Lista de obras -

A new lead to NLRP3 inhibition

artículo científico publicado en 2017

A20 critically controls microglia activation and inhibits inflammasome-dependent neuroinflammation.

artículo científico publicado en 2018

Blood-based test for diagnosis and functional subtyping of familial Mediterranean fever

artículo científico publicado en 2020

Complementarity and redundancy of IL-22-producing innate lymphoid cells.

artículo científico publicado en 2015

DPP8/DPP9 inhibition elicits canonical Nlrp1b inflammasome hallmarks in murine macrophages

artículo científico publicado en 2019

Escherichia coli Rho GTPase-activating toxin CNF1 mediates NLRP3 inflammasome activation via p21-activated kinases-1/2 during bacteraemia in mice

artículo científico publicado en 2021

GSDMD is critical for autoinflammatory pathology in a mouse model of Familial Mediterranean Fever.

artículo científico publicado en 2018

Inflammasomes in neuroinflammatory and neurodegenerative diseases.

artículo científico publicado en 2019

MCC950/CRID3 potently targets the NACHT domain of wild-type NLRP3 but not disease-associated mutants for inflammasome inhibition

scientific article published on 16 September 2019

NLRP2 controls age-associated maternal fertility

artículo científico publicado en 2016

Prdx4 limits caspase-1 activation and restricts inflammasome-mediated signaling by extracellular vesicles

scientific article published on 23 September 2019

Single-cell analysis of pyroptosis dynamics reveals conserved GSDMD-mediated subcellular events that precede plasma membrane rupture.

artículo científico publicado en 2018

Structure of S-layer protein Sap reveals a mechanism for therapeutic intervention in anthrax

scientific article published on 15 July 2019

The emerging roles of inflammasome-dependent cytokines in cancer development

scientific article published on 17 May 2019

The transcription factor IRF1 and guanylate-binding proteins target activation of the AIM2 inflammasome by Francisella infection

artículo científico publicado en 2015

Therapeutic modulation of inflammasome pathways

artículo científico publicado en 2020

Two distinct ubiquitin-binding motifs in A20 mediate its anti-inflammatory and cell-protective activities

artículo científico publicado en 2020

Lista de obras de

A new lead to NLRP3 inhibition

A20 critically controls microglia activation and inhibits inflammasome-dependent neuroinflammation.

Blood-based test for diagnosis and functional subtyping of familial Mediterranean fever

Complementarity and redundancy of IL-22-producing innate lymphoid cells.

DPP8/DPP9 inhibition elicits canonical Nlrp1b inflammasome hallmarks in murine macrophages

Escherichia coli Rho GTPase-activating toxin CNF1 mediates NLRP3 inflammasome activation via p21-activated kinases-1/2 during bacteraemia in mice

GSDMD is critical for autoinflammatory pathology in a mouse model of Familial Mediterranean Fever.

Inflammasomes in neuroinflammatory and neurodegenerative diseases.

MCC950/CRID3 potently targets the NACHT domain of wild-type NLRP3 but not disease-associated mutants for inflammasome inhibition

NLRP2 controls age-associated maternal fertility

Prdx4 limits caspase-1 activation and restricts inflammasome-mediated signaling by extracellular vesicles

Single-cell analysis of pyroptosis dynamics reveals conserved GSDMD-mediated subcellular events that precede plasma membrane rupture.

Structure of S-layer protein Sap reveals a mechanism for therapeutic intervention in anthrax

The emerging roles of inflammasome-dependent cytokines in cancer development

The transcription factor IRF1 and guanylate-binding proteins target activation of the AIM2 inflammasome by Francisella infection

Therapeutic modulation of inflammasome pathways

Two distinct ubiquitin-binding motifs in A20 mediate its anti-inflammatory and cell-protective activities