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'Omic approaches to preventing or managing metastatic breast cancer

artículo científico publicado en 2011

A Biobank of Breast Cancer Explants with Preserved Intra-tumor Heterogeneity to Screen Anticancer Compounds

artículo científico publicado en 2016

A Multi-center Study on the Reproducibility of Drug-Response Assays in Mammalian Cell Lines

scientific article published on 10 July 2019

A Technical Assessment of the Utility of Reverse Phase Protein Arrays for the Study of the Functional Proteome in Non-microdissected Human Breast Cancers

artículo científico publicado en 2010

A central role for RAF→MEK→ERK signaling in the genesis of pancreatic ductal adenocarcinoma.

artículo científico publicado en 2012

A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes

artículo científico publicado en 2006

A colorectal cancer classification system that associates cellular phenotype and responses to therapy

artículo científico publicado en 2013

A community effort to assess and improve drug sensitivity prediction algorithms.

artículo científico publicado en 2014

A conditional feedback loop regulates Ras activity through EphA2.

artículo científico publicado en 2005

A fluid membrane-based soluble ligand-display system for live-cell assays

artículo científico publicado en 2006

A framework for multiplex imaging optimization and reproducible analysis

artículo científico publicado en 2022

A fully integrated, three-dimensional fluorescence to electron microscopy correlative workflow

artículo científico publicado en 2017

A human breast cell model of preinvasive to invasive transition.

scientific article published on March 2008

A multi-center study on factors influencing the reproducibility of in vitro drug-response studies

A multi-encoder variational autoencoder controls multiple transformational features in single-cell image analysis

artículo científico publicado en 2022

A multi-omic analysis of MCF10A cells provides a resource for integrative assessment of ligand-mediated molecular and phenotypic responses

artículo científico publicado en 2022

A nanoplasmonic molecular ruler for measuring nuclease activity and DNA footprinting

artículo científico publicado en 2006

A new treasure in the breast cancer gene hunt

artículo científico publicado en 2011

A primer on regression methods for decoding cis-regulatory logic

artículo científico publicado en 2009

A robust prognostic signature for hormone-positive node-negative breast cancer

artículo científico publicado en 2013

A screen for genes that suppress loss of contact inhibition: identification of ING4 as a candidate tumor suppressor gene in human cancer

artículo científico publicado en 2004

A sequence-based survey of the complex structural organization of tumor genomes

artículo científico publicado en 2008

A systems analysis of the chemosensitivity of breast cancer cells to the polyamine analogue PG-11047.

artículo científico publicado en 2009

A workflow for visualizing human cancer biopsies using large-format electron microscopy

scientific article published on 12 March 2020

ARTIK-52 induces replication-dependent DNA damage and p53 activation exclusively in cells of prostate and breast cancer origin.

artículo científico publicado en 2015

ATM suppresses SATB1-induced malignant progression in breast epithelial cells

artículo científico publicado en 2012

Absence of telomerase and shortened telomeres have minimal effects on skin and pancreatic carcinogenesis elicited by viral oncogenes

artículo científico publicado en 2004

Abstract 731: Integrative genomic analysis to identify emergent enzalutamide resistance mechanisms in castration-resistant prostate cancer

article

Abstract LB010: SMMART Program: A multi-omics tumor board with a focus on breast cancer

artículo científico publicado en 2021

Abstract OT3-05-01: Adaptive Multi-Drug Treatment of Evolving Cancers (AMTEC): A Phase II, Open-Label, Study of Olaparib in Combination with either Durvalumab, Selumetinib or Capivasertib, or Ceralasertib Monotherapy in Patients with Metastatic TNBC

artículo científico publicado en 2023

Activity of distinct growth factor receptor network components in breast tumors uncovers two biologically relevant subtypes

artículo científico publicado en 2017

Activity of the kinesin spindle protein inhibitor ispinesib (SB-715992) in models of breast cancer

artículo científico publicado en 2010

Aging impacts transcriptomes but not genomes of hormone-dependent breast cancers

artículo científico publicado en 2007

Amplification and over-expression of MAP3K3 gene in human breast cancer promotes formation and survival of breast cancer cells.

artículo científico publicado en 2014

Amplification of 11q13 in ovarian carcinoma

artículo científico publicado en 2008

Amplification of MDS1/EVI1 and EVI1, located in the 3q26.2 amplicon, is associated with favorable patient prognosis in ovarian cancer

artículo científico publicado en 2007

Amplification of PVT1 contributes to the pathophysiology of ovarian and breast cancer.

