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"Direct to Drug" screening as a precision medicine tool in multiple myeloma

scientific article published on 11 May 2020

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one

artículo científico publicado en 2016

A Meta-analysis of Multiple Myeloma Risk Regions in African and European Ancestry Populations Identifies Putatively Functional Loci

artículo científico publicado en 2016

A Modern Primer on Light Chain Amyloidosis in 592 Patients With Mass Spectrometry-Verified Typing

scientific article published on 13 February 2019

A Phase II study of (153)Sm-EDTMP and high-dose melphalan as a peripheral blood stem cell conditioning regimen in patients with multiple myeloma

scientific article published on June 2010

A Phase Ib Study of the combination of the Aurora Kinase Inhibitor Alisertib (MLN8237) and Bortezomib in Relapsed Multiple Myeloma.

artículo científico publicado en 2015

A comparison of lenalidomide/dexamethasone versus cyclophosphamide/lenalidomide/dexamethasone versus cyclophosphamide/bortezomib/dexamethasone in newly diagnosed multiple myeloma

artículo científico publicado en 2011

A detailed evaluation of the current renal response criteria in AL amyloidosis: is it time for a revision?

artículo científico publicado en 2013

A dose-finding Phase 2 study of single agent isatuximab (anti-CD38 mAb) in relapsed/refractory multiple myeloma

artículo científico publicado en 2020

A gene expression signature distinguishes innate response and resistance to proteasome inhibitors in multiple myeloma

artículo científico publicado en 2017

A novel report of cig-FISH and cytogenetics in POEMS syndrome.

artículo científico publicado en 2008

A phase 2 study of lenalidomide, rituximab, cyclophosphamide, and dexamethasone (LR-CD) for untreated low-grade non-Hodgkin lymphoma requiring therapy

artículo científico publicado en 2017

A study from The Mayo Clinic evaluated long-term outcomes of kidney transplantation in patients with immunoglobulin light chain amyloidosis

artículo científico publicado en 2020

A validated composite organ and hematologic response model for early assessment of treatment outcomes in light chain amyloidosis

scientific article published on 14 April 2020

AT-101 downregulates BCL2 and MCL1 and potentiates the cytotoxic effects of lenalidomide and dexamethasone in preclinical models of multiple myeloma and Waldenström macroglobulinaemia

artículo científico publicado en 2013

Absolute values of immunoglobulin free light chains are prognostic in patients with primary systemic amyloidosis undergoing peripheral blood stem cell transplantation

artículo científico publicado en 2006

Activity of bortezomib administered once every 3 weeks for treatment of relapsed multiple myeloma.

artículo científico publicado en 2009

Activity of pomalidomide in patients with immunoglobulin light-chain amyloidosis

artículo científico publicado en 2012

Acute kidney injury during leukocyte engraftment after autologous stem cell transplantation in patients with light-chain amyloidosis

artículo científico publicado en 2011

African Americans with translocation t(11;14) have superior survival after autologous hematopoietic cell transplantation for multiple myeloma in comparison with Whites in the United States

scientific article published on 23 September 2020

Age no bar: A CIBMTR analysis of elderly patients undergoing autologous hematopoietic cell transplantation for multiple myeloma

scientific article published on 23 September 2020

Akt inhibitor MK2206 selectively targets CLL B-cell receptor induced cytokines, mobilizes lymphocytes and synergizes with bendamustine to induce CLL apoptosis

artículo científico publicado en 2013

All-oral ixazomib, cyclophosphamide, and dexamethasone for transplant-ineligible patients with newly diagnosed multiple myeloma

scientific article published on 22 November 2018

Altered cortical microarchitecture in patients with monoclonal gammopathy of undetermined significance

artículo científico publicado en 2013

An unusual neurological complication of light chain amyloidosis

scientific article published on 16 September 2009

Analysis of Clinical Factors and Outcomes Associated with Non-Utilization of Collected Peripheral Blood Stem Cells for Autologous Stem Cell Transplants in Transplant Eligible Patients with Multiple Myeloma.

artículo científico publicado en 2018

Anti-myeloma activity of Akt inhibition is linked to the activation status of PI3K/Akt and MEK/ERK pathway.

artículo científico publicado en 2012

Asymptomatic immunoglobulin light chain amyloidosis (AL) at the time of diagnostic bone marrow biopsy in newly diagnosed patients with multiple myeloma and smoldering myeloma. A series of 144 cases and a review of the literature

artículo científico publicado en 2010

Aurora kinase and FGFR3 inhibition results in significant apoptosis in molecular subgroups of multiple myeloma

Autologous Stem Cell Transplant for IgM-Associated Amyloid Light-Chain Amyloidosis

scholarly article by M Hasib Sidiqi et al published March 2019 in Biology of Blood and Marrow Transplantation

Autologous Stem Cell Transplant for Immunoglobulin Light Chain Amyloidosis Patients Aged 70 to 75

artículo científico publicado en 2018

Autologous stem cell transplant after heart transplant for light chain (Al) amyloid cardiomyopathy.

artículo científico publicado en 2008

Autologous stem cell transplant for immunoglobulin light chain amyloidosis: a status report

artículo científico publicado en 2010

Autologous stem cell transplant in 716 patients with multiple myeloma: low treatment-related mortality, feasibility of outpatient transplant, and effect of a multidisciplinary quality initiative

artículo científico publicado en 2008

Autologous stem cell transplantation for multiple myeloma patients aged ≥ 75 treated with novel agents

artículo científico publicado en 2020

Autologous stem cell transplantation in immunoglobulin light chain amyloidosis with factor X deficiency

artículo científico publicado en 2015

Autologous stem cell transplantation in patients of 70 years and older with multiple myeloma: Results from a matched pair analysis.

artículo científico publicado en 2008

Autologous stem cell transplantation in patients with AL amyloidosis with impaired renal function

scientific article published on 08 April 2019

Azaspirane (N-N-diethyl-8,8-dipropyl-2-azaspiro [4.5] decane-2-propanamine) inhibits human multiple myeloma cell growth in the bone marrow milieu in vitro and in vivo

artículo científico publicado en 2005

Baseline immune dysregulation in autologous stem cell transplant recipients is associated with a 'graft versus host'-like syndrome and poor outcomes

artículo científico publicado en 2020

Bendamustine and rituximab (BR) versus dexamethasone, rituximab, and cyclophosphamide (DRC) in patients with Waldenström macroglobulinemia

artículo científico publicado en 2018

Bendamustine, lenalidomide, and dexamethasone (BRD) is highly effective with durable responses in relapsed multiple myeloma.

artículo científico publicado en 2015

Beta-blockers improve survival outcomes in patients with multiple myeloma: a retrospective evaluation

artículo científico publicado en 2016

BiTEing the Tumor

artículo científico publicado en 2020

Blind men and an elephant

artículo científico publicado en 2015

Blood mass spectrometry detects residual disease better than standard techniques in light-chain amyloidosis

artículo científico publicado en 2020

Bone marrow angiogenesis and circulating plasma cells in multiple myeloma

scientific article published on 01 July 2003

Bone marrow angiogenesis in multiple myeloma: effect of therapy

article

Bone marrow angiogenic ability and expression of angiogenic cytokines in myeloma: evidence favoring loss of marrow angiogenesis inhibitory activity with disease progression.

artículo científico publicado en 2004

Bone marrow plasma cells 20% or greater discriminate presentation, response, and survival in AL amyloidosis

scientific article published on 22 November 2019

Bone microstructural changes revealed by high-resolution peripheral quantitative computed tomography imaging and elevated DKK1 and MIP-1α levels in patients with MGUS.

artículo científico publicado en 2011

Bortezomib mediates antiangiogenesis in multiple myeloma via direct and indirect effects on endothelial cells

artículo científico publicado en 2006

Bortezomib, lenalidomide, and dexamethasone (VRd) followed by autologous stem cell transplant for multiple myeloma

scholarly article by M Hasib Sidiqi et al published 8 November 2018 in Blood Cancer Journal

CRM1 inhibitor anti-tumor activity is enhanced with salicylates by S-phase arrest and impaired DNA-damage repair

artículo científico publicado en 2020

Candidate genes of Waldenström's macroglobulinemia: current evidence and research.

scientific article published on 17 July 2013

Cardiac amyloidosis: a practical approach to diagnosis and management

artículo científico publicado en 2011

Carfilzomib or bortezomib in combination with lenalidomide and dexamethasone for patients with newly diagnosed multiple myeloma without intention for immediate autologous stem-cell transplantation (ENDURANCE): a multicentre, open-label, phase 3, ran

artículo científico publicado en 2020

Cell Trafficking in Multiple Myeloma

artículo científico publicado en 2012

Cell proliferation of myeloma plasma cells: comparison of the blood and marrow compartments

artículo científico publicado en 2004

Challenges in the Management of patients with systemic light chain (AL) amyloidosis during the COVID-19 pandemic

artículo científico publicado en 2020

Changes in serum-free light chain rather than intact monoclonal immunoglobulin levels predicts outcome following therapy in primary amyloidosis

artículo científico publicado en 2011

Changes in uninvolved immunoglobulins during induction therapy for newly diagnosed multiple myeloma

artículo científico publicado en 2017

Characteristics of exceptional responders to autologous stem cell transplantation in multiple myeloma

scientific article published on 28 August 2020

Characteristics of exceptional responders to lenalidomide-based therapy in multiple myeloma.

