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* Hypoxia for Mesenchymal Stem Cell Expansion and Differentiation: The Best Way for Enhancing TGFß-Induced Chondrogenesis and Preventing Calcifications in Alginate Beads

artículo científico publicado en 2017

A simple two dimensional culture method to study the hypertrophic differentiation of rat articular chondrocytes.

artículo científico publicado en 2015

Angelica Sinensis polysaccharides stimulated UDP-sugar synthase genes through promoting gene expression of IGF-1 and IGF1R in chondrocytes: promoting anti-osteoarthritic activity

artículo científico publicado en 2014

Angelica sinensis and osteoarthritis: a natural therapeutic link?

artículo científico

Assessment of catechol induction and glucuronidation in rat liver microsomes

artículo científico publicado en 2004

Autoantibodies directed against the UDP-glucuronosyltransferases in human autoimmune hepatitis

artículo científico publicado en 2004

Biochemical and thermodynamic characterization of mutated β1,4-galactosyltransferase 7 involved in the progeroid form of the Ehlers–Danlos syndrome

artículo científico publicado el 1 de diciembre de 2010

Biomechanical and biochemical protective effect of low-level laser therapy for Achilles tendinitis.

artículo científico publicado en 2013

C-propeptides of procollagens I alpha 1 and II that differentially accumulate in enchondromas versus chondrosarcomas regulate tumor cell survival and migration

artículo científico publicado en 2010

CYP 2C19 and UDP-glucuronosyltransferases not only for drugs but also for endobiotics

artículo científico publicado en 2014

Caffeine-induced activated glucocorticoid metabolism in the hippocampus causes hypothalamic-pituitary-adrenal axis inhibition in fetal rats.

artículo científico publicado en 2012

Caffeine-induced fetal rat over-exposure to maternal glucocorticoid and histone methylation of liver IGF-1 might cause skeletal growth retardation

scientific journal article

Carboxyl nonsteroidal anti-inflammatory drugs are efficiently glucuronidated by microsomes of the human gastrointestinal tract.

artículo científico publicado en 2004

Characterization of catechol glucuronidation in rat liver

artículo científico publicado en 2002

Chondrocalcin is internalized by chondrocytes and triggers cartilage destruction via an interleukin-1β-dependent pathway

artículo científico publicado en 2013

Chondroitin sulfate N-acetylgalactosaminyltransferase-1 (CSGalNAcT-1) involved in chondroitin sulfate initiation: Impact of sulfation on activity and specificity.

artículo científico publicado en 2011

Comparison of electrospray, atmospheric pressure chemical ionization, and atmospheric pressure photoionization in the identification of apomorphine, dobutamine, and entacapone phase II metabolites in biological samples

artículo científico publicado en 2002

Correction: TNF/TNFR signal transduction pathway-mediated anti-apoptosis and anti-inflammatory effects of sodium ferulate on IL-1β- induced rat osteoarthritis chondrocytes in vitro

artículo científico publicado en 2013

Covalent attachment of epoxide hydrolase to dextran

Cucurbitacins from Ecballium elaterium juice increase the binding of bilirubin and ibuprofen to albumin in human plasma

artículo científico publicado en 2007

Cytotoxic effects of the quinolone levofloxacin on rabbit meniscus cells

artículo científico publicado en 2013

Differential induction profile of drug-metabolizing enzymes after treatment with hypolipidaemic agents

