Lista de obras -

A chemical approach to "rewire" neural progenitor cells

artículo científico publicado en 2014

A cut above the rest: targeted genome editing technologies in human pluripotent stem cells

artículo científico publicado en 2013

A genome-wide CRISPR-based screen identifies <i>KAT7</i> as a driver of cellular senescence

artículo científico publicado en 2021

A human circulating immune cell landscape in aging and COVID-19

artículo científico publicado en 2020

A novel suppressive effect of alcohol dehydrogenase 5 in neuronal differentiation

artículo científico publicado en 2014

A single-cell transcriptomic landscape of primate arterial aging

scientific article published on 05 May 2020

A widely adaptable approach to generate integration-free iPSCs from non-invasively acquired human somatic cells

artículo científico publicado en 2015

A β-galactosidase kiss of death for senescent cells

artículo científico publicado en 2020

ALKBH1 deficiency leads to loss of homeostasis in human diploid somatic cells

artículo científico publicado en 2020

ATF6 safeguards organelle homeostasis and cellular aging in human mesenchymal stem cells

artículo científico publicado en 2018

Aging stem cells. A Werner syndrome stem cell model unveils heterochromatin alterations as a driver of human aging

artículo científico publicado en 2015

Aging weakens Th17 cell pathogenicity and ameliorates experimental autoimmune uveitis in mice

artículo científico publicado en 2021

Autophagic control of cell ‘stemness’ ⬇️

artículo científico publicado el 1 de marzo de 2013

BMAL1 moonlighting as a gatekeeper for LINE1 repression and cellular senescence in primates

artículo científico publicado en 2022

Beating in a dish: new hopes for cardiomyocyte regeneration

artículo científico publicado en 2012

CRISPR/Cas9-mediated targeted gene correction in amyotrophic lateral sclerosis patient iPSCs.

artículo científico publicado en 2017

Chemical screen identifies a geroprotective role of quercetin in premature aging

scientific article published on 01 August 2018

Concealing cellular defects in pluripotent stem cells ⬇️

artículo científico publicado el 1 de agosto de 2013

Cord blood-derived neuronal cells by ectopic expression of Sox2 and c-Myc

artículo científico publicado en 2012

Correction to: mTORC2/RICTOR exerts differential levels of metabolic control in human embryonic, mesenchymal and neural stem cells

artículo científico publicado en 2022

Cross-species metabolomic analysis identifies uridine as a potent regeneration promoting factor

artículo científico publicado en 2022

Cut and paste: restoring cellular function by gene correction

artículo científico publicado en 2011

Deciphering primate retinal aging at single-cell resolution

artículo científico publicado en 2020

Differential stem cell aging kinetics in Hutchinson-Gilford progeria syndrome and Werner syndrome

artículo científico publicado en 2018

Direct conversion of human fibroblasts into retinal pigment epithelium-like cells by defined factors

artículo científico publicado en 2014

Direct reprogramming of porcine fibroblasts to neural progenitor cells

artículo científico publicado en 2014

Ectopic hTERT expression facilitates reprograming of fibroblasts derived from patients with Werner syndrome as a WS cellular model

artículo científico publicado en 2018

Efficient correction of hemoglobinopathy-causing mutations by homologous recombination in integration-free patient iPSCs

artículo científico publicado en 2011

Establishment of hepatic and neural differentiation platforms of Wilson’s disease specific induced pluripotent stem cells ⬇️

artículo científico publicado el 18 de julio de 2012

Gametogenesis in a dish

artículo científico publicado en 2012

Gating neural development and aging via nuclear pores ⬇️

artículo científico publicado el 13 de marzo de 2012

Gating pluripotency via nuclear pores

artículo científico publicado en 2013

Genetic enhancement in cultured human adult stem cells conferred by a single nucleotide recoding

artículo científico publicado en 2017

Global DNA methylation and transcriptional analyses of human ESC-derived cardiomyocytes

artículo científico publicado en 2014

Human induced pluripotent stem cells derived hepatocytes: rising promise for disease modeling, drug development and cell therapy ⬇️

artículo científico publicado el 22 de marzo de 2012

Huntington's disease: Dancing in a dish ⬇️

artículo científico publicado el 7 de agosto de 2012

In vivo genome editing via CRISPR/Cas9 mediated homology-independent targeted integration

artículo científico publicado en 2016

Induced neural stem cells: a new tool for studying neural development and neurological disorders

artículo científico publicado en 2012

LRRK2 functions as a scaffolding kinase of ASK1-mediated neuronal cell death.

