Lista de obras -

(-)-Homosalinosporamide A and Its Mode of Proteasome Inhibition: An X-ray Crystallographic Study

scientific article published on 19 July 2018

<i>Necator americanus Ancylostoma</i> Secreted Protein-2 (<i>Na</i>-ASP-2) Binds an Ascaroside (ascr#3) in Its Fatty Acid Binding Site

scientific article published on 17 December 2020

A Highly Diastereoselective, Tandem Mukaiyama Aldol-Lactonization Route to beta-Lactones: Application to a Concise Synthesis of the Potent Pancreatic Lipase Inhibitor, (-)-Panclicin D

scientific article published on 01 January 1997

A Novel Actin Binding Drug with Efficacy

artículo científico publicado en 2018

A beta-lactone route to chiral gamma-substituted alpha-amino acids: application to the concise synthesis of (S)-alpha-azidobutyro lactone and a natural amino acid

artículo científico publicado en 2002

A chemifluorescent immunoassay for the determination of marinobufagenin in body fluids

artículo científico publicado en 2011

A diastereoselective, nucleophile-promoted aldol-lactonization of ketoacids leading to bicyclic-β-lactones

artículo científico publicado en 2012

A strategy for dual inhibition of the proteasome and fatty acid synthase with belactosin C-orlistat hybrids

artículo científico publicado en 2017

A(1,3)-strain enabled retention of chirality during bis-cyclization of beta-ketoamides: total synthesis of (-)-salinosporamide A and (-)-homosalinosporamide A.

artículo científico publicado en 2010

Acylammonium salts as dienophiles in Diels-Alder/lactonization organocascades.

artículo científico publicado en 2014

Alkyl C-O ring cleavage of bicyclic beta-lactones with Normant reagents: synthesis of a Merck IND intermediate.

artículo científico publicado en 2007

Asymmetric Organocatalysis: The Emerging Utility of α,β-Unsaturated Acylammonium Salts.

artículo científico publicado en 2016

Asymmetric synthesis of bicyclic beta-lactones via the intramolecular, nucleophile-catalyzed aldol lactonization: improved efficiency and expanded scope

artículo científico publicado en 2005

Asymmetric synthesis, structure, and reactivity of unexpectedly stable spiroepoxy-beta-lactones including facile conversion to tetronic acids: application to (+)-maculalactone A.

artículo científico publicado en 2009

Beta-lactam congeners of orlistat as inhibitors of fatty acid synthase

artículo científico publicado en 2008

Bicyclic- and tricyclic-beta-lactones via organonucleophile-promoted bis-cyclizations of keto acids: Enantioselective synthesis of (+)-dihydroplakevulin

artículo científico publicado en 2006

Bioactive Seco-Lanostane-Type Triterpenoids from the Roots of Leplaea mayombensis.

artículo científico publicado en 2017

Bioinspired Total Synthesis and Human Proteasome Inhibitory Activity of (−)-Salinosporamide A, (−)-Homosalinosporamide A, and Derivatives Obtained via Organonucleophile Promoted Bis-cyclizations ⬇️

artículo científico publicado el 3 de noviembre de 2010

Bioinspired total synthesis of agelastatin A.

artículo científico publicado en 2012

Biosynthesis, asymmetric synthesis, and pharmacology, including cellular targets, of the pyrrole-2-aminoimidazole marine alkaloids ⬇️

artículo científico publicado el 9 de mayo de 2011

Bridging the gap between natural product synthesis and drug discovery

artículo científico publicado en 2020

Chemical Mechanism of the Phosphotriesterase from Sphingobium sp. Strain TCM1, an Enzyme Capable of Hydrolyzing Organophosphate Flame Retardants

artículo científico publicado en 2016

Chemo- and site-selective derivatizations of natural products enabling biological studies

artículo científico publicado en 2014

Comparison of Alicyclobacillus acidocaldarius o-Succinylbenzoate Synthase to Its Promiscuous N-Succinylamino Acid Racemase/ o-Succinylbenzoate Synthase Relatives

artículo científico publicado en 2018

Concise synthesis of spirocyclic, bridged gamma-butyrolactones via stereospecific, dyotropic rearrangements of beta-lactones involving 1,2-acyl and delta-lactone migrations

artículo científico publicado en 2008

Concise synthesis of the isothiourea organocatalysts homobenzotetramisole and derivatives

artículo científico publicado en 2013

Concise total synthesis of (+)-brefeldin A: a combined beta-lactone/cross-metathesis-based strategy

artículo científico publicado en 2002

Concise total synthesis of (+/-)-salinosporamide A, (+/-)-cinnabaramide A, and derivatives via a bis-cyclization process: implications for a biosynthetic pathway?

