Lista de obras -

A Transgenic Mouse Model of Pacak⁻Zhuang Syndrome with An Epas1 Gain-of-Function Mutation

scientific article published on 14 May 2019

A novel splicing site IRP1 somatic mutation in a patient with pheochromocytoma and JAK2V617F positive polycythemia vera: a case report.

artículo científico publicado en 2018

Acetylation within the N- and C-terminal domains of Src regulate distinct roles of STAT3-mediated tumorigenesis.

artículo científico publicado en 2018

Activation of hypoxia signaling induces phenotypic transformation of glioma cells: implications for bevacizumab antiangiogenic therapy

artículo científico publicado en 2015

Anthracyclines suppress pheochromocytoma cell characteristics, including metastasis, through inhibition of the hypoxia signaling pathway

artículo científico publicado en 2017

Application of Peptide Nucleic Acid-based Assays Toward Detection of Somatic Mosaicism

artículo científico publicado en 2016

Blockade of Glutathione Metabolism in IDH1-Mutated Glioma

artículo científico publicado en 2019

Brusatol, an NRF2 inhibitor for future cancer therapeutic.

artículo científico publicado en 2019

Carbon dioxide influence on nitric oxide production in endothelial cells and astrocytes: Cellular mechanisms ⬇️

artículo científico publicado el 26 de febrero de 2011

Celastrol increases glucocerebrosidase activity in Gaucher disease by modulating molecular chaperones.

artículo científico publicado en 2013

Characterization of the blood-brain barrier of metastatic and primary malignant neoplasms.

artículo científico publicado en 2013

Chemosensitivity of IDH1-Mutated Gliomas Due to an Impairment in PARP1-Mediated DNA Repair

artículo científico

Combination of PARP inhibitor and temozolomide to suppress chordoma progression

scientific article published on 14 June 2019

De novo VHL germline mutation detected in a patient with mild clinical phenotype of von Hippel-Lindau disease

artículo científico publicado en 2014

Evaluating In Vitro DNA Damage Using Comet Assay

artículo científico publicado en 2017

First report of bilateral pheochromocytoma in the clinical spectrum of HIF2A-related polycythemia-paraganglioma syndrome.

artículo científico publicado en 2013

HIF2A gain-of-function mutations detected in duodenal gangliocytic paraganglioma.

artículo científico publicado en 2016

Histone deacetylase inhibitors prevent the degradation and restore the activity of glucocerebrosidase in Gaucher disease ⬇️

artículo científico publicado el 12 de diciembre de 2011

Inhibition of protein phosphatase 2A with the small molecule LB100 overcomes cell cycle arrest in osteosarcoma after cisplatin treatment.

artículo científico publicado en 2015

Isocitrate Dehydrogenase Mutations in Glioma: Genetics, Biochemistry, and Clinical Indications

artículo científico publicado en 2020

LB100, a small molecule inhibitor of PP2A with potent chemo- and radio-sensitizing potential

artículo científico publicado en 2015

Mutant glucocerebrosidase in Gaucher disease recruits Hsp27 to the Hsp90 chaperone complex for proteasomal degradation

artículo científico publicado en 2015

New developments in the pathogenesis and therapeutic targeting of the IDH1 mutation in glioma

artículo científico publicado en 2015

New syndrome of paraganglioma and somatostatinoma associated with polycythemia

artículo científico publicado en 2013

Nonmosaic somatic HIF2A mutations associated with late onset polycythemia-paraganglioma syndrome: Newly recognized subclass of polycythemia-paraganglioma syndrome

artículo científico publicado en 2019

Novel Targeting of Transcription and Metabolism in Glioblastoma

artículo científico publicado en 2017

Novel homozygous VHL mutation in exon 2 is associated with congenital polycythemia but not with cancer.

artículo científico publicado en 2013

Novel insights into the polycythemia-paraganglioma-somatostatinoma syndrome

artículo científico publicado en 2016

Pheochromocytomas and Paragangliomas: From Genetic Diversity to Targeted Therapies

scientific article published on 28 March 2019

Protein Phosphatase 2A Inhibition with LB100 Enhances Radiation-Induced Mitotic Catastrophe and Tumor Growth Delay in Glioblastoma.

artículo científico publicado en 2015

Somatic HIF2A gain-of-function mutations in paraganglioma with polycythemia

artículo científico publicado en 2012

Somatic IDH1 mutation in a pituitary adenoma of a patient with Maffucci syndrome

artículo científico publicado en 2015

Targeting IDH1-Mutated Malignancies with NRF2 Blockade

artículo científico publicado en 2019

Targeting NAD+/PARP DNA repair pathway as a novel therapeutic approach to SDHB-mutated cluster I pheochromocytoma and paraganglioma.

