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A Common Mechanism Links Activities of Butyrate in the Colon

artículo científico publicado en 2018

A Dietary Fiber-Deprived Gut Microbiota Degrades the Colonic Mucus Barrier and Enhances Pathogen Susceptibility

artículo científico publicado en 2016

A Network Medicine Approach to Investigation and Population-based Validation of Disease Manifestations and Drug Repurposing for COVID-19

artículo científico publicado en 2020

A Stem-Cell-Derived Platform Enables Complete Cryptosporidium Development In Vitro and Genetic Tractability

scientific article published on 20 June 2019

A common mechanism links activities of butyrate in the colon

artículo científico publicado en 2017

A common role for Atg16L1, Atg5 and Atg7 in small intestinal Paneth cells and Crohn disease

artículo científico publicado en 2009

A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells

artículo científico publicado en 2008

A network medicine approach to investigation and population-based validation of disease manifestations and drug repurposing for COVID-19

artículo científico publicado en 2020

A novel strategy to increase the proliferative potential of adult human β-cells while maintaining their differentiated phenotype.

artículo científico publicado en 2013

A screen of Crohn's disease-associated microbial metabolites identifies ascorbate as a novel metabolic inhibitor of activated human T cells.

artículo científico publicado en 2018

Abnormal Small Intestinal Epithelial Microvilli in Patients With Crohn's Disease

artículo científico publicado en 2018

Accounting for reciprocal host-microbiome interactions in experimental science

artículo científico publicado en 2016

Activated macrophages are an adaptive element of the colonic epithelial progenitor niche necessary for regenerative responses to injury

artículo científico publicado en 2004

Adaptive immunity restricts replication of novel murine astroviruses

artículo científico publicado en 2012

Altered intestinal ACE2 levels are associated with inflammation, severe disease and response to anti-cytokine therapy in IBD

artículo científico publicado en 2020

An antibiotic-responsive mouse model of fulminant ulcerative colitis

artículo científico publicado en 2008

Angiogenins: a new class of microbicidal proteins involved in innate immunity

artículo científico publicado en 2003

Assigning function to symbionts

artículo científico publicado en 2018

Atg14 protects the intestinal epithelium from TNF-triggered villus atrophy

scientific article published on 03 April 2019

Atg16L1 T300A variant decreases selective autophagy resulting in altered cytokine signaling and decreased antibacterial defense

artículo científico publicado en 2014

Atg16l1 is required for autophagy in intestinal epithelial cells and protection of mice from Salmonella infection

artículo científico publicado en 2013

Autophagy and Intestinal Homeostasis ⬇️

artículo científico publicado el 3 de diciembre de 2012

Autophagy proteins are required for club cell structure and function in airways

artículo científico publicado en 2019

Autophagy proteins control goblet cell function by potentiating reactive oxygen species production

scientific journal article

B cell-derived IL-4 acts on podocytes to induce proteinuria and foot process effacement.

artículo científico publicado en 2017

BHLHE40 Promotes TH2 Cell-Mediated Antihelminth Immunity and Reveals Cooperative CSF2RB Family Cytokines

artículo científico publicado en 2020

Bhlhe40 mediates tissue-specific control of macrophage proliferation in homeostasis and type 2 immunity

scientific article published on 06 May 2019

Biofilm Formation and Virulence of Shigella flexneri Are Modulated by pH of Gastrointestinal Tract

artículo científico publicado en 2021

Breaking the connection: displacement of the desmosomal plaque protein desmoplakin from cell-cell interfaces disrupts anchorage of intermediate filament bundles and alters intercellular junction assembly

artículo científico publicado en 1996

Butyrate and bioactive proteolytic form of Wnt-5a regulate colonic epithelial proliferation and spatial development.

artículo científico publicado en 2016

Cellular differentiation: Potential insight into butyrate paradox?

scientific article published on 27 February 2018

Challenges in IBD Research: Preclinical Human IBD Mechanisms

scientific article published on 01 May 2019

Challenges in IBD research: update on progress and prioritization of the CCFA's research agenda

scientific article published on March 2013

Colitogenic Bacteroides thetaiotaomicron Antigens Access Host Immune Cells in a Sulfatase-Dependent Manner via Outer Membrane Vesicles

artículo científico publicado en 2015

Colonic epithelial response to injury requires Myd88 signaling in myeloid cells

artículo científico publicado en 2012

Commensal Bacteroides species induce colitis in host-genotype-specific fashion in a mouse model of inflammatory bowel disease

artículo científico publicado en 2011

Contributions made by CDC25 phosphatases to proliferation of intestinal epithelial stem and progenitor cells

artículo científico publicado en 2011

Counteracting stem cell expansion during wound repair: distinct roles of non-canonical Wnt and TGF-β.

