Lista de obras -

52 Genetic Loci Influencing Myocardial Mass

artículo científico publicado en 2016

A High Density Association Study of the Extended Major Histocompatibility Locus in Ulcerative Colitis

article published in 2007

A genome-wide association study of marginal zone lymphoma shows association to the HLA region

artículo científico publicado en 2015

A large-scale genetic analysis reveals a strong contribution of the HLA class II region to giant cell arteritis susceptibility ⬇️

artículo científico publicado en 2015

A novel MMP12 locus is associated with large artery atherosclerotic stroke using a genome-wide age-at-onset informed approach

artículo científico publicado en 2014

A reference panel of 64,976 haplotypes for genotype imputation

artículo científico publicado en 2016

A second generation human haplotype map of over 3.1 million SNPs

artículo científico publicado en 2007

Abstract 5072: Meta-analysis of genome-wide association studies identifies novel susceptibility loci for follicular lymphoma

Angiogenin variants in Parkinson disease and amyotrophic lateral sclerosis

artículo científico

Annotation of loci from genome-wide association studies using tissue-specific quantitative interaction proteomics

artículo científico publicado en 2014

Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data

artículo científico publicado en 2014

Association of common variation in the HNF1alpha gene region with risk of type 2 diabetes

scientific article published on 01 August 2005

Association testing of variants in the hepatocyte nuclear factor 4alpha gene with risk of type 2 diabetes in 7,883 people

artículo científico publicado en 2005

Atrial fibrillation genetic risk differentiates cardioembolic stroke from other stroke subtypes

C9orf72 and UNC13A are shared risk loci for amyotrophic lateral sclerosis and frontotemporal dementia: a genome-wide meta-analysis

artículo científico publicado en 2014

Coding variants at hexa-allelic amino acid 13 of HLA-DRB1 explain independent SNP associations with follicular lymphoma risk

artículo científico publicado en 2013

Common missense variant in the glucokinase regulatory protein gene is associated with increased plasma triglyceride and C-reactive protein but lower fasting glucose concentrations

artículo científico publicado en 2008

Common mitochondrial sequence variants in ischemic stroke

artículo científico publicado en 2010

Common variants at 30 loci contribute to polygenic dyslipidemia

artículo científico publicado en 2009

Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction

artículo científico publicado en 2010

Common variants in KCNN3 are associated with lone atrial fibrillation

artículo científico publicado en 2010

Common variants in the HLA-DQ region confer susceptibility to idiopathic achalasia.

artículo científico publicado en 2014

Comprehensive association testing of common mitochondrial DNA variation in metabolic disease

artículo científico publicado en 2006

Concept, design and implementation of a cardiovascular gene-centric 50 k SNP array for large-scale genomic association studies

artículo científico publicado en 2008

Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

artículo científico publicado en 2016

Cystatin C and Cardiovascular Disease: A Mendelian Randomization Study

artículo científico publicado en 2016

Defining the role of common variation in the genomic and biological architecture of adult human height

artículo científico publicado en 2014

ERRATUM: Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height

article by Matthew B. Lanktree et al published June 2012 in American Journal of Human Genetics

Efficiency and power in genetic association studies

artículo científico publicado en 2005

Erratum: Genetic loci associated with heart rate variability and their effects on cardiac disease risk

artículo científico publicado en 2017

Evaluating and improving power in whole-genome association studies using fixed marker sets.

artículo científico publicado en 2006

Exome sequencing and the genetic basis of complex traits

artículo científico publicado en 2012

Exome-chip association analysis of intracranial aneurysms

scientific article published on 15 November 2019

Extremely low-coverage sequencing and imputation increases power for genome-wide association studies

artículo científico publicado en 2012

Fine mapping in the MHC region accounts for 18% additional genetic risk for celiac disease

artículo científico publicado en 2015

Fine mapping seronegative and seropositive rheumatoid arthritis to shared and distinct HLA alleles by adjusting for the effects of heterogeneity.