artículo científico publicado en 2017

Lack of consensus on an aging biology paradigm? A global survey reveals an agreement to disagree, and the need for an interdisciplinary framework

artículo científico publicado en 2020

Metformin alleviates human cellular aging by upregulating the endoplasmic reticulum glutathione peroxidase 7

artículo científico publicado en 2018

Mitochondrial Regulation in Pluripotent Stem Cells ⬇️

artículo científico publicado el 11 de julio de 2013

Modeling xeroderma pigmentosum associated neurological pathologies with patients-derived iPSCs

artículo científico publicado en 2016

Modelling Fanconi anemia pathogenesis and therapeutics using integration-free patient-derived iPSCs

artículo científico publicado en 2014

Navigating the epigenetic landscape of pluripotent stem cells ⬇️

artículo científico publicado el 23 de julio de 2012

New march towards the regeneration of sensation and cognition: hear more, see more and learn more ⬇️

artículo científico publicado el 6 de diciembre de 2012

PTEN deficiency reprogrammes human neural stem cells towards a glioblastoma stem cell-like phenotype

artículo científico publicado en 2015

Post-translational modulation of pluripotency ⬇️

artículo científico publicado el 7 de junio de 2012

Precise in vivo genome editing via single homology arm donor mediated intron-targeting gene integration for genetic disease correction

artículo científico publicado en 2019

Progressive degeneration of human neural stem cells caused by pathogenic LRRK2

artículo científico publicado en 2012

Protein quality control of cell stemness

scientific article published on 12 November 2020

Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndrome

artículo científico publicado en 2011

Regeneration: making muscle from hPSCs

artículo científico publicado en 2014

Regenerative medicine: targeted genome editing in vivo

artículo científico publicado en 2015

Regenerative medicine: transdifferentiation in vivo

artículo científico publicado en 2013

Regulation of Stem Cell Aging by Metabolism and Epigenetics

artículo científico publicado en 2017

Rejuvenating liver and pancreas through cell transdifferentiation ⬇️

artículo científico publicado el 28 de febrero de 2012

Reprogramming based gene therapy for inherited red blood cell disorders ⬇️

artículo científico publicado el 3 de abril de 2012

SIRT3 consolidates heterochromatin and counteracts senescence

artículo científico publicado en 2021

SIRT7 antagonizes human stem cell aging as a heterochromatin stabilizer

artículo científico publicado en 2020

Selective elimination of mitochondrial mutations in the germline by genome editing

artículo científico publicado en 2015

Single-cell omics in ageing: a young and growing field

artículo científico publicado en 2020

Single-cell transcriptomic atlas of primate cardiopulmonary aging

scientific article published on 10 September 2020

Stabilization of heterochromatin by CLOCK promotes stem cell rejuvenation and cartilage regeneration

artículo científico publicado en 2020

Stabilizing heterochromatin by DGCR8 alleviates senescence and osteoarthritis

artículo científico publicado en 2019

Super-resolution fluorescence-assisted diffraction computational tomography reveals the three-dimensional landscape of the cellular organelle interactome

artículo científico publicado en 2020

Targeted gene correction of laminopathy-associated LMNA mutations in patient-specific iPSCs

artículo científico publicado en 2011

The ageing epigenome and its rejuvenation

scientific article published on 04 February 2020

The conundrum of human immune system "senescence"

scientific article published on 16 September 2020

The dawn of angiogenesis modeling: regenerating vasculature from human pluripotent stem cells ⬇️

artículo científico publicado el 11 de septiembre de 2012

Treating osteoarthritis via gene therapy with rejuvenation factors

artículo científico publicado en 2020

Up-regulation of FOXD1 by YAP alleviates senescence and osteoarthritis

scientific article published on 01 April 2019

Wiskott-Aldrich syndrome protein forms nuclear condensates and regulates alternative splicing

artículo científico publicado en 2022

hESC-derived pancreatic progenitors ⬇️

artículo científico publicado el 5 de febrero de 2013

iPSC technology to study human aging and aging-related disorders ⬇️

artículo científico publicado el 18 de septiembre de 2012

mTORC2/RICTOR exerts differential levels of metabolic control in human embryonic, mesenchymal and neural stem cells

artículo científico publicado en 2022

αKLOTHO and sTGFβR2 treatment counteract the osteoarthritic phenotype developed in a rat model

artículo científico publicado en 2020

“TET-on” pluripotency ⬇️

artículo científico publicado el 4 de junio de 2013

Lista de obras de

A chemical approach to "rewire" neural progenitor cells

A cut above the rest: targeted genome editing technologies in human pluripotent stem cells

A genome-wide CRISPR-based screen identifies <i>KAT7</i> as a driver of cellular senescence

A human circulating immune cell landscape in aging and COVID-19

A novel suppressive effect of alcohol dehydrogenase 5 in neuronal differentiation

A single-cell transcriptomic landscape of primate arterial aging

A widely adaptable approach to generate integration-free iPSCs from non-invasively acquired human somatic cells

A β-galactosidase kiss of death for senescent cells

ALKBH1 deficiency leads to loss of homeostasis in human diploid somatic cells

ATF6 safeguards organelle homeostasis and cellular aging in human mesenchymal stem cells

Aging stem cells. A Werner syndrome stem cell model unveils heterochromatin alterations as a driver of human aging

Aging weakens Th17 cell pathogenicity and ameliorates experimental autoimmune uveitis in mice

Autophagic control of cell ‘stemness’ ⬇️

BMAL1 moonlighting as a gatekeeper for LINE1 repression and cellular senescence in primates

Beating in a dish: new hopes for cardiomyocyte regeneration

CRISPR/Cas9-mediated targeted gene correction in amyotrophic lateral sclerosis patient iPSCs.