artículo científico publicado en 2007

An integrated view of copy number and allelic alterations in the cancer genome using single nucleotide polymorphism arrays

artículo científico publicado en 2004

An integrative genomic and proteomic analysis of PIK3CA, PTEN, and AKT mutations in breast cancer

scientific article published on August 2008

An omic and multidimensional spatial atlas from serial biopsies of an evolving metastatic breast cancer

artículo científico publicado en 2022

Analysis of molecular inversion probe performance for allele copy number determination

artículo científico publicado en 2007

Application of flow karyotyping in prenatal detection of chromosome aberrations

artículo científico publicado en 1988

Array-based comparative genomic hybridization analysis identified cyclin D1 as a target oncogene at 11q13.3 in nasopharyngeal carcinoma

artículo científico publicado en 2005

Asparagine synthetase as a causal, predictive biomarker for L-asparaginase activity in ovarian cancer cells

artículo científico publicado en 2006

Atypical PKCiota contributes to poor prognosis through loss of apical-basal polarity and cyclin E overexpression in ovarian cancer.

artículo científico publicado en 2005

BREAST CANCER HISTOPATHOLOGY IMAGE ANALYSIS PIPELINE FOR TUMOR PURITY ESTIMATION.

artículo científico publicado en 2017

BRIT1 regulates early DNA damage response, chromosomal integrity, and cancer

artículo científico publicado en 2006

Basal subtype and MAPK/ERK kinase (MEK)-phosphoinositide 3-kinase feedback signaling determine susceptibility of breast cancer cells to MEK inhibition

artículo científico publicado en 2009

Bayesian Network Inference Modeling Identifies TRIB1 as a Novel Regulator of Cell-Cycle Progression and Survival in Cancer Cells

artículo científico publicado en 2017

Bayesian inference of signaling network topology in a cancer cell line

artículo científico publicado en 2012

Beta1 integrin inhibitory antibody induces apoptosis of breast cancer cells, inhibits growth, and distinguishes malignant from normal phenotype in three dimensional cultures and in vivo

artículo científico publicado en 2006

Biallelic inactivation of the thyroid hormone receptor beta1 gene in early stage breast cancer.

artículo científico publicado en 2002

Breast cancer genomes--form and function

artículo científico publicado en 2010

Breast tumor copy number aberration phenotypes and genomic instability

artículo científico publicado en 2006

CCR5 Governs DNA Damage Repair and Breast Cancer Stem Cell Expansion.

artículo científico publicado en 2018

COMPARISON OF SPARSE CODING AND KERNEL METHODS FOR HISTOPATHOLOGICAL CLASSIFICATION OF GLIOBASTOMA MULTIFORME.

artículo científico publicado en 2011

CUL4A induces epithelial-mesenchymal transition and promotes cancer metastasis by regulating ZEB1 expression.

artículo científico publicado en 2013

Cationic Polymer Modified Mesoporous Silica Nanoparticles for Targeted SiRNA Delivery to HER2+ Breast Cancer

artículo científico publicado en 2015

Causal network inference using biochemical kinetics

artículo científico publicado en 2014

Cell fusion potentiates tumor heterogeneity and reveals circulating hybrid cells that correlate with stage and survival

artículo científico publicado en 2018

Cellular effect of high doses of silica-coated quantum dot profiled with high throughput gene expression analysis and high content cellomics measurements

artículo científico publicado en 2006

Characterization and organization of DNA sequences adjacent to the human telomere associated repeat (TTAGGG)n.

artículo científico publicado en 1990

Characterization of a naturally occurring breast cancer subset enriched in epithelial-to-mesenchymal transition and stem cell characteristics

artículo científico publicado en 2009

Characterizing the immune microenvironment in high-risk ductal carcinoma in situ of the breast

artículo científico publicado en 2016

Chemotherapy response and recurrence-free survival in neoadjuvant breast cancer depends on biomarker profiles: results from the I-SPY 1 TRIAL (CALGB 150007/150012; ACRIN 6657).

artículo científico publicado en 2011

Chromosomal reassignment: YACs containing both YES1 and thymidylate synthase map to the short arm of chromosome 18

artículo científico publicado en 1993

Chromosome aberrations in solid tumors

artículo científico publicado en 2003

Chromosome heteromorphism quantified by high-resolution bivariate flow karyotyping

artículo científico publicado en 1989

Circulating tumor DNA dynamics using patient-customized assays are associated with outcome in neoadjuvantly treated breast cancer.

artículo científico publicado en 2019

Circulating-tumor DNA as an early detection and diagnostic tool

artículo científico publicado en 2017

Combating subclonal evolution of resistant cancer phenotypes

artículo científico publicado en 2017

Combinatorial Microenvironments Impose a Continuum of Cellular Responses to a Single Pathway-Targeted Anti-cancer Compound

artículo científico publicado en 2017

Comparative Genomic Hybridization

artículo científico publicado en 2001

Comparative analyses of gene copy number and mRNA expression in glioblastoma multiforme tumors and xenografts

scientific article published on 12 January 2009

Comparative genomic hybridization for molecular cytogenetic analysis of solid tumors

artículo científico publicado el 30 de octubre de 1992

Comprehensive genome sequence analysis of a breast cancer amplicon

artículo científico publicado en 2001

Computational BAC clone contig assembly for comprehensive genome analysis

artículo científico publicado en 2004

Construction and characterization of plasmid libraries enriched in sequences from single human chromosomes ⬇️

artículo científico publicado el 1 de diciembre de 1991

Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling.