artículo científico publicado en 2014

Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis

artículo científico publicado en 2012

Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci

artículo científico publicado en 2014

Genetic Susceptibility Loci for Cardiovascular Disease and Their Impact on Atherosclerotic Plaques

Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting

Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization

artículo científico publicado en 2014

Genetic loci associated with heart rate variability and their effects on cardiac disease risk

artículo científico publicado en 2017

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

artículo científico publicado en 2011

Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE collaboration): a meta-analysis of genome-wide association studies

artículo científico publicado en 2012

Genetic risk scores and number of autoantibodies in patients with rheumatoid arthritis

artículo científico publicado en 2013

Genetic studies of body mass index yield new insights for obesity biology

artículo científico publicado en 2015

Genetic variation at 16q24.2 is associated with small vessel stroke

artículo científico publicado en 2016

Genetically predicted longer telomere length is associated with increased risk of B-cell lymphoma subtypes

artículo científico publicado en 2016

Genome of The Netherlands population-specific imputations identify an ABCA6 variant associated with cholesterol levels

artículo científico publicado en 2015

Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis

artículo científico publicado en 2016

Genome-wide association analysis identifies multiple loci related to resting heart rate

artículo científico publicado en 2010

Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits

artículo científico publicado en 2019

Genome-wide association meta-analysis of PR interval identifies 47 novel loci associated with atrial and atrioventricular electrical activity

Genome-wide association study identifies five susceptibility loci for follicular lymphoma outside the HLA region

artículo científico publicado en 2014

Genome-wide association study identifies multiple susceptibility loci for diffuse large B cell lymphoma

artículo científico publicado en 2014

Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci

artículo científico publicado en 2010

Genome-wide detection and characterization of positive selection in human populations

artículo científico publicado en 2007

Genome-wide meta-analysis identifies multiple novel associations and ethnic heterogeneity of psoriasis susceptibility

artículo científico publicado en 2015

Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci

artículo científico publicado en 2011

Genome-wide meta-analysis in alopecia areata resolves HLA associations and reveals two new susceptibility loci

artículo científico publicado en 2015

Haplotype structure and genotype-phenotype correlations of the sulfonylurea receptor and the islet ATP-sensitive potassium channel gene region

artículo científico publicado en 2004

Haplotype structures and large-scale association testing of the 5' AMP-activated protein kinase genes PRKAA2, PRKAB1, and PRKAB2 [corrected] with type 2 diabetes

artículo científico publicado en 2006

High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis

artículo científico publicado en 2012

High-density haplotype structure and association testing of the insulin-degrading enzyme (IDE) gene with type 2 diabetes in 4,206 people

artículo científico publicado en 2006

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders

artículo científico publicado en 2013

Impact of carotid atherosclerosis loci on cardiovascular events.

artículo científico publicado en 2015

Improved imputation quality of low-frequency and rare variants in European samples using the 'Genome of The Netherlands'.

artículo científico publicado en 2014

Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies

artículo científico publicado en 2012

Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci

artículo científico publicado en 2012

Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci

artículo científico publicado en 2012

Loci influencing blood pressure identified using a cardiovascular gene-centric array

artículo científico publicado en 2013

Loci influencing blood pressure identified using a cardiovascular gene-centric array.

artículo científico publicado en 2013

Low frequency and rare coding variation contributes to multiple sclerosis risk

Mapping of multiple susceptibility variants within the MHC region for 7 immune-mediated diseases

artículo científico publicado en 2009

Meta-Analysis of Genome-Wide Association Studies for Abdominal Aortic Aneurysm Identifies Four New Disease-Specific Risk Loci ⬇️

artículo científico publicado en 2016

Meta-analysis in more than 17,900 cases of ischemic stroke reveals a novel association at 12q24.12.