artículo científico publicado en 2007

Correction: Piperlongumine Blocks JAK2-STAT3 to Inhibit Collagen-Induced Platelet Reactivity Independent of Reactive Oxygen Species†.

artículo científico publicado en 2016

Covalent modification of a cysteine residue in the XPB subunit of the general transcription factor TFIIH through single epoxide cleavage of the transcription inhibitor triptolide

artículo científico publicado en 2014

Creating novel translation inhibitors to target pro-survival proteins in chronic lymphocytic leukemia

artículo científico publicado en 2019

Cyclopropanations of olefin-containing natural products for simultaneous arming and structure activity studies

artículo científico publicado en 2012

Cyclosporin A treatment of Leishmania donovani reveals stage-specific functions of cyclophilins in parasite proliferation and viability

artículo científico publicado en 2010

De novo synthesis of benzosceptrin C and nagelamide H from 7-15N-oroidin: implications for pyrrole-aminoimidazole alkaloid biosynthesis

artículo científico publicado en 2012

Derivatization of agelastatin A leading to bioactive analogs and a trifunctional probe

artículo científico publicado en 2016

Diastereo- and Enantioselective Synthesis of Bi- and Tricyclic N-Heterocycle-Fused β-Lactones.

artículo científico publicado en 2017

Diastereoselective synthesis of tetrahydrofurans via mead reductive cyclization of keto-beta-lactones derived from the tandem Mukaiyama aldol lactonization (TMAL) process

artículo científico publicado en 2007

Diastereoselective, three-component cascade synthesis of tetrahydrofurans and tetrahydropyrans employing the tandem Mukaiyama aldol-lactonization process

artículo científico publicado en 2008

Diastereoselective, vinylogous mukaiyama aldol additions of silyloxy furans to cyclic ketones: annulation of butenolides and gamma-lactones

artículo científico publicado en 2006

Diazo Reagents with Small Steric Footprints for Simultaneous Arming/SAR Studies of Alcohol-Containing Natural Products via O–H Insertion ⬇️

artículo científico publicado el 28 de septiembre de 2011

Direct catalytic asymmetric synthesis of N-heterocycles from commodity acid chlorides by employing α,β-unsaturated acylammonium salts

artículo científico publicado en 2013

Double diastereoselective, nucleophile-catalyzed aldol lactonizations (NCAL) leading to beta-lactone fused carbocycles and extensions to beta-lactone fused tetrahydrofurans

artículo científico publicado en 2010

Dyotropic rearrangements of fused tricyclic β-lactones: application to the synthesis of (-)-curcumanolide A and (-)-curcumalactone

artículo científico publicado en 2012

Editorial: Strategies for cellular target identification of natural products.

artículo científico publicado en 2016

Enantioselective Diels-Alder-lactamization organocascades employing a furan-based diene.

artículo científico publicado en 2017

Enantioselective Synthesis of Medium-Sized Lactams Employing Chiral Alpha,Beta-Unsaturated Acylammonium Salts.

