Lista de obras -

Autologous bone marrow stromal cells genetically engineered to secrete an igf-I receptor decoy prevent the growth of liver metastases

artículo científico publicado en 2009

Biological effects of growth hormone on carbohydrate and lipid metabolism.

artículo científico publicado en 2009

Central effects of humanin on hepatic triglyceride secretion

artículo científico publicado en 2015

Circulating IGF-1 and its role in cancer: lessons from the IGF-1 gene deletion (LID) mouse.

artículo científico publicado en 2004

Circulating levels of IGF-1 directly regulate bone growth and density

artículo científico publicado en 2002

Clinical relevance of systemic and local IGF-I.

artículo científico publicado en 2005

Does the GH/IGF-1 axis contribute to skeletal sexual dimorphism? Evidence from mouse studies.

artículo científico publicado en 2015

Effects of GH/IGF on the Aging Mitochondria

artículo científico publicado en 2020

Elevated circulating IGF-I promotes mammary gland development and proliferation

artículo científico publicado en 2010

Elevated levels of insulin-like growth factor (IGF)-I in serum rescue the severe growth retardation of IGF-I null mice

artículo científico publicado en 2009

Elevated serum IGF-1 levels synergize PTH action on the skeleton only when the tissue IGF-1 axis is intact.

artículo científico publicado en 2010

Elevated serum levels of IGF-1 are sufficient to establish normal body size and skeletal properties even in the absence of tissue IGF-1.

artículo científico publicado en 2010

Energy-preserving effects of IGF-1 antagonize starvation-induced cardiac autophagy

artículo científico publicado en 2011

From mouse to man: redefining the role of insulin-like growth factor-I in the acquisition of bone mass.

artículo científico publicado en 2003

Genetic reduction of circulating insulin-like growth factor-1 inhibits azoxymethane-induced colon tumorigenesis in mice

artículo científico publicado en 2009

Growth hormone protects against ovariectomy-induced bone loss in states of low circulating insulin-like growth factor (IGF-1).

artículo científico publicado en 2010

Growth hormone receptor regulates β cell hyperplasia and glucose-stimulated insulin secretion in obese mice

artículo científico publicado en 2011

Growth hormone regulates the balance between bone formation and bone marrow adiposity

artículo científico publicado en 2010

High-efficient FLPo deleter mice in C57BL/6J background

artículo científico publicado en 2009

Hyperinsulinemia enhances c-Myc-mediated mammary tumor development and advances metastatic progression to the lung in a mouse model of type 2 diabetes ⬇️

artículo científico publicado el 7 de enero de 2012

Hyperinsulinemia promotes metastasis to the lung in a mouse model of Her2-mediated breast cancer

artículo científico publicado en 2013

IGF-1 and bone: New discoveries from mouse models

artículo científico publicado en 2010

Increased serum IGF-1 levels protect the musculoskeletal system but are associated with elevated oxidative stress markers and increased mortality independent of tissue igf1 gene expression

artículo científico publicado en 2011

Induction of somatopause in adult mice compromises bone morphology and exacerbates bone loss during aging

artículo científico publicado en 2021

Inhibition of growth hormone action improves insulin sensitivity in liver IGF-1-deficient mice

artículo científico publicado en 2004

Insulin-like growth factor 1 physiology: lessons from mouse models

artículo científico publicado en 2012

Insulin-like growth factor 1 receptor signaling regulates skin development and inhibits skin keratinocyte differentiation

scientific journal article

Insulin-like growth factor-I regulates the liver microenvironment in obese mice and promotes liver metastasis

artículo científico publicado en 2010

Insulin-like growth factor-I: compartmentalization within the somatotropic axis?

