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Addiction to DUSP1 protects JAK2V617F-driven polycythemia vera progenitors against inflammatory stress and DNA damage, allowing chronic proliferation

artículo científico publicado en 2019

Co-occurring V617F and R1063H mutations increase JAK2 signaling and neutrophilia in MPN patients

artículo científico publicado en 2018

Coexistence of gain-of-function JAK2 germ line mutations with JAK2V617F in polycythemia vera

artículo científico publicado en 2016

Differential sensitivity to JAK inhibitory drugs by isogenic human erythroblasts and hematopoietic progenitors generated from patient-specific induced pluripotent stem cells

artículo científico publicado en 2014

Evolutionary selected Tibetan variants of HIF pathway and risk of lung cancer.

artículo científico publicado en 2017

Experimental Modeling of Myeloproliferative Neoplasms

scientific article published on 15 October 2019

HIC1 Expression Distinguishes Intestinal Carcinomas Sensitive to Chemotherapy.

artículo científico publicado en 2016

Iron chelation and 2-oxoglutarate-dependent dioxygenase inhibition suppress mantle cell lymphoma's cyclin D1

scientific article published on 13 September 2019

Novel homozygous VHL mutation in exon 2 is associated with congenital polycythemia but not with cancer.

artículo científico publicado en 2013

Oxidative DNA Damage, Inflammatory Signature, and Altered Erythrocytes Properties in Diamond-Blackfan Anemia

artículo científico publicado en 2020

RUNX1 and NF-E2 upregulation is not specific for MPNs, but is seen in polycythemic disorders with augmented HIF signaling

artículo científico publicado en 2013

The homozygous VHL(D126N) missense mutation is associated with dramatically elevated erythropoietin levels, consequent polycythemia, and early onset severe pulmonary hypertension.

artículo científico publicado en 2014

The relationship of JAK2(V617F) and acquired UPD at chromosome 9p in polycythemia vera.

artículo científico publicado en 2014

Wnt Effector TCF4 Is Dispensable for Wnt Signaling in Human Cancer Cells

article

β-Thalassemia due to intronic LINE-1 insertion in the β-globin gene (HBB): molecular mechanisms underlying reduced transcript levels of the β-globin(L1) allele

artículo científico publicado en 2013

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