artículo científico publicado en 2013

Crohn disease: a current perspective on genetics, autophagy and immunity

artículo científico publicado en 2011

Current concepts in chronic inflammatory diseases: Interactions between microbes, cellular metabolism, and inflammation

artículo científico publicado en 2016

Deciphering the 'black box' of the intestinal stem cell niche: taking direction from other systems

artículo científico publicado en 2008

Deep Learning Global Glomerulosclerosis in Transplant Kidney Frozen Sections

scientific article published on 27 June 2018

Deletion of p38-alpha mitogen-activated protein kinase within the intestinal epithelium promotes colon tumorigenesis ⬇️

artículo científico publicado el 1 de agosto de 2012

Desmoplakin expression and distribution in cultured rat bladder epithelial cells of varying tumorigenic potential

artículo científico publicado en 1991

Development of a primary mouse intestinal epithelial cell monolayer culture system to evaluate factors that modulate IgA transcytosis

artículo científico publicado en 2013

Development of an enhanced human gastrointestinal epithelial culture system to facilitate patient-based assays.

artículo científico publicado en 2014

Developmental regulation of intestinal angiogenesis by indigenous microbes via Paneth cells

artículo científico publicado en 2002

Diet modulates colonic T cell responses by regulating the expression of a Bacteroides thetaiotaomicron antigen

artículo científico publicado en 2019

Discs-large homolog 1 regulates smooth muscle orientation in the mouse ureter

artículo científico publicado en 2006

Disease-specific alterations in the enteric virome in inflammatory bowel disease

artículo científico publicado en 2015

Diverse adult stem cells share specific higher-order patterns of gene expression.

artículo científico

Diversity of the autochthonous colonic microbiota

artículo científico publicado en 2011

Dnmt1 is essential to maintain progenitors in the perinatal intestinal epithelium

artículo científico publicado en 2015

ELMO1 regulates the induction of autophagy and bacterial clearance during enteric infection.

artículo científico publicado en 2017

Effects of a gut pathobiont in a gnotobiotic mouse model of childhood undernutrition

artículo científico publicado en 2016

Efficient colonic mucosal wound repair requires Trem2 signaling

scholarly article

Epithelial Cell Biomarkers Are Predictive of Response to Biologic Agents in Crohn's Disease

scientific article published on 23 September 2020

Extranuclear sequestration of phospho-Jun N-terminal kinase and distorted villi produced by activated Rac1 in the intestinal epithelium of chimeric mice

artículo científico publicado en 2001

Fasting protects mice from lethal DNA damage by promoting small intestinal epithelial stem cell survival.

artículo científico publicado en 2015

Fgf9 signaling regulates small intestinal elongation and mesenchymal development.

artículo científico publicado en 2008

Functional analysis of desmoplakin domains: specification of the interaction with keratin versus vimentin intermediate filament networks ⬇️

artículo científico publicado el 1 de noviembre de 1993

Functional characterization of IgA-targeted bacterial taxa from undernourished Malawian children that produce diet-dependent enteropathy

artículo científico publicado en 2015

Genetic mosaic analysis based on Cre recombinase and navigated laser capture microdissection

artículo científico publicado en 2000

Genetic variants synthesize to produce paneth cell phenotypes that define subtypes of Crohn's disease.

artículo científico publicado en 2013

Genetics and Pathogenesis of Inflammatory Bowel Disease

artículo científico publicado en 2016

Gremlin 1 identifies a skeletal stem cell with bone, cartilage, and reticular stromal potential.

artículo científico publicado en 2015

Growth factor regulation of prostaglandin-endoperoxide synthase 2 (Ptgs2) expression in colonic mesenchymal stem cells

artículo científico publicado en 2009

Gut-Pancreatic Axis AMPlified in Islets of Langerhans.

artículo científico publicado en 2015

Helicobacter species are potent drivers of colonic T cell responses in homeostasis and inflammation

artículo científico publicado en 2017

Hepatocyte Growth Factor and MET Support Mouse Enteric Nervous System Development, the Peristaltic Response, and Intestinal Epithelial Proliferation in Response to Injury.

artículo científico publicado en 2015

Host genetic susceptibility, dysbiosis, and viral triggers in inflammatory bowel disease.

artículo científico publicado en 2011

Host pathogens. Editorial overview

artículo científico publicado en 2011

Host-microbe interactions shaping the gastrointestinal environment

artículo científico publicado en 2014

IL-6 stimulates intestinal epithelial proliferation and repair after injury

artículo científico publicado en 2014

IL13 activates autophagy to regulate secretion in airway epithelial cells

artículo científico publicado en 2015

IgG "detoxes" the intestinal mucosa

artículo científico publicado en 2015

Igf2bp1 is required for full induction of Ptgs2 mRNA in colonic mesenchymal stem cells in mice.