Effect of Angelica sinensis Polysaccharides on Osteoarthritis In Vivo and In Vitro: A Possible Mechanism to Promote Proteoglycans Synthesis

artículo científico publicado en 2013

Effect of nicotine on chondrogenic differentiation of rat bone marrow mesenchymal stem cells in alginate bead culture

artículo científico publicado en 2012

Effect of nicotine on the proliferation and chondrogenic differentiation of the human Wharton's jelly mesenchymal stem cells

artículo científico publicado en 2017

Effects and Interactions of Prenatal Ethanol Exposure, a Post-Weaning High-Fat Diet and Gender on Adult Hypercholesterolemia Occurrence in Offspring Rats

artículo científico publicado en 2017

Effects of adenovirus-mediated bFGF, IL-1Ra and IGF-1 gene transfer on human osteoarthritic chondrocytes and osteoarthritis in rabbits

artículo científico publicado el 31 de octubre de 2010

Establishment of a reliable method for direct proteome characterization of human articular cartilage

scientific article published on 09 May 2006

Evidence of calcium-dependent pathway in the regulation of human beta1,3-glucuronosyltransferase-1 (GlcAT-I) gene expression: a key enzyme in proteoglycan synthesis

artículo científico publicado en 2006

Fetal rat metabonome alteration by prenatal caffeine ingestion probably due to the increased circulatory glucocorticoid level and altered peripheral glucose and lipid metabolic pathways

artículo científico publicado en 2012

Gender-specific increase in susceptibility to metabolic syndrome of offspring rats after prenatal caffeine exposure with post-weaning high-fat diet

artículo científico publicado en 2015

Glucuronidation of catechols by human hepatic, gastric, and intestinal microsomal UDP-glucuronosyltransferases (UGT) and recombinant UGT1A6, UGT1A9, and UGT2B7

scientific article published on 01 March 2003

Glucuronidation of odorant molecules in the rat olfactory system: activity, expression and age-linked modifications of UDP-glucuronosyltransferase isoforms, UGT1A6 and UGT2A1, and relation to mitral cell activity

artículo científico publicado en 2002

Identification of aspartic acid and histidine residues mediating the reaction mechanism and the substrate specificity of the human UDP-glucuronosyltransferases 1A.

artículo científico publicado en 2007

Identification of the Human UDP-glucuronosyltransferase Isoforms Involved in the Glucuronidation of the Phytochemical Ferulic Acid

artículo científico publicado el 14 de marzo de 2011

Immobilization of epoxide hydrolase purified from rat liver microsomes

In malignant cartilagenous tumors, immunohistochemical expression of procollagen PC1CP peptide is higher and that of PC2CP lower than in benign cartilaginous lesions

artículo científico publicado en 2015

In vitro evaluation of glucuronidation of monohydroxylated aglycones related to quantum chemically-calculated parameters

In vitro stereoselective covalent binding of carprofen glucuronides to human serum albumin: characterization of the mechanism

artículo científico publicado el 1 de enero de 2003

Increased expression of matrilin-3 not only in osteoarthritic articular cartilage but also in cartilage-forming tumors, and down-regulation of SOX9 via epidermal growth factor domain 1-dependent signaling.

artículo científico publicado en 2008

Increased susceptibility of prenatal food restricted offspring to high-fat diet-induced nonalcoholic fatty liver disease is intrauterine programmed

artículo científico publicado en 2016

Influencing factors, underlying mechanism and interactions affecting hypercholesterolemia in adult offspring with caffeine exposure during pregnancy.

artículo científico publicado en 2018

Insights on membrane topology and structure/function of UDP-glucuronosyltransferases

artículo científico publicado en 2010

Interaction of cucurbitacins with human serum albumin: Thermodynamic characteristics and influence on the binding of site specific ligands

artículo científico publicado en 2009

Intrauterine programming of Glucocorticoid-Insulin-Like Growth Factor 1 axis-mediated developmental origin of osteoporosis susceptibility in female offspring rats of prenatal caffeine exposure

artículo científico publicado en 2018

Label-free relative quantification applied to LC-MALDI acquisition for rapid analysis of chondrocyte secretion modulation.

artículo científico publicado en 2014

Low-level laser therapy in collagenase-induced Achilles tendinitis in rats: analyses of biochemical and biomechanical aspects

artículo científico publicado en 2012

Matrilin-3 switches from anti- to pro-anabolic upon integration to the extracellular matrix.