artículo científico publicado en 2016

Copy number aberrations in mouse breast tumors reveal loci and genes important in tumorigenic receptor tyrosine kinase signaling

artículo científico publicado en 2005

Copy number gain of hsa-miR-569 at 3q26.2 leads to loss of TP53INP1 and aggressiveness of epithelial cancers.

artículo científico publicado en 2014

Correction: Decoupling of the PI3K Pathway via Mutation Necessitates Combinatorial Treatment in HER2+ Breast Cancer

artículo científico publicado en 2017

Cross-platform pathway-based analysis identifies markers of response to the PARP inhibitor olaparib

artículo científico publicado en 2012

Crosstalk between Aurora-A and p53: frequent deletion or downregulation of Aurora-A in tumors from p53 null mice

artículo científico publicado en 2007

Current development of targeted oligonucleotide-based cancer therapies: Perspective on HER2-positive breast cancer treatment

artículo científico publicado en 2016

Cyclic Multiplexed-Immunofluorescence (cmIF), a Highly Multiplexed Method for Single-Cell Analysis

artículo científico publicado en 2020

Cytogenetic analysis by in situ hybridization with fluorescently labeled nucleic acid probes

artículo científico publicado en 1986

DIRAS3 (ARHI) Blocks RAS/MAPK Signaling by Binding Directly to RAS and Disrupting RAS Clusters

scientific article published on 01 December 2019

Decoding the fine-scale structure of a breast cancer genome and transcriptome

artículo científico publicado en 2006

Decoupling of the PI3K Pathway via Mutation Necessitates Combinatorial Treatment in HER2+ Breast Cancer

artículo científico publicado en 2015

Deep learning based Nucleus Classification in pancreas histological images.

artículo científico publicado en 2017

Deletion of chromosome 11q predicts response to anthracycline-based chemotherapy in early breast cancer

artículo científico publicado en 2007

Detecting cancer by monitoring circulating tumor DNA

artículo científico publicado en 2014

Detection and mapping of amplified DNA sequences in breast cancer by comparative genomic hybridization

artículo científico publicado en 1994

Detection of a human chromosomal translocation t(8;9) in a baby with multiple malformations using two-color fluorescence in situ hybridization

artículo científico publicado en 1994

Detection of retinoblastoma gene copy number in metaphase chromosomes and interphase nuclei by fluorescence in situ hybridization

artículo científico publicado el 1 de enero de 1992

Development and implementation of the SUM breast cancer cell line functional genomics knowledge base

artículo científico publicado en 2020

Dicentric chromosome frequency analysis using slit-scan flow cytometry

artículo científico publicado en 1991

Dicer, Drosha, and outcomes in patients with ovarian cancer

artículo científico publicado en 2008

Differentiation-state plasticity is a targetable resistance mechanism in basal-like breast cancer

artículo científico publicado en 2018

Disentangling multidimensional spatio-temporal data into their common and aberrant responses

artículo científico publicado en 2015

Do breast cancer cell lines provide a relevant model of the patient tumor methylome?

artículo científico publicado en 2014

EGFR Intron 1 polymorphism in Asian Populations and its correlation with EGFR gene expression and amplification in breast tumor tissues

artículo científico publicado en 2006

ERBB2 amplification in breast cancer analyzed by fluorescence in situ hybridization ⬇️

artículo científico publicado el 15 de junio de 1992

ESR1 gene amplification in breast cancer: a common phenomenon?

artículo científico publicado en 2008

Efficient, interactive, and three-dimensional segmentation of cell nuclei in thick tissue sections.

artículo científico publicado en 1998

Elevated Levels of Proliferating and Recently Migrated Tumor-associated Macrophages Confer Increased Aggressiveness and Worse Outcomes in Breast Cancer ⬇️

artículo científico publicado el 24 de mayo de 2012

End-sequence profiling: sequence-based analysis of aberrant genomes

artículo científico publicado en 2003

Endocytic trafficking of laminin is controlled by dystroglycan and is disrupted in cancers

artículo científico publicado en 2014

Enhanced NF kappa B and AP-1 transcriptional activity associated with antiestrogen resistant breast cancer

artículo científico publicado en 2007

Enzymatic production of single-stranded DNA as a target for fluorescence in situ hybridization

scientific article published on 01 January 1988

Erratum to: Genome co-amplification upregulates a mitotic gene network activity that predicts outcome and response to mitotic protein inhibitors in breast cancer

artículo científico publicado en 2017

Erratum to: Modeling precision treatment of breast cancer

artículo científico publicado en 2015

Exact reconstruction of gene regulatory networks using compressive sensing

artículo científico publicado en 2014

Exome Sequencing of Cell-Free DNA from Metastatic Cancer Patients Identifies Clinically Actionable Mutations Distinct from Primary Disease