Chemical screen identifies a geroprotective role of quercetin in premature aging

Concealing cellular defects in pluripotent stem cells ⬇️

Cord blood-derived neuronal cells by ectopic expression of Sox2 and c-Myc

Correction to: mTORC2/RICTOR exerts differential levels of metabolic control in human embryonic, mesenchymal and neural stem cells

Cross-species metabolomic analysis identifies uridine as a potent regeneration promoting factor

Cut and paste: restoring cellular function by gene correction

Deciphering primate retinal aging at single-cell resolution

Differential stem cell aging kinetics in Hutchinson-Gilford progeria syndrome and Werner syndrome

Direct conversion of human fibroblasts into retinal pigment epithelium-like cells by defined factors

Direct reprogramming of porcine fibroblasts to neural progenitor cells

Ectopic hTERT expression facilitates reprograming of fibroblasts derived from patients with Werner syndrome as a WS cellular model

Efficient correction of hemoglobinopathy-causing mutations by homologous recombination in integration-free patient iPSCs

Establishment of hepatic and neural differentiation platforms of Wilson’s disease specific induced pluripotent stem cells ⬇️

Gametogenesis in a dish

Gating neural development and aging via nuclear pores ⬇️

Gating pluripotency via nuclear pores

Genetic enhancement in cultured human adult stem cells conferred by a single nucleotide recoding

Global DNA methylation and transcriptional analyses of human ESC-derived cardiomyocytes

Human induced pluripotent stem cells derived hepatocytes: rising promise for disease modeling, drug development and cell therapy ⬇️

Huntington's disease: Dancing in a dish ⬇️

In vivo genome editing via CRISPR/Cas9 mediated homology-independent targeted integration

Induced neural stem cells: a new tool for studying neural development and neurological disorders

LRRK2 functions as a scaffolding kinase of ASK1-mediated neuronal cell death.

Lack of consensus on an aging biology paradigm? A global survey reveals an agreement to disagree, and the need for an interdisciplinary framework

Metformin alleviates human cellular aging by upregulating the endoplasmic reticulum glutathione peroxidase 7

Mitochondrial Regulation in Pluripotent Stem Cells ⬇️

Modeling xeroderma pigmentosum associated neurological pathologies with patients-derived iPSCs

Modelling Fanconi anemia pathogenesis and therapeutics using integration-free patient-derived iPSCs

Navigating the epigenetic landscape of pluripotent stem cells ⬇️

New march towards the regeneration of sensation and cognition: hear more, see more and learn more ⬇️

PTEN deficiency reprogrammes human neural stem cells towards a glioblastoma stem cell-like phenotype

Post-translational modulation of pluripotency ⬇️

Precise in vivo genome editing via single homology arm donor mediated intron-targeting gene integration for genetic disease correction

Progressive degeneration of human neural stem cells caused by pathogenic LRRK2

Protein quality control of cell stemness

Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndrome

Regeneration: making muscle from hPSCs

Regenerative medicine: targeted genome editing in vivo

Regenerative medicine: transdifferentiation in vivo

Regulation of Stem Cell Aging by Metabolism and Epigenetics

Rejuvenating liver and pancreas through cell transdifferentiation ⬇️

Reprogramming based gene therapy for inherited red blood cell disorders ⬇️

SIRT3 consolidates heterochromatin and counteracts senescence

SIRT7 antagonizes human stem cell aging as a heterochromatin stabilizer

Selective elimination of mitochondrial mutations in the germline by genome editing

Single-cell omics in ageing: a young and growing field

Single-cell transcriptomic atlas of primate cardiopulmonary aging

Stabilization of heterochromatin by CLOCK promotes stem cell rejuvenation and cartilage regeneration

Stabilizing heterochromatin by DGCR8 alleviates senescence and osteoarthritis

Super-resolution fluorescence-assisted diffraction computational tomography reveals the three-dimensional landscape of the cellular organelle interactome

Targeted gene correction of laminopathy-associated LMNA mutations in patient-specific iPSCs

The ageing epigenome and its rejuvenation

The conundrum of human immune system "senescence"

The dawn of angiogenesis modeling: regenerating vasculature from human pluripotent stem cells ⬇️

Treating osteoarthritis via gene therapy with rejuvenation factors

Up-regulation of FOXD1 by YAP alleviates senescence and osteoarthritis

Wiskott-Aldrich syndrome protein forms nuclear condensates and regulates alternative splicing

hESC-derived pancreatic progenitors ⬇️

iPSC technology to study human aging and aging-related disorders ⬇️

mTORC2/RICTOR exerts differential levels of metabolic control in human embryonic, mesenchymal and neural stem cells

αKLOTHO and sTGFβR2 treatment counteract the osteoarthritic phenotype developed in a rat model

“TET-on” pluripotency ⬇️