artículo científico publicado en 2015

Characteristics of late transplant-associated thrombotic microangiopathy (TA-TMA) in patients who underwent allogeneic hematopoietic stem cell transplantation

artículo científico publicado en 2020

Characteristics of long-term survivors with multiple myeloma: A National Cancer Data Base analysis

artículo científico publicado en 2019

Characterization and prognostic implication of delayed complete response in AL amyloidosis

scientific article published on 23 November 2020

Checking in: T cells against multiple myeloma.

artículo científico publicado en 2017

Clarification on the definition of complete haematologic response in light-chain (AL) amyloidosis

artículo científico publicado en 2021

Clarithromycin (Biaxin)-lenalidomide-low-dose dexamethasone (BiRd) versus lenalidomide-low-dose dexamethasone (Rd) for newly diagnosed myeloma

artículo científico publicado en 2010

Clinical Course and Prognosis of Non-Secretory Multiple Myeloma.

artículo científico publicado en 2015

Clinical Features Associated with COVID-19 Outcome in MM: First Results from International Myeloma Society Dataset

artículo científico publicado en 2020

Clinical Features and Treatment Outcomes of Patients With Necrobiotic Xanthogranuloma Associated With Monoclonal Gammopathies.

artículo científico publicado en 2016

Clinical and prognostic differences among patients with light chain deposition disease, myeloma cast nephropathy and both.

artículo científico publicado en 2015

Clinical characteristics and outcomes in biclonal gammopathies

artículo científico publicado en 2016

Clinical characteristics and treatment outcomes of newly diagnosed multiple myeloma with chromosome 1q abnormalities

artículo científico publicado en 2020

Clinical course and prognosis of non-secretory multiple myeloma

artículo científico publicado en 2015

Clinical course of light-chain smouldering multiple myeloma (idiopathic Bence Jones proteinuria): a retrospective cohort study

artículo científico publicado en 2014

Clinical course of patients with relapsed multiple myeloma

artículo científico publicado en 2004

Clinical features and survival outcomes in IgD myeloma: a study by Asia Myeloma Network (AMN)

artículo científico publicado en 2020

Clinical features and treatment response of light chain (AL) amyloidosis diagnosed in patients with previous diagnosis of multiple myeloma ⬇️

artículo científico publicado en 2010

Clinical features of patients with immunoglobulin light chain amyloidosis (AL) with vascular-limited deposition in the kidney

artículo científico publicado en 2011

Clinical features, laboratory characteristics and outcomes of patients with renal versus cardiac light chain amyloidosis

scientific article published on 05 March 2019

Clinical implication of centrosome amplification in plasma cell neoplasm

artículo científico publicado en 2005

Clinical outcome of immunoglobulin light chain amyloidosis affecting the kidney.

artículo científico publicado en 2009

Clinical predictors of long-term survival in newly diagnosed transplant eligible multiple myeloma - an IMWG Research Project

artículo científico publicado en 2018

Clinical presentation and outcomes of patients with type 1 monoclonal cryoglobulinemia

artículo científico publicado en 2017

Clinical use and applications of histone deacetylase inhibitors in multiple myeloma

artículo científico publicado en 2016

Clonal competition with alternating dominance in multiple myeloma.

artículo científico publicado en 2012

Coexistent multiple myeloma or increased bone marrow plasma cells define equally high-risk populations in patients with immunoglobulin light chain amyloidosis

artículo científico publicado en 2013

Coinherited genetics of multiple myeloma and its precursor, monoclonal gammopathy of undetermined significance

scientific article published on 01 June 2020

Colon perforation in multiple myeloma patients - A complication of high-dose steroid treatment

scientific article published on 06 October 2020

Combination of the mTOR inhibitor rapamycin and CC-5013 has synergistic activity in multiple myeloma

artículo científico publicado en 2004

Combination therapy incorporating Bcl-2 inhibition with Venetoclax for the treatment of refractory primary plasma cell leukemia with t (11;14).

artículo científico publicado en 2017

Combination therapy with lenalidomide plus dexamethasone (Rev/Dex) for newly diagnosed myeloma

artículo científico publicado en 2005

Comparable outcomes in nonsecretory and secretory multiple myeloma after autologous stem cell transplantation

artículo científico publicado en 2008

Comparable outcomes using propylene glycol-free melphalan for autologous stem cell transplantation in multiple myeloma.

artículo científico publicado en 2018

Comparative analysis of staging systems in AL amyloidosis

scientific article published on 23 January 2019

Comparison of different techniques to identify cardiac involvement in immunoglobulin light chain (AL) amyloidosis

Conflicts of interest, authorship, and disclosures in industry-related scientific publications

artículo científico publicado en 2010

Consensus Conference on Salvage Hematopoietic Cell Transplantation in Patients with Relapsed Multiple Myeloma (short title)

artículo científico publicado en 2015

Consensus in the Management of Multiple Myeloma in India at Myeloma State of the Art 2016 Conference.

artículo científico publicado en 2017

Consensus recommendations for standard investigative workup: report of the International Myeloma Workshop Consensus Panel 3.

artículo científico publicado en 2011

Convenience, satisfaction, health-related quality of life of once-weekly 70 mg/m2 vs. twice-weekly 27 mg/m2 carfilzomib (randomized A.R.R.O.W. study)

artículo científico publicado en 2019

Correction: Bone marrow plasma cells 20% or greater discriminate presentation, response, and survival in AL amyloidosis

artículo científico publicado en 2020

Correlation between urine ACR and 24-h proteinuria in a real-world cohort of systemic AL amyloidosis patients

artículo científico publicado en 2020

Corrigendum: Genome-wide association study identifies variants at 16p13 associated with survival in multiple myeloma patients

artículo científico publicado en 2015

Cost-effectiveness analysis of a risk-adapted algorithm of plerixafor use for autologous peripheral blood stem cell mobilization

artículo científico publicado en 2012

Cost-effectiveness analysis of early vs. late autologous stem cell transplantation in multiple myeloma

artículo científico publicado en 2014

Current Therapies for Light-Chain Amyloidosis

Cytogenetic Features and Clinical Outcomes of Patients With Non-secretory Multiple Myeloma in the Era of Novel Agent Induction Therapy

artículo científico publicado en 2019

Cytogenetic abnormalities in multiple myeloma: association with disease characteristics and treatment response

artículo científico publicado en 2020

Cytokine and chemokine profiles in multiple myeloma; significance of stromal interaction and correlation of IL-8 production with disease progression

artículo científico publicado en 2006

Daratumumab as successful initial therapy for AL amyloidosis with nerve involvement

artículo científico publicado en 2020

Daratumumab in untreated newly diagnosed multiple myeloma

scientific article published on 23 December 2019

Daratumumab plus Lenalidomide and Dexamethasone for Untreated Myeloma

artículo científico publicado en 2019

Daratumumab-based therapy in patients with heavily-pretreated AL amyloidosis

artículo científico publicado en 2018

Daratumumab-lenalidomide-dexamethasone vs standard-of-care regimens: Efficacy in transplant-ineligible untreated myeloma

scientific article published on 17 August 2020

Defining cure in multiple myeloma: a comparative study of outcomes of young individuals with myeloma and curable hematologic malignancies.

artículo científico publicado en 2018

Delayed neutrophil engraftment in patients receiving Daratumumab as part of their first induction regimen for multiple myeloma

scientific article published on 21 October 2019

Delineation of the timing of second line therapy post- autologous stem cell transplant in patients with AL amyloidosis

artículo científico

Depth of organ response in AL amyloidosis is associated with improved survival: grading the organ response criteria.

artículo científico publicado en 2018

Depth of organ response in AL amyloidosis is associated with improved survival: new proposed organ response criteria

scientific article published on 01 January 2019

Depth of response prior to autologous stem cell transplantation predicts survival in light chain amyloidosis

artículo científico publicado en 2020

Detection and prevalence of monoclonal gammopathy of undetermined significance: a study utilizing mass spectrometry-based monoclonal immunoglobulin rapid accurate mass measurement

scientific article published on 13 December 2019

Development of thrombocytopenia during first-line treatment and survival outcomes in newly diagnosed multiple myeloma

artículo científico publicado en 2019

Dexamethasone, rituximab and cyclophosphamide for relapsed and/or refractory and treatment-naïve patients with Waldenstrom macroglobulinemia

artículo científico

Diagnosis and Management of Waldenström Macroglobulinemia: Mayo Stratification of Macroglobulinemia and Risk-Adapted Therapy (mSMART) Guidelines 2016.