artículo científico publicado en 2015

Exome sequencing of desmoplastic melanoma identifies recurrent NFKBIE promoter mutations and diverse activating mutations in the MAPK pathway

artículo científico publicado en 2015

Exon-level microarray analyses identify alternative splicing programs in breast cancer

artículo científico publicado en 2010

Expanding the Diversity of Imaging-Based RNAi Screen Applications Using Cell Spot Microarrays

scientific article published on 11 April 2013

FOXA1 overexpression mediates endocrine resistance by altering the ER transcriptome and IL-8 expression in ER-positive breast cancer

artículo científico publicado en 2016

Flow karyotyping and sorting of human chromosomes

scientific article published on 01 January 1986

Fluorescent Imaging for In Situ Measurement of Drug Target Engagement and Cell Signaling Pathways

scientific article published on 19 February 2020

Frequent silencing of low density lipoprotein receptor-related protein 1B (LRP1B) expression by genetic and epigenetic mechanisms in esophageal squamous cell carcinoma

artículo científico publicado en 2004

Functional oncogene signatures guide rationally designed combination therapies to synergistically induce breast cancer cell death

scientific article published on 02 May 2016

Functional proteomics identifies miRNAs to target a p27/Myc/phospho-Rb signature in breast and ovarian cancer

artículo científico publicado en 2016

Functional proteomics identifies miRNAs to target a p27/Myc/phospho-Rb signature in breast and ovarian cancer.

artículo científico publicado en 2015

Gamma-Normal-Gamma mixture model for detecting differentially methylated loci in three breast cancer cell lines

artículo científico publicado en 2007

Genetic analysis using genomic representations

artículo científico publicado en 1998

Genetic differences in transcript responses to low-dose ionizing radiation identify tissue functions associated with breast cancer susceptibility

artículo científico publicado en 2012

Genome amplification of chromosome 20 in breast cancer

artículo científico publicado en 2003

Genome co-amplification upregulates a mitotic gene network activity that predicts outcome and response to mitotic protein inhibitors in breast cancer

artículo científico publicado en 2016

Genome wide DNA copy number analysis of serous type ovarian carcinomas identifies genetic markers predictive of clinical outcome

artículo científico publicado en 2012

Genome-wide Methylation Analysis Identifies Genes Specific to Breast Cancer Hormone Receptor Status and Risk of Recurrence ⬇️

artículo científico publicado el 8 de agosto de 2011

Genome-wide array CGH analysis of murine neuroblastoma reveals distinct genomic aberrations which parallel those in human tumors.

artículo científico publicado en 2003

Genome-wide perturbations by miRNAs map onto functional cellular pathways, identifying regulators of chromatin modifiers

artículo científico publicado en 2015

Genomic aberrations in normal tissue adjacent to HER2-amplified breast cancers: field cancerization or contaminating tumor cells?

artículo científico publicado en 2012

Genomic copy number analysis of non-small cell lung cancer using array comparative genomic hybridization: implications of the phosphatidylinositol 3-kinase pathway

artículo científico publicado en 2002

Glutamine sensitivity analysis identifies the xCT antiporter as a common triple-negative breast tumor therapeutic target

artículo científico publicado en 2013

HER2 Reactivation through Acquisition of the HER2 L755S Mutation as a Mechanism of Acquired Resistance to HER2-targeted Therapy in HER2+ Breast Cancer

artículo científico publicado en 2017

HER2 signaling pathway activation and response of breast cancer cells to HER2-targeting agents is dependent strongly on the 3D microenvironment

artículo científico publicado en 2009

High quality copy number and genotype data from FFPE samples using Molecular Inversion Probe (MIP) microarrays

artículo científico publicado en 2009

High-resolution mapping of genotype-phenotype relationships in cri du chat syndrome using array comparative genomic hybridization

artículo científico publicado en 2005

High-throughput method for analyzing methylation of CpGs in targeted genomic regions

artículo científico publicado en 2010

High-throughput, single-particle tracking reveals nested membrane domains that dictate KRasG12D diffusion and trafficking

scientific article published on 01 November 2019

How Machine Learning Will Transform Biomedicine

scientific article published on 01 April 2020

IL-10 and integrin signaling pathways are associated with head and neck cancer progression

artículo científico publicado en 2016

Identification of PADI2 as a potential breast cancer biomarker and therapeutic target

artículo científico publicado en 2012

Identification of a novel homozygous deletion region at 6q23.1 in medulloblastomas using high-resolution array comparative genomic hybridization analysis

artículo científico publicado en 2005

Identification of gene regulation patterns underlying both oestrogen- and tamoxifen-stimulated cell growth through global gene expression profiling in breast cancer cells.

