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Characterization of a Linked Jumonji Domain of the KDM5/JARID1 Family of Histone H3 Lysine 4 Demethylases.

artículo científico publicado en 2015

Conformational Dynamics and Cooperativity Drive the Specificity of a Protein-Ligand Interaction

artículo científico publicado en 2019

Disruption of a key ligand-H-bond network drives dissociative properties in vamorolone for Duchenne muscular dystrophy treatment

scientific article published on 11 September 2020

Distinct Roles for Conformational Dynamics in Protein-Ligand Interactions

artículo científico publicado en 2016

Emerging Themes in PDZ Domain Signaling: Structure, Function, and Inhibition

artículo científico publicado en 2018

First High-Resolution Crystal Structures of the Glucocorticoid Receptor Ligand-Binding Domain-Peroxisome Proliferator-Activated γ Coactivator 1-α Complex with Endogenous and Synthetic Glucocorticoids

scientific article published on 07 August 2019

Insights into the Action of Inhibitor Enantiomers against Histone Lysine Demethylase 5A.

artículo científico publicado en 2018

Structural Basis for KDM5A Histone Lysine Demethylase Inhibition by Diverse Compounds

artículo científico publicado en 2016

Structural basis for glucocorticoid receptor recognition of both unmodified and methylated binding sites, precursors of a modern recognition element

artículo científico publicado en 2021

Structure-based engineering of irreversible inhibitors against histone lysine demethylase KDM5A

artículo científico publicado en 2018

The Structure of the Tiam1 PDZ Domain/ Phospho-Syndecan1 Complex Reveals a Ligand Conformation that Modulates Protein Dynamics

artículo científico publicado en 2013

The nuclear receptor superfamily: A structural perspective

artículo científico publicado en 2018