artículo científico publicado en 2017

Diagnosis and management of Waldenström macroglobulinemia: Mayo stratification of macroglobulinemia and risk-adapted therapy (mSMART) guidelines

artículo científico publicado en 2010

Diagnosis and management of smoldering multiple myeloma: the razor's edge between clonality and cancer

artículo científico publicado en 2017

Differences between unselected patients and participants in multiple myeloma clinical trials in US: a threat to external validity

artículo científico publicado en 2016

Differences in engraftment with day-1 compared with day-2 melphalan prior to stem cell infusion in myeloma patients receiving autologous stem cell transplant

artículo científico publicado en 2020

Differences in genomic abnormalities among African individuals with monoclonal gammopathies using calculated ancestry

article

Differences in the distribution of cytogenetic subtypes between multiple myeloma patients with and without a family history of monoclonal gammopathy and multiple myeloma

artículo científico publicado en 2013

Differential expression of vascular endothelial growth factors and their receptors in multiple myeloma.

artículo científico publicado en 2006

Digoxin use in systemic light-chain (AL) amyloidosis: contra-indicated or cautious use?

article by Eli Muchtar et al published 12 March 2018 in Amyloid

Dinaciclib, a novel CDK inhibitor, demonstrates encouraging single-agent activity in patients with relapsed multiple myeloma.

artículo científico publicado en 2014

Discordance between serum cardiac biomarker and immunoglobulin-free light-chain response in patients with immunoglobulin light-chain amyloidosis treated with immune modulatory drugs

artículo científico publicado en 2010

Dose and Schedule Selection of the Oral Proteasome Inhibitor Ixazomib in Relapsed/Refractory Multiple Myeloma: Clinical and Model-Based Analyses

artículo científico

Drug insight: thalidomide as a treatment for multiple myeloma

artículo científico publicado en 2005

Early reduction of serum-free light chains associates with renal recovery in myeloma kidney.

artículo científico publicado en 2011

Early versus delayed autologous transplantation after immunomodulatory agents-based induction therapy in patients with newly diagnosed multiple myeloma.

artículo científico publicado en 2011

Effect of hematologic response on outcome of patients undergoing transplantation for primary amyloidosis: importance of achieving a complete response

artículo científico publicado en 2007

Efficacy and safety of carfilzomib-based regimens in frail patients with relapsed and/or refractory multiple myeloma

artículo científico publicado en 2020

Efficacy of VDT PACE-like regimens in treatment of relapsed/refractory multiple myeloma

artículo científico publicado en 2017

Efficacy of daratumumab-based therapies in patients with relapsed, refractory multiple myeloma treated outside of clinical trials

artículo científico publicado en 2017

Efficacy of retreatment with immunomodulatory drugs (IMiDs) in patients receiving IMiDs for initial therapy of newly diagnosed multiple myeloma

artículo científico publicado en 2011

Efficacy of venetoclax as targeted therapy for relapsed/refractory t(11;14) multiple myeloma

artículo científico publicado en 2017

Elevation of serum lactate dehydrogenase in AL amyloidosis reflects tissue damage and is an adverse prognostic marker in patients not eligible for stem cell transplantation

artículo científico publicado en 2017

Enhancing the R-ISS classification of newly diagnosed multiple myeloma by quantifying circulating clonal plasma cells

artículo científico publicado en 2020

Evaluation of pretransplant factors predicting cardiac dysfunction following high-dose melphalan conditioning and autologous peripheral blood stem cell transplantation

scientific article published on 13 July 2012

Evidence for cytogenetic and fluorescence in situ hybridization risk stratification of newly diagnosed multiple myeloma in the era of novel therapie

artículo científico publicado en 2010

Evolving changes in disease biomarkers and risk of early progression in smoldering multiple myeloma

artículo científico publicado en 2016

Expanded safety experience with lenalidomide plus dexamethasone in relapsed or refractory multiple myeloma

artículo científico publicado en 2009

Expression of CD52 on plasma cells in plasma cell proliferative disorders ⬇️

artículo científico publicado el 24 de abril de 2003

FQPD, a novel immunomodulatory drug, has significant in vitro activity in multiple myeloma

artículo científico publicado en 2006

FTY720 induces apoptosis in multiple myeloma cells and overcomes drug resistance

artículo científico publicado en 2005

Factors associated with favorable outcome after allogeneic hematopoietic stem cell transplantation for multiple myeloma.

artículo científico publicado en 2009

Fifteen year overall survival rates after autologous stem cell transplantation for AL amyloidosis

scientific article published on 11 July 2019

Fifty-Year Incidence of Waldenström Macroglobulinemia in Olmsted County, Minnesota, From 1961 Through 2010: A Population-Based Study With Complete Case Capture and Hematopathologic Review

artículo científico publicado en 2018

Frequent methylation of the tumour suppressor miR-1258 targeting PDL1: implication in multiple myeloma-specific cytotoxicity and prognostification

artículo científico publicado en 2020

Functional interaction of plasmacytoid dendritic cells with multiple myeloma cells: a therapeutic target.

artículo científico publicado en 2009

Gene signature combinations improve prognostic stratification of multiple myeloma patients.

artículo científico publicado en 2015

Genetic variants in DNA repair pathways are not associated with disease progression among multiple myeloma patients

artículo científico publicado en 2013

Genome-wide association study identifies variants at 16p13 associated with survival in multiple myeloma patients.

artículo científico publicado en 2015

Genomic Profiling of Smoldering Multiple Myeloma Identifies Patients at a High Risk of Disease Progression

scientific article published on 22 May 2020

Geriatric assessment predicts survival and toxicities in elderly myeloma patients: an International Myeloma Working Group report

artículo científico publicado en 2015

Glutamine-derived 2-hydroxyglutarate is associated with disease progression in plasma cell malignancies.

artículo científico publicado en 2018

Glycosylation of Immunoglobulin Light Chains is Highly Prevalent in Cold Agglutinin Disease

scientific article published on 01 May 2020

Health-Related Quality of Life after Autologous Stem Cell Transplantation for Multiple Myeloma

scientific article published on 04 April 2018

Health-Related Quality of Life in Transplant-Ineligible Patients With Newly Diagnosed Multiple Myeloma: Findings From the Phase III MAIA Trial

artículo científico publicado en 2020

Hematologic characteristics of proliferative glomerulonephritides with nonorganized monoclonal immunoglobulin deposits

artículo científico

Hematology patient reported symptom screen to assess quality of life for AL amyloidosis

artículo científico publicado en 2017

Hematopoietic cell transplantation utilization and outcomes for primary plasma cell leukemia in the current era

artículo científico publicado en 2020

Hematopoietic recovery kinetics predicts for poor CD34+ cell mobilization after cyclophosphamide chemotherapy in multiple myeloma

scientific article published on 29 September 2011

Hematopoietic score predicts outcomes in newly diagnosed multiple myeloma patients

scientific article published on 29 October 2019

High-Dose Melphalan versus Melphalan plus Dexamethasone for AL Amyloidosis

scientific article published on 01 January 2008

High-dose chemotherapy with autologous hematopoietic stem cell transplantation in patients with multiple myeloma

artículo científico publicado en 2006

High-dose melphalan and autologous hematopoietic stem cell transplant in patient with C3 glomerulonephritis associated with monoclonal gammopathy

High-dose melphalan and peripheral blood stem cell transplantation for light-chain amyloidosis with cardiac involvement

artículo científico publicado en 2011

Histone deacetylase inhibition in combination with MEK or BCL-2 inhibition in multiple myeloma

artículo científico publicado en 2019

Honokiol overcomes conventional drug resistance in human multiple myeloma by induction of caspase-dependent and -independent apoptosis

artículo científico publicado en 2005

Hyperhaploid plasma cell myeloma characterized by poor outcome and monosomy 17 with frequently co-occurring TP53 mutations

article

IAP antagonists induce anti-tumor immunity in multiple myeloma.

artículo científico publicado en 2016

Ibrutinib monotherapy outside of clinical trial setting in Waldenström macroglobulinaemia: practice patterns, toxicities and outcomes

scientific article published on 29 August 2019

Identifying professional education gaps and barriers in multiple myeloma patient care: findings of the Managing Myeloma Continuing Educational Initiative Advisory Committee

artículo científico publicado en 2014

Idiopathic systemic capillary leak syndrome (Clarkson's disease): the Mayo clinic experience

artículo científico publicado en 2010

Idiotype-pulsed antigen-presenting cells following autologous transplantation for multiple myeloma may be associated with prolonged survival

artículo científico publicado en 2009

IgM AL amyloidosis: delineating disease biology and outcomes with clinical, genomic and bone marrow morphological features

scientific article published on 28 November 2019

IgM Monoclonal Gammopathy of Undetermined Significance (MGUS) and Smoldering Waldenström's Macroglobulinemia (SWM)

artículo científico publicado en 2011

Immune Therapies in Multiple Myeloma.