artículo científico publicado en 2018

Enantioselective synthesis of (+)-monobromophakellin and (+)-phakellin: a concise phakellin annulation strategy applicable to Palau'amine

scientific article published on 01 January 2008

Enantioselective synthesis of schulzeines B and C via a beta-lactone-derived surrogate for bishomoserine aldehyde

artículo científico publicado en 2009

Enantioselective total synthesis of (+)-dibromophakellstatin

artículo científico publicado en 2003

Enantioselective total synthesis of the marine toxin (-)-gymnodimine employing a Barbier-type macrocyclization

artículo científico publicado en 2009

Enantioselective, Organocatalytic Strategy for the Oxazolomycin Core: Formal Synthesis of (+)-Neooxazolomycin

artículo científico publicado en 2020

Enantioselective, Organocatalyzed, Intramolecular Aldol Lactonizations with Keto Acids Leading to Bi‐ and Tricyclic β‐Lactones and Topology‐Morphing Transformations ⬇️

artículo científico publicado el 3 de diciembre de 2010

Eukaryotic initiation factor 2alpha-independent pathway of stress granule induction by the natural product pateamine A.

artículo científico publicado en 2006

Evidence for separate binding and scaffolding domains in the immunosuppressive and antitumor marine natural product, pateamine a: design, synthesis, and activity studies leading to a potent simplified derivative

artículo científico publicado en 2004

Facile synthesis of the trans-fused azabicyclo[3.3.0]octane core of the palau'amines and the tricyclic core of the axinellamines from a common intermediate

artículo científico publicado en 2008

Functional mimicry revealed by the crystal structure of an eIF4A:RNA complex bound to the interfacial inhibitor, desmethyl pateamine A

artículo científico publicado en 2021

Generation and Reactivity of 2-Amido-1,3-diaminoallyl Cations: Cyclic Guanidine Annulations via Net (3 + 2) and (4 + 3) Cycloadditions

artículo científico publicado en 2020

Gracilin A Derivatives Target Early Events in Alzheimer's Disease: in Vitro Effects on Neuroinflammation and Oxidative Stress

scientific article published on 23 August 2019

Herpes Simplex Virus 2 Virion Host Shutoff Endoribonuclease Activity Is Required To Disrupt Stress Granule Formation.

artículo científico publicado en 2016

Highly diastereoselective desymmetrizations of cyclo(Pro,Pro): an enantioselective strategy toward phakellstatin and phakellin

artículo científico publicado en 2002

Highly diastereoselective, tandem, three-component synthesis of tetrahydrofurans from ketoaldehydes via silylated beta-lactone intermediates

artículo científico publicado en 2008

Highly regioselective Diels-Alder reactions toward oroidin alkaloids: use of a tosylvinyl moiety as a nitrogen masking group with adjustable electronics

scientific article published on 01 April 2005

Inhibition of Eukaryotic Translation by the Antitumor Natural Product Agelastatin A.

artículo científico publicado en 2017

Inhibition of eukaryotic translation initiation by the marine natural product pateamine A.

artículo científico publicado en 2005

Interrogating translational efficiency and lineage-specific transcriptomes using ribosome affinity purification

artículo científico publicado en 2013

Interrogation of the Substrate Profile and Catalytic Properties of the Phosphotriesterase from Sphingobium sp. Strain TCM1: An Enzyme Capable of Hydrolyzing Organophosphate Flame Retardants and Plasticizers.

artículo científico publicado en 2015

Investigation of the mechanism of action of a potent pateamine A analog, des-methyl, des-amino pateamine A (DMDAPatA)

artículo científico publicado en 2020

Isolation and identification of eukaryotic initiation factor 4A as a molecular target for the marine natural product Pateamine A.

artículo científico publicado en 2007

Isolation, Derivative Synthesis, and Structure-Activity Relationships of Antiparasitic Bromopyrrole Alkaloids from the Marine Sponge Tedania brasiliensis

artículo científico publicado en 2018

Marinobufagenin Levels in Preeclamptic Patients: A Preliminary Report ⬇️

artículo científico publicado el 4 de marzo de 2011

Mechanism and origin of stereoselectivity in Lewis acid catalyzed [2 + 2] cycloadditions of ketenes with aldehydes

artículo científico publicado en 2002

Mechanistic investigations of the ZnCl2-mediated tandem Mukaiyama aldol lactonization: evidence for asynchronous, concerted transition states and discovery of 2-oxopyridyl ketene acetal variants

artículo científico publicado en 2012

Mild Deprotection of Primary N-(p-Toluenesulfonyl) Amides with SmI2 Following Trifluoroacetylation

Mild arming and derivatization of natural products via an In(OTf)3-catalyzed arene iodination

artículo científico publicado en 2010

Molecular Mechanism for Attractant Signaling to DHMA by E. coli Tsr

artículo científico publicado en 2019

Multicomponent, Enantioselective Michael-Michael-Aldol-β-Lactonizations Delivering Complex β-Lactones.

artículo científico publicado en 2017

Natural-product synthesis: stitching together palau'amine

artículo científico publicado en 2010

Pharmacophore-Directed Retrosynthesis Applied to Ophiobolin A: Simplified Bicyclic Derivatives Displaying Anticancer Activity

scientific article published on 09 October 2020

Pharmacophore-Directed Retrosynthesis Applied to Rameswaralide: Synthesis and Bioactivity of Sinularia Natural Product Tricyclic Cores

artículo científico publicado en 2019

Piperlongumine Blocks JAK2-STAT3 to Inhibit Collagen-Induced Platelet Reactivity Independent of Reactive Oxygen Species

artículo científico publicado en 2015

Potent in vitro and in vivo anticancer activities of des-methyl, des-amino pateamine A, a synthetic analogue of marine natural product pateamine A

artículo científico publicado en 2009

Practical, catalytic, asymmetric synthesis of beta-lactones via a sequential ketene dimerization/hydrogenation process: inhibitors of the thioesterase domain of fatty acid synthase

scientific article published on 01 June 2006

Promiscuity of Exiguobacterium sp. AT1b o-succinylbenzoate synthase illustrates evolutionary transitions in the OSBS family

artículo científico publicado en 2014

Pyrrole aminoimidazole alkaloid metabiosynthesis with marine sponges Agelas conifera and Stylissa caribica

scientific article published on 04 April 2012

Quantitative chemoproteomic profiling reveals multiple target interactions of spongiolactone derivatives in leukemia cells. ⬇️

artículo científico publicado en 2017

Rapid assembly of complex cyclopentanes employing chiral, α,β-unsaturated acylammonium intermediates.

artículo científico publicado en 2013

Role of an active site loop in the promiscuous activities of Amycolatopsis sp. T-1-60 NSAR/OSBS.

artículo científico publicado en 2014

Second-generation derivatives of the eukaryotic translation initiation inhibitor pateamine A targeting eIF4A as potential anticancer agents

artículo científico publicado en 2013

Simplified immunosuppressive and neuroprotective agents based on gracilin A

scientific article published on 22 March 2019

Simultaneous Arming and Structure/Activity Studies of Natural Products Employing O−H Insertions: An Expedient and Versatile Strategy for Natural Products-Based Chemical Genetics

article

Simultaneous structure-activity studies and arming of natural products by C-H amination reveal cellular targets of eupalmerin acetate

artículo científico publicado en 2013

Stereodivergent, Diels-Alder-initiated organocascades employing α,β-unsaturated acylammonium salts: scope, mechanism, and application.

artículo científico publicado en 2016

Studies toward a marine toxin immunogen: enantioselective synthesis of the spirocyclic imine of (-)-gymnodimine

artículo científico publicado en 2005

Substrate-dependent targeting of eukaryotic translation initiation factor 4A by pateamine A: negation of domain-linker regulation of activity.

artículo científico publicado en 2007

Switching between concerted and stepwise mechanisms for dyotropic rearrangements of β-lactones leading to spirocyclic, bridged γ-butyrolactones.

artículo científico publicado en 2011

Synthesis of (±)-spongiolactone enabling discovery of a more potent derivative.

artículo científico publicado en 2014

Synthesis of 7-(15)N-Oroidin and evaluation of utility for biosynthetic studies of pyrrole-imidazole alkaloids by microscale (1)H-(15)N HSQC and FTMS

artículo científico publicado en 2010

Synthesis of Unusually Strained Spiro Ring Systems and Their Exploits in Synthesis

artículo científico publicado en 2009

Synthesis of novel beta-lactone inhibitors of fatty acid synthase

artículo científico

Synthesis, characterization, and utility of thermoresponsive natural/unnatural product macroligands for affinity chromatography

