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A novel role for histone deacetylase 6 in the regulation of the tolerogenic STAT3/IL-10 pathway in APCs.

artículo científico publicado en 2014

Author Correction: Selective HDAC6 inhibitors improve anti-PD-1 immune checkpoint blockade therapy by decreasing the anti-inflammatory phenotype of macrophages and down-regulation of immunosuppressive proteins in tumor cells

scientific article published on 10 October 2019

Bone-specific transcription factor Runx2 interacts with the 1alpha,25-dihydroxyvitamin D3 receptor to up-regulate rat osteocalcin gene expression in osteoblastic cells

scientific journal article

Chromatin remodeling and transcriptional activity of the bone-specific osteocalcin gene require CCAAT/enhancer-binding protein beta-dependent recruitment of SWI/SNF activity

artículo científico publicado en 2006

Discovery of a New Isoxazole-3-hydroxamate-Based Histone Deacetylase 6 Inhibitor SS-208 with Antitumor Activity in Syngeneic Melanoma Mouse Models

artículo científico publicado en 2019

Divergent roles of histone deacetylase 6 (HDAC6) and histone deacetylase 11 (HDAC11) on the transcriptional regulation of IL10 in antigen presenting cells

artículo científico publicado en 2014

Epigenetic regulation of a brain-specific glycosyltransferase N-acetylglucosaminyltransferase-IX (GnT-IX) by specific chromatin modifiers.

artículo científico publicado en 2014

Epigenetic silencing of retinoblastoma gene regulates pathologic differentiation of myeloid cells in cancer.

artículo científico publicado en 2013

Epigenetic therapy for ovarian cancer: promise and progress

artículo científico publicado en 2019

Erratum to: Functional Analysis of Histone Deacetylase 11 (HDAC11)

artículo científico publicado en 2016

Essential role for histone deacetylase 11 (HDAC11) in neutrophil biology.

artículo científico publicado en 2017

Expression and Function of Histone Deacetylase 10 (HDAC10) in B Cell Malignancies

artículo científico publicado en 2016

Functional Analysis of HDACs in Tumorigenesis

scientific article published on 01 January 2019

Functional Analysis of Histone Deacetylase 11 (HDAC11).

artículo científico publicado en 2016

HDAC Inhibition Upregulates PD-1 Ligands in Melanoma and Augments Immunotherapy with PD-1 Blockade.

artículo científico publicado en 2015

HDAC6 plays a non-canonical role in the regulation of anti-tumor immune responses, dissemination, and invasiveness of breast cancer

scientific article published on 30 June 2020

Histone deacetylase 11: A novel epigenetic regulator of myeloid derived suppressor cell expansion and function

artículo científico publicado en 2014

Immunoepigenetics Combination Therapies: An Overview of the Role of HDACs in Cancer Immunotherapy.

artículo científico publicado en 2019

Indocyanine Green-Nexturastat A-PLGA Nanoparticles Combine Photothermal and Epigenetic Therapy for Melanoma

scientific article published on 17 January 2020

Modulation of antigen‐presenting cells by HDAC inhibitors: implications in autoimmunity and cancer

artículo científico publicado el 22 de noviembre de 2011

Phase I trial of histone deacetylase inhibitor panobinostat in addition to glucocorticoids for primary therapy of acute graft-versus-host disease

artículo científico publicado en 2018

Preparation and Biochemical Analysis of Classical Histone Deacetylases.

artículo científico publicado en 2016

Reduced CpG methylation is associated with transcriptional activation of the bone-specific rat osteocalcin gene in osteoblasts

artículo científico publicado en 2002

Regulation of the bone-specific osteocalcin gene by p300 requires Runx2/Cbfa1 and the vitamin D3 receptor but not p300 intrinsic histone acetyltransferase activity

scientific journal article

SWI/SNF-independent nuclease hypersensitivity and an increased level of histone acetylation at the P1 promoter accompany active transcription of the bone master gene Runx2.

scientific article published on August 2009

Selective HDAC6 inhibitors improve anti-PD-1 immune checkpoint blockade therapy by decreasing the anti-inflammatory phenotype of macrophages and down-regulation of immunosuppressive proteins in tumor cells

artículo científico publicado en 2019

Selective histone deacetylase 6 inhibitors bearing substituted urea linkers inhibit melanoma cell growth.

artículo científico publicado en 2012

Silencing of HDAC6 as a therapeutic target in chronic lymphocytic leukemia

artículo científico publicado en 2018

Synthesis and Pharmacological Evaluation of Selective Histone Deacetylase 6 Inhibitors in Melanoma Models

artículo científico publicado en 2017

T cells lacking HDAC11 have increased effector functions and mediate enhanced alloreactivity in a murine model.

artículo científico publicado en 2017

Targeting histone deacetylase 6 mediates a dual anti-melanoma effect: Enhanced antitumor immunity and impaired cell proliferation.

artículo científico publicado en 2015

Tet-Mediated DNA Demethylation Is Required for SWI/SNF-Dependent Chromatin Remodeling and Histone-Modifying Activities That Trigger Expression of the Sp7 Osteoblast Master Gene during Mesenchymal Lineage Commitment.

artículo científico publicado en 2017

The antimelanoma activity of the histone deacetylase inhibitor panobinostat (LBH589) is mediated by direct tumor cytotoxicity and increased tumor immunogenicity.

artículo científico publicado en 2013

c-Abl stabilizes HDAC2 levels by tyrosine phosphorylation repressing neuronal gene expression in Alzheimer's disease

artículo científico publicado en 2014