artículo científico publicado en 2018

Targeting NRF2-Governed Glutathione Synthesis for SDHB-Mutated Pheochromocytoma and Paraganglioma

artículo científico publicado en 2020

The p38 signaling pathway mediates quiescence of glioma stem cells by regulating epidermal growth factor receptor trafficking

artículo científico publicado en 2017

Therapeutic targeting of SDHB-mutated pheochromocytoma/paraganglioma with pharmacologic ascorbic acid

scientific article published on 09 March 2020

Triptolide suppresses IDH1-mutated malignancy via Nrf2-driven glutathione metabolism

artículo científico publicado en 2020

Tumor derived vasculogenesis in von Hippel-Lindau disease-associated tumors.

artículo científico publicado en 2014

Vorinostat suppresses hypoxia signaling by modulating nuclear translocation of hypoxia inducible factor 1 alpha.

artículo científico publicado en 2017

ZEB1 expression is increased in IDH1-mutant lower-grade gliomas.

artículo científico

Lista de obras de

A Transgenic Mouse Model of Pacak⁻Zhuang Syndrome with An Epas1 Gain-of-Function Mutation

A novel splicing site IRP1 somatic mutation in a patient with pheochromocytoma and JAK2V617F positive polycythemia vera: a case report.

Acetylation within the N- and C-terminal domains of Src regulate distinct roles of STAT3-mediated tumorigenesis.

Activation of hypoxia signaling induces phenotypic transformation of glioma cells: implications for bevacizumab antiangiogenic therapy

Anthracyclines suppress pheochromocytoma cell characteristics, including metastasis, through inhibition of the hypoxia signaling pathway

Application of Peptide Nucleic Acid-based Assays Toward Detection of Somatic Mosaicism

Blockade of Glutathione Metabolism in IDH1-Mutated Glioma

Brusatol, an NRF2 inhibitor for future cancer therapeutic.

Carbon dioxide influence on nitric oxide production in endothelial cells and astrocytes: Cellular mechanisms ⬇️

Celastrol increases glucocerebrosidase activity in Gaucher disease by modulating molecular chaperones.

Characterization of the blood-brain barrier of metastatic and primary malignant neoplasms.

Chemosensitivity of IDH1-Mutated Gliomas Due to an Impairment in PARP1-Mediated DNA Repair

Combination of PARP inhibitor and temozolomide to suppress chordoma progression

De novo VHL germline mutation detected in a patient with mild clinical phenotype of von Hippel-Lindau disease

Evaluating In Vitro DNA Damage Using Comet Assay

First report of bilateral pheochromocytoma in the clinical spectrum of HIF2A-related polycythemia-paraganglioma syndrome.

HIF2A gain-of-function mutations detected in duodenal gangliocytic paraganglioma.

Histone deacetylase inhibitors prevent the degradation and restore the activity of glucocerebrosidase in Gaucher disease ⬇️

Inhibition of protein phosphatase 2A with the small molecule LB100 overcomes cell cycle arrest in osteosarcoma after cisplatin treatment.

Isocitrate Dehydrogenase Mutations in Glioma: Genetics, Biochemistry, and Clinical Indications

LB100, a small molecule inhibitor of PP2A with potent chemo- and radio-sensitizing potential

Mutant glucocerebrosidase in Gaucher disease recruits Hsp27 to the Hsp90 chaperone complex for proteasomal degradation

New developments in the pathogenesis and therapeutic targeting of the IDH1 mutation in glioma

New syndrome of paraganglioma and somatostatinoma associated with polycythemia

Nonmosaic somatic HIF2A mutations associated with late onset polycythemia-paraganglioma syndrome: Newly recognized subclass of polycythemia-paraganglioma syndrome

Novel Targeting of Transcription and Metabolism in Glioblastoma

Novel homozygous VHL mutation in exon 2 is associated with congenital polycythemia but not with cancer.

Novel insights into the polycythemia-paraganglioma-somatostatinoma syndrome

Pheochromocytomas and Paragangliomas: From Genetic Diversity to Targeted Therapies

Protein Phosphatase 2A Inhibition with LB100 Enhances Radiation-Induced Mitotic Catastrophe and Tumor Growth Delay in Glioblastoma.

Somatic HIF2A gain-of-function mutations in paraganglioma with polycythemia

Somatic IDH1 mutation in a pituitary adenoma of a patient with Maffucci syndrome

Targeting IDH1-Mutated Malignancies with NRF2 Blockade

Targeting NAD+/PARP DNA repair pathway as a novel therapeutic approach to SDHB-mutated cluster I pheochromocytoma and paraganglioma.

Targeting NRF2-Governed Glutathione Synthesis for SDHB-Mutated Pheochromocytoma and Paraganglioma

The p38 signaling pathway mediates quiescence of glioma stem cells by regulating epidermal growth factor receptor trafficking

Therapeutic targeting of SDHB-mutated pheochromocytoma/paraganglioma with pharmacologic ascorbic acid

Triptolide suppresses IDH1-mutated malignancy via Nrf2-driven glutathione metabolism

Tumor derived vasculogenesis in von Hippel-Lindau disease-associated tumors.

Vorinostat suppresses hypoxia signaling by modulating nuclear translocation of hypoxia inducible factor 1 alpha.

ZEB1 expression is increased in IDH1-mutant lower-grade gliomas.