artículo científico publicado en 2014

Immutable functional attributes of histologic grade revealed by context-independent gene expression in primary breast cancer cells

artículo científico publicado en 2009

Implementing a comprehensive translational oncology platform: from molecular testing to actionability

artículo científico publicado en 2018

In situ analyses of genome instability in breast cancer

artículo científico publicado en 2004

Increased risk of local recurrence is associated with allelic loss in normal lobules of breast cancer patients.

artículo científico publicado en 2002

Independent amplification and frequent co-amplification of three nonsyntenic regions on the long arm of chromosome 20 in human breast cancer

artículo científico publicado en 1996

Inferring causal molecular networks: empirical assessment through a community-based effort

artículo científico publicado en 2016

Inheritance of chromosome heteromorphisms analyzed by high-resolution bivariate flow karyotyping

artículo científico publicado en 1989

Integrated analysis of breast cancer cell lines reveals unique signaling pathways

artículo científico publicado en 2009

Integrated analysis of genome-wide DNA methylation and gene expression profiles in molecular subtypes of breast cancer

artículo científico publicado en 2013

Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1

artículo científico publicado en 2010

Integrating biological knowledge into variable selection: an empirical Bayes approach with an application in cancer biology

artículo científico publicado en 2012

Integrating data on DNA copy number with gene expression levels and drug sensitivities in the NCI-60 cell line panel ⬇️

artículo científico publicado en 2006

Integration of cytogenetic landmarks into the draft sequence of the human genome

artículo científico publicado en 2001

Integrative Analysis on Histopathological Image for Identifying Cellular Heterogeneity

artículo científico publicado en 2017

Integrative analysis of cyclin protein levels identifies cyclin b1 as a classifier and predictor of outcomes in breast cancer

artículo científico publicado en 2009

Interactive system for registering adjacent tissue sections

Invariant Delineation of Nuclear Architecture in Glioblastoma Multiforme for Clinical and Molecular Association ⬇️

artículo científico publicado el 4 de diciembre de 2012

Lack of acquired resistance in HER2-positive breast cancer cells after long-term HER2 siRNA nanoparticle treatment.

artículo científico publicado en 2018

Large-Scale Characterization of Drug Responses of Clinically Relevant Proteins in Cancer Cell Lines

artículo científico publicado en 2020

Large-Scale Drug Screens Support Precision Medicine

artículo científico publicado en 2015

Lectin chromatography/mass spectrometry discovery workflow identifies putative biomarkers of aggressive breast cancers

artículo científico publicado en 2012

Libraries for each human chromosome, constructed from sorter-enriched chromosomes by using linker-adaptor PCR.

artículo científico publicado en 1993

Linking changes in epithelial morphogenesis to cancer mutations using computational modeling

artículo científico publicado en 2010

Linking molecular diagnostics to molecular therapeutics: targeting the PI3K pathway in breast cancer

artículo científico publicado en 2003

Loss of cell-surface laminin anchoring promotes tumor growth and is associated with poor clinical outcomes

artículo científico publicado en 2012

Loss-of-function mutations in Notch receptors in cutaneous and lung squamous cell carcinoma

artículo científico publicado en 2011

Lrig1 is an estrogen-regulated growth suppressor and correlates with longer relapse-free survival in ERα-positive breast cancer

artículo científico publicado en 2011

MHC class I loaded ligands from breast cancer cell lines: A potential HLA-I-typed antigen collection

artículo científico publicado en 2018

MORPHOMETRIC SUBTYPING FOR A PANEL OF BREAST CANCER CELL LINES.

artículo científico publicado en 2009

Magellan: a web based system for the integrated analysis of heterogeneous biological data and annotations; application to DNA copy number and expression data in ovarian cancer

artículo científico publicado en 2006

Mapping and characterization of the amplicon near APOA2 in 1q23 in human sarcomas by FISH and array CGH

artículo científico publicado en 2005

Metrics other than potency reveal systematic variation in responses to cancer drugs.

artículo científico publicado en 2013

Microenvironment-Mediated Mechanisms of Resistance to HER2 Inhibitors Differ between HER2+ Breast Cancer Subtypes.

artículo científico publicado en 2018

Modeling Tumor Phenotypes In Vitro with Three-Dimensional Bioprinting

artículo científico publicado en 2019

Modeling precision treatment of breast cancer

artículo científico publicado en 2013

Molecular Cytogenetics Guides Massively Parallel Sequencing of a Radiation-Induced Chromosome Translocation in Human Cells.

artículo científico publicado en 2018

Molecular characterization of the cytotoxic mechanism of multiwall carbon nanotubes and nano-onions on human skin fibroblast

artículo científico publicado en 2005

Molecular cytogenetic analysis of consistent abnormalities at 8q12-q22 in breast cancer.