artículo científico publicado en 2006

Synthesis, structure, and reactivity of unexpectedly stable spiroepoxy-beta-lactones obtained by epoxidation of 4-alkylidene-2-oxetanones

artículo científico publicado en 2005

Synthetic Tigliane Intermediates Engage Thiols to Induce Potent Cell Line Selective Anti-Cancer Activity

artículo científico publicado en 2020

Synthetic strategies for mining the information-rich content of natural products for biology and medicine

artículo científico publicado en 2020

The ever-expanding role of asymmetric covalent organocatalysis in scalable, natural product synthesis

artículo científico publicado en 2014

Total Synthesis and Anticancer Activity of (+)-Hypercalin C and Congeners

scientific article published on 01 February 2019

Total Synthesis of (+)‐Omphadiol ⬇️

artículo científico publicado el 14 de julio de 2011

Total Synthesis of the Spirocyclic Imine Marine Toxin (−)-Gymnodimine and an Unnatural C4-Epimer ⬇️

artículo científico publicado el 16 de noviembre de 2011

Total synthesis and comparative analysis of orlistat, valilactone, and a transposed orlistat derivative: Inhibitors of fatty acid synthase

artículo científico publicado en 2006

Total synthesis of (-)-belactosin C and derivatives via double diastereoselective tandem mukaiyama aldol lactonizations

artículo científico publicado en 2007

Transformation of fused bicyclic and tricyclic beta-lactones to fused gamma-lactones and 3(2H)-furanones via ring expansions and O-H insertions

artículo científico publicado en 2007

Translation initiation factors GleIF4E2 and GleIF4A can interact directly with the components of the pre-initiation complex to facilitate translation initiation in Giardia lamblia

artículo científico publicado en 2020

Triptolide: reflections on two decades of research and prospects for the future

artículo científico publicado en 2020

Waixenicin A, a marine-derived TRPM7 inhibitor: a promising CNS drug lead

artículo científico publicado en 2020

Lista de obras de

(-)-Homosalinosporamide A and Its Mode of Proteasome Inhibition: An X-ray Crystallographic Study

<i>Necator americanus Ancylostoma</i> Secreted Protein-2 (<i>Na</i>-ASP-2) Binds an Ascaroside (ascr#3) in Its Fatty Acid Binding Site

A Highly Diastereoselective, Tandem Mukaiyama Aldol-Lactonization Route to beta-Lactones: Application to a Concise Synthesis of the Potent Pancreatic Lipase Inhibitor, (-)-Panclicin D

A Novel Actin Binding Drug with Efficacy

A beta-lactone route to chiral gamma-substituted alpha-amino acids: application to the concise synthesis of (S)-alpha-azidobutyro lactone and a natural amino acid

A chemifluorescent immunoassay for the determination of marinobufagenin in body fluids

A diastereoselective, nucleophile-promoted aldol-lactonization of ketoacids leading to bicyclic-β-lactones

A strategy for dual inhibition of the proteasome and fatty acid synthase with belactosin C-orlistat hybrids

A(1,3)-strain enabled retention of chirality during bis-cyclization of beta-ketoamides: total synthesis of (-)-salinosporamide A and (-)-homosalinosporamide A.

Acylammonium salts as dienophiles in Diels-Alder/lactonization organocascades.

Alkyl C-O ring cleavage of bicyclic beta-lactones with Normant reagents: synthesis of a Merck IND intermediate.

Asymmetric Organocatalysis: The Emerging Utility of α,β-Unsaturated Acylammonium Salts.

Asymmetric synthesis of bicyclic beta-lactones via the intramolecular, nucleophile-catalyzed aldol lactonization: improved efficiency and expanded scope

Asymmetric synthesis, structure, and reactivity of unexpectedly stable spiroepoxy-beta-lactones including facile conversion to tetronic acids: application to (+)-maculalactone A.

Beta-lactam congeners of orlistat as inhibitors of fatty acid synthase

Bicyclic- and tricyclic-beta-lactones via organonucleophile-promoted bis-cyclizations of keto acids: Enantioselective synthesis of (+)-dihydroplakevulin

Bioactive Seco-Lanostane-Type Triterpenoids from the Roots of Leplaea mayombensis.