artículo científico publicado en 2016

Immune-based therapies in the management of multiple myeloma

scientific article published on 22 August 2020

Immunoglobulin D amyloidosis: a distinct entity

artículo científico publicado en 2011

Immunoglobulin free light chain ratio is an independent risk factor for progression of smoldering (asymptomatic) multiple myeloma

artículo científico publicado en 2008

Immunoglobulin light chain amyloidosis is diagnosed late in patients with preexisting plasma cell dyscrasias

scientific article published on 02 September 2014

Immunoglobulin m monoclonal gammopathy of undetermined significance and smoldering Waldenström macroglobulinemia

artículo científico publicado en 2013

Immunoparesis in newly diagnosed AL amyloidosis is a marker for response and survival

Immunoparesis status in AL amyloidosis at diagnosis affects response and survival by regimen type

Immunoparesis status in immunoglobulin light chain amyloidosis at diagnosis affects response and survival by regimen type

artículo científico publicado en 2016

Immunophenotyping in multiple myeloma and related plasma cell disorders ⬇️

artículo científico publicado el 1 de septiembre de 2010

Impact of CD138 Magnetic Bead-based Positive Selection on Bone Marrow Plasma Cell Surface Markers

artículo científico publicado en 2020

Impact of MYD88L265P mutation status on histological transformation of Waldenström Macroglobulinemia

scientific article published on 31 December 2019

Impact of Post-Transplant Response and Minimal Residual Disease on Survival in Myeloma with High-Risk Cytogenetics.

artículo científico publicado en 2017

Impact of acquired del(17p) in multiple myeloma

artículo científico publicado en 2019

Impact of concomitant dexamethasone dosing schedule on bortezomib-induced peripheral neuropathy in multiple myeloma.

artículo científico publicado en 2017

Impact of consolidation therapy post autologous stem cell transplant in patients with light chain amyloidosis

scientific article published on 23 July 2019

Impact of dexamethasone responsiveness on long term outcome in patients with newly diagnosed multiple myeloma

artículo científico publicado en 2009

Impact of duration of induction therapy on survival in newly diagnosed multiple myeloma patients undergoing upfront autologous stem cell transplantation.

artículo científico publicado en 2018

Impact of gene expression profiling-based risk stratification in patients with myeloma receiving initial therapy with lenalidomide and dexamethasone

artículo científico publicado en 2011

Impact of high-risk classification by FISH: an eastern cooperative oncology group (ECOG) study E4A03.

artículo científico publicado en 2011

Impact of involved free light chain (FLC) levels in patients achieving normal FLC ratio after initial therapy in light chain amyloidosis (AL).

artículo científico publicado en 2017

Impact of minimal residual negativity using next generation flow cytometry on outcomes in light chain amyloidosis

artículo científico publicado en 2020

Impact of optimal follow-up of monoclonal gammopathy of undetermined significance on early diagnosis and prevention of myeloma-related complications.

artículo científico publicado en 2010

Impact of pre-transplant bone marrow plasma cell percentage on post-transplant response and survival in newly diagnosed multiple myeloma.

artículo científico publicado en 2016

Impact of pretransplant therapy and depth of disease response before autologous transplantation for multiple myeloma

artículo científico publicado en 2014

Impact of prior diagnosis of monoclonal gammopathy on outcomes in newly diagnosed multiple myeloma

scientific article published on 20 February 2019

Impact of prior melphalan exposure on stem cell collection in light chain amyloidosis

artículo científico publicado en 2017

Impact of risk stratification on outcome among patients with multiple myeloma receiving initial therapy with lenalidomide and dexamethasone

artículo científico publicado en 2009

Impact of vitamin D deficiency on the clinical presentation and prognosis of patients with newly diagnosed multiple myeloma

artículo científico publicado en 2009

Implications and outcomes of MRD-negative multiple myeloma patients with immunofixation positivity

scientific article published on 30 December 2019

Implications of MYC Rearrangements in Newly Diagnosed Multiple Myeloma

artículo científico publicado en 2020

Implications of continued response after autologous stem cell transplantation for multiple myeloma

artículo científico publicado en 2013

Implications of detecting serum monoclonal protein by MASS-fix following stem cell transplantation in multiple myeloma

artículo científico publicado en 2020

Importance of achieving stringent complete response after autologous stem-cell transplantation in multiple myeloma

artículo científico publicado en 2013

Improved Outcomes After Autologous Hematopoietic Cell Transplantation for Light Chain Amyloidosis: A Center for International Blood and Marrow Transplant Research Study

artículo científico publicado en 2015

Improved outcomes for newly diagnosed AL amyloidosis between 2000 and 2014: cracking the glass ceiling of early death

artículo científico publicado en 2017

Improved survival in multiple myeloma and the impact of novel therapies

artículo científico publicado en 2007

In vitro and ex vivo gene expression profiling reveals differential kinetic response of HSPs and UPR genes is associated with PI resistance in multiple myeloma

artículo científico publicado en 2020

In vivo and in silico studies on single versus multiple transplants for multiple myeloma.

artículo científico publicado en 2007

Incidence of AL Amyloidosis in Olmsted County, Minnesota, 1990 through 2015

Incidence of monoclonal gammopathy of undetermined significance and estimation of duration before first clinical recognition

artículo científico publicado en 2012

Incidence of supraventricular arrhythmias during autologous peripheral blood stem cell transplantation

artículo científico publicado en 2013

Incidence, clinical course, and prognosis of secondary monoclonal gammopathy of undetermined significance in patients with multiple myeloma

artículo científico publicado en 2011

Increased Bone Marrow Plasma-Cell Percentage Predicts Outcomes in Newly Diagnosed Multiple Myeloma Patients

scientific article published on 07 April 2020

Increased prevalence of light chain monoclonal gammopathy of undetermined significance (LC-MGUS) in first-degree relatives of individuals with multiple myeloma

artículo científico publicado en 2012

Increased risk of monoclonal gammopathy in first-degree relatives of patients with multiple myeloma or monoclonal gammopathy of undetermined significance

artículo científico publicado en 2009

Independent Prognostic Value of Stroke Volume Index in Patients With Immunoglobulin Light Chain Amyloidosis

artículo científico publicado en 2018

Induction of a chronic disease state in patients with smoldering or indolent multiple myeloma by targeting interleukin 1{beta}-induced interleukin 6 production and the myeloma proliferative component

artículo científico publicado en 2009

Induction therapy pre-autologous stem cell transplantation in immunoglobulin light chain amyloidosis: a retrospective evaluation

artículo científico publicado en 2016

Inhibition of histone deacetylase overcomes rapamycin-mediated resistance in diffuse large B-cell lymphoma by inhibiting Akt signaling through mTORC2

artículo científico publicado en 2009

Initial treatment of transplant-eligible patients in multiple myeloma

artículo científico

International Myeloma Working Group consensus criteria for response and minimal residual disease assessment in multiple myeloma

artículo científico publicado en 2016

International Myeloma Working Group risk stratification model for smoldering multiple myeloma (SMM)

artículo científico publicado en 2020

International Myeloma Working Group updated criteria for the diagnosis of multiple myeloma

artículo científico publicado en 2014

International harmonization in performing and reporting minimal residual disease assessment in multiple myeloma trials

artículo científico publicado en 2020

International myeloma working group consensus recommendations on imaging in monoclonal plasma cell disorders

scientific article published on 01 June 2019

Interpreting clinical trial data in multiple myeloma: translating findings to the real-world setting

scientific article published on 09 November 2018

Ixazomib cardiotoxicity: A possible class effect of proteasome inhibitors

scientific article published on 01 February 2017

Ixazomib for the treatment of multiple myeloma

scientific article published on 13 November 2018

Ixazomib maintenance therapy in newly diagnosed multiple myeloma: An integrated analysis of four phase I/II studies

scientific article published on 08 May 2019

Ixazomib significantly prolongs progression-free survival in high-risk relapsed/refractory myeloma patients.