artículo científico publicado en 2012

Metabolism of Parabens (4-Hydroxybenzoic Acid Esters) by Hepatic Esterases and UDP-Glucuronosyltransferases in Man

artículo científico publicado el 1 de enero de 2010

Mitogen-inducible gene-6 partly mediates the inhibitory effects of prenatal dexamethasone exposure on endochondral ossification in long bones of fetal rats

scientific article published on 29 April 2016

Modifications of the glycosaminoglycan-linkage region of proteoglycans: phosphorylation and sulfation determine the activity of the human beta1,4-galactosyltransferase 7 and beta1,3-glucuronosyltransferase I.

artículo científico publicado en 2005

Modulation of xylosyltransferase I expression provides a mechanism regulating glycosaminoglycan chain synthesis during cartilage destruction and repair

scientific journal article

Molecular basis for acceptor substrate specificity of the human beta1,3-glucuronosyltransferases GlcAT-I and GlcAT-P involved in glycosaminoglycan and HNK-1 carbohydrate epitope biosynthesis, respectively

scientific article published on 13 June 2007

Nicotine-induced retardation of chondrogenesis through down-regulation of IGF-1 signaling pathway to inhibit matrix synthesis of growth plate chondrocytes in fetal rats

scientific journal article

Osteogenic differentiation of human bone marrow mesenchymal stem cells in hydrogel containing nacre powder.

artículo científico publicado en 2013

Phosphorylation and sulfation of oligosaccharide substrates critically influence the activity of human beta1,4-galactosyltransferase 7 (GalT-I) and beta1,3-glucuronosyltransferase I (GlcAT-I) involved in the biosynthesis of the glycosaminoglycan-pro

artículo científico publicado en 2004

Phylogenetic and mutational analyses reveal key residues for UDP-glucuronic acid binding and activity of beta1,3-glucuronosyltransferase I (GlcAT-I)

artículo científico publicado en 2006

Prenatal caffeine exposure induces a poor quality of articular cartilage in male adult offspring rats via cholesterol accumulation in cartilage

artículo científico publicado en 2015

Prenatal ethanol exposure increases osteoarthritis susceptibility in female rat offspring by programming a low-functioning IGF-1 signaling pathway

artículo científico publicado en 2015

Prenatal ethanol exposure induces the osteoarthritis-like phenotype in female adult offspring rats with a post-weaning high-fat diet and its intrauterine programming mechanisms of cholesterol metabolism

artículo científico publicado en 2015

Prenatal ethanol exposure programs an increased susceptibility of non-alcoholic fatty liver disease in female adult offspring rats

artículo científico publicado en 2013

Prenatal food restriction induces poor-quality articular cartilage in female rat offspring fed a post-weaning high-fat diet and its intra-uterine programming mechanisms

artículo científico publicado en 2016

Prenatal nicotine exposure enhances the susceptibility to metabolic syndrome in adult offspring rats fed high-fat diet via alteration of HPA axis-associated neuroendocrine metabolic programming

artículo científico publicado en 2013

Prenatal nicotine exposure induces poor articular cartilage quality in female adult offspring fed a high-fat diet and the intrauterine programming mechanisms

artículo científico publicado en 2016

Prenatal nicotine exposure intergenerationally programs imperfect articular cartilage via histone deacetylation through maternal lineage.

artículo científico publicado en 2018

Preparation and characterization of liposomes incorporating cucurbitacin E, a natural cytotoxic triterpene

artículo científico publicado en 2013

Purification and characterization of a soluble form of the recombinant human galactose-beta1,3-glucuronosyltransferase I expressed in the yeast Pichia pastoris

artículo científico publicado en 2005

Regulation of xylosyltransferase I gene expression by interleukin 1β in human primary chondrocyte cells: mechanism and impact on proteoglycan synthesis

artículo científico publicado en 2012

Response to 'TNF/TNFR signal transduction pathway-mediated anti-apoptosis and anti-inflammatory effects of sodium ferulate on IL-1β-induced rat osteoarthritis chondrocytes in vitro'--authors' reply

