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A novel lipoate attachment enzyme is shared by Plasmodium and Chlamydia species.

artículo científico publicado en 2017

Challenges and Hallmarks of Establishing Alkylacetylphosphonates as Probes of Bacterial 1-Deoxy-d-xylulose 5-Phosphate Synthase.

artículo científico publicado en 2017

Enamide Prodrugs of Acetyl Phosphonate Deoxy-d-xylulose-5-phosphate Synthase Inhibitors as Potent Antibacterial Agents

artículo científico publicado en 2019

Growth medium-dependent antimicrobial activity of early stage MEP pathway inhibitors.

artículo científico publicado en 2018

Hydroxybenzaldoximes Are D-GAP-Competitive Inhibitors of E. coli 1-Deoxy-D-Xylulose-5-Phosphate Synthase

artículo científico publicado en 2015

Identification of an Atg8-Atg3 protein-protein interaction inhibitor from the medicines for Malaria Venture Malaria Box active in blood and liver stage Plasmodium falciparum parasites

artículo científico publicado en 2014

PI3K drives the de novo synthesis of coenzyme A from vitamin B5

artículo científico publicado en 2022

Redox-dependent lipoylation of mitochondrial proteins in Plasmodium falciparum

artículo científico publicado en 2014

Synthesis and Evaluation of Fluoroalkyl Phosphonyl Analogues of 2- C-Methylerythritol Phosphate as Substrates and Inhibitors of IspD from Human Pathogens

artículo científico publicado en 2018

Targeting the Unique Mechanism of Bacterial 1-Deoxy-d-xylulose-5-phosphate Synthase

artículo científico publicado en 2018

Toward Understanding the Chemistry and Biology of 1-Deoxy-d-xylulose 5-Phosphate (DXP) Synthase: A Unique Antimicrobial Target at the Heart of Bacterial Metabolism

scientific article published on 11 September 2018