artículo científico publicado en 2017

Ixazomib, lenalidomide, and dexamethasone in patients with newly diagnosed multiple myeloma: long-term follow-up including ixazomib maintenance

artículo científico publicado en 2019

Kinetics of organ response and survival following normalization of the serum free light chain ratio in AL amyloidosis

artículo científico publicado en 2015

Lenalidomide plus dexamethasone versus thalidomide plus dexamethasone in newly diagnosed multiple myeloma: a comparative analysis of 411 patients

artículo científico publicado en 2009

Lenalidomide plus dexamethasone vs. lenalidomide plus melphalan and prednisone: a retrospective study in newly diagnosed elderly myeloma

artículo científico publicado en 2010

Lenalidomide, cyclophosphamide and dexamethasone (CRd) for newly diagnosed multiple myeloma: results from a phase 2 trial

artículo científico publicado en 2011

Lenalidomide, cyclophosphamide, and dexamethasone (CRd) for light-chain amyloidosis: long-term results from a phase 2 trial

artículo científico publicado en 2012

Light chain type predicts organ involvement and survival in AL amyloidosis patients receiving stem cell transplantation

artículo científico publicado en 2018

Limiting early mortality: Do's and don'ts in the management of patients with newly diagnosed multiple myeloma

artículo científico

Long-Term Follow-up of Monoclonal Gammopathy of Undetermined Significance

artículo científico publicado en 2018

Long-term disease control in patients with newly diagnosed multiple myeloma after suspension of lenalidomide therapy

artículo científico publicado en 2014

Long-term outcome of patients with POEMS syndrome: An update of the Mayo Clinic experience

artículo científico publicado en 2016

Long-term outcomes after autologous stem cell transplantation for patients with POEMS syndrome (osteosclerotic myeloma): a single-center experience

artículo científico publicado en 2012

Long-term outcomes of IMiD-based trials in patients with immunoglobulin light-chain amyloidosis: a pooled analysis

artículo científico publicado en 2020

Long-term outcomes of patients with light chain amyloidosis (AL) after renal transplantation with or without stem cell transplantation

artículo científico publicado en 2011

Long-term results of response to therapy, time to progression, and survival with lenalidomide plus dexamethasone in newly diagnosed myeloma

artículo científico publicado en 2007

Long-term results of single-agent thalidomide as initial therapy for asymptomatic (smoldering or indolent) myeloma

artículo científico publicado en 2010

Low levels of interleukin-1 receptor antagonist (IL-1RA) predict engraftment syndrome after autologous stem cell transplantation in POEMS syndrome and other plasma cell neoplasms.

artículo científico publicado en 2013

Lymphoma-like double-hit genetic abnormalities (MYC/IGH and IGH/BCL2) in a case of non-secretory multiple myeloma

scientific article published on 21 September 2020

MYC dysregulation in the progression of multiple myeloma

artículo científico publicado en 2019

MYD88 mutation status does not impact overall survival in Waldenström macroglobulinemia.

artículo científico publicado en 2017

Maintenance versus Induction Therapy Choice on Outcomes after Autologous Transplantation for Multiple Myeloma

artículo científico publicado en 2016

Management of adverse events associated with ixazomib plus lenalidomide/dexamethasone in relapsed/refractory multiple myeloma

artículo científico publicado en 2017

Management of newly diagnosed symptomatic multiple myeloma: updated Mayo Stratification of Myeloma and Risk-Adapted Therapy (mSMART) consensus guidelines

scientific article published on December 2009

Management of newly diagnosed symptomatic multiple myeloma: updated Mayo Stratification of Myeloma and Risk-Adapted Therapy (mSMART) consensus guidelines 2013.

artículo científico

Management of relapsed and refractory multiple myeloma: novel agents, antibodies, immunotherapies and beyond

artículo científico publicado en 2017

Many facets of bortezomib resistance/susceptibility

artículo científico publicado en 2008

Mass cytometry dissects T cell heterogeneity in the immune tumor microenvironment of common dysproteinemias at diagnosis and after first line therapies

scientific article published on 28 August 2019

Mass cytometry identifies expansion of double positive and exhausted T cell subsets in the tumour microenvironment of patients with POEMS syndrome

artículo científico publicado en 2020

Mate pair sequencing outperforms fluorescence in situ hybridization in the genomic characterization of multiple myeloma

scientific article published on 16 December 2019

Mayo clinic consensus statement for the use of bisphosphonates in multiple myeloma

artículo científico publicado en 2006

Mcl-1 as a buffer for proapoptotic Bcl-2 family members during TRAIL-induced apoptosis: a mechanistic basis for sorafenib (Bay 43-9006)-induced TRAIL sensitization.

artículo científico publicado en 2007

Metabolomic and Lipidomic Profiling of Bone Marrow Plasma Differentiates Patients with Monoclonal Gammopathy of Undetermined Significance from Multiple Myeloma

artículo científico publicado en 2020

Metaphase cytogenetics and plasma cell proliferation index for risk stratification in newly diagnosed multiple myeloma

artículo científico publicado en 2020

Microbiota-driven interleukin-17-producing cells and eosinophils synergize to accelerate multiple myeloma progression

scientific article published in Nature Communications

Mobilization in myeloma revisited: IMWG consensus perspectives on stem cell collection following initial therapy with thalidomide-, lenalidomide-, or bortezomib-containing regimens

artículo científico publicado en 2009

Molecular Dissection of Hyperdiploid Multiple Myeloma by Gene Expression Profiling

article

Molecular characterization of PS-341 (bortezomib) resistance: implications for overcoming resistance using lysophosphatidic acid acyltransferase (LPAAT)-beta inhibitors.

artículo científico publicado en 2005

Molecular mechanisms whereby immunomodulatory drugs activate natural killer cells: clinical application.

artículo científico publicado en 2005

Molecular signatures of multiple myeloma progression through single cell RNA-Seq

artículo científico publicado en 2019

Monoclonal Gammopathy of Undetermined Significance: Indications for Prediagnostic Testing, Subsequent Diagnoses, and Follow-up Practice at Mayo Clinic

scientific article published on 01 May 2020

Monoclonal gammopathy of undetermined significance (MGUS) consistently precedes multiple myeloma: a prospective study

artículo científico publicado en 2009

Monoclonal gammopathy plus positive amyloid biopsy does not always equal AL amyloidosis

artículo científico publicado en 2019

Monosomic loss of MIR15A/MIR16-1 is a driver of multiple myeloma proliferation and disease progression

artículo científico publicado en 2020

Multicentric Castleman disease – a single center experience of treatment with a focus on autologous stem cell transplantation

Multiple Myeloma, Version 2.2016: Clinical Practice Guidelines in Oncology

artículo científico publicado en 2015

Multiple Myeloma, Version 3.2017, NCCN Clinical Practice Guidelines in Oncology

artículo científico publicado en 2017

Multiple Myeloma, Version 3.2021, NCCN Clinical Practice Guidelines in Oncology

artículo científico publicado en 2020

Multiple Myeloma: Diagnosis and Treatment.

artículo científico publicado en 2016

Multiple mechanisms contribute to the synergistic anti-myeloma activity of the pan-histone deacetylase inhibitor LBH589 and the rapalog RAD001.

artículo científico publicado en 2014

Multiple myeloma

article

Multiple myeloma current treatment algorithms

artículo científico publicado en 2020

Myelomatous Involvement of the Central Nervous System

artículo científico publicado en 2016

N-glycosylation of monoclonal light chains on routine MASS-FIX testing is a risk factor for MGUS progression

artículo científico publicado en 2020

N-terminal fragment of the type-B natriuretic peptide (NT-proBNP) contributes to a simple new frailty score in patients with newly diagnosed multiple myeloma

artículo científico publicado en 2016

NCCN Guidelines Insights: Multiple Myeloma, Version 1.2020

artículo científico publicado en 2019

NCCN Guidelines Insights: Multiple Myeloma, Version 3.2016.

artículo científico publicado en 2016

NCCN Guidelines Insights: Multiple Myeloma, Version 3.2018.

artículo científico publicado en 2018

NCI First International Workshop on the Biology, Prevention, and Treatment of Relapse after Allogeneic Hematopoietic Stem Cell Transplantation: report from the Committee on the Epidemiology and Natural History of Relapse following Allogeneic Cell Tr

artículo científico publicado en 2010

Natural history of amyloidosis isolated to fat and bone marrow aspirate.

artículo científico publicado en 2016

Natural history of multiple myeloma with de novo del(17p)

scholarly article by Arjun Lakshman et al published 7 March 2019 in Blood Cancer Journal

Natural history of relapsed myeloma, refractory to immunomodulatory drugs and proteasome inhibitors: a multicenter IMWG study

artículo científico publicado en 2017

Neutralizing B-cell activating factor antibody improves survival and inhibits osteoclastogenesis in a severe combined immunodeficient human multiple myeloma model

artículo científico publicado en 2007

New cancers after autotransplantations for multiple myeloma

artículo científico publicado en 2014

New criteria for response to treatment in immunoglobulin light chain amyloidosis based on free light chain measurement and cardiac biomarkers: impact on survival outcomes

artículo científico publicado en 2012

New developments in the management of relapsed/refractory multiple myeloma - the role of ixazomib

artículo científico

New investigational drugs with single-agent activity in multiple myeloma

artículo científico publicado en 2016

Novel inosine monophosphate dehydrogenase inhibitor VX-944 induces apoptosis in multiple myeloma cells primarily via caspase-independent AIF/Endo G pathway

artículo científico publicado en 2005

Novel pedigree analysis implicates DNA repair and chromatin remodeling in multiple myeloma risk.