artículo científico publicado en 1998

Molecular cytogenetics in human cancer diagnosis

artículo científico publicado el 15 de marzo de 1992

Molecular cytogenetics: diagnosis and prognostic assessment

artículo científico publicado el 1 de diciembre de 1992

Molecular predictors of 3D morphogenesis by breast cancer cell lines in 3D culture

artículo científico publicado en 2010

Morphometic analysis of TCGA glioblastoma multiforme ⬇️

artículo científico publicado el 20 de diciembre de 2011

Multiomics analysis of serial PARP inhibitor treated metastatic TNBC inform on rational combination therapies

artículo científico publicado en 2021

Multiple roles of the candidate oncogene ZNF217 in ovarian epithelial neoplastic progression.

artículo científico publicado en 2007

Multiplexed immunohistochemistry image analysis using sparse coding

artículo científico publicado en 2017

NOEY2 (ARHI), an imprinted putative tumor suppressor gene in ovarian and breast carcinomas

artículo científico publicado en 1999

Nanoparticle-mediated systemic delivery of siRNA for treatment of cancers and viral infections

artículo científico publicado en 2014

Oligonucleotide conjugated antibodies permit highly multiplexed immunofluorescence for future use in clinical histopathology

artículo científico publicado en 2020

Oncogene expression and genetic background influence the frequency of DNA copy number abnormalities in mouse pancreatic islet cell carcinomas

artículo científico publicado en 2004

Optimization-based Inference for Temporally Evolving Networks with Applications in Biology ⬇️

artículo científico publicado el 1 de diciembre de 2012

Organic cation transporters are determinants of oxaliplatin cytotoxicity.

scientific article published on September 2006

Ovarian cancer: linking genomics to new target discovery and molecular markers--the way ahead

artículo científico publicado en 2008

Ovarian carcinomas with genetic and epigenetic BRCA1 loss have distinct molecular abnormalities

artículo científico publicado en 2008

Overcoming endocrine resistance due to reduced PTEN levels in estrogen receptor-positive breast cancer by co-targeting mammalian target of rapamycin, protein kinase B, or mitogen-activated protein kinase kinase.

artículo científico publicado en 2014

Overexpression of SnoN/SkiL, amplified at the 3q26.2 locus, in ovarian cancers: a role in ovarian pathogenesis

artículo científico publicado en 2008

PIK3CA is implicated as an oncogene in ovarian cancer.

artículo científico publicado en 1999

PLK1 and EGFR targeted nanoparticle as a radiation sensitizer for non-small cell lung cancer

artículo científico publicado en 2019

Pancreatic insulinomas in multiple endocrine neoplasia, type I knockout mice can develop in the absence of chromosome instability or microsatellite instability.

artículo científico publicado en 2004

Pathologic complete response predicts recurrence-free survival more effectively by cancer subset: results from the I-SPY 1 TRIAL--CALGB 150007/150012, ACRIN 6657.

artículo científico publicado en 2012

Pathway-Enriched Gene Signature Associated with 53BP1 Response to PARP Inhibition in Triple-Negative Breast Cancer.

artículo científico publicado en 2017

Phylogenetic analyses of melanoma reveal complex patterns of metastatic dissemination.

artículo científico publicado en 2015

Picomolar sensitivity MRI and photoacoustic imaging of cobalt nanoparticles

artículo científico publicado en 2009

Positional cloning of ZNF217 and NABC1: genes amplified at 20q13.2 and overexpressed in breast carcinoma

artículo científico publicado en 1998

Predicting primary site of secondary liver cancer with a neural estimator of metastatic origin

artículo científico publicado en 2020

Prediction of epigenetically regulated genes in breast cancer cell lines

artículo científico publicado en 2010

Prognostic value of PAI1 in invasive breast cancer: evidence that tumor-specific factors are more important than genetic variation in regulating PAI1 expression

artículo científico publicado en 2006

Prognostically relevant gene signatures of high-grade serous ovarian carcinoma

artículo científico publicado en 2012

Protein elongation factor EEF1A2 is a putative oncogene in ovarian cancer

artículo científico publicado en 2002

Proteomic and transcriptomic profiling reveals a link between the PI3K pathway and lower estrogen-receptor (ER) levels and activity in ER+ breast cancer

artículo científico publicado en 2010

Publisher Correction: Combating subclonal evolution of resistant cancer phenotypes

artículo científico publicado en 2018

Qdot nanobarcodes for multiplexed gene expression analysis

artículo científico publicado en 2006

Quantification of sensitivity and resistance of breast cancer cell lines to anti-cancer drugs using GR metrics

artículo científico publicado en 2017

Quantitating morphological changes in biological samples during scanning electron microscopy sample preparation with correlative super-resolution microscopy

artículo científico publicado en 2017

Quantitative DNA fiber mapping

artículo científico publicado en 1995

Quantitative Multiplex Immunohistochemistry Reveals Myeloid-Inflamed Tumor-Immune Complexity Associated with Poor Prognosis.

