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Development of an allosteric inhibitor class blocking RNA elongation by the respiratory syncytial virus polymerase complex

scientific article published in Journal of Biological Chemistry

Evaluating Antibody Mediated Protection against Alpha, Beta, and Delta SARS-CoV-2 Variants of Concern in K18-hACE2 Transgenic Mice

artículo científico publicado en 2022

Fine mapping and characterization of the L-polymerase-binding domain of the respiratory syncytial virus phosphoprotein.

artículo científico publicado en 2015

Identification and characterization of the binding site of the respiratory syncytial virus phosphoprotein to RNA-free nucleoprotein.

artículo científico publicado en 2015

Oral prodrug of remdesivir parent GS-441524 is efficacious against SARS-CoV-2 in ferrets

artículo científico publicado en 2021

Orally efficacious broad-spectrum allosteric inhibitor of paramyxovirus polymerase

artículo científico publicado en 2020

Organization, Function, and Therapeutic Targeting of the Morbillivirus RNA-Dependent RNA Polymerase Complex

artículo científico publicado en 2016

Small Molecule Compounds That Inhibit Antioxidant Response Gene Expression in an Inducer-Dependent Manner

artículo científico publicado en 2020

Structure of the Respiratory Syncytial Virus Polymerase Complex

artículo científico publicado en 2019

The Unstructured Paramyxovirus Nucleocapsid Protein Tail Domain Modulates Viral Pathogenesis through Regulation of Transcriptase Activity.

artículo científico publicado en 2018

Viral evolution identifies a regulatory interface between paramyxovirus polymerase complex and nucleocapsid that controls replication dynamics

scientific article published on 04 March 2020

Visualizing the replication of respiratory syncytial virus in cells and in living mice.

artículo científico publicado en 2014

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