Bioinspired Total Synthesis and Human Proteasome Inhibitory Activity of (−)-Salinosporamide A, (−)-Homosalinosporamide A, and Derivatives Obtained via Organonucleophile Promoted Bis-cyclizations ⬇️

Bioinspired total synthesis of agelastatin A.

Biosynthesis, asymmetric synthesis, and pharmacology, including cellular targets, of the pyrrole-2-aminoimidazole marine alkaloids ⬇️

Bridging the gap between natural product synthesis and drug discovery

Chemical Mechanism of the Phosphotriesterase from Sphingobium sp. Strain TCM1, an Enzyme Capable of Hydrolyzing Organophosphate Flame Retardants

Chemo- and site-selective derivatizations of natural products enabling biological studies

Comparison of Alicyclobacillus acidocaldarius o-Succinylbenzoate Synthase to Its Promiscuous N-Succinylamino Acid Racemase/ o-Succinylbenzoate Synthase Relatives

Concise synthesis of spirocyclic, bridged gamma-butyrolactones via stereospecific, dyotropic rearrangements of beta-lactones involving 1,2-acyl and delta-lactone migrations

Concise synthesis of the isothiourea organocatalysts homobenzotetramisole and derivatives

Concise total synthesis of (+)-brefeldin A: a combined beta-lactone/cross-metathesis-based strategy

Concise total synthesis of (+/-)-salinosporamide A, (+/-)-cinnabaramide A, and derivatives via a bis-cyclization process: implications for a biosynthetic pathway?

Correction: Piperlongumine Blocks JAK2-STAT3 to Inhibit Collagen-Induced Platelet Reactivity Independent of Reactive Oxygen Species†.

Covalent modification of a cysteine residue in the XPB subunit of the general transcription factor TFIIH through single epoxide cleavage of the transcription inhibitor triptolide

Creating novel translation inhibitors to target pro-survival proteins in chronic lymphocytic leukemia

Cyclopropanations of olefin-containing natural products for simultaneous arming and structure activity studies

Cyclosporin A treatment of Leishmania donovani reveals stage-specific functions of cyclophilins in parasite proliferation and viability

De novo synthesis of benzosceptrin C and nagelamide H from 7-15N-oroidin: implications for pyrrole-aminoimidazole alkaloid biosynthesis

Derivatization of agelastatin A leading to bioactive analogs and a trifunctional probe

Diastereo- and Enantioselective Synthesis of Bi- and Tricyclic N-Heterocycle-Fused β-Lactones.

Diastereoselective synthesis of tetrahydrofurans via mead reductive cyclization of keto-beta-lactones derived from the tandem Mukaiyama aldol lactonization (TMAL) process

Diastereoselective, three-component cascade synthesis of tetrahydrofurans and tetrahydropyrans employing the tandem Mukaiyama aldol-lactonization process

Diastereoselective, vinylogous mukaiyama aldol additions of silyloxy furans to cyclic ketones: annulation of butenolides and gamma-lactones

Diazo Reagents with Small Steric Footprints for Simultaneous Arming/SAR Studies of Alcohol-Containing Natural Products via O–H Insertion ⬇️

Direct catalytic asymmetric synthesis of N-heterocycles from commodity acid chlorides by employing α,β-unsaturated acylammonium salts

Double diastereoselective, nucleophile-catalyzed aldol lactonizations (NCAL) leading to beta-lactone fused carbocycles and extensions to beta-lactone fused tetrahydrofurans

Dyotropic rearrangements of fused tricyclic β-lactones: application to the synthesis of (-)-curcumanolide A and (-)-curcumalactone

Editorial: Strategies for cellular target identification of natural products.

Enantioselective Diels-Alder-lactamization organocascades employing a furan-based diene.

Enantioselective Synthesis of Medium-Sized Lactams Employing Chiral Alpha,Beta-Unsaturated Acylammonium Salts.