artículo científico publicado en 2018

Novel prognostic scoring system for autologous hematopoietic cell transplantation in multiple myeloma

artículo científico publicado en 2020

On Appetite and Its Loss ⬇️

artículo científico publicado el 1 de mayo de 2003

Optimizing deep response assessment for AL amyloidosis using involved free light chain level at end of therapy: failure of the serum free light chain ratio

scientific article published on 26 September 2018

Oral Ixazomib, Lenalidomide, and Dexamethasone for Multiple Myeloma

artículo científico publicado en 2016

Outcome after autologous stem cell transplantation for multiple myeloma in patients with preceding plasma cell disorders.

artículo científico publicado en 2008

Outcome of patients with IgD and IgM multiple myeloma undergoing autologous hematopoietic stem cell transplantation: a retrospective CIBMTR study

artículo científico publicado en 2010

Outcome of very young (≤40 years) patients with immunoglobulin light chain (AL) amyloidosis

Outcomes and treatments of patients with immunoglobulin light chain amyloidosis who progress or relapse postautologous stem cell transplant.

artículo científico publicado en 2014

Outcomes of Multiple Myeloma Patients with Del 17p Undergoing Autologous Stem Cell Transplantation

artículo científico publicado en 2020

Outcomes of Patients with Light Chain Amyloidosis Who Had Autologous Stem Cell Transplantation with 3 or More Organs Involved

artículo científico publicado en 2019

Outcomes of patients with POEMS syndrome treated initially with radiation

artículo científico publicado en 2013

Outcomes of patients with multiple myeloma refractory to CD38-targeted monoclonal antibody therapy

scientific article published on 11 March 2019

Outcomes of patients with renal monoclonal immunoglobulin deposition disease

artículo científico publicado en 2016

Outcomes of primary refractory multiple myeloma and the impact of novel therapies

artículo científico publicado en 2015

Outcomes with different administration schedules of Bortezomib in Bortezomib, Lenalidomide and dexamethasone (VRd) as first-line therapy in Multiple Myeloma

scientific article published on 16 December 2020

Outcomes with early response to first-line treatment in patients with newly diagnosed multiple myeloma

artículo científico publicado en 2019

Outcomes with early vs. deferred stem cell transplantation in light chain amyloidosis

artículo científico publicado en 2020

Overall survival of patients with triple-class refractory multiple myeloma treated with selinexor plus dexamethasone versus standard of care in MAMMOTH

scientific article published on 24 September 2020

Overall survival of transplant eligible patients with newly diagnosed multiple myeloma: comparative effectiveness analysis of modern induction regimens on outcome

scholarly article by Ashley R Paquin et al published 11 December 2018 in Blood Cancer Journal

Overuse of organ biopsies in immunoglobulin light chain amyloidosis (AL): the consequence of failure of early recognition

artículo científico publicado en 2017

PI3K/AKT/mTOR pathway in multiple myeloma: from basic biology to clinical promise.

artículo científico publicado en 2018

Peripheral blood biomarkers of early immune reconstitution in newly diagnosed multiple myeloma

scientific article published on 13 December 2018

Peripheral blood stem cell transplant for POEMS syndrome is associated with high rates of engraftment syndrome

artículo científico publicado en 2008

Phase 1 study of sorafenib in combination with bortezomib in patients with advanced malignancies.

scientific article published on 26 July 2013

Phase 1 study of weekly dosing with the investigational oral proteasome inhibitor ixazomib in relapsed/refractory multiple myeloma

artículo científico publicado en 2014

Phase 1/2 trial of ixazomib, cyclophosphamide and dexamethasone in patients with previously untreated symptomatic multiple myeloma

scientific article published on 30 July 2018

Phase 2 study of all-oral ixazomib, cyclophosphamide and low-dose dexamethasone for relapsed/refractory multiple myeloma

artículo científico publicado en 2018

Phase I/II study of melphalan, prednisone and lenalidomide combination for patients with newly diagnosed multiple myeloma who are not candidates for stem cell transplantation

artículo científico publicado en 2015

Phase I/II trial of the oral regimen ixazomib, pomalidomide, and dexamethasone in relapsed/refractory multiple myeloma

artículo científico publicado en 2018

Phase II study of bevacizumab in combination with sorafenib in recurrent glioblastoma (N0776): a north central cancer treatment group trial

artículo científico publicado en 2013

Plasma cell proliferative index is an independent predictor of progression in smoldering multiple myeloma

article published in 2018

Plasma cell proliferative index post-transplant is a powerful predictor of prognosis in myeloma patients failing to achieve a complete response

artículo científico publicado en 2018

Plasma cell proliferative index predicts outcome in immunoglobulin light chain amyloidosis treated with stem cell transplantation.

artículo científico publicado en 2018

Plasma levels of tumour necrosis factor alpha and interleukin-6 predict progression-free survival following thalidomide therapy in patients with previously untreated multiple myeloma

artículo científico publicado en 2003

Polyclonal serum free light chain elevation is associated with increased risk of monoclonal gammopathies

scholarly article by Shaji Kumar et al published 17 May 2019 in Blood Cancer Journal

Pomalidomide (CC4047) plus low-dose dexamethasone as therapy for relapsed multiple myeloma

artículo científico publicado en 2009

Pomalidomide plus low-dose dexamethasone in myeloma refractory to both bortezomib and lenalidomide: comparison of 2 dosing strategies in dual-refractory disease

artículo científico publicado en 2011

Pomalidomide, Bortezomib and Dexamethasone (PVD) for Patients with Relapsed, Lenalidomide Refractory Multiple Myeloma

artículo científico publicado en 2017

Post-Transplant Outcomes in High-Risk Compared with Non-High-Risk Multiple Myeloma: A CIBMTR Analysis

artículo científico publicado en 2016

Prediction of poor mobilization of autologous CD34+ cells with growth factor in multiple myeloma patients: implications for risk-stratification.

artículo científico publicado en 2013

Prediction of survival using absolute lymphocyte count for newly diagnosed patients with multiple myeloma: a retrospective study

artículo científico publicado en 2008

Predictors of early response to initial therapy in patients with newly diagnosed symptomatic multiple myeloma

artículo científico publicado en 2015

Predictors of early treatment failure following initial therapy for systemic immunoglobulin light-chain amyloidosis

artículo científico publicado en 2017

Predictors of symptomatic hyperviscosity in Waldenström macroglobulinemia

scientific article published on 02 October 2018

Presentation and Outcomes of Localized Immunoglobulin Light Chain Amyloidosis: The Mayo Clinic Experience

artículo científico publicado en 2017

Prevalence and risk of progression of light-chain monoclonal gammopathy of undetermined significance: a retrospective population-based cohort study

artículo científico publicado en 2010

Prevalence of myeloma precursor state monoclonal gammopathy of undetermined significance in 12372 individuals 10-49 years old: a population-based study from the National Health and Nutrition Examination Survey.

artículo científico publicado en 2017

Primary systemic amyloidosis in patients with Waldenström macroglobulinemia

artículo científico publicado en 2018

Prognostic Role of Beta-2 Microglobulin in Patients with Light Chain Amyloidosis Treated with Autologous Stem Cell Transplantation

artículo científico publicado en 2020

Prognostic Significance of Holter Monitor Findings in Patients With Light Chain Amyloidosis

scientific article published on 02 February 2019

Prognostic Significance of Stringent Complete Response after Stem Cell Transplantation in Immunoglobulin Light Chain Amyloidosis

artículo científico publicado en 2018

Prognostic Validation of SKY92 and Its Combination With ISS in an Independent Cohort of Patients With Multiple Myeloma

artículo científico publicado en 2017

Prognostic Value of Circulating Plasma Cells in Monoclonal Gammopathy of Undetermined Significance

article

Prognostic factors and outcomes of adults with hemophagocytic lymphohistiocytosis

artículo científico publicado en 2014

Prognostic restaging at the time of second-line therapy in patients with AL amyloidosis

artículo científico publicado en 2019

Prognostic significance of circulating plasma cells by multi-parametric flow cytometry in light chain amyloidosis.

artículo científico publicado en 2018

Prognostic significance of interphase FISH in monoclonal gammopathy of undetermined significance

scientific article published on 30 January 2018

Prognostic value of NT-ProBNP and troponin T in patients with light chain amyloidosis and kidney dysfunction undergoing autologous stem cell transplantation

artículo científico publicado en 2020

Prognostic value of angiogenesis in solitary bone plasmacytoma

artículo científico publicado en 2002

Prognostic value of minimal residual disease and polyclonal plasma cells in myeloma patients achieving a complete response to therapy

artículo científico publicado en 2019

Progression in smoldering Waldenstrom macroglobulinemia: long-term results

artículo científico publicado en 2012

Promiscuous mutations activate the noncanonical NF-kappaB pathway in multiple myeloma.

artículo científico publicado en 2007

Promising efficacy and acceptable safety of venetoclax plus bortezomib and dexamethasone in relapsed/refractory MM.