artículo científico publicado en 2012

Ileal Gene Expression Data from Crohn's Disease Small Bowel Resections Indicate Distinct Clinical Subgroups

artículo científico publicado en 2019

Immune system dysfunction and autoimmune disease in mice lacking Emk (Par-1) protein kinase.

artículo científico publicado en 2001

In Vitro Culture of Cryptosporidium parvum Using Stem Cell-Derived Intestinal Epithelial Monolayers

scientific article published on 01 January 2020

In vitro expansion and genetic modification of gastrointestinal stem cells in spheroid culture.

artículo científico publicado en 2013

Inhibition of Cyclooxygenase-2 Prevents Chronic and Recurrent Cystitis.

artículo científico publicado en 2014

Interaction between smoking and ATG16L1T300A triggers Paneth cell defects in Crohn's disease

scientific article published on 15 October 2018

Intestinal Dysmotility Syndromes following Systemic Infection by Flaviviruses

artículo científico publicado en 2018

Intestinal Stem Cells Live Off the Fat of the Land

artículo científico publicado en 2018

L-WRN conditioned medium for gastrointestinal epithelial stem cell culture shows replicable batch-to-batch activity levels across multiple research teams.

artículo científico publicado en 2019

LRRK2 but not ATG16L1 is associated with Paneth cell defect in Japanese Crohn's disease patients

scientific article published on 23 March 2017

Lactobacillus probiotic protects intestinal epithelium from radiation injury in a TLR-2/cyclo-oxygenase-2-dependent manner.

artículo científico publicado en 2011

Laminin alpha 5 influences the architecture of the mouse small intestine mucosa

artículo científico publicado en 2008

Laser capture microdissection of mouse intestine: characterizing mRNA and protein expression, and profiling intermediary metabolism in specified cell populations

artículo científico publicado en 2002

Living and commuting in intestinal crypts

scientific article published on 01 January 1999

Long-Term Culture Captures Injury-Repair Cycles of Colonic Stem Cells

scientific article published on 07 November 2019

Long-term IL-33-producing epithelial progenitor cells in chronic obstructive lung disease.

artículo científico publicado en 2013

Long-term IL-33–producing epithelial progenitor cells in chronic obstructive lung disease.

artículo científico publicado en 2013

Mapping the consequence of Notch1 proteolysis in vivo with NIP-CRE

artículo científico publicado en 2007

Mesenchymal stem cell therapy of intestinal disease: are their effects systemic or localized?

artículo científico publicado en 2011

Microbiome control of innate reactivity

scientific article published on 22 January 2019

Molecular characterization of mouse gastric epithelial progenitor cells

artículo científico publicado en 2002

Molecular characterization of mouse gastric zymogenic cells.

artículo científico publicado en 2003

Molecular features of adult mouse small intestinal epithelial progenitors

artículo científico publicado en 2003

Molecular properties of adult mouse gastric and intestinal epithelial progenitors in their niches

artículo científico publicado en 2006

Monoclonal Antibodies to Intracellular Stages of Cryptosporidium parvum Define Life Cycle Progression In Vitro.

artículo científico publicado en 2018

Mucosally transplanted mesenchymal stem cells stimulate intestinal healing by promoting angiogenesis

artículo científico publicado en 2015

Mucus, it is not just a static barrier

artículo científico publicado en 2014

Multi-omics of the gut microbial ecosystem in inflammatory bowel diseases

scientific article published on 29 May 2019

Myd88-dependent positioning of Ptgs2-expressing stromal cells maintains colonic epithelial proliferation during injury

artículo científico publicado en 2007

NOD2 status and human ileal gene expression.

scientific article published on October 2010

Notch2-dependent classical dendritic cells orchestrate intestinal immunity to attaching-and-effacing bacterial pathogens

scientific journal article

Notes from some crypt watchers: regulation of renewal in the mouse intestinal epithelium

artículo científico publicado en 1998

Novel mode of ISG15-mediated protection against influenza A virus and Sendai virus in mice

artículo científico publicado en 2014

Organoids in gastrointestinal diseases: from experimental models to clinical translation

artículo científico publicado en 2022

PAI-1 augments mucosal damage in colitis

artículo científico publicado en 2019

Paneth Cell Alterations in the Development and Phenotype of Crohn's Disease

artículo científico publicado en 2016

Paneth cell defects in Crohn's disease patients promote dysbiosis

artículo científico publicado en 2016

Paneth cell development, differentiation, and function: new molecular cues

artículo científico publicado en 2009

Pathogenic simian immunodeficiency virus infection is associated with expansion of the enteric virome

artículo científico publicado en 2012

Patient-derived small intestinal myofibroblasts direct perfused, physiologically responsive capillary development in a microfluidic Gut-on-a-Chip Model

artículo científico publicado en 2020

Peripheral CD103+ dendritic cells form a unified subset developmentally related to CD8alpha+ conventional dendritic cells

artículo científico publicado en 2010

Peripheral education of the immune system by colonic commensal microbiota.