Enantioselective synthesis of (+)-monobromophakellin and (+)-phakellin: a concise phakellin annulation strategy applicable to Palau'amine

Enantioselective synthesis of schulzeines B and C via a beta-lactone-derived surrogate for bishomoserine aldehyde

Enantioselective total synthesis of (+)-dibromophakellstatin

Enantioselective total synthesis of the marine toxin (-)-gymnodimine employing a Barbier-type macrocyclization

Enantioselective, Organocatalytic Strategy for the Oxazolomycin Core: Formal Synthesis of (+)-Neooxazolomycin

Enantioselective, Organocatalyzed, Intramolecular Aldol Lactonizations with Keto Acids Leading to Bi‐ and Tricyclic β‐Lactones and Topology‐Morphing Transformations ⬇️

Eukaryotic initiation factor 2alpha-independent pathway of stress granule induction by the natural product pateamine A.

Evidence for separate binding and scaffolding domains in the immunosuppressive and antitumor marine natural product, pateamine a: design, synthesis, and activity studies leading to a potent simplified derivative

Facile synthesis of the trans-fused azabicyclo[3.3.0]octane core of the palau'amines and the tricyclic core of the axinellamines from a common intermediate

Functional mimicry revealed by the crystal structure of an eIF4A:RNA complex bound to the interfacial inhibitor, desmethyl pateamine A

Generation and Reactivity of 2-Amido-1,3-diaminoallyl Cations: Cyclic Guanidine Annulations via Net (3 + 2) and (4 + 3) Cycloadditions

Gracilin A Derivatives Target Early Events in Alzheimer's Disease: in Vitro Effects on Neuroinflammation and Oxidative Stress

Herpes Simplex Virus 2 Virion Host Shutoff Endoribonuclease Activity Is Required To Disrupt Stress Granule Formation.

Highly diastereoselective desymmetrizations of cyclo(Pro,Pro): an enantioselective strategy toward phakellstatin and phakellin

Highly diastereoselective, tandem, three-component synthesis of tetrahydrofurans from ketoaldehydes via silylated beta-lactone intermediates

Highly regioselective Diels-Alder reactions toward oroidin alkaloids: use of a tosylvinyl moiety as a nitrogen masking group with adjustable electronics

Inhibition of Eukaryotic Translation by the Antitumor Natural Product Agelastatin A.

Inhibition of eukaryotic translation initiation by the marine natural product pateamine A.

Interrogating translational efficiency and lineage-specific transcriptomes using ribosome affinity purification

Interrogation of the Substrate Profile and Catalytic Properties of the Phosphotriesterase from Sphingobium sp. Strain TCM1: An Enzyme Capable of Hydrolyzing Organophosphate Flame Retardants and Plasticizers.

Investigation of the mechanism of action of a potent pateamine A analog, des-methyl, des-amino pateamine A (DMDAPatA)

Isolation and identification of eukaryotic initiation factor 4A as a molecular target for the marine natural product Pateamine A.

Isolation, Derivative Synthesis, and Structure-Activity Relationships of Antiparasitic Bromopyrrole Alkaloids from the Marine Sponge Tedania brasiliensis

Marinobufagenin Levels in Preeclamptic Patients: A Preliminary Report ⬇️

Mechanism and origin of stereoselectivity in Lewis acid catalyzed [2 + 2] cycloadditions of ketenes with aldehydes

Mechanistic investigations of the ZnCl2-mediated tandem Mukaiyama aldol lactonization: evidence for asynchronous, concerted transition states and discovery of 2-oxopyridyl ketene acetal variants

Mild Deprotection of Primary N-(p-Toluenesulfonyl) Amides with SmI2 Following Trifluoroacetylation

Mild arming and derivatization of natural products via an In(OTf)3-catalyzed arene iodination

Molecular Mechanism for Attractant Signaling to DHMA by E. coli Tsr

Multicomponent, Enantioselective Michael-Michael-Aldol-β-Lactonizations Delivering Complex β-Lactones.

Natural-product synthesis: stitching together palau'amine

Pharmacophore-Directed Retrosynthesis Applied to Ophiobolin A: Simplified Bicyclic Derivatives Displaying Anticancer Activity

Pharmacophore-Directed Retrosynthesis Applied to Rameswaralide: Synthesis and Bioactivity of Sinularia Natural Product Tricyclic Cores