artículo científico publicado en 2017

Propensity score matching analysis to evaluate the comparative effectiveness of daratumumab versus real-world standard of care therapies for patients with heavily pretreated and refractory multiple myeloma

artículo científico publicado en 2018

Pros and cons of frontline autologous transplant in multiple myeloma: the debate over timing

artículo científico publicado en 2018

Proteasome beta subunit pharmacogenomics: gene resequencing and functional genomics

artículo científico publicado en 2008

Quantification of clonal circulating plasma cells in relapsed multiple myeloma

artículo científico publicado en 2014

R-(-)-gossypol (AT-101) activates programmed cell death in multiple myeloma cells.

artículo científico publicado en 2008

Randomized Trial of Lenalidomide Versus Observation in Smoldering Multiple Myeloma

artículo científico publicado en 2019

Randomized phase 2 trial of ixazomib and dexamethasone in relapsed multiple myeloma not refractory to bortezomib

artículo científico publicado en 2016

Randomized, multicenter, phase 2 study (EVOLUTION) of combinations of bortezomib, dexamethasone, cyclophosphamide, and lenalidomide in previously untreated multiple myeloma

artículo científico publicado en 2012

Rapid assessment of hyperdiploidy in plasma cell disorders using a novel multi-parametric flow cytometry method

scientific article published on 08 January 2019

Recent improvements in survival in primary systemic amyloidosis and the importance of an early mortality risk score

artículo científico publicado en 2011

Recent trends in multiple myeloma incidence and survival by age, race, and ethnicity in the United States

artículo científico publicado en 2017

Recycling therapies for myeloma: The need for prospective trials

artículo científico publicado en 2019

Refining amyloid complete hematological response: quantitative serum free light chains superior to ratio

artículo científico publicado en 2020

Relapse after complete response in newly diagnosed multiple myeloma: implications of duration of response and patterns of relapse

artículo científico publicado en 2018

Relationship Between Depth of Response and Outcome in Multiple Myeloma

scientific article published on 01 November 2007

Reply to Castillo et al.

artículo científico publicado en 2018

Reply to S. Girnius et al.

artículo científico publicado en 2013

Residual serum monoclonal protein predicts progression-free survival in patients with previously untreated multiple myeloma

artículo científico publicado en 2010

Response rate, durability of response, and survival after thalidomide therapy for relapsed multiple myeloma

artículo científico publicado en 2003

Response to 'Evolving M-protein pattern in patients with smoldering multiple myeloma: impact on early progression'

artículo científico publicado en 2018

Response to rituximab in patients with type II cryoglobulinemia

artículo científico publicado en 2006

Responsiveness of cytogenetically discrete human myeloma cell lines to lenalidomide: lack of correlation with cereblon and interferon regulatory factor 4 expression levels

artículo científico publicado en 2013

Retroperitoneal involvement with light chain amyloidosis- case series and literature review

artículo científico publicado en 2020

Revised International Staging System Is Predictive and Prognostic for Early Relapse (<24 months) after Autologous Transplantation for Newly Diagnosed Multiple Myeloma

scientific article published on 21 December 2018

Revised International Staging System for Multiple Myeloma: A Report From International Myeloma Working Group

artículo científico publicado en 2015

Revised diagnostic criteria for plasma cell leukemia: results of a Mayo Clinic study with comparison of outcomes to multiple myeloma

scholarly article by Praful Ravi et al published 15 November 2018 in Blood Cancer Journal

Revised prognostic staging system for light chain amyloidosis incorporating cardiac biomarkers and serum free light chain measurements

artículo científico publicado en 2012

Revisiting complete response in light chain amyloidosis

scientific article published on 26 November 2019

Risk adapted therapy for multiple myeloma: back to basics

artículo científico publicado en 2014

Risk of MGUS in relatives of multiple myeloma cases by clinical and tumor characteristics

artículo científico publicado en 2018

Risk stratification of smoldering multiple myeloma incorporating revised IMWG diagnostic criteria.

artículo científico publicado en 2018

Role of 18F-FDG PET/CT in the diagnosis and management of multiple myeloma and other plasma cell disorders: a consensus statement by the International Myeloma Working Group

artículo científico publicado en 2017

SDX-101, the R-enantiomer of etodolac, induces cytotoxicity, overcomes drug resistance, and enhances the activity of dexamethasone in multiple myeloma

artículo científico publicado en 2005

Safety Outcomes for Autologous Stem Cell Transplant in Multiple Myeloma

artículo científico publicado en 2018

Safety and efficacy of propylene glycol-free melphalan as conditioning in patients with AL amyloidosis undergoing stem cell transplantation

artículo científico publicado en 2018

Safety and tolerability of ixazomib, an oral proteasome inhibitor, in combination with lenalidomide and dexamethasone in patients with previously untreated multiple myeloma: an open-label phase 1/2 study

artículo científico publicado en 2014

Salvage second hematopoietic cell transplantation in myeloma

artículo científico publicado en 2013

Second primary malignancies with lenalidomide therapy for newly diagnosed myeloma: a meta-analysis of individual patient data

artículo científico publicado en 2014

Seliciclib (CYC202 or R-roscovitine), a small-molecule cyclin-dependent kinase inhibitor, mediates activity via down-regulation of Mcl-1 in multiple myeloma

artículo científico publicado en 2005

Serial measurements of circulating plasma cells before and after induction therapy have an independent prognostic impact in patients with multiple myeloma undergoing upfront autologous transplantation

artículo científico publicado en 2017

Serum M-spike and transplant outcome in patients with multiple myeloma.

artículo científico publicado en 2007

Serum free light chain measurements to reduce 24-h urine monitoring in patients with multiple myeloma with measurable urine monoclonal protein

scientific article published on 15 August 2018

Serum immunoglobulin free light chain measurements and heavy chain isotype usage provide insight into disease biology in patients with POEMS syndrome

artículo científico publicado en 2010

Serum immunoglobulin free light-chain measurement in primary amyloidosis: prognostic value and correlations with clinical features

artículo científico publicado en 2010

Serum uric acid: novel prognostic factor in primary systemic amyloidosis

artículo científico publicado en 2008

Severity of Baseline Proteinuria Predicts Renal Response in Immunoglobulin Light Chain-Associated Amyloidosis after Autologous Stem Cell Transplantation

artículo científico publicado en 2007

Should we measure clonal circulating plasma cells in light chain amyloidosis?

Single-cell analysis of targeted transcriptome predicts drug sensitivity of single cells within human myeloma tumors.

artículo científico publicado en 2015

Smac mimetic LCL161 overcomes protective ER stress induced by obatoclax, synergistically causing cell death in multiple myeloma

artículo científico publicado en 2016

Smoldering multiple myeloma requiring treatment: time for a new definition?

artículo científico publicado en 2013

Soluble suppression of tumorigenicity 2 (sST2), but not galactin-3, adds to prognostication in patients with systemic AL amyloidosis independent of NT-proBNP and troponin T.

artículo científico publicado en 2015

Sorafenib, a multikinase inhibitor, is effective in vitro against non-Hodgkin lymphoma and synergizes with the mTOR inhibitor rapamycin.

artículo científico publicado en 2011

Staging Systems for Newly Diagnosed Myeloma Patients undergoing Autologous Hematopoietic Cell Transplant: The Revised International Staging System shows the most Differentiation between Groups

article

Staging systems use for risk stratification of systemic amyloidosis in the era of high-sensitivity troponin T assay

artículo científico publicado en 2018

Stem Cell Transplantation for Light Chain Amyloidosis: Decreased Early Mortality Over Time.

artículo científico publicado en 2018

Stem cell transplantation compared with melphalan plus dexamethasone in the treatment of immunoglobulin light-chain amyloidosis

artículo científico publicado en 2016

Stem cell transplantation in multiple myeloma: impact of response failure with thalidomide or lenalidomide induction

artículo científico publicado en 2010

Stem-cell transplantation in multiple myeloma: how far have we come?

scientific article published on 14 November 2019

Substratification of patients with newly diagnosed standard-risk multiple myeloma

scientific article published on 15 February 2019

Successful treatment of scleromyxedema with autologous peripheral blood stem cell transplantation

artículo científico publicado en 2005

Surrogate endpoints in randomised controlled trials: a reality check

artículo científico publicado en 2019

Systemic Immunoglobulin Light Chain Amyloidosis-Associated Myopathy: Presentation, Diagnostic Pitfalls, and Outcome

artículo científico publicado en 2016

Systemic amyloidosis associated with chronic lymphocytic leukemia/small lymphocytic lymphoma

artículo científico publicado en 2013

Systemic amyloidosis from A (AA) to T (ATTR): a review

scientific article published on 14 September 2020

Targeting BCL-2 with venetoclax and dexamethasone in patients with relapsed/refractory t(11;14) multiple myeloma

artículo científico publicado en 2020

Ten-year survival after autologous stem cell transplantation for immunoglobulin light chain amyloidosis

artículo científico publicado en 2012

Ten-year survivors in AL amyloidosis: characteristics and treatment pattern

scientific article published on 12 July 2019

Tetraploidy is associated with poor prognosis at diagnosis in multiple myeloma

scientific article published on 06 February 2019

Thalidomid: current role in the treatment of non-plasma cell malignancies.

artículo científico publicado en 2004

Thalidomide and dexamethasone: therapy for multiple myeloma.

artículo científico publicado en 2005

Thalidomide and lenalidomide in the treatment of multiple myeloma

artículo científico publicado en 2006

The CCND1 c.870G risk allele is enriched in individuals of African ancestry with plasma cell dyscrasias

artículo científico publicado en 2020

The Molecular Analysis for Therapy Choice (NCI-MATCH) Trial: Lessons for Genomic Trial Design

artículo científico publicado en 2020

The Role of Minimal Residual Disease Testing in Myeloma Treatment Selection and Drug Development: Current Value and Future Applications

artículo científico publicado en 2017

The activity of lenalidomide with or without dexamethasone in patients with primary systemic amyloidosis

artículo científico publicado en 2006

The clinical significance of cereblon expression in multiple myeloma

artículo científico publicado en 2013

The first-in-human study of the pan-PIM kinase inhibitor PIM447 in patients with relapsed and/or refractory multiple myeloma

scientific article published on 15 May 2019

The future of myeloma precision medicine: integrating the compendium of known drug resistance mechanisms with emerging tumor profiling technologies

artículo científico publicado en 2019

The impact of dialysis on the survival of patients with immunoglobulin light chain (AL) amyloidosis undergoing autologous stem cell transplantation

artículo científico publicado en 2015

The impact of induction regimen on transplant outcome in newly diagnosed multiple myeloma in the era of novel agents.

artículo científico publicado en 2016

The impact of re-induction prior to salvage autologous stem cell transplantation in multiple myeloma

artículo científico publicado en 2019

The importance of bone marrow examination in determining complete response to therapy in patients with multiple myeloma

scientific article published on 29 July 2009

The importance of bone marrow examination in patients with light chain amyloidosis achieving a complete response

scientific article published on 30 January 2018

The investigational proteasome inhibitor ixazomib for the treatment of multiple myeloma.

artículo científico

The multiple myelomas - current concepts in cytogenetic classification and therapy.

artículo científico publicado en 2018

The prognostic significance of CD45 expression by clonal bone marrow plasma cells in patients with newly diagnosed multiple myeloma

artículo científico publicado en 2016

The prognostic significance of polyclonal bone marrow plasma cells in patients with relapsing multiple myeloma

artículo científico publicado en 2017

The prognostic value of multiparametric flow cytometry in AL amyloidosis at diagnosis and at the end of first-line treatment

artículo científico publicado en 2016

The role of bone marrow biopsy in patients with plasma cell disorders: should all patients with a monoclonal protein be biopsied?

scientific article published on 06 May 2020

The significance of monoclonal gammopathy of undetermined significance

artículo científico publicado en 2009

The small-molecule VEGF receptor inhibitor pazopanib (GW786034B) targets both tumor and endothelial cells in multiple myeloma

artículo científico publicado en 2006

The stepchild in myeloma treatments: is allogeneic transplantation not so bad after all?

scholarly article by Antonia M S Müller et al published February 2019 in Haematologica

The utility of plasma vascular endothelial growth factor levels in the diagnosis and follow-up of patients with POEMS syndrome

scientific article published on 31 August 2011

Therapy for Relapsed Multiple Myeloma: Guidelines From the Mayo Stratification for Myeloma and Risk-Adapted Therapy

artículo científico publicado en 2017

Therapy-related myelodysplastic syndrome/acute leukemia after multiple myeloma in the era of novel agents

article

Time to plateau as a predictor of survival in newly diagnosed multiple myeloma.

artículo científico publicado en 2018

Timing of treatment of smoldering myeloma: delay until progression

scientific article published on 01 November 2018

Translocation t(11;14) and survival of patients with light chain (AL) amyloidosis.

artículo científico publicado en 2009

Transplantation for amyloidosis

artículo científico publicado en 2007

Treating Multiple Myeloma Patients With Oral Therapies

artículo científico publicado en 2017

Treatment approaches and outcomes in plasmacytomas: analysis using a national dataset.

artículo científico publicado en 2018

Treatment for high-risk smoldering myeloma

artículo científico publicado en 2013

Treatment of Immunoglobulin Light Chain Amyloidosis: Mayo Stratification of Myeloma and Risk-Adapted Therapy (mSMART) Consensus Statement

artículo científico

Treatment of Multiple Myeloma: ASCO and CCO Joint Clinical Practice Guideline

artículo científico publicado en 2019

Treatment of newly diagnosed multiple myeloma based on Mayo Stratification of Myeloma and Risk-adapted Therapy (mSMART): consensus statement

artículo científico publicado en 2007

Treatment outcomes of triple class refractory multiple myeloma: a benchmark for new therapies

artículo científico publicado en 2021

Treatment patterns and outcome following initial relapse or refractory disease in patients with systemic light chain amyloidosis

artículo científico publicado en 2017

Treatment trade-offs in myeloma: A survey of consecutive patients about contemporary maintenance strategies

artículo científico publicado en 2013

Treatments for newly diagnosed multiple myeloma: when endurance is interrupted - Authors' reply

artículo científico publicado en 2020

Trends and outcomes in allogeneic hematopoietic stem cell transplant for multiple myeloma at Mayo Clinic

artículo científico

Trends and outcomes of modern staging of solitary plasmacytoma of bone

artículo científico publicado en 2012

Trends in allogeneic stem cell transplantation for multiple myeloma: a CIBMTR analysis

artículo científico publicado en 2011

Trends in survival of patients with primary plasma cell leukemia: a population-based analysis

artículo científico publicado en 2014

Trends in utilization and outcomes of autologous transplantation as early therapy for multiple myeloma

artículo científico publicado en 2013

Trisomies in multiple myeloma: impact on survival in patients with high-risk cytogenetics

artículo científico publicado en 2012

Troponin T level as an exclusion criterion for stem cell transplantation in light-chain amyloidosis.

artículo científico publicado en 2008

Tumor-associated macrophages infiltrate plasmacytomas and can serve as cell carriers for oncolytic measles virotherapy of disseminated myeloma

artículo científico publicado en 2009

Upgraded Standardized Minimal Residual Disease Detection by Next-Generation Sequencing in Multiple Myeloma

artículo científico publicado en 2020

Urinary albumin excretion patterns of patients with cast nephropathy and other monoclonal gammopathy-related kidney diseases

artículo científico publicado en 2012

Use of Beta Blockers is Associated with Survival Outcome of Multiple Myeloma Patients Treated with Pomalidomide

artículo científico publicado en 2020

Use of nonclonal serum immunoglobulin free light chains to predict overall survival in the general population

artículo científico publicado en 2012

Utility and prognostic value of 18 F-FDG positron emission tomography-computed tomography scans in patients with newly diagnosed multiple myeloma

artículo científico publicado en 2018

Utility of repeating bone marrow biopsy for confirmation of complete response in multiple myeloma

artículo científico publicado en 2020

Utility of serum free light chain ratio in response definition in patients with multiple myeloma

artículo científico publicado en 2020

Utilization of hematopoietic stem cell transplantation for the treatment of multiple myeloma: a Mayo Stratification of Myeloma and Risk-Adapted Therapy (mSMART) consensus statement.

artículo científico publicado en 2019

Utilizing multiparametric flow cytometry in the diagnosis of patients with primary plasma cell leukemia

artículo científico publicado en 2020

VEGF induces Mcl-1 up-regulation and protects multiple myeloma cells against apoptosis

artículo científico publicado en 2004

Validation of Mayo Clinic Staging System for Light Chain Amyloidosis With High-Sensitivity Troponin

scientific article published on 15 November 2018

Venetoclax for the treatment of translocation (11;14) AL amyloidosis

scientific article published on 11 May 2020

Venetoclax or placebo in combination with bortezomib and dexamethasone in patients with relapsed or refractory multiple myeloma (BELLINI): a randomised, double-blind, multicentre, phase 3 trial

artículo científico publicado en 2020

Venous thromboembolism risk with contemporary lenalidomide-based regimens despite thromboprophylaxis in multiple myeloma: A systematic review and meta-analysis

scientific article published on 08 January 2020

Whole-exome sequencing of cell-free DNA and circulating tumor cells in multiple myeloma.

artículo científico publicado en 2018

c-MYC expression and maturity phenotypes are associated with outcome benefit from addition of ixazomib to lenalidomide-dexamethasone in myeloma

scientific article published on 07 March 2020

secDrug: a pipeline to discover novel drug combinations to kill drug-resistant multiple myeloma cells using a greedy set cover algorithm and single-cell multi-omics

artículo científico publicado en 2022

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