artículo científico publicado en 2002

Insulin-mediated acceleration of breast cancer development and progression in a nonobese model of type 2 diabetes

artículo científico publicado en 2010

Insulin-sensitizing therapy attenuates type 2 diabetes-mediated mammary tumor progression

artículo científico publicado en 2009

Low IGF-I Bioavailability Impairs Growth and Glucose Metabolism in a Mouse Model of Human PAPPA2 p.Ala1033Val Mutation

scientific article published on 01 June 2019

Mammalian target of rapamycin inhibition abrogates insulin-mediated mammary tumor progression in type 2 diabetes

artículo científico publicado en 2010

Murine osteosarcoma primary tumour growth and metastatic progression is maintained after marked suppression of serum insulin-like growth factor I.

artículo científico publicado en 2009

Osteocyte Apoptosis Caused by Hindlimb Unloading is Required to Trigger Osteocyte RANKL Production and Subsequent Resorption of Cortical and Trabecular Bone in Mice Femurs

artículo científico publicado en 2016

Reductions in serum IGF-1 during aging impair health span.

artículo científico publicado en 2013

Regulation of skeletal growth and mineral acquisition by the GH/IGF-1 axis: Lessons from mouse models.

artículo científico publicado en 2015

Serum IGF-1 affects skeletal acquisition in a temporal and compartment-specific manner

artículo científico publicado en 2011

Sex-specific regulation of body size and bone slenderness by the acid labile subunit

artículo científico publicado en 2010

Skeletal growth and bone mineral acquisition in type 1 diabetic children; abnormalities of the GH/IGF-1 axis.

artículo científico publicado en 2017

Skeletal muscle growth hormone receptor signaling regulates basal, but not fasting-induced, lipid oxidation

artículo científico publicado en 2012

TDAG51 mediates the effects of insulin-like growth factor I (IGF-I) on cell survival

artículo científico publicado en 2004

Targeted deletion of hepatic Igf1 in TRAMP mice leads to dramatic alterations in the circulating insulin-like growth factor axis but does not reduce tumor progression

artículo científico publicado en 2008

Targeted loss of GHR signaling in mouse skeletal muscle protects against high-fat diet-induced metabolic deterioration

artículo científico publicado en 2012

The effect of dipeptidyl peptidase-IV inhibition on bone in a mouse model of type 2 diabetes

artículo científico publicado en 2014

The growth hormone-insulin like growth factor axis revisited: lessons from IGF-1 and IGF-1 receptor gene targeting

artículo científico publicado en 2005

The insulin-like growth factor-1 binding protein acid-labile subunit alters mesenchymal stromal cell fate

artículo científico publicado en 2009

The intricate role of growth hormone in metabolism.

artículo científico publicado en 2011

The role of circulating IGF-I: lessons from human and animal models

artículo científico publicado en 2002

The role of the growth hormone/insulin-like growth factor axis in tumor growth and progression: Lessons from animal models

artículo científico publicado en 2005

Type 2 diabetic mice demonstrate slender long bones with increased fragility secondary to increased osteoclastogenesis

artículo científico publicado en 2008

Unbound (bioavailable) IGF1 enhances somatic growth.

artículo científico publicado en 2011

Lista de obras de

Autologous bone marrow stromal cells genetically engineered to secrete an igf-I receptor decoy prevent the growth of liver metastases

Biological effects of growth hormone on carbohydrate and lipid metabolism.

Central effects of humanin on hepatic triglyceride secretion

Circulating IGF-1 and its role in cancer: lessons from the IGF-1 gene deletion (LID) mouse.

Circulating levels of IGF-1 directly regulate bone growth and density

Clinical relevance of systemic and local IGF-I.

Does the GH/IGF-1 axis contribute to skeletal sexual dimorphism? Evidence from mouse studies.

Effects of GH/IGF on the Aging Mitochondria

Elevated circulating IGF-I promotes mammary gland development and proliferation

Elevated levels of insulin-like growth factor (IGF)-I in serum rescue the severe growth retardation of IGF-I null mice

Elevated serum IGF-1 levels synergize PTH action on the skeleton only when the tissue IGF-1 axis is intact.

Elevated serum levels of IGF-1 are sufficient to establish normal body size and skeletal properties even in the absence of tissue IGF-1.

