischaemic and haemorrhagic stroke in 0·5 million Chinese men and women: a prospective cohort study.

Assessment of Vascular Event Prevention and Cognitive Function Among Older Adults With Preexisting Vascular Disease or Diabetes: A Secondary Analysis of 3 Randomized Clinical Trials

Association of vitamin D with risk of type 2 diabetes: A Mendelian randomisation study in European and Chinese adults.

Biomarkers of inflammation predict both vascular and non-vascular mortality in older men.

C-reactive protein concentration and the vascular benefits of statin therapy: an analysis of 20 536 patients in the Heart Protection Study ⬇️

C-reactive protein in the Heart Protection Study – Authors' reply

Cholesterol fractions and apolipoproteins as risk factors for heart disease mortality in older men.

Common variants at 30 loci contribute to polygenic dyslipidemia

Conventional and genetic evidence on alcohol and vascular disease aetiology: a prospective study of 500 000 men and women in China

Cost-effectiveness of simvastatin in people at different levels of vascular disease risk: economic analysis of a randomised trial in 20,536 individuals

Effect of temperature and light on the stability of fat-soluble vitamins in whole blood over several days: implications for epidemiological studies

Effects of Vascular and Nonvascular Adverse Events and of Extended-Release Niacin With Laropiprant on Health and Healthcare Costs

Effects of cholesterol-lowering with simvastatin on stroke and other major vascular events in 20536 people with cerebrovascular disease or other high-risk conditions

Effects of extended-release niacin with laropiprant in high-risk patients

Effects of homocysteine lowering with B vitamins on cognitive aging: meta-analysis of 11 trials with cognitive data on 22,000 individuals

Effects of homocysteine-lowering with folic acid plus vitamin B12 vs placebo on mortality and major morbidity in myocardial infarction survivors: a randomized trial

Effects of simvastatin 40 mg daily on muscle and liver adverse effects in a 5-year randomized placebo-controlled trial in 20,536 high-risk people

Efficacy and safety of statin therapy in older people: a meta-analysis of individual participant data from 28 randomised controlled trials

Fibrinogen and coronary heart disease: test of causality by 'Mendelian randomization'

Genetic variants associated with Lp(a) lipoprotein level and coronary disease

Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes

Homocysteine and Coronary Heart Disease: Meta-analysis of MTHFR Case-Control Studies, Avoiding Publication Bias ⬇️

Impact of common genetic variation on response to simvastatin therapy among 18 705 participants in the Heart Protection Study

Intensive lowering of LDL cholesterol with 80 mg versus 20 mg simvastatin daily in 12 064 survivors of myocardial infarction: a double-blind randomised trial ⬇️

Large-scale association analysis identifies new risk loci for coronary artery disease

Large-scale evidence that the cardiotoxicity of smoking is not significantly modified by the apolipoprotein E epsilon2/epsilon3/epsilon4 genotype

Lifetime cost effectiveness of simvastatin in a range of risk groups and age groups derived from a randomised trial of 20,536 people

Lipid-related genes and myocardial infarction in 4685 cases and 3460 controls: discrepancies between genotype, blood lipid concentrations, and coronary disease risk

Lipids and Lipoproteins and Risk of Different Vascular Events in the MRC/BHF Heart Protection Study ⬇️

Lipoprotein(a) genetic variants associated with coronary and peripheral vascular disease but not with stroke risk in the Heart Protection Study

Lipoprotein-Associated Phospholipase A2 Loss-of-Function Variant and Risk of Vascular Diseases in 90,000 Chinese Adults

Lymphotoxin-alpha gene and risk of myocardial infarction in 6,928 cases and 2,712 controls in the ISIS case-control study

MRC/BHF Heart Protection Study of cholesterol-lowering with simvastatin in 5963 people with diabetes: a randomised placebo-controlled trial

N-terminal Pro-B-type natriuretic peptide, vascular disease risk, and cholesterol reduction among 20,536 patients in the MRC/BHF heart protection study

Newly identified loci that influence lipid concentrations and risk of coronary artery disease

No impact of KIF6 genotype on vascular risk and statin response among 18,348 randomized patients in the heart protection study

Reply to Garrard and Jacoby and Smith et al

Risk prediction for cardiovascular disease using ECG data in the China kadoorie biobank

Stability of plasma analytes after delayed separation of whole blood: implications for epidemiological studies

The effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): a randomised placebo-controlled trial

The exon 1–8C/G SNP in the PSMA6 gene contributes only a small amount to the burden of myocardial infarction in 6946 cases and 2720 controls from a United Kingdom population

The joint effects of apolipoprotein B, apolipoprotein A1, LDL cholesterol, and HDL cholesterol on risk: 3510 cases of acute myocardial infarction and 9805 controls

Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation