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Cooperative effects of drug-resistance mutations in the flap region of HIV-1 protease

artículo científico publicado en 2012

Correction to Structural Adaptation of Darunavir Analogues against Primary Mutations in HIV-1 Protease

scientific article published on 16 April 2019

Crystal structure of APOBEC3A bound to single-stranded DNA reveals structural basis for cytidine deamination and specificity

artículo científico publicado en 2017

Deciphering Complex Mechanisms of Resistance and Loss of Potency through Coupled Molecular Dynamics and Machine Learning

artículo científico publicado en 2021

Dengue Protease Substrate Recognition: Binding of the Prime Side

artículo científico publicado en 2016

Dengue Virus NS2B/NS3 Protease Inhibitors Exploiting the Prime Side

artículo científico publicado en 2017

Differential Flap Dynamics in Wild-type and a Drug Resistant Variant of HIV-1 Protease Revealed by Molecular Dynamics and NMR Relaxation.

artículo científico publicado en 2012

Drug Design Strategies to Avoid Resistance in Direct-Acting Antivirals and Beyond

artículo científico publicado en 2021

Drug Resistance Mutations Alter Dynamics of Inhibitor-Bound HIV-1 Protease.

artículo científico publicado en 2014

Effect of black mulberry (Morus nigra) extract treatment on cognitive impairment and oxidative stress status of D-galactose-induced aging mice.

artículo científico publicado en 2015

Elucidating the Interdependence of Drug Resistance from Combinations of Mutations

artículo científico publicado en 2017

HIV-1 Protease Inhibitors Incorporating Stereochemically Defined P2' Ligands To Optimize Hydrogen Bonding in the Substrate Envelope

artículo científico publicado en 2019

Hydration Structure and Dynamics of Inhibitor-Bound HIV-1 Protease.

artículo científico publicado en 2018

Improving Viral Protease Inhibitors to Counter Drug Resistance

artículo científico publicado en 2016

Inhibiting HTLV-1 Protease: A Viable Antiviral Target

artículo científico publicado en 2021

Interdependence of Inhibitor Recognition in HIV-1 Protease.

artículo científico publicado en 2017

Mavyret: A Pan-Genotypic Combination Therapy for the Treatment of Hepatitis C InfectionPublished as part of the Biochemistry series "Biochemistry to Bedside".

artículo científico publicado en 2017

Molecular Determinants of Epistasis in HIV-1 Protease: Elucidating the Interdependence of L89V and L90M Mutations in Resistance

artículo científico publicado en 2019

Molecular and Dynamic Mechanism Underlying Drug Resistance in Genotype 3 Hepatitis C NS3/4A Protease

artículo científico publicado en 2016

Molecular and Structural Mechanism of Pan-Genotypic HCV NS3/4A Protease Inhibition by Glecaprevir

artículo científico publicado en 2020

NMR and MD studies combined to elucidate inhibitor and water interactions of HIV-1 protease and their modulations with resistance mutations

scientific article published on 26 June 2019

Pan-3C Protease Inhibitor Rupintrivir Binds SARS-CoV-2 Main Protease in a Unique Binding Mode

artículo científico publicado en 2021

Phytoplankton Composition and Water Quality of Kamil Abduş Lagoon (Tuzla Lake), Istanbul-Turkey

article

Picomolar to Micromolar: Elucidating the Role of Distal Mutations in HIV-1 Protease in Conferring Drug Resistance

scientific article published on 13 August 2019

Probing Structural Changes among Analogous Inhibitor-Bound Forms of HIV-1 Protease and a Drug-Resistant Mutant in Solution by Nuclear Magnetic Resonance.

artículo científico publicado en 2018

Structural Adaptation of Darunavir Analogues against Primary Mutations in HIV-1 Protease

scientific article published on 31 December 2018

Structural and Thermodynamic Basis of Amprenavir/Darunavir and Atazanavir Resistance in HIV-1 Protease with Mutations at Residue 50

artículo científico publicado en 2013

Structural and Thermodynamic Effects of Macrocyclization in HCV NS3/4A Inhibitor MK-5172

artículo científico publicado en 2016

Structural and molecular analysis of a protective epitope of Lyme disease antigen OspA and antibody interactions

artículo científico publicado en 2016

Structural basis and distal effects of Gag substrate coevolution in drug resistance to HIV-1 protease

artículo científico publicado en 2014

Substrate Envelope-Designed Potent HIV-1 Protease Inhibitors to Avoid Drug Resistance

artículo científico publicado en 2013

Substrate sequence selectivity of APOBEC3A implicates intra-DNA interactions.

artículo científico publicado en 2018

T cell epitope engineering: an avian H7N9 influenza vaccine strategy for pandemic preparedness and response

scholarly article by Leonard Moise et al published 17 July 2018 in Human Vaccines & Immunotherapeutics

Target-Specific Prediction of Ligand Affinity with Structure-Based Interaction Fingerprints

artículo científico publicado en 2019