Energy-preserving effects of IGF-1 antagonize starvation-induced cardiac autophagy

From mouse to man: redefining the role of insulin-like growth factor-I in the acquisition of bone mass.

Genetic reduction of circulating insulin-like growth factor-1 inhibits azoxymethane-induced colon tumorigenesis in mice

Growth hormone protects against ovariectomy-induced bone loss in states of low circulating insulin-like growth factor (IGF-1).

Growth hormone receptor regulates β cell hyperplasia and glucose-stimulated insulin secretion in obese mice

Growth hormone regulates the balance between bone formation and bone marrow adiposity

High-efficient FLPo deleter mice in C57BL/6J background

Hyperinsulinemia enhances c-Myc-mediated mammary tumor development and advances metastatic progression to the lung in a mouse model of type 2 diabetes ⬇️

Hyperinsulinemia promotes metastasis to the lung in a mouse model of Her2-mediated breast cancer

IGF-1 and bone: New discoveries from mouse models

Increased serum IGF-1 levels protect the musculoskeletal system but are associated with elevated oxidative stress markers and increased mortality independent of tissue igf1 gene expression

Induction of somatopause in adult mice compromises bone morphology and exacerbates bone loss during aging

Inhibition of growth hormone action improves insulin sensitivity in liver IGF-1-deficient mice

Insulin-like growth factor 1 physiology: lessons from mouse models

Insulin-like growth factor 1 receptor signaling regulates skin development and inhibits skin keratinocyte differentiation

Insulin-like growth factor-I regulates the liver microenvironment in obese mice and promotes liver metastasis

Insulin-like growth factor-I: compartmentalization within the somatotropic axis?

Insulin-mediated acceleration of breast cancer development and progression in a nonobese model of type 2 diabetes

Insulin-sensitizing therapy attenuates type 2 diabetes-mediated mammary tumor progression

Low IGF-I Bioavailability Impairs Growth and Glucose Metabolism in a Mouse Model of Human PAPPA2 p.Ala1033Val Mutation

Mammalian target of rapamycin inhibition abrogates insulin-mediated mammary tumor progression in type 2 diabetes

Murine osteosarcoma primary tumour growth and metastatic progression is maintained after marked suppression of serum insulin-like growth factor I.

Osteocyte Apoptosis Caused by Hindlimb Unloading is Required to Trigger Osteocyte RANKL Production and Subsequent Resorption of Cortical and Trabecular Bone in Mice Femurs

Reductions in serum IGF-1 during aging impair health span.

Regulation of skeletal growth and mineral acquisition by the GH/IGF-1 axis: Lessons from mouse models.

Serum IGF-1 affects skeletal acquisition in a temporal and compartment-specific manner

Sex-specific regulation of body size and bone slenderness by the acid labile subunit

Skeletal growth and bone mineral acquisition in type 1 diabetic children; abnormalities of the GH/IGF-1 axis.

Skeletal muscle growth hormone receptor signaling regulates basal, but not fasting-induced, lipid oxidation

TDAG51 mediates the effects of insulin-like growth factor I (IGF-I) on cell survival

Targeted deletion of hepatic Igf1 in TRAMP mice leads to dramatic alterations in the circulating insulin-like growth factor axis but does not reduce tumor progression

Targeted loss of GHR signaling in mouse skeletal muscle protects against high-fat diet-induced metabolic deterioration

The effect of dipeptidyl peptidase-IV inhibition on bone in a mouse model of type 2 diabetes

The growth hormone-insulin like growth factor axis revisited: lessons from IGF-1 and IGF-1 receptor gene targeting

The insulin-like growth factor-1 binding protein acid-labile subunit alters mesenchymal stromal cell fate

The intricate role of growth hormone in metabolism.

The role of circulating IGF-I: lessons from human and animal models

The role of the growth hormone/insulin-like growth factor axis in tumor growth and progression: Lessons from animal models

Type 2 diabetic mice demonstrate slender long bones with increased fragility secondary to increased osteoclastogenesis

Unbound (bioavailable) IGF1 enhances somatic growth.