artículo científico publicado en 2011

Peripheral education of the immune system by the colonic microbiota

artículo científico publicado en 2013

Polysaccharide Capsules Equip the Human Symbiont Bacteroides thetaiotaomicron to Modulate Immune Responses to a Dominant Antigen in the Intestine

artículo científico publicado en 2020

Prostaglandin E2 promotes intestinal repair through an adaptive cellular response of the epithelium

artículo científico publicado en 2016

Rac1 mutations produce aberrant epithelial differentiation in the developing and adult mouse small intestine

scientific article published on 01 June 2000

Reciprocal epithelial-mesenchymal FGF signaling is required for cecal development

scientific journal article

Reduced expression of COVID-19 host receptor, ACE2 is associated with small bowel inflammation, more severe disease, and response to anti-TNF therapy in Crohn′s disease

artículo científico publicado en 2020

Representation Learning for Person or Entity-Centric Knowledge Graphs: An Application in Healthcare

artículo científico publicado en 2023

Response from Jeffrey I. Gordon et al.: Commensal bacteria make a difference

artículo científico publicado en 2003

Response of small intestinal epithelial cells to acute disruption of cell division through CDC25 deletion

scholarly article

Role of autophagy and autophagy genes in inflammatory bowel disease

artículo científico publicado en 2009

Role of microbes in the adaptation of the colonic epithelial progenitor niche during injury

scientific article published on April 2008

Role of viruses and bacteria-virus interactions in autoimmunity

artículo científico publicado en 2014

Runx3 specifies lineage commitment of innate lymphoid cells

artículo científico publicado en 2015

Sorting mouse jejunal epithelial cells with CD24 yields a population with characteristics of intestinal stem cells

artículo científico publicado en 2010

Spatial and temporal stability of paneth cell phenotypes in Crohn's disease: implications for prognostic cellular biomarker development

artículo científico publicado en 2014

Spatial organization of intestinal microbiota in the mouse ascending colon

artículo científico publicado en 2010

Structure and function of desmosomal transmembrane core and plaque molecules

artículo científico publicado en 1994

Structure of Desmoplakin and Its Association with Intermediate Filaments ⬇️

artículo científico publicado el 1 de noviembre de 1992

Survival signal REG3α prevents crypt apoptosis to control acute gastrointestinal graft-versus-host disease

artículo científico publicado en 2018

Temporal Regulation of the Bacterial Metabolite Deoxycholate during Colonic Repair Is Critical for Crypt Regeneration

artículo científico publicado en 2018

The Colonic Crypt Protects Stem Cells from Microbiota-Derived Metabolites

artículo científico publicado en 2016

The Colonic Crypt Protects Stem Cells from Microbiota-Derived Metabolites

artículo científico publicado en 2016

The Intestinal Microbiome Restricts Alphavirus Infection and Dissemination through a Bile Acid-Type I IFN Signaling Axis

artículo científico publicado en 2020

The desmoplakin carboxyl terminus coaligns with and specifically disrupts intermediate filament networks when expressed in cultured cells ⬇️

artículo científico publicado el 1 de marzo de 1992

The maturation of mucus-secreting gastric epithelial progenitors into digestive-enzyme secreting zymogenic cells requires Mist1

artículo científico publicado en 2007

The microbial metabolite desaminotyrosine protects from influenza through type I interferon.

artículo científico publicado en 2017

The role of autophagy in Paneth cell differentiation and secretion

artículo científico publicado en 2009

The role of stromal stem cells in tissue regeneration and wound repair.

artículo científico publicado en 2009

The stem cell niche

artículo científico publicado en 2009

The young and the Wnt-less: transplantable fetal intestinal spheroids without Wnts.

artículo científico publicado en 2013

Tracking cell lineage to rediscover (again) the switch from ciliated to mucous cells

artículo científico publicado en 2011

Type I interferons link viral infection to enhanced epithelial turnover and repair.

artículo científico publicado en 2014

Unique and redundant functions of NKp46+ ILC3s in models of intestinal inflammation

artículo científico publicado en 2015

Vav proteins are necessary for correct differentiation of mouse cecal and colonic enterocytes.

artículo científico publicado en 2009

Vertically transmitted faecal IgA levels determine extra-chromosomal phenotypic variation

artículo científico publicado en 2015

Viral interactions with the host and microbiota in the intestine ⬇️

artículo científico publicado el 22 de mayo de 2012

Virus-plus-susceptibility gene interaction determines Crohn's disease gene Atg16L1 phenotypes in intestine

artículo científico publicado en 2010

Wnt5a Potentiates TGF-β Signaling to Promote Colonic Crypt Regeneration After Tissue Injury ⬇️

artículo científico publicado el 6 de septiembre de 2012

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