Lista de obras -

Congenic expression of poly-GA but not poly-PR in mice triggers selective neuron loss and interferon responses found in C9orf72 ALS

scientific article published on 19 June 2020

Control of gene editing by manipulation of DNA repair mechanisms

artículo científico publicado en 2017

Creation of targeted genomic deletions using TALEN or CRISPR/Cas nuclease pairs in one-cell mouse embryos.

artículo científico publicado en 2014

Direct production of mouse disease models by embryo microinjection of TALENs and oligodeoxynucleotides

artículo científico publicado en 2013

Gene Editing in One-Cell Embryos by Zinc-Finger and TAL Nucleases.

artículo científico publicado en 2012

Gene editing in mouse zygotes using the CRISPR/Cas9 system

artículo científico publicado en 2017

Generating conditional knockout mice

artículo científico publicado en 2011

Generation of targeted mouse mutants by embryo microinjection of TALEN mRNA.

artículo científico

Generation of targeted mouse mutants by embryo microinjection of TALENs

artículo científico publicado en 2014

Genome Editing in Mice Using TALE Nucleases

artículo científico publicado en 2016

Highly efficient targeted mutagenesis in mice using TALENs

artículo científico publicado en 2013

Increasing the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells.

artículo científico publicado en 2015

Local knockdown of ERK2 in the adult mouse brain via adeno-associated virus-mediated RNA interference.

scientific article published on 04 December 2008

MAPK signaling determines anxiety in the juvenile mouse brain but depression-like behavior in adults

artículo científico publicado en 2012

Rational correction of pathogenic conformational defects in HTRA1

artículo científico publicado en 2024

The FTD-like syndrome causing TREM2 T66M mutation impairs microglia function, brain perfusion, and glucose metabolism.

artículo científico publicado en 2017

The Trem2 R47H Alzheimer's risk variant impairs splicing and reduces Trem2 mRNA and protein in mice but not in humans

scholarly article by Xianyuan Xiang published in September 2018

Lista de obras de

Congenic expression of poly-GA but not poly-PR in mice triggers selective neuron loss and interferon responses found in C9orf72 ALS

Control of gene editing by manipulation of DNA repair mechanisms

Creation of targeted genomic deletions using TALEN or CRISPR/Cas nuclease pairs in one-cell mouse embryos.

Direct production of mouse disease models by embryo microinjection of TALENs and oligodeoxynucleotides

Gene Editing in One-Cell Embryos by Zinc-Finger and TAL Nucleases.

Gene editing in mouse zygotes using the CRISPR/Cas9 system

Generating conditional knockout mice

Generation of targeted mouse mutants by embryo microinjection of TALEN mRNA.

Generation of targeted mouse mutants by embryo microinjection of TALENs

Genome Editing in Mice Using TALE Nucleases

Highly efficient targeted mutagenesis in mice using TALENs

Increasing the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells.

Local knockdown of ERK2 in the adult mouse brain via adeno-associated virus-mediated RNA interference.

MAPK signaling determines anxiety in the juvenile mouse brain but depression-like behavior in adults

Rational correction of pathogenic conformational defects in HTRA1

The FTD-like syndrome causing TREM2 T66M mutation impairs microglia function, brain perfusion, and glucose metabolism.

The Trem2 R47H Alzheimer's risk variant impairs splicing and reduces Trem2 mRNA and protein in mice but not in humans