artículo científico publicado en 2014

Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height

artículo científico publicado en 2010

Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci

artículo científico publicado en 2009

Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

artículo científico publicado en 2008

Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci

scientific journal article

Modeling the cumulative genetic risk for multiple sclerosis from genome-wide association data

artículo científico publicado en 2011

Myosin IXB variant increases the risk of celiac disease and points toward a primary intestinal barrier defect

artículo científico publicado en 2005

Negative selection in humans and fruit flies involves synergistic epistasis.

artículo científico publicado en 2017

No evidence for shared genetic basis of common variants in multiple sclerosis and amyotrophic lateral sclerosis

artículo científico publicado en 2013

PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity

artículo científico publicado en 2018

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

article

Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study

artículo científico publicado en 2012

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2017

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

article

Publisher Correction: Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

artículo científico publicado en 2019

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2019

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.

artículo científico publicado en 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.

artículo científico publicado en 2018

Quantitative trait loci for CD4:CD8 lymphocyte ratio are associated with risk of type 1 diabetes and HIV-1 immune control

artículo científico publicado en 2009

Rare and low-frequency coding variants alter human adult height

artículo científico publicado en 2017

STAT4 and the risk of rheumatoid arthritis and systemic lupus erythematosus

artículo científico publicado en 2007

Seventy-five genetic loci influencing the human red blood cell

artículo científico publicado en 2012

Shared Genetic Risk Factors of Intracranial, Abdominal, and Thoracic Aneurysms

artículo científico publicado en 2016

Stroke Genetics Network (SiGN) study: design and rationale for a genome-wide association study of ischemic stroke subtypes

artículo científico publicado en 2013

The Genome of the Netherlands: design, and project goals

artículo científico publicado en 2014

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

artículo científico publicado en 2015

The Multiple Sclerosis Genomic Map: Role of peripheral immune cells and resident microglia in susceptibility

scholarly article published 13 July 2017

The role of the CD58 locus in multiple sclerosis

artículo científico publicado en 2009

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

artículo científico publicado en 2016

Transferability of tag SNPs in genetic association studies in multiple populations

scientific article published on 22 October 2006

Two independent alleles at 6q23 associated with risk of rheumatoid arthritis

artículo científico publicado en 2007

Variants in ALOX5, ALOX5AP and LTA4H are not associated with atherosclerotic plaque phenotypes: the Athero-Express Genomics Study

artículo científico publicado en 2015

Widespread non-additive and interaction effects within HLA loci modulate the risk of autoimmune diseases

artículo científico publicado en 2015

Lista de obras de

52 Genetic Loci Influencing Myocardial Mass

A High Density Association Study of the Extended Major Histocompatibility Locus in Ulcerative Colitis

A genome-wide association study of marginal zone lymphoma shows association to the HLA region

A large-scale genetic analysis reveals a strong contribution of the HLA class II region to giant cell arteritis susceptibility ⬇️

A novel MMP12 locus is associated with large artery atherosclerotic stroke using a genome-wide age-at-onset informed approach

A reference panel of 64,976 haplotypes for genotype imputation

A second generation human haplotype map of over 3.1 million SNPs

Abstract 5072: Meta-analysis of genome-wide association studies identifies novel susceptibility loci for follicular lymphoma

Angiogenin variants in Parkinson disease and amyotrophic lateral sclerosis

Annotation of loci from genome-wide association studies using tissue-specific quantitative interaction proteomics

Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data

Association of common variation in the HNF1alpha gene region with risk of type 2 diabetes

Association testing of variants in the hepatocyte nuclear factor 4alpha gene with risk of type 2 diabetes in 7,883 people

Atrial fibrillation genetic risk differentiates cardioembolic stroke from other stroke subtypes

C9orf72 and UNC13A are shared risk loci for amyotrophic lateral sclerosis and frontotemporal dementia: a genome-wide meta-analysis

Coding variants at hexa-allelic amino acid 13 of HLA-DRB1 explain independent SNP associations with follicular lymphoma risk

Common missense variant in the glucokinase regulatory protein gene is associated with increased plasma triglyceride and C-reactive protein but lower fasting glucose concentrations

Common mitochondrial sequence variants in ischemic stroke

Common variants at 30 loci contribute to polygenic dyslipidemia

Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction

Common variants in KCNN3 are associated with lone atrial fibrillation

Common variants in the HLA-DQ region confer susceptibility to idiopathic achalasia.