artículo científico publicado en 2013

Resveratrol is efficiently glucuronidated by UDP-glucuronosyltransferases in the human gastrointestinal tract and in Caco-2 cells

artículo científico publicado en 2006

Reviewing the binding of a series of parabens to human serum albumin

artículo científico publicado en 2013

Stability of cucurbitacin E in human plasma: chemical hydrolysis and role of plasma esterases

artículo científico publicado en 2009

Structure of UDP-glucuronosyltransferases in membranes

artículo científico publicado en 2005

Subchondral bone dysplasia partly participates in prenatal dexamethasone induced-osteoarthritis susceptibility in female offspring rats

artículo científico publicado en 2020

Substrate specificity of the human UDP-glucuronosyltransferase UGT2B4 and UGT2B7. Identification of a critical aromatic amino acid residue at position 33

artículo científico publicado en 2007

Synergistic antifibrotic effect of verapamil and interferon-gamma in rats: partially based on enhanced verapamil oral bioavailability

artículo científico publicado en 2010

TNF/TNFR signal transduction pathway-mediated anti-apoptosis and anti-inflammatory effects of sodium ferulate on IL-1β-induced rat osteoarthritis chondrocytes in vitro

artículo científico publicado en 2012

The UDP-glucuronosyltransferases of the blood-brain barrier: their role in drug metabolism and detoxication

artículo científico publicado en 2014

The critical role of UDP-galactose-4-epimerase in osteoarthritis: modulating proteoglycans synthesis of the articular chondrocytes

artículo científico publicado en 2014

The cucurbitacins E, D and I: investigation of their cytotoxicity toward human chondrosarcoma SW 1353 cell line and their biotransformation in man liver

artículo científico publicado en 2012

The donor substrate specificity of the human beta 1,3-glucuronosyltransferase I toward UDP-glucuronic acid is determined by two crucial histidine and arginine residues

artículo científico publicado en 2002

The effects of levofloxacin on rabbit anterior cruciate ligament cells in vitro

artículo científico publicado en 2011

The effects of levofloxacin on rabbit fibroblast-like synoviocytes in vitro

artículo científico publicado en 2012

The functional glycosyltransferase signature sequence of the human beta 1,3-glucuronosyltransferase is a XDD motif

artículo científico publicado en 2003

The human UDP-glucuronosyltransferases: structural aspects and drug glucuronidation

artículo científico publicado en 2003

The importance of cysteine 126 in the human liver UDP-glucuronosyltransferase UGT1A6.

artículo científico publicado en 2002

The stop transfer sequence of the human UDP-glucuronosyltransferase 1A determines localization to the endoplasmic reticulum by both static retention and retrieval mechanisms

artículo científico publicado en 2005

The use of hepatocytes to investigate UDP-glucuronosyltransferases and sulfotransferases

artículo científico publicado en 2010

Thermodynamic insights into the structural basis governing the donor substrate recognition by human beta1,4-galactosyltransferase 7.

artículo científico publicado en 2009

UDP-glucose dehydrogenase modulates proteoglycan synthesis in articular chondrocytes: its possible involvement and regulation in osteoarthritis

artículo científico publicado en 2014

Xylosyltransferase-I regulates glycosaminoglycan synthesis during the pathogenic process of human osteoarthritis

artículo científico publicado en 2012

[Agrecan and articular cartilage: assessment of glycosyltransferases for the restoration of cartilage matrix in osteoarthritis]

artículo científico publicado en 2008

[Chondrocyte glycosyltransferases: new pharmacological targets for degenerative diseases of articular cartilage?]

scientific article published on 01 October 2006

[Stimulation of proteoglycan synthesis towards cartilage repair]

artículo científico publicado en 2005

cis- and trans-Resveratrol are glucuronidated in rat brain, olfactory mucosa and cultured astrocytes

artículo científico publicado en 2007

p-Hydroxybenzoate esters metabolism in MCF7 breast cancer cells

artículo científico publicado en 2012