Lista de obras -

A Potent Germline-like Human Monoclonal Antibody Targets a pH-Sensitive Epitope on H7N9 Influenza Hemagglutinin.

artículo científico publicado en 2017

A Route to Novel Functional Metalloproteins via Hybrids of Cytochrome P450 and Cytochrome c ⬇️

artículo científico publicado el 3 de febrero de 2011

A Single Dose of Anti-HBsAg Antibody-Encoding mRNA-LNPs Suppressed HBsAg Expression: a Potential Cure of Chronic Hepatitis B Virus Infection

artículo científico publicado en 2022

A Unique Human Immunoglobulin Heavy Chain Variable Domain-Only CD33 CAR for the Treatment of Acute Myeloid Leukemia

artículo científico publicado en 2018

A broadly neutralizing germline-like human monoclonal antibody against dengue virus envelope domain III

artículo científico publicado en 2019

A defucosylated bispecific multivalent molecule exhibits broad HIV-1-neutralizing activity and enhanced antibody-dependent cellular cytotoxicity against reactivated HIV-1 latently infected cells

article

A native-like bispecific antibody suppresses the inflammatory cytokine response by simultaneously neutralizing tumor necrosis factor-alpha and interleukin-17A.

artículo científico publicado en 2017

A novel coronavirus (2019-nCoV) causing pneumonia-associated respiratory syndrome

artículo científico publicado en 2020

A novel insight into the heme and NO/CO binding mechanism of the alpha subunit of human soluble guanylate cyclase ⬇️

artículo científico publicado el 2 de julio de 2011

A systems approach to HIV-1 vaccines.

artículo científico publicado en 2016

An immunogen containing four tandem 10E8 epitope repeats with exposed key residues induces antibodies that neutralize HIV-1 and activates an ADCC reporter gene

artículo científico publicado en 2016

Antibody-based candidate therapeutics against HIV-1: implications for virus eradication and vaccine design.

artículo científico publicado en 2013

Bispecific Engineered Antibody Domains (Nanoantibodies) That Interact Noncompetitively with an HIV-1 Neutralizing Epitope and FcRn ⬇️

artículo científico publicado el 7 de agosto de 2012

Conformational Toggling of Yeast Iso-1-Cytochrome c in the Oxidized and Reduced States ⬇️

artículo científico publicado el 8 de noviembre de 2011

Development of Small-Molecule Inhibitors Against Zika Virus Infection

artículo científico publicado en 2019

Development of Small-Molecule MERS-CoV Inhibitors

article

Development of human neutralizing monoclonal antibodies for prevention and therapy of MERS-CoV infections

artículo científico publicado en 2014

Development of small-molecule inhibitors against hantaviruses

artículo científico publicado en 2020

Development of therapeutics for treatment of Ebola virus infection.

artículo científico publicado en 2014

Discovery of T-Cell Infection and Apoptosis by Middle East Respiratory Syndrome Coronavirus

artículo científico publicado en 2015

Discovery of novel candidate therapeutics and diagnostics based on engineered human antibody domains.

artículo científico publicado en 2014

Editorial: Antibody Fc Engineering: Towards Better Therapeutics

artículo científico publicado en 2018

Efficacy of antibody-based therapies against Middle East respiratory syndrome coronavirus (MERS-CoV) in common marmosets.

artículo científico publicado en 2017

Engineered Fc based antibody domains and fragments as novel scaffolds

artículo científico publicado en 2014

Engineered Soluble Monomeric IgG1 Fc with Significantly Decreased Non-Specific Binding.

artículo científico publicado en 2017

Engineered antibody domains with significantly increased transcytosis and half-life in macaques mediated by FcRn

artículo científico publicado en 2015

Engineered soluble monomeric IgG1 CH3 domain: generation, mechanisms of function, and implications for design of biological therapeutics.

artículo científico publicado en 2013

Engineering a Novel Antibody-Peptide Bispecific Fusion Protein Against MERS-CoV

artículo científico publicado en 2019

Escape from humoral immunity is associated with treatment failure in HIV-1-infected patients receiving long-term antiretroviral therapy.

artículo científico publicado en 2017

Establishment of Novel Monoclonal Fabs Specific for Epstein-Barr Virus Encoded Latent Membrane Protein 1

scientific article published on 04 April 2019

Evaluation of antiviral - passive - active immunization ("sandwich") therapeutic strategy for functional cure of chronic hepatitis B in mice

artículo científico publicado en 2019

Exceptionally potent and broadly cross-reactive, bispecific multivalent HIV-1 inhibitors based on single human CD4 and antibody domains.

artículo científico publicado en 2013

Exceptionally potent neutralization of Middle East respiratory syndrome coronavirus by human monoclonal antibodies.

artículo científico publicado en 2014

Fc Engineering: Tailored Synthetic Human IgG1-Fc Repertoire for High-Affinity Interaction with FcRn at pH 6.0

artículo científico publicado en 2018

From therapeutic antibodies to chimeric antigen receptors (CARs): making better CARs based on antigen-binding domain.

artículo científico publicado en 2016

Fucoidan Extracted from the New Zealand -Physicochemical Comparison against Five Other Fucoidans: Unique Low Molecular Weight Fraction Bioactivity in Breast Cancer Cell Lines

article

Functional mapping of B-cell linear epitopes of SARS-CoV-2 in COVID-19 convalescent population

scientific article published on 26 August 2020

Fusion mechanism of 2019-nCoV and fusion inhibitors targeting HR1 domain in spike protein

scientific article published on 11 February 2020

Germlining of the HIV-1 broadly neutralizing antibody domain m36

artículo científico publicado en 2015

Human monoclonal antibodies as candidate therapeutics against emerging viruses

artículo científico publicado en 2017

Immune Repertoire Diversity Correlated with Mortality in Avian Influenza A (H7N9) Virus Infected Patients.

artículo científico publicado en 2016

Improving the CH1-CK heterodimerization and pharmacokinetics of 4Dm2m, a novel potent CD4-antibody fusion protein against HIV-1.

artículo científico publicado en 2016

Interactions of IgG1 CH2 and CH3 Domains with FcRn

scientific article published on 02 April 2014

Investigation of Different Molecular Weight Fucoidan Fractions Derived from New Zealand in Combination with GroA Therapy in Prostate Cancer Cell Lines

article

Junctional and allele-specific residues are critical for MERS-CoV neutralization by an exceptionally potent germline-like antibody.

artículo científico publicado en 2015

Linear epitopes of SARS-CoV-2 spike protein elicit neutralizing antibodies in COVID-19 patients

artículo científico publicado en 2020

Manganese superoxide dismutase from human pathogen Clostridium difficile.

artículo científico publicado en 2015

Middle East respiratory syndrome coronavirus (MERS-CoV) entry inhibitors targeting spike protein.

artículo científico publicado en 2014

Monomeric IgG1 Fc molecules displaying unique Fc receptor interactions that are exploitable to treat inflammation-mediated diseases.

artículo científico publicado en 2014

N-Butanol Subfraction of Brassica Rapa L. Promotes Reactive Oxygen Species Production and Induces Apoptosis of A549 Lung Adenocarcinoma Cells via Mitochondria-Dependent Pathway.

artículo científico publicado en 2018

N-terminal truncation of an isolated human IgG1 CH2 domain significantly increases its stability and aggregation resistance

artículo científico publicado en 2013

Neutralization of Zika virus by germline-like human monoclonal antibodies targeting cryptic epitopes on envelope domain III.

artículo científico publicado en 2017

New Directions for Half-Life Extension of Protein Therapeutics: The Rise of Antibody Fc Domains and Fragments.

artículo científico publicado en 2016

No evidence for a superior platform to develop therapeutic antibodies rapidly in response to MERS-CoV and other emerging viruses.

artículo científico publicado en 2015

One-domain CD4 Fused to Human Anti-CD16 Antibody Domain Mediates Effective Killing of HIV-1-Infected Cells.

artículo científico publicado en 2017

Passive Transfer of A Germline-like Neutralizing Human Monoclonal Antibody Protects Transgenic Mice Against Lethal Middle East Respiratory Syndrome Coronavirus Infection

scientific article published on 19 August 2016

Pharmacodynamics of long-acting folic acid-receptor targeted ritonavir-boosted atazanavir nanoformulations

artículo científico publicado en 2014

Potent In Vivo NK Cell-mediated Elimination of HIV-1-Infected Cells Mobilized by a gp120-bispecific and Hexavalent Broadly Neutralizing Fusion Protein.

artículo científico publicado en 2017

Potent binding of 2019 novel coronavirus spike protein by a SARS coronavirus-specific human monoclonal antibody

artículo científico publicado en 2020

Potential Nutraceutical Use of Tribulus terrestris L. in Human Health

artículo científico publicado en 2022

Precision immunomedicine

artículo científico publicado en 2017

Preparation, Characterization, and Immuno-Enhancing Activity of Polysaccharides from Glycyrrhiza uralensis

artículo científico publicado en 2020

Probing the role of the bridging C509 between the [Fe4S4] cubane and the [NipNid] centre in the A-cluster of acetyl-coenzyme A synthase ⬇️

artículo científico publicado el 22 de noviembre de 2010

Prophylaxis With a Middle East Respiratory Syndrome Coronavirus (MERS-CoV)-Specific Human Monoclonal Antibody Protects Rabbits From MERS-CoV Infection

artículo científico publicado en 2016

Purification, characterization and bioactivities of polysaccharides from Pleurotus ferulae.