artículo científico publicado en 2017

Quantitative analysis of chromosomal CGH in human breast tumors associates copy number abnormalities with p53 status and patient survival

artículo científico publicado en 2001

Quantitative analysis of histological tissue image based on cytological profiles and spatial statistics

artículo científico publicado en 2016

Quantitative mRNA expression analysis from formalin-fixed, paraffin-embedded tissues using 5' nuclease quantitative reverse transcription-polymerase chain reaction

artículo científico publicado en 2000

Quantitative mapping of amplicon structure by array CGH identifies CYP24 as a candidate oncogene

artículo científico publicado en 2000

Quantitative, in situ analysis of mRNAs and proteins with subcellular resolution.

artículo científico publicado en 2017

Quantum dots-based reverse phase protein microarray

artículo científico publicado en 2005

RESTORE: Robust intEnSiTy nORmalization mEthod for multiplexed imaging

artículo científico publicado en 2020

Rab25 increases cellular ATP and glycogen stores protecting cancer cells from bioenergetic stress

artículo científico publicado en 2012

Radiosensitivity profiles from a panel of ovarian cancer cell lines exhibiting genetic alterations in p53 and disparate DNA-dependent protein kinase activities

artículo científico publicado en 2010

Ras-GTP dimers activate the Mitogen-Activated Protein Kinase (MAPK) pathway

artículo científico publicado en 2015

Rbfox proteins regulate alternative mRNA splicing through evolutionarily conserved RNA bridges.

artículo científico publicado en 2013

Reconciliation of classification systems defining molecular subtypes of colorectal cancer: interrelationships and clinical implications.

artículo científico publicado en 2014

Reconstruction of Gene Regulatory Networks based on Repairing Sparse Low-rank Matrices

artículo científico publicado en 2015

Reconstruction of functionally normal and malignant human breast tissues in mice

scholarly article

Reply to Colorectal cancer classification based on gene expression is not associated with FOLFIRI response

scientific article published on 01 November 2014

Restriction of receptor movement alters cellular response: physical force sensing by EphA2.

artículo científico publicado en 2010

Retrieving common dynamics of gene regulatory networks under various perturbations

artículo científico publicado en 2015

Risk estimation of distant metastasis in node-negative, estrogen receptor-positive breast cancer patients using an RT-PCR based prognostic expression signature

artículo científico publicado en 2008

Robust Cell Detection and Segmentation for Image Cytometry Reveal Th17 Cell Heterogeneity

scientific article published on 04 February 2019

SHIFT: speedy histological-to-immunofluorescent translation of a tumor signature enabled by deep learning

artículo científico publicado en 2020

SHIFT: speedy histopathological-to-immunofluorescent translation of whole slide images using conditional generative adversarial networks

Signal removal methods for highly multiplexed immunofluorescent staining using antibody conjugated oligonucleotides

scientific article published on 01 February 2019

Simultaneous Multicolor Single-Molecule Tracking with Single-Laser Excitation via Spectral Imaging

artículo científico publicado en 2018

Single-molecule superresolution imaging allows quantitative analysis of RAF multimer formation and signaling

scientific article published on 24 October 2013

Sparse combinatorial inference with an application in cancer biology

artículo científico publicado en 2008

Sparse multitask regression for identifying common mechanism of response to therapeutic targets

artículo científico publicado en 2010

Specific keynote: genome copy number abnormalities in ovarian cancer

artículo científico publicado en 2003

Specific keynote: molecular therapeutics in ovarian cancer

artículo científico publicado en 2003

Stabilization of chromosomes by DNA intercalators for flow karyotyping and identification by banding of isolated chromosomes

artículo científico publicado en 1987

Stromal-epithelial interactions in the progression of ovarian cancer: influence and source of tumor stromal cells

artículo científico publicado en 2001

Structural chromosome analysis by whole chromosome painting for assessment of radiation-induced genetic damage

artículo científico publicado el 1 de marzo de 1992

Subtype and pathway specific responses to anticancer compounds in breast cancer

artículo científico publicado en 2011

Subtypes of pancreatic ductal adenocarcinoma and their differing responses to therapy

artículo científico publicado en 2011

Synthesis of Y chromosome-specific labeled DNA probes by in vitro DNA amplification

artículo científico publicado en 1990

Systems biology in cancer research: genomics to cellomics

artículo científico publicado en 2007

TBX3 and its isoform TBX3+2a are functionally distinctive in inhibition of senescence and are overexpressed in a subset of breast cancer cell lines

artículo científico publicado en 2004

Targeted Treatment of Metastatic Breast Cancer by PLK1 siRNA Delivered by an Antioxidant Nanoparticle Platform

artículo científico publicado en 2017

Targeting mitochondria in cancer therapy could provide a basis for the selective anti-cancer activity

artículo científico publicado en 2019

Targeting the Mevalonate Pathway to Overcome Acquired Anti-HER2 Treatment Resistance in Breast Cancer

