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2-Methylene 19-nor-25-dehydro-1alpha-hydroxyvitamin D3 26,23-lactones: synthesis, biological activities and molecular basis of passive antagonism

artículo científico publicado en 2007

22-Alkyl-20-epi-1alpha,25-dihydroxyvitamin D3 compounds of superagonistic activity: syntheses, biological activities and interaction with the receptor

artículo científico publicado en 2007

Central Insulin Action Activates Kupffer Cells by Suppressing Hepatic Vagal Activation via the Nicotinic Alpha 7 Acetylcholine Receptor.

artículo científico publicado en 2016

Chronic activation of FXR in transgenic mice caused perinatal toxicity and sensitized mice to cholesterol toxicity.

artículo científico publicado en 2015

Diet Intake Control Is Indispensable for the Gluconeogenic Response to Sodium-Glucose Cotransporter 2 Inhibition in Male Mice

artículo científico publicado en 2020

Dietary Mung Bean Protein Reduces Hepatic Steatosis, Fibrosis, and Inflammation in Male Mice with Diet-Induced, Nonalcoholic Fatty Liver Disease.

artículo científico publicado en 2016

Dietary soybean protein ameliorates high-fat diet-induced obesity by modifying the gut microbiota-dependent biotransformation of bile acids

artículo científico publicado en 2018

Fine tuning of agonistic/antagonistic activity for vitamin D receptor by 22-alkyl chain length of ligands: 22S-Hexyl compound unexpectedly restored agonistic activity

artículo científico publicado en 2015

Hepatic Gluconeogenic Response to Single and Long-Term SGLT2 Inhibition in Lean/Obese Male Hepatic G6pc-Reporter Mice

scientific article published on 01 December 2019

MAPK Erk5 in Leptin Receptor‒Expressing Neurons Controls Body Weight and Systemic Energy Homeostasis in Female Mice

scientific article published on 01 December 2019

Nicotinic alpha 7 acetylcholine receptor deficiency exacerbates hepatic inflammation and fibrosis in a mouse model of nonalcoholic steatohepatitis

scientific article published on 16 December 2018

PDGFRβ Regulates Adipose Tissue Expansion and Glucose Metabolism via Vascular Remodeling in Diet-Induced Obesity

artículo científico publicado en 2017

PHD3 regulates glucose metabolism by suppressing stress-induced signalling and optimising gluconeogenesis and insulin signalling in hepatocytes

scientific article published in Scientific Reports

Sirt2 facilitates hepatic glucose uptake by deacetylating glucokinase regulatory protein.

artículo científico publicado en 2018

Structural basis for inhibition of carboxypeptidase B by selenium-containing inhibitor: selenium coordinates to zinc in enzyme

artículo científico publicado en 2013

Tissue Specific Induction of p62/Sqstm1 by Farnesoid X Receptor

artículo científico publicado el 27 de agosto de 2012

Vitamin D3 derivatives with adamantane or lactone ring side chains are cell type-selective vitamin D receptor modulators

artículo científico publicado en 2007

p62/SQSTM1 plays a protective role in oxidative injury of steatotic liver in a mouse hepatectomy model

artículo científico publicado en 2014