artículo científico publicado en 2017

Rapid Elimination of Broadly Neutralizing Antibodies Correlates with Treatment Failure in the Acute Phase of Simian-Human Immunodeficiency Virus Infection

artículo científico publicado en 2019

Recent Progress on Neutralizing Antibodies against Hepatitis B Virus and its Implications

artículo científico publicado en 2019

Recent advances in developing small-molecule inhibitors against SARS-CoV-2

artículo científico publicado en 2021

Receptor-binding domain-specific human neutralizing monoclonal antibodies against SARS-CoV and SARS-CoV-2

artículo científico publicado en 2020

Soluble Monomeric IgG1 Fc ⬇️

artículo científico publicado el 19 de abril de 2012

Structural basis for cytochrome c Y67H mutant to function as a peroxidase

artículo científico publicado en 2014

Lista de obras de

A Potent Germline-like Human Monoclonal Antibody Targets a pH-Sensitive Epitope on H7N9 Influenza Hemagglutinin.

A Route to Novel Functional Metalloproteins via Hybrids of Cytochrome P450 and Cytochrome c ⬇️

A Single Dose of Anti-HBsAg Antibody-Encoding mRNA-LNPs Suppressed HBsAg Expression: a Potential Cure of Chronic Hepatitis B Virus Infection

A Unique Human Immunoglobulin Heavy Chain Variable Domain-Only CD33 CAR for the Treatment of Acute Myeloid Leukemia

A broadly neutralizing germline-like human monoclonal antibody against dengue virus envelope domain III

A defucosylated bispecific multivalent molecule exhibits broad HIV-1-neutralizing activity and enhanced antibody-dependent cellular cytotoxicity against reactivated HIV-1 latently infected cells

A native-like bispecific antibody suppresses the inflammatory cytokine response by simultaneously neutralizing tumor necrosis factor-alpha and interleukin-17A.

A novel coronavirus (2019-nCoV) causing pneumonia-associated respiratory syndrome

A novel insight into the heme and NO/CO binding mechanism of the alpha subunit of human soluble guanylate cyclase ⬇️

A systems approach to HIV-1 vaccines.

An immunogen containing four tandem 10E8 epitope repeats with exposed key residues induces antibodies that neutralize HIV-1 and activates an ADCC reporter gene

Antibody-based candidate therapeutics against HIV-1: implications for virus eradication and vaccine design.

Bispecific Engineered Antibody Domains (Nanoantibodies) That Interact Noncompetitively with an HIV-1 Neutralizing Epitope and FcRn ⬇️

Conformational Toggling of Yeast Iso-1-Cytochrome c in the Oxidized and Reduced States ⬇️

Development of Small-Molecule Inhibitors Against Zika Virus Infection

Development of Small-Molecule MERS-CoV Inhibitors

Development of human neutralizing monoclonal antibodies for prevention and therapy of MERS-CoV infections

Development of small-molecule inhibitors against hantaviruses

Development of therapeutics for treatment of Ebola virus infection.

Discovery of T-Cell Infection and Apoptosis by Middle East Respiratory Syndrome Coronavirus

Discovery of novel candidate therapeutics and diagnostics based on engineered human antibody domains.

Editorial: Antibody Fc Engineering: Towards Better Therapeutics

Efficacy of antibody-based therapies against Middle East respiratory syndrome coronavirus (MERS-CoV) in common marmosets.

Engineered Fc based antibody domains and fragments as novel scaffolds

Engineered Soluble Monomeric IgG1 Fc with Significantly Decreased Non-Specific Binding.

Engineered antibody domains with significantly increased transcytosis and half-life in macaques mediated by FcRn

Engineered soluble monomeric IgG1 CH3 domain: generation, mechanisms of function, and implications for design of biological therapeutics.

Engineering a Novel Antibody-Peptide Bispecific Fusion Protein Against MERS-CoV

Escape from humoral immunity is associated with treatment failure in HIV-1-infected patients receiving long-term antiretroviral therapy.

Establishment of Novel Monoclonal Fabs Specific for Epstein-Barr Virus Encoded Latent Membrane Protein 1

Evaluation of antiviral - passive - active immunization ("sandwich") therapeutic strategy for functional cure of chronic hepatitis B in mice

Exceptionally potent and broadly cross-reactive, bispecific multivalent HIV-1 inhibitors based on single human CD4 and antibody domains.

Exceptionally potent neutralization of Middle East respiratory syndrome coronavirus by human monoclonal antibodies.

Fc Engineering: Tailored Synthetic Human IgG1-Fc Repertoire for High-Affinity Interaction with FcRn at pH 6.0

From therapeutic antibodies to chimeric antigen receptors (CARs): making better CARs based on antigen-binding domain.

Fucoidan Extracted from the New Zealand -Physicochemical Comparison against Five Other Fucoidans: Unique Low Molecular Weight Fraction Bioactivity in Breast Cancer Cell Lines

Functional mapping of B-cell linear epitopes of SARS-CoV-2 in COVID-19 convalescent population

Fusion mechanism of 2019-nCoV and fusion inhibitors targeting HR1 domain in spike protein

Germlining of the HIV-1 broadly neutralizing antibody domain m36

Human monoclonal antibodies as candidate therapeutics against emerging viruses

Immune Repertoire Diversity Correlated with Mortality in Avian Influenza A (H7N9) Virus Infected Patients.

Improving the CH1-CK heterodimerization and pharmacokinetics of 4Dm2m, a novel potent CD4-antibody fusion protein against HIV-1.

Interactions of IgG1 CH2 and CH3 Domains with FcRn

Investigation of Different Molecular Weight Fucoidan Fractions Derived from New Zealand in Combination with GroA Therapy in Prostate Cancer Cell Lines

Junctional and allele-specific residues are critical for MERS-CoV neutralization by an exceptionally potent germline-like antibody.

Linear epitopes of SARS-CoV-2 spike protein elicit neutralizing antibodies in COVID-19 patients

Manganese superoxide dismutase from human pathogen Clostridium difficile.

Middle East respiratory syndrome coronavirus (MERS-CoV) entry inhibitors targeting spike protein.

Monomeric IgG1 Fc molecules displaying unique Fc receptor interactions that are exploitable to treat inflammation-mediated diseases.

N-Butanol Subfraction of Brassica Rapa L. Promotes Reactive Oxygen Species Production and Induces Apoptosis of A549 Lung Adenocarcinoma Cells via Mitochondria-Dependent Pathway.

N-terminal truncation of an isolated human IgG1 CH2 domain significantly increases its stability and aggregation resistance

Neutralization of Zika virus by germline-like human monoclonal antibodies targeting cryptic epitopes on envelope domain III.

New Directions for Half-Life Extension of Protein Therapeutics: The Rise of Antibody Fc Domains and Fragments.

No evidence for a superior platform to develop therapeutic antibodies rapidly in response to MERS-CoV and other emerging viruses.

One-domain CD4 Fused to Human Anti-CD16 Antibody Domain Mediates Effective Killing of HIV-1-Infected Cells.

Passive Transfer of A Germline-like Neutralizing Human Monoclonal Antibody Protects Transgenic Mice Against Lethal Middle East Respiratory Syndrome Coronavirus Infection

Pharmacodynamics of long-acting folic acid-receptor targeted ritonavir-boosted atazanavir nanoformulations

Potent In Vivo NK Cell-mediated Elimination of HIV-1-Infected Cells Mobilized by a gp120-bispecific and Hexavalent Broadly Neutralizing Fusion Protein.

Potent binding of 2019 novel coronavirus spike protein by a SARS coronavirus-specific human monoclonal antibody

Potential Nutraceutical Use of Tribulus terrestris L. in Human Health

Precision immunomedicine

Preparation, Characterization, and Immuno-Enhancing Activity of Polysaccharides from Glycyrrhiza uralensis

Probing the role of the bridging C509 between the [Fe4S4] cubane and the [NipNid] centre in the A-cluster of acetyl-coenzyme A synthase ⬇️

Prophylaxis With a Middle East Respiratory Syndrome Coronavirus (MERS-CoV)-Specific Human Monoclonal Antibody Protects Rabbits From MERS-CoV Infection

Purification, characterization and bioactivities of polysaccharides from Pleurotus ferulae.

Rapid Elimination of Broadly Neutralizing Antibodies Correlates with Treatment Failure in the Acute Phase of Simian-Human Immunodeficiency Virus Infection

Recent Progress on Neutralizing Antibodies against Hepatitis B Virus and its Implications

Recent advances in developing small-molecule inhibitors against SARS-CoV-2

Receptor-binding domain-specific human neutralizing monoclonal antibodies against SARS-CoV and SARS-CoV-2

Soluble Monomeric IgG1 Fc ⬇️

Structural basis for cytochrome c Y67H mutant to function as a peroxidase