scientific article published on 16 August 2019

Targeting uPAR with Antagonistic Recombinant Human Antibodies in Aggressive Breast Cancer ⬇️

artículo científico publicado el 11 de febrero de 2013

Temporal dissection of tumorigenesis in primary cancers

artículo científico publicado en 2011

The ErbB2ΔEx16 splice variant is a major oncogenic driver in breast cancer that promotes a pro-metastatic tumor microenvironment

artículo científico publicado en 2016

The Human Tumor Atlas Network: Charting Tumor Transitions across Space and Time at Single-Cell Resolution

scientific article published on 01 April 2020

The Library of Integrated Network-Based Cellular Signatures NIH Program: System-Level Cataloging of Human Cells Response to Perturbations

artículo científico publicado en 2017

The RAB25 small GTPase determines aggressiveness of ovarian and breast cancers

artículo científico publicado en 2004

The consensus molecular subtypes of colorectal cancer

artículo científico publicado en 2015

The eukaryotic translation elongation factor eEF1A2 induces neoplastic properties and mediates tumorigenic effects of ZNF217 in precursor cells of human ovarian carcinomas

artículo científico publicado en 2008

The expression level of HJURP has an independent prognostic impact and predicts the sensitivity to radiotherapy in breast cancer

artículo científico publicado en 2010

The genetics and genomics of cancer

artículo científico publicado en 2003

The melanocyte differentiation program predisposes to metastasis after neoplastic transformation

artículo científico publicado en 2005

The morphologies of breast cancer cell lines in three-dimensional assays correlate with their profiles of gene expression.

artículo científico publicado en 2007

The role of p53 in suppression of KSHV cyclin-induced lymphomagenesis

artículo científico publicado en 2004

The stromal proteinase MMP3/stromelysin-1 promotes mammary carcinogenesis

artículo científico publicado en 1999

The transcription factor ZNF217 is a prognostic biomarker and therapeutic target during breast cancer progression

artículo científico publicado en 2012

Therapeutic Clues from an Integrated Omic Assessment of East Asian Triple Negative Breast Cancers

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Therapeutic siRNA for drug-resistant HER2-positive breast cancer.

artículo científico publicado en 2016

Timing chromosomal abnormalities using mutation data.

artículo científico publicado en 2011

Topographic enhancement mapping of the cancer-associated breast stroma using breast MRI ⬇️

artículo científico publicado el 18 de marzo de 2011

Toward reproducible, scalable, and robust data analysis across multiplex tissue imaging platforms

artículo científico publicado en 2021

Transcription restores DNA repair to heterochromatin, determining regional mutation rates in cancer genomes.

artículo científico publicado en 2014

Transcriptional Programming of Normal and Inflamed Human Epidermis at Single-Cell Resolution

artículo científico publicado en 2018

Transcriptional signatures in histologic structures within glioblastoma tumors may predict personalized drug sensitivity and survival

scientific article published on 01 January 2020

Translating insights from the cancer genome into clinical practice

artículo científico publicado en 2008

Translational Research Working Group developmental pathway for biospecimen-based assessment modalities

artículo científico publicado en 2008

Translational crossroads for biomarkers

artículo científico publicado en 2005

Tumor-Derived Cell Lines as Molecular Models of Cancer Pharmacogenomics

artículo científico publicado en 2016

Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation ⬇️

artículo científico publicado el 1 de octubre de 1998

Two-color hybridization with high complexity chromosome-specific probes and a degenerate alpha satellite probe DNA allows unambiguous discrimination between symmetrical and asymmetrical translocations

artículo científico publicado en 1991

Upregulation of ER Signaling as an Adaptive Mechanism of Cell Survival in HER2-Positive Breast Tumors Treated with Anti-HER2 Therapy.

artículo científico publicado en 2015

Using Microarrays to Interrogate Microenvironmental Impact on Cellular Phenotypes in Cancer

scientific article published on 21 May 2019

Using monoclonal antibodies in bromodeoxyuridine-DNA analysis

artículo científico publicado el 1 de enero de 1990

VISTA: VIsual Semantic Tissue Analysis for pancreatic disease quantification in murine cohorts

artículo científico publicado en 2020

Variational Autoencoding Tissue Response to Microenvironment Perturbation

scientific article published on 01 February 2019

What are we learning from the cancer genome? ⬇️

artículo científico publicado el 11 de septiembre de 2012

Xenografts faithfully recapitulate breast cancer-specific gene expression patterns of parent primary breast tumors

artículo científico publicado en 2012

Yin yang 1 modulates taxane response in epithelial ovarian cancer

artículo científico publicado en 2009

c-Src modulates estrogen-induced stress and apoptosis in estrogen-deprived breast cancer cells

artículo científico publicado en 2013

p27Kip1 mediates addiction of ovarian cancer cells to MYCC (c-MYC) and their dependence on MYC paralogs

artículo científico publicado en 2010

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