Comprehensive association testing of common mitochondrial DNA variation in metabolic disease

Concept, design and implementation of a cardiovascular gene-centric 50 k SNP array for large-scale genomic association studies

Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

Cystatin C and Cardiovascular Disease: A Mendelian Randomization Study

Defining the role of common variation in the genomic and biological architecture of adult human height

ERRATUM: Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height

Efficiency and power in genetic association studies

Erratum: Genetic loci associated with heart rate variability and their effects on cardiac disease risk

Evaluating and improving power in whole-genome association studies using fixed marker sets.

Exome sequencing and the genetic basis of complex traits

Exome-chip association analysis of intracranial aneurysms

Extremely low-coverage sequencing and imputation increases power for genome-wide association studies

Fine mapping in the MHC region accounts for 18% additional genetic risk for celiac disease

Fine mapping seronegative and seropositive rheumatoid arthritis to shared and distinct HLA alleles by adjusting for the effects of heterogeneity.

Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis

Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci

Genetic Susceptibility Loci for Cardiovascular Disease and Their Impact on Atherosclerotic Plaques

Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting

Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization

Genetic loci associated with heart rate variability and their effects on cardiac disease risk

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE collaboration): a meta-analysis of genome-wide association studies

Genetic risk scores and number of autoantibodies in patients with rheumatoid arthritis

Genetic studies of body mass index yield new insights for obesity biology

Genetic variation at 16q24.2 is associated with small vessel stroke

Genetically predicted longer telomere length is associated with increased risk of B-cell lymphoma subtypes

Genome of The Netherlands population-specific imputations identify an ABCA6 variant associated with cholesterol levels

Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis

Genome-wide association analysis identifies multiple loci related to resting heart rate

Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits

Genome-wide association meta-analysis of PR interval identifies 47 novel loci associated with atrial and atrioventricular electrical activity

Genome-wide association study identifies five susceptibility loci for follicular lymphoma outside the HLA region

Genome-wide association study identifies multiple susceptibility loci for diffuse large B cell lymphoma

Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci

Genome-wide detection and characterization of positive selection in human populations

Genome-wide meta-analysis identifies multiple novel associations and ethnic heterogeneity of psoriasis susceptibility

Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci

Genome-wide meta-analysis in alopecia areata resolves HLA associations and reveals two new susceptibility loci

Haplotype structure and genotype-phenotype correlations of the sulfonylurea receptor and the islet ATP-sensitive potassium channel gene region

Haplotype structures and large-scale association testing of the 5' AMP-activated protein kinase genes PRKAA2, PRKAB1, and PRKAB2 [corrected] with type 2 diabetes

High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis

High-density haplotype structure and association testing of the insulin-degrading enzyme (IDE) gene with type 2 diabetes in 4,206 people

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders

Impact of carotid atherosclerosis loci on cardiovascular events.

Improved imputation quality of low-frequency and rare variants in European samples using the 'Genome of The Netherlands'.

Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies

Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci

Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci

Loci influencing blood pressure identified using a cardiovascular gene-centric array

Loci influencing blood pressure identified using a cardiovascular gene-centric array.

Low frequency and rare coding variation contributes to multiple sclerosis risk

Mapping of multiple susceptibility variants within the MHC region for 7 immune-mediated diseases

Meta-Analysis of Genome-Wide Association Studies for Abdominal Aortic Aneurysm Identifies Four New Disease-Specific Risk Loci ⬇️

Meta-analysis in more than 17,900 cases of ischemic stroke reveals a novel association at 12q24